Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model

Cancer Research

Volumn 62, Issue 16, 2002, Pages 4767-4772

  Cheng, Jonathan D ^a   Dunbrack Jr , Roland L ^a   Valianou, Matthildi ^a   Rogatko, André ^a   Alpaugh, R Katherine ^a   Weiner, Louis M ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; DIPEPTIDYL PEPTIDASE; FIBROBLAST ACTIVATION PROTEIN; FIBROBLAST ACTIVATION PROTEIN ANTIBODY; MEMBRANE PROTEIN; POLYCLONAL ANTIBODY; PROTEIN; PROTEIN ANTIBODY; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER MODEL; CELL STRAIN HT29; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN STRUCTURE; RABBIT; SCID MOUSE; TUMOR GROWTH; XENOGRAFT;

ANIMALS; ANTIBODIES; ANTIGENS, NEOPLASM; CELL DIVISION; DIPEPTIDYL PEPTIDASES; DISEASE MODELS, ANIMAL; GROWTH SUBSTANCES; HT29 CELLS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, SCID; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SERINE ENDOPEPTIDASES; TRANSFECTION; TUMOR MARKERS, BIOLOGICAL; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0037102412     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Mouse fibroblast activation protein: Molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers
2. Molecular cloning of fibroblast activation protein α, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers
3. Mouse fibroblast-activation protein: Conserved Fap gene organization and biochemical function as a serine protease
4. Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts
5. Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers
6. Substrate- and pH-dependent contribution of oxyaion binding site to the catalysis of prolyl oligopeptidase, a paradigm of the serine oligopeptidase family
7. Gapped BLAST PSI-BLAST: A new generation of protein database search programs
8. Antibody targeting in metastatic colon cancer: A Phase I study of monoclonal antibody F19 against a cell-surface protein of reactive tumor stromal fibroblasts
9. Stromal involvement in malignant growth
10. Effects of human breast fibroblasts on growth and 17β-estradiol dehydrogenase activity of MCF-7 cells in culture
11. Fibroblast-mediated acceleration of human epithelial tumor growth in vivo
12. Mitogenicity of human fibroblasts in vivo for human breast cancer cells
13. Proteases as prognostic markers in cancer
14. Matrix metalloproteinases in tumor invasion and metastasis
15. Proteases in invasion: Matrix metalloproteinases
16. Cell adhesion molecules in the development and progression of malignant melanoma
17. The urokinase-type plasminogen activator system in cancer metastasis: A review
18. CD26/dipeptidyl peptidase IV in context. The different roles of a multifunctional ectoenzyme in malignant transformation
19. Characteristics of a human cell line transformed by DNA from human adenovirus type 5
20. Lung endothelial dipeptidyl peptidase IV promotes adhesion and metastasis of rat breast cancer cells via tumor cell surface-associated fibronectin
21. Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
22. Cell-surface glycoproteins of human sarcomas: Differential expression in normal and malignant tissues and cultured cells