IRE1 impairs insulin signaling transduction of fructose-fed mice via JNK independent of excess lipid

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 1, 2015, Pages 156-165

  Sun, Ruo Qiong ^a   Wang, Hao ^a   Zeng, Xiao Yi ^a   Chan, Stanley M H ^a   Li, Song Pei ^a   Jo, Eunjung ^a   Leung, Sit Lam ^a   Molero, Juan C ^a   Ye, Ji Ming ^a  

^a RMIT UNIVERSITY   (Australia)

Author keywords

Hepatic steatosis; High carbohydrate diet; Insulin signaling; UPR signaling pathways

Indexed keywords

FRUCTOSE; GLUCOSE; INSULIN; PROTEIN IRE1; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL; ERN2 PROTEIN, MOUSE; MEMBRANE PROTEIN; PROTEIN SERINE THREONINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FATTY ACID SYNTHESIS; FATTY LIVER; GLUCOSE TOLERANCE; INSULIN SENSITIVITY; LIPID STORAGE; MALE; MOUSE; NONHUMAN; PROTEIN CONTENT; SIGNAL TRANSDUCTION; WHITE ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; GENETICS; INSULIN RESISTANCE; METABOLISM; PHYSIOLOGY; UNFOLDED PROTEIN RESPONSE;

MUS;

ANIMALS; FRUCTOSE; INSULIN; INSULIN RESISTANCE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TRIGLYCERIDES; UNFOLDED PROTEIN RESPONSE;

EID: 84913582453     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.11.017     Document Type: Article

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