Fructose ingestion and cerebral, metabolic, and satiety responses

JAMA

Volumn 309, Issue 1, 2013, Pages 85-86

  Purnell, Jonathan Q ^a   Fair, Damien A ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APPETITE; BOLD SIGNAL; BRAIN BLOOD FLOW; BRAIN FUNCTION; EDITORIAL; FOOD INTAKE; FRUCTOSE INGESTION; FRUCTOSE METABOLISM; HUMAN; METABOLISM; NONHUMAN; OBESITY; PRIORITY JOURNAL; SATIETY; SUGAR INTAKE; WEIGHT GAIN;

EID: 84871774252     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2012.190505     Document Type: Editorial

References (15)

1. Sievenpiper JL, de Souza RJ, Jenkins DJ. Sugar: fruit fructose is still healthy. Nature. 2012;482(7386):470.
2. Cavadini C, Siega-Riz AM, Popkin BM. US adolescent food intake trends from 1965 to 1996. West J Med. 2000;173(6):378-383.
3. Mozaffarian D, Hao T, Rimm EB, Willett WC, Hu FB. Changes in diet and lifestyle and long-term weight gain in women and men. N Engl J Med. 2011; 364(25):2392-2404.
4. Sievenpiper JL, de Souza RJ, Mirrahimi A, et al. Effect of fructose on body weight in controlled feeding trials: a systematic review and meta-analysis. Ann Intern Med. 2012;156(4):291-304.
5. Miller CC, Martin RJ, Whitney ML, Edwards GL. Intracerebroventricular injection of fructose stimulates feeding in rats. Nutr Neurosci. 2002;5(5):359-362.
6. Jürgens H, Haass W, Castañeda TR, et al. Consuming fructose-sweetened beverages increases body adiposity in mice. Obes Res. 2005;13(7):1146-1156.
7. Lane MD, Cha SH. Effect of glucose and fructose on food intake via malonyl-CoA signaling in the brain. Biochem Biophys Res Commun. 2009; 382(1):1-5.
8. Page KA, Chan O, Arora J, et al. Effects of fructose vs glucose on regional cerebral blood flow in brain regions involved with appetite and reward pathways. JAMA. 2013;309(1):63-70.
9. Biswal B, Yetkin FZ, Haughton VM, Hyde JS. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med. 1995; 34(4):537-541.
10. Wang GJ, Volkow ND, Fowler JS. The role of dopamine in motivation for food in humans: implications for obesity. Expert Opin Ther Targets. 2002;6(5):601-609.
11. Hallschmid M, Benedict C, Schultes B, Fehm HL, Born J, Kern W. Intranasal insulin reduces body fat in men but not in women. Diabetes. 2004;53(11):3024-3029.
12. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL. A default mode of brain function. Proc Natl Acad Sci U S A. 2001;98(2):676-682.
13. Dosenbach NU, Fair DA, Cohen AL, Schlaggar BL, Petersen SE. A dualnetworks architecture of top-down control. Trends Cogn Sci. 2008;12(3):99-105.
14. Qi Q, Chu AY, Kang JH, et al. Sugar-sweetened beverages and genetic risk of obesity. N Engl J Med. 2012;367(15):1387-1396.
15. Ebbeling CB, Feldman HA, Chomitz VR, et al. A randomized trial of sugarsweetened beverages and adolescent body weight. N Engl J Med. 2012;367 (15):1407-1416.