Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes

Genes and Development

Volumn 28, Issue 22, 2014, Pages 2498-2517

  Lykke Andersen, Søren ^a   Chen, Yun ^b   Ardal, Britt R ^a   Lilje, Berit ^b   Waage, Johannes ^b,c   Sandelin, Albin ^b   Jensen, Torben Heick ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Endonucleolytic RNA cleavage; Intron encoded snoRNA; Nonsense mediated decay; Regulation of snoRNA expression; RNA decapping; snoRNA host genes

Indexed keywords

SMALL NUCLEOLAR RNA; TRANSCRIPTOME; ENDONUCLEASE; ISOPROTEIN; SMG6 PROTEIN, HUMAN; TELOMERASE;

ALTERNATIVE RNA SPLICING; ARTICLE; CYTOLYSIS; ENDONUCLEOLYSIS; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; HUMAN; INTRON; NONSENSE MEDIATED MRNA DECAY; RNA DEGRADATION; GENETICS; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY; RNA SPLICING;

ENDONUCLEASES; HEK293 CELLS; HUMANS; NONSENSE MEDIATED MRNA DECAY; PROTEIN ISOFORMS; RNA SPLICING; RNA, SMALL NUCLEOLAR; TELOMERASE;

EID: 84910640414     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.246538.114     Document Type: Article

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