SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay

Genes and Development

Volumn 23, Issue 9, 2009, Pages 1091-1105

  Yamashita, Akio ^a,b   Izumi, Natsuko ^a   Kashima, Isao ^a,g   Ohnishi, Tetsuo ^a,h   Saari, Bonnie ^c   Katsuhata, Yukiko ^a   Muramatsu, Reiko ^a,b   Morita, Tomoko ^a   Iwamatsu, Akihiro ^d   Hachiya, Takahisa ^e   Kurata, Rie ^a   Hirano, Hisashi ^f   Anderson, Philip ^c   Ohno, Shigeo ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d Protein Research Network Inc   (Japan)

^e Medical & Biological Laboratories Co Ltd   (Japan)

^f YOKOHAMA CITY UNIVERSITY   (Japan)

^g MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

^h RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

MRNA surveillance; MRNP remodeling; NMD; PIKK; SMG 1; Translation termination; UPF1

Indexed keywords

MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN ERF1; PROTEIN ERF3; PROTEIN KINASE; PROTEIN SUBUNIT; PROTEIN UPF1; RIBONUCLEOPROTEIN; SMG 1 KINASE; SMG 8 KINASE; SMG 9 KINASE; TRANSCRIPTION FACTOR; TRANSLATION TERMINATION FACTOR; UNCLASSIFIED DRUG; 4 METHOXY 1 TYROSYL GAMMA GLUTAMYL CYSTEINYL GLYCINE; 4-METHOXY-1-TYROSYL-GAMMA-GLUTAMYL-CYSTEINYL-GLYCINE; CAENORHABDITIS ELEGANS PROTEIN; DRUG DERIVATIVE; GLUTATHIONE; MULTIENZYME COMPLEX; SMG 1 PROTEIN, C ELEGANS; SMG-1 PROTEIN, C ELEGANS; SMG1 PROTEIN, HUMAN;

ARTICLE; CAENORHABDITIS ELEGANS; CODON; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; EXON; GENE DELETION; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; NONSENSE MEDIATED MRNA DECAY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RIBOSOME; RNA DEGRADATION; RNA SPLICING; TRANSCRIPTION TERMINATION; ANIMAL; ENZYMOLOGY; GENE EXPRESSION REGULATION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RNA STABILITY; STOP CODON;

MAMMALIA; NEMATODA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CODON, NONSENSE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE; HELA CELLS; HUMANS; MULTIENZYME COMPLEXES; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN SUBUNITS; RIBOSOMES; RNA STABILITY;

EID: 65449178454     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1767209     Document Type: Article

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