Endosomal localization of TLR8 confers distinctive proteolytic processing on human myeloid cells

Journal of Immunology

Volumn 193, Issue 10, 2014, Pages 5118-5128

  Ishii, Noriko ^a   Funami, Kenji ^a   Tatematsu, Megumi ^a   Seya, Tsukasa ^a   Matsumoto, Misako ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN; FURIN; MICRORNA; RNA; SINGLE STRANDED RNA; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; LIGAND; PROPROTEIN CONVERTASE 1; PROTEIN BINDING; TLR7 PROTEIN, HUMAN; TLR8 PROTEIN, HUMAN; TLR9 PROTEIN, HUMAN; VIRUS RNA;

AMINO TERMINAL SEQUENCE; ARTICLE; BONE MARROW CELL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOSOME; HUMAN; HUMAN CELL; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LEUCINE RICH REPEAT; MACROPHAGE; MOLECULAR RECOGNITION; MONOCYTE; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; VIRUS DETECTION; AMINO ACID SEQUENCE; CHEMISTRY; CYTOLOGY; GENE EXPRESSION; GENETICS; HEK293 CELL LINE; LYSOSOME; METABOLISM; MOLECULAR GENETICS; PRIMARY CELL CULTURE; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; CATHEPSINS; ENDOSOMES; GENE EXPRESSION; HEK293 CELLS; HUMANS; LIGANDS; LYSOSOMES; MACROPHAGES; MICRORNAS; MOLECULAR SEQUENCE DATA; MONOCYTES; PRIMARY CELL CULTURE; PROPROTEIN CONVERTASE 1; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; RNA, VIRAL; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; TOLL-LIKE RECEPTOR 9;

EID: 84910153079     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401375     Document Type: Article

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