Structural reorganization of the toll-like receptor 8 dimer induced by agonistic ligands

Science

Volumn 339, Issue 6126, 2013, Pages 1426-1429

  Tanji, Hiromi ^a,b   Ohto, Umeharu ^a,b   Shibata, Takuma ^a   Miyake, Kensuke ^a   Shimizu, Toshiyuki ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b Department of Microbiology and Immunology Institute of Medical Science University of Tokyo ^*  (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; LEUCINE; LEUCINE RICH REPEAT 14; LEUCINE RICH REPEAT 15; LIGAND; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; UNCLASSIFIED DRUG;

BIOCHEMISTRY; CHEMICAL BINDING; CRYSTAL STRUCTURE; HOMINID; IMMUNE RESPONSE; INNATE BEHAVIOR; LIGAND; RNA; SIGNALING;

ARTICLE; CRYSTAL STRUCTURE; DIMERIZATION; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

EID: 84875425019     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1229159     Document Type: Article

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