RNA recognition by human TLR8 can lead to autoimmune inflammation

Journal of Experimental Medicine

Volumn 210, Issue 13, 2013, Pages 2903-2919

  Guiducci, Cristiana ^a   Gong, Mei ^a   Cepika, Alma Martina ^b   Xu, Zhaohui ^b   Tripodo, Claudio ^c   Bennett, Lynda ^b   Crain, Chad ^a   Quartier, Pierre ^d   Cush, John J ^b   Pascual, Virginia ^b,e   Coffman, Robert L ^a   Barrat, Franck J ^a  

^a Dynavax Technologies Corporation   (United States)

^b BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^c UNIVERSITY OF PALERMO   (Italy)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

^e TEXAS SCOTTISH RITE HOSPITAL FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; BAFILOMYCIN A1; COLLAGEN; CYTOKINE; DNA ANTIBODY; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GELATINASE B; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; IONOMYCIN; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; RIBONUCLEOPROTEIN ANTIBODY; RNA; STROMELYSIN; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CHIMERA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; IMMUNOSTIMULATION; INFLAMMATION; INNATE IMMUNITY; JOINT; LIVER; MOUSE; NONHUMAN; PANCREAS; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; RODENT; SALIVARY GLAND; SPECIES COMPARISON; SPLEEN; SURVIVAL; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE;

ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, JUVENILE; AUTOIMMUNITY; CHILD; COLLAGEN; FEMALE; GENE EXPRESSION PROFILING; HUMANS; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RNA; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; TRANSGENES;

EID: 84890840281     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20131044     Document Type: Article

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