메뉴 건너뛰기




Volumn 8, Issue 8, 2012, Pages

Asparagine Endopeptidase Controls Anti-Influenza Virus Immune Responses through TLR7 Activation

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; CYTOKINE; LEGUMAIN; TOLL LIKE RECEPTOR 7; VIRUS ANTIBODY;

EID: 84866145569     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002841     Document Type: Article
Times cited : (55)

References (44)
  • 1
    • 80052940381 scopus 로고    scopus 로고
    • Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection
    • Teijaro JR, Walsh KB, Cahalan S, Fremgen DM, Roberts E, et al. (2011) Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection. Cell 146: 980-991.
    • (2011) Cell , vol.146 , pp. 980-991
    • Teijaro, J.R.1    Walsh, K.B.2    Cahalan, S.3    Fremgen, D.M.4    Roberts, E.5
  • 2
    • 33947108477 scopus 로고    scopus 로고
    • A question of self-preservation: immunopathology in influenza virus infection
    • La Gruta NL, Kedzierska K, Stambas J, Doherty PC, (2007) A question of self-preservation: immunopathology in influenza virus infection. Immunol Cell Biol 85: 85-92.
    • (2007) Immunol Cell Biol , vol.85 , pp. 85-92
    • La Gruta, N.L.1    Kedzierska, K.2    Stambas, J.3    Doherty, P.C.4
  • 3
    • 78650642085 scopus 로고    scopus 로고
    • Influenza A infection enhances cross-priming of CD8+ T cells to cell-associated antigens in a TLR7- and type I IFN-dependent fashion
    • Wei J, Waithman J, Lata R, Mifsud NA, Cebon J, et al. (2010) Influenza A infection enhances cross-priming of CD8+ T cells to cell-associated antigens in a TLR7- and type I IFN-dependent fashion. J Immunol 185: 6013-6022.
    • (2010) J Immunol , vol.185 , pp. 6013-6022
    • Wei, J.1    Waithman, J.2    Lata, R.3    Mifsud, N.A.4    Cebon, J.5
  • 4
    • 76949094170 scopus 로고    scopus 로고
    • Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenza
    • Ballesteros-Tato A, Leon B, Lund FE, Randall TD, (2010) Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenza. Nat Immunol 11: 216-224.
    • (2010) Nat Immunol , vol.11 , pp. 216-224
    • Ballesteros-Tato, A.1    Leon, B.2    Lund, F.E.3    Randall, T.D.4
  • 6
    • 38949117752 scopus 로고    scopus 로고
    • Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination
    • Koyama S, Ishii KJ, Kumar H, Tanimoto T, Coban C, et al. (2007) Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination. J Immunol 179: 4711-4720.
    • (2007) J Immunol , vol.179 , pp. 4711-4720
    • Koyama, S.1    Ishii, K.J.2    Kumar, H.3    Tanimoto, T.4    Coban, C.5
  • 7
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C, (2004) Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303: 1529-1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis e Sousa, C.5
  • 8
    • 80053092279 scopus 로고    scopus 로고
    • Increased MDSC accumulation and Th2 biased response to influenza A virus infection in the absence of TLR7 in mice
    • Jeisy-Scott V, Davis WG, Patel JR, Bowzard JB, Shieh WJ, et al. (2011) Increased MDSC accumulation and Th2 biased response to influenza A virus infection in the absence of TLR7 in mice. PloS one 6: e25242.
    • (2011) PloS One , vol.6
    • Jeisy-Scott, V.1    Davis, W.G.2    Patel, J.R.3    Bowzard, J.B.4    Shieh, W.J.5
  • 9
    • 58049220365 scopus 로고    scopus 로고
    • Pattern recognition receptors and control of adaptive immunity
    • Palm NW, Medzhitov R, (2009) Pattern recognition receptors and control of adaptive immunity. Immunol Rev 227: 221-233.
    • (2009) Immunol Rev , vol.227 , pp. 221-233
    • Palm, N.W.1    Medzhitov, R.2
  • 10
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
    • Kawai T, Akira S, (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11: 373-384.
    • (2010) Nat Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 12
    • 56349114913 scopus 로고    scopus 로고
    • Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
    • Park B, Brinkmann MM, Spooner E, Lee CC, Kim YM, et al. (2008) Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9. Nat Immunol 9: 1407-1414.
    • (2008) Nat Immunol , vol.9 , pp. 1407-1414
    • Park, B.1    Brinkmann, M.M.2    Spooner, E.3    Lee, C.C.4    Kim, Y.M.5
  • 13
    • 57349191215 scopus 로고    scopus 로고
    • The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
    • Ewald SE, Lee BL, Lau L, Wickliffe KE, Shi GP, et al. (2008) The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor. Nature 456: 658-662.
    • (2008) Nature , vol.456 , pp. 658-662
    • Ewald, S.E.1    Lee, B.L.2    Lau, L.3    Wickliffe, K.E.4    Shi, G.P.5
  • 15
    • 38849127573 scopus 로고    scopus 로고
    • Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis
    • Asagiri M, Hirai T, Kunigami T, Kamano S, Gober HJ, et al. (2008) Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. Science 319: 624-627.
    • (2008) Science , vol.319 , pp. 624-627
    • Asagiri, M.1    Hirai, T.2    Kunigami, T.3    Kamano, S.4    Gober, H.J.5
  • 16
    • 70449477746 scopus 로고    scopus 로고
    • Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells
    • Sepulveda FE, Maschalidi S, Colisson R, Heslop L, Ghirelli C, et al. (2009) Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells. Immunity 31: 737-748.
    • (2009) Immunity , vol.31 , pp. 737-748
    • Sepulveda, F.E.1    Maschalidi, S.2    Colisson, R.3    Heslop, L.4    Ghirelli, C.5
  • 17
    • 79955743119 scopus 로고    scopus 로고
    • Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase
    • Ewald SE, Engel A, Lee J, Wang M, Bogyo M, et al. (2011) Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase. The J Exp Med 208: 643-651.
    • (2011) The J Exp Med , vol.208 , pp. 643-651
    • Ewald, S.E.1    Engel, A.2    Lee, J.3    Wang, M.4    Bogyo, M.5
  • 18
    • 14044267522 scopus 로고    scopus 로고
    • Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus
    • Guillot L, Le Goffic R, Bloch S, Escriou N, Akira S, et al. (2005) Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus. J Biol Chem 280: 5571-5580.
    • (2005) J Biol Chem , vol.280 , pp. 5571-5580
    • Guillot, L.1    Le Goffic, R.2    Bloch, S.3    Escriou, N.4    Akira, S.5
  • 19
    • 0022930702 scopus 로고
    • Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism
    • Sen R, Baltimore D, (1986) Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism. Cell 47: 921-928.
    • (1986) Cell , vol.47 , pp. 921-928
    • Sen, R.1    Baltimore, D.2
  • 20
    • 80052334325 scopus 로고    scopus 로고
    • Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein
    • Le Goffic R, Leymarie O, Chevalier C, Rebours E, Da Costa B, et al. (2011) Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein. PLoS Pathog 7: e1002202.
    • (2011) PLoS Pathog , vol.7
    • Le Goffic, R.1    Leymarie, O.2    Chevalier, C.3    Rebours, E.4    Da Costa, B.5
  • 21
    • 0041876230 scopus 로고    scopus 로고
    • Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice
    • Shirahama-Noda K, Yamamoto A, Sugihara K, Hashimoto N, Asano M, et al. (2003) Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice. J Biol Chem 278: 33194-33199.
    • (2003) J Biol Chem , vol.278 , pp. 33194-33199
    • Shirahama-Noda, K.1    Yamamoto, A.2    Sugihara, K.3    Hashimoto, N.4    Asano, M.5
  • 22
    • 21044432199 scopus 로고    scopus 로고
    • Asparagine endopeptidase is not essential for class II MHC antigen presentation but is required for processing of cathepsin L in mice
    • Maehr R, Hang HC, Mintern JD, Kim YM, Cuvillier A, et al. (2005) Asparagine endopeptidase is not essential for class II MHC antigen presentation but is required for processing of cathepsin L in mice. J Immunol 174: 7066-7074.
    • (2005) J Immunol , vol.174 , pp. 7066-7074
    • Maehr, R.1    Hang, H.C.2    Mintern, J.D.3    Kim, Y.M.4    Cuvillier, A.5
  • 23
    • 48749132777 scopus 로고    scopus 로고
    • Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms
    • Hou B, Reizis B, DeFranco AL, (2008) Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and-extrinsic mechanisms. Immunity 29: 272-282.
    • (2008) Immunity , vol.29 , pp. 272-282
    • Hou, B.1    Reizis, B.2    DeFranco, A.L.3
  • 24
    • 0141755165 scopus 로고    scopus 로고
    • Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo
    • Li DN, Matthews SP, Antoniou AN, Mazzeo D, Watts C, (2003) Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo. J Biol Chem 278: 38980-38990.
    • (2003) J Biol Chem , vol.278 , pp. 38980-38990
    • Li, D.N.1    Matthews, S.P.2    Antoniou, A.N.3    Mazzeo, D.4    Watts, C.5
  • 25
    • 33745825951 scopus 로고    scopus 로고
    • NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells
    • Savina A, Jancic C, Hugues S, Guermonprez P, Vargas P, et al. (2006) NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. Cell 126: 205-218.
    • (2006) Cell , vol.126 , pp. 205-218
    • Savina, A.1    Jancic, C.2    Hugues, S.3    Guermonprez, P.4    Vargas, P.5
  • 26
    • 64449088219 scopus 로고    scopus 로고
    • The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells
    • Savina A, Peres A, Cebrian I, Carmo N, Moita C, et al. (2009) The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells. Immunity 30: 544-555.
    • (2009) Immunity , vol.30 , pp. 544-555
    • Savina, A.1    Peres, A.2    Cebrian, I.3    Carmo, N.4    Moita, C.5
  • 27
    • 4644330955 scopus 로고    scopus 로고
    • Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner
    • Rutz M, Metzger J, Gellert T, Luppa P, Lipford GB, et al. (2004) Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner. Eur J Immunol 4: 2541-2550.
    • (2004) Eur J Immunol , vol.4 , pp. 2541-2550
    • Rutz, M.1    Metzger, J.2    Gellert, T.3    Luppa, P.4    Lipford, G.B.5
  • 28
    • 0032542285 scopus 로고    scopus 로고
    • An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation
    • Manoury B, Hewitt EW, Morrice N, Dando PM, Barrett AJ, et al. (1998) An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation. Nature 396: 695-699.
    • (1998) Nature , vol.396 , pp. 695-699
    • Manoury, B.1    Hewitt, E.W.2    Morrice, N.3    Dando, P.M.4    Barrett, A.J.5
  • 29
    • 31344466165 scopus 로고    scopus 로고
    • The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
    • Tabeta K, Hoebe K, Janssen EM, Du X, Georgel P, et al. (2006) The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol 7: 156-164.
    • (2006) Nat Immunol , vol.7 , pp. 156-164
    • Tabeta, K.1    Hoebe, K.2    Janssen, E.M.3    Du, X.4    Georgel, P.5
  • 30
    • 55849132494 scopus 로고    scopus 로고
    • Innate sensors of influenza virus: clues to developing better intranasal vaccines
    • Ichinohe T, Iwasaki A, Hasegawa H, (2008) Innate sensors of influenza virus: clues to developing better intranasal vaccines. Expert Rev Vaccines 7: 1435-1445.
    • (2008) Expert Rev Vaccines , vol.7 , pp. 1435-1445
    • Ichinohe, T.1    Iwasaki, A.2    Hasegawa, H.3
  • 32
    • 33745684282 scopus 로고    scopus 로고
    • Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia
    • Le Goffic R, Balloy V, Lagranderie M, Alexopoulou L, Escriou N, et al. (2006) Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia. PLoS Pathog 2: e53.
    • (2006) PLoS Pathog , vol.2
    • Le Goffic, R.1    Balloy, V.2    Lagranderie, M.3    Alexopoulou, L.4    Escriou, N.5
  • 33
    • 64049096334 scopus 로고    scopus 로고
    • The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1
    • Thomas PG, Dash P, Aldridge JR Jr, Ellebedy AH, Reynolds C, et al. (2009) The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity 30: 566-575.
    • (2009) Immunity , vol.30 , pp. 566-575
    • Thomas, P.G.1    Dash, P.2    Aldridge Jr., J.R.3    Ellebedy, A.H.4    Reynolds, C.5
  • 34
    • 79951828168 scopus 로고    scopus 로고
    • TLR3-specific double-stranded RNA oligonucleotide adjuvants induce dendritic cell cross-presentation, CTL responses, and antiviral protection
    • Jelinek I, Leonard JN, Price GE, Brown KN, Meyer-Manlapat A, et al. (2011) TLR3-specific double-stranded RNA oligonucleotide adjuvants induce dendritic cell cross-presentation, CTL responses, and antiviral protection. J Immunol 186: 2422-2429.
    • (2011) J Immunol , vol.186 , pp. 2422-2429
    • Jelinek, I.1    Leonard, J.N.2    Price, G.E.3    Brown, K.N.4    Meyer-Manlapat, A.5
  • 35
    • 78650754831 scopus 로고    scopus 로고
    • Inflammasomes as mediators of immunity against influenza virus
    • Pang IK, Iwasaki A, (2011) Inflammasomes as mediators of immunity against influenza virus. Trends Immunol 32: 34-41.
    • (2011) Trends Immunol , vol.32 , pp. 34-41
    • Pang, I.K.1    Iwasaki, A.2
  • 36
    • 14844340568 scopus 로고    scopus 로고
    • Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate
    • Delamarre L, Pack M, Chang H, Mellman I, Trombetta ES, (2005) Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science 307: 1630-1634.
    • (2005) Science , vol.307 , pp. 1630-1634
    • Delamarre, L.1    Pack, M.2    Chang, H.3    Mellman, I.4    Trombetta, E.S.5
  • 37
    • 0037470438 scopus 로고    scopus 로고
    • Activation of lysosomal function during dendritic cell maturation
    • Trombetta ES, Ebersold M, Garrett W, Pypaert M, Mellman I, (2003) Activation of lysosomal function during dendritic cell maturation. Science 299: 1400-1403.
    • (2003) Science , vol.299 , pp. 1400-1403
    • Trombetta, E.S.1    Ebersold, M.2    Garrett, W.3    Pypaert, M.4    Mellman, I.5
  • 38
    • 40749098665 scopus 로고    scopus 로고
    • UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
    • Kim YM, Brinkmann MM, Paquet ME, Ploegh HL, (2008) UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes. Nature 452: 234-238.
    • (2008) Nature , vol.452 , pp. 234-238
    • Kim, Y.M.1    Brinkmann, M.M.2    Paquet, M.E.3    Ploegh, H.L.4
  • 40
    • 47249092785 scopus 로고    scopus 로고
    • Development of TLR inhibitors for the treatment of autoimmune diseases
    • Barrat FJ, Coffman RL, (2008) Development of TLR inhibitors for the treatment of autoimmune diseases. Immunol rev 223: 271-283.
    • (2008) Immunol Rev , vol.223 , pp. 271-283
    • Barrat, F.J.1    Coffman, R.L.2
  • 42
    • 28444451898 scopus 로고    scopus 로고
    • Application of a reversible immortalization system for the generation of proliferation-controlled cell lines
    • May T, Lindenmaier W, Wirth D, Mueller PP, (2004) Application of a reversible immortalization system for the generation of proliferation-controlled cell lines. Cytotechnology 46: 69-78.
    • (2004) Cytotechnology , vol.46 , pp. 69-78
    • May, T.1    Lindenmaier, W.2    Wirth, D.3    Mueller, P.P.4
  • 43
    • 70350244436 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa LPS or flagellin are sufficient to activate TLR-dependent signaling in murine alveolar macrophages and airway epithelial cells
    • Raoust E, Balloy V, Garcia-Verdugo I, Touqui L, Ramphal R, et al. (2009) Pseudomonas aeruginosa LPS or flagellin are sufficient to activate TLR-dependent signaling in murine alveolar macrophages and airway epithelial cells. PloS one 4: e7259.
    • (2009) PloS One , vol.4
    • Raoust, E.1    Balloy, V.2    Garcia-Verdugo, I.3    Touqui, L.4    Ramphal, R.5
  • 44
    • 0036411680 scopus 로고    scopus 로고
    • Cross-presentation of cell-associated antigens by CD8alpha+ dendritic cells is attributable to their ability to internalize dead cells
    • Schulz O, Reis e Sousa C, (2002) Cross-presentation of cell-associated antigens by CD8alpha+ dendritic cells is attributable to their ability to internalize dead cells. Immunology 107: 183-189.
    • (2002) Immunology , vol.107 , pp. 183-189
    • Schulz, O.1    Reis e Sousa, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.