Towards improved membrane protein production in Pichia pastoris: General and specific transcriptional response to membrane protein overexpression

New Biotechnology

Volumn 31, Issue 6, 2014, Pages 538-552

  Vogl, Thomas ^a   Thallinger, Gerhard G ^a,b,c   Zellnig, Guenther ^d   Drew, David ^e   Cregg, James M ^f   Glieder, Anton ^c   Freigassner, Maria ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b Omics Center Graz   (Austria)

^c AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

^d UNIVERSITY OF GRAZ   (Austria)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f KECK GRADUATE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; MACHINERY; MEMBRANES; MITOCHONDRIA; PHYSIOLOGICAL MODELS; YEAST;

ALTERNATIVE OXIDASE; ENZYMATIC ACTIVITIES; HIGH-LEVEL PRODUCTION; METHYLOTROPHIC YEASTS; SUBCELLULAR LOCALIZATIONS; TRANSCRIPTIONAL RESPONSE; TRANSCRIPTOME ANALYSIS; UNFOLDED PROTEIN RESPONSE;

PROTEINS;

MEMBRANE PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HAC1P; TRANSCRIPTOME; UNCLASSIFIED DRUG; GREEN FLUORESCENT PROTEIN;

ARTICLE; BIOREACTOR; BIOSYNTHESIS; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONFOCAL FLUORESCENCE MICROSCOPY; ENDOPLASMIC RETICULUM; FED BATCH REACTOR; FLUORESCENCE MICROSCOPY; GENETIC TRANSCRIPTION; GOLGI COMPLEX; MITOCHONDRION; NONHUMAN; PICHIA PASTORIS; PROTEIN EXPRESSION; PROTEIN OVEREXPRESSION; PROTEIN SYNTHESIS; SECRETORY PATHWAY; UNFOLDED PROTEIN RESPONSE; GENETICS; METABOLISM; PICHIA;

GREEN FLUORESCENT PROTEINS; MEMBRANE PROTEINS; PICHIA; TRANSCRIPTION, GENETIC;

EID: 84910035218     PISSN: 18716784     EISSN: 18764347     Source Type: Journal    
DOI: 10.1016/j.nbt.2014.02.009     Document Type: Article

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