Laboratory evolved biocatalysts for stereoselective syntheses of substituted benzaldehyde cyanohydrins

ChemBioChem

Volumn 9, Issue 1, 2008, Pages 58-61

  Liu, Zhibin ^a   Pscheidt, Beate ^a   Avi, Manuela ^b   Gaisberger, Richard ^a   Hartner, Franz Stefan ^a   Schuster, Christian ^c   Skranc, Wolfgang ^c   Gruber, Karl ^a   Glieder, Anton ^a  

^a RESEARCH CENTRE APPLIED BIOCATALYSIS   (Austria)

^b GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^c DSM Fine Chemicals Austria Nfg GmbH & Co KG   (Netherlands)

Author keywords

Asymmetric synthesis; Directed evolution; Enzyme catalysis; Hydroxynitrile lyase; Pichia pastoris

Indexed keywords

BENZALDEHYDE CYANOHYDRIN; BENZALDEHYDE DERIVATIVE; CYANOHYDRIN; ENZYME VARIANT; HYDROXYNITRILE LYASE; METHIONINE; UNCLASSIFIED DRUG;

ARTICLE; BIOCATALYST; ENZYME ACTIVE SITE; ESCHERICHIA COLI; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PRUNUS; STEREOCHEMISTRY; SYNTHESIS;

ACETONITRILES; AMINO ACID SEQUENCE; BASE SEQUENCE; BENZALDEHYDES; BINDING SITES; CATALYSIS; DIRECTED MOLECULAR EVOLUTION; LYASES; MUTAGENESIS, SITE-DIRECTED; PICHIA; POLYMERASE CHAIN REACTION; PRUNUS; RECOMBINATION, GENETIC; SUBSTRATE SPECIFICITY;

PICHIA PASTORIS;

EID: 38349028590     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200700514     Document Type: Article

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