Independent relationship between amyloid precursor protein (APP) dimerization and γ-secretase processivity

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Jung, Joo In ^a   Premraj, Sasha ^a,b   Cruz, Pedro E ^a   Ladd, Thomas B ^a   Kwak, Yewon ^a   Koo, Edward H ^c   Felsenstein, Kevin M ^a   Golde, Todd E ^a   Ran, Yong ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA HEALTH   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN 38; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; DIMER; GAMMA SECRETASE; MONOMER; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; APP PROTEIN, HUMAN; CULTURE MEDIUM; SECRETASE;

ANIMAL CELL; ARTICLE; DIMERIZATION; ENZYME SUBSTRATE; FEMALE; IN VITRO STUDY; MUTANT; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; ANIMAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; CULTURE MEDIUM; ENZYME LINKED IMMUNOSORBENT ASSAY; HAMSTER; MASS SPECTROMETRY; METABOLISM; MUTATION; PROTEIN TERTIARY STRUCTURE;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; CULTURE MEDIA, CONDITIONED; ENZYME-LINKED IMMUNOSORBENT ASSAY; MASS SPECTROMETRY; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 84908610924     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0111553     Document Type: Article

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