메뉴 건너뛰기




Volumn 40, Issue 5, 2014, Pages 338-346

Circadian disruption in the pathogenesis of metabolic syndrome

Author keywords

Cardiovascular disease; Circadian rhythm; Metabolism

Indexed keywords

GLUCOSE; LIPID; TRANSCRIPTION FACTOR CLOCK;

EID: 84908510371     PISSN: 12623636     EISSN: 18781780     Source Type: Journal    
DOI: 10.1016/j.diabet.2013.12.005     Document Type: Review
Times cited : (102)

References (121)
  • 3
    • 33845971890 scopus 로고    scopus 로고
    • The National Cholesterol Education Program-Adult Treatment Panel III. International Diabetes Federation, and World Health Organization definitions of the metabolic syndrome as predictors of incident cardiovascular disease and diabetes
    • Lorenzo C., Williams K., Hunt K.J., Haffner S.M. The National Cholesterol Education Program-Adult Treatment Panel III. International Diabetes Federation, and World Health Organization definitions of the metabolic syndrome as predictors of incident cardiovascular disease and diabetes. Diabetes Care 2007, 30:8-13.
    • (2007) Diabetes Care , vol.30 , pp. 8-13
    • Lorenzo, C.1    Williams, K.2    Hunt, K.J.3    Haffner, S.M.4
  • 4
    • 25144459980 scopus 로고    scopus 로고
    • The metabolic syndrome-a new worldwide definition
    • Alberti K.G., Zimmet P., Shaw J., Group IDFETFC The metabolic syndrome-a new worldwide definition. Lancet 2005, 36:1059-1062.
    • (2005) Lancet , vol.36 , pp. 1059-1062
    • Alberti, K.G.1    Zimmet, P.2    Shaw, J.3
  • 5
    • 34249883032 scopus 로고    scopus 로고
    • Waist circumference and cardiometabolic risk: a consensus statement from shaping America's health: Association for Weight Management and Obesity Prevention; NAASO, the Obesity Society; the American Society for Nutrition; and the American Diabetes Association
    • Klein S., Allison D.B., Heymsfield S.B., Kelley D.E., Leibel R.L., Nonas C., et al. Waist circumference and cardiometabolic risk: a consensus statement from shaping America's health: Association for Weight Management and Obesity Prevention; NAASO, the Obesity Society; the American Society for Nutrition; and the American Diabetes Association. Diabetes Care 2007, 30:1647-1652.
    • (2007) Diabetes Care , vol.30 , pp. 1647-1652
    • Klein, S.1    Allison, D.B.2    Heymsfield, S.B.3    Kelley, D.E.4    Leibel, R.L.5    Nonas, C.6
  • 6
  • 7
    • 77957198071 scopus 로고    scopus 로고
    • The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis
    • Mottillo S., Filion K.B., Genest J., Joseph L., Pilote L., Poirier P., et al. The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis. J Am Coll Cardiol 2010, 56:1113-1132.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 1113-1132
    • Mottillo, S.1    Filion, K.B.2    Genest, J.3    Joseph, L.4    Pilote, L.5    Poirier, P.6
  • 8
    • 77952096006 scopus 로고    scopus 로고
    • Assessing prediction of diabetes in older adults using different adiposity measures: a 7-year prospective study in 6,923 older men and women
    • Wannamethee S.G., Papacosta O., Whincup P.H., Carson C., Thomas M.C., Lawlor D.A., et al. Assessing prediction of diabetes in older adults using different adiposity measures: a 7-year prospective study in 6,923 older men and women. Diabetologia 2010, 53:890-898.
    • (2010) Diabetologia , vol.53 , pp. 890-898
    • Wannamethee, S.G.1    Papacosta, O.2    Whincup, P.H.3    Carson, C.4    Thomas, M.C.5    Lawlor, D.A.6
  • 10
    • 58149359301 scopus 로고    scopus 로고
    • Vitamin D and type 2 diabetes: are we ready for a prevention trial?
    • Scragg R. Vitamin D and type 2 diabetes: are we ready for a prevention trial?. Diabetes 2008, 57:2565-2566.
    • (2008) Diabetes , vol.57 , pp. 2565-2566
    • Scragg, R.1
  • 11
    • 58149346072 scopus 로고    scopus 로고
    • Baseline serum 25-hydroxy vitamin d is predictive of future glycemic status and insulin resistance: the Medical Research Council Ely Prospective Study 1990-2000
    • Forouhi N.G., Luan J., Cooper A., Boucher B.J., Wareham N.J. Baseline serum 25-hydroxy vitamin d is predictive of future glycemic status and insulin resistance: the Medical Research Council Ely Prospective Study 1990-2000. Diabetes 2008, 57:2619-2625.
    • (2008) Diabetes , vol.57 , pp. 2619-2625
    • Forouhi, N.G.1    Luan, J.2    Cooper, A.3    Boucher, B.J.4    Wareham, N.J.5
  • 12
    • 70349262530 scopus 로고    scopus 로고
    • Vitamin D status and cardiometabolic risk factors in the United States adolescent population
    • Reis J.P., von Muhlen D., Miller E.R., Michos E.D., Appel L.J. Vitamin D status and cardiometabolic risk factors in the United States adolescent population. Pediatrics 2009, 124:e371-e379.
    • (2009) Pediatrics , vol.124 , pp. e371-e379
    • Reis, J.P.1    von Muhlen, D.2    Miller, E.R.3    Michos, E.D.4    Appel, L.J.5
  • 13
    • 79959452567 scopus 로고    scopus 로고
    • Serum 25-hydroxyvitamin D concentrations in relation to cardiometabolic risk factors and metabolic syndrome in postmenopausal women
    • Chacko S.A., Song Y., Manson J.E., Van Horn L., Eaton C., Martin L.W., et al. Serum 25-hydroxyvitamin D concentrations in relation to cardiometabolic risk factors and metabolic syndrome in postmenopausal women. Am J Clin Nutr 2011, 94:209-217.
    • (2011) Am J Clin Nutr , vol.94 , pp. 209-217
    • Chacko, S.A.1    Song, Y.2    Manson, J.E.3    Van Horn, L.4    Eaton, C.5    Martin, L.W.6
  • 14
    • 84861987922 scopus 로고    scopus 로고
    • Low serum 25-hydroxyvitamin D is associated with increased risk of the development of the metabolic syndrome at five years: results from a national, population-based prospective study (The Australian Diabetes, Obesity and Lifestyle Study: AusDiab)
    • Gagnon C., Lu Z.X., Magliano D.J., Dunstan D.W., Shaw J.E., Zimmet P.Z., et al. Low serum 25-hydroxyvitamin D is associated with increased risk of the development of the metabolic syndrome at five years: results from a national, population-based prospective study (The Australian Diabetes, Obesity and Lifestyle Study: AusDiab). J Clin Endocrinol Metab 2012, 97:1953-1961.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 1953-1961
    • Gagnon, C.1    Lu, Z.X.2    Magliano, D.J.3    Dunstan, D.W.4    Shaw, J.E.5    Zimmet, P.Z.6
  • 15
    • 67651180846 scopus 로고    scopus 로고
    • Effects of poor and short sleep on glucose metabolism and obesity risk
    • Spiegel K., Tasali E., Leproult R., Van Cauter E. Effects of poor and short sleep on glucose metabolism and obesity risk. Nat Rev Endocrinol 2009, 5:253-261.
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 253-261
    • Spiegel, K.1    Tasali, E.2    Leproult, R.3    Van Cauter, E.4
  • 16
    • 48749097017 scopus 로고    scopus 로고
    • A longitudinal study on the effect of shift work on weight gain in male Japanese workers
    • Suwazono Y., Dochi M., Sakata K., Okubo Y., Oishi M., Tanaka K., et al. A longitudinal study on the effect of shift work on weight gain in male Japanese workers. Obesity 2008, 16:1887-1893.
    • (2008) Obesity , vol.16 , pp. 1887-1893
    • Suwazono, Y.1    Dochi, M.2    Sakata, K.3    Okubo, Y.4    Oishi, M.5    Tanaka, K.6
  • 17
    • 33744971827 scopus 로고    scopus 로고
    • Sleep duration as a risk factor for the development of type 2 diabetes
    • Yaggi H.K., Araujo A.B., McKinlay J.B. Sleep duration as a risk factor for the development of type 2 diabetes. Diabetes Care 2006, 29:657-661.
    • (2006) Diabetes Care , vol.29 , pp. 657-661
    • Yaggi, H.K.1    Araujo, A.B.2    McKinlay, J.B.3
  • 18
    • 84855168949 scopus 로고    scopus 로고
    • Rotating night shift work and risk of type 2 diabetes: two prospective cohort studies in women
    • Pan A., Schernhammer E.S., Sun Q., Hu F.B. Rotating night shift work and risk of type 2 diabetes: two prospective cohort studies in women. PLoS Med 2011, 8:e1001141.
    • (2011) PLoS Med , vol.8 , pp. e1001141
    • Pan, A.1    Schernhammer, E.S.2    Sun, Q.3    Hu, F.B.4
  • 19
    • 84855166388 scopus 로고    scopus 로고
    • Shift work as a risk factor for future type 2 diabetes: evidence, mechanisms, implications, and future research directions
    • Kivimaki M., Batty G.D., Hublin C. Shift work as a risk factor for future type 2 diabetes: evidence, mechanisms, implications, and future research directions. PLoS Med 2011, 8:e1001138.
    • (2011) PLoS Med , vol.8 , pp. e1001138
    • Kivimaki, M.1    Batty, G.D.2    Hublin, C.3
  • 21
    • 55249103135 scopus 로고    scopus 로고
    • Shifts to and from daylight saving time and incidence of myocardial infarction
    • Janszky I., Ljung R. Shifts to and from daylight saving time and incidence of myocardial infarction. N Engl J Med 2008, 359:1966-1968.
    • (2008) N Engl J Med , vol.359 , pp. 1966-1968
    • Janszky, I.1    Ljung, R.2
  • 23
    • 84862008430 scopus 로고    scopus 로고
    • Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet
    • Hatori M., Vollmers C., Zarrinpar A., DiTacchio L., Bushong E.A., Gill S., et al. Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. Cell Metab 2012, 15:848-860.
    • (2012) Cell Metab , vol.15 , pp. 848-860
    • Hatori, M.1    Vollmers, C.2    Zarrinpar, A.3    DiTacchio, L.4    Bushong, E.A.5    Gill, S.6
  • 24
    • 84856097537 scopus 로고    scopus 로고
    • Circadian feeding drive of metabolic activity in adipose tissue and not hyperphagia triggers overweight in mice: is there a role of the pentose-phosphate pathway?
    • Stucchi P., Gil-Ortega M., Merino B., Guzman-Ruiz R., Cano V., Valladolid-Acebes I., et al. Circadian feeding drive of metabolic activity in adipose tissue and not hyperphagia triggers overweight in mice: is there a role of the pentose-phosphate pathway?. Endocrinology 2012, 153:690-699.
    • (2012) Endocrinology , vol.153 , pp. 690-699
    • Stucchi, P.1    Gil-Ortega, M.2    Merino, B.3    Guzman-Ruiz, R.4    Cano, V.5    Valladolid-Acebes, I.6
  • 25
    • 4344658781 scopus 로고    scopus 로고
    • Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity
    • Masaki T., Chiba S., Yasuda T., Noguchi H., Kakuma T., Watanabe T., et al. Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity. Diabetes 2004, 53:2250-2260.
    • (2004) Diabetes , vol.53 , pp. 2250-2260
    • Masaki, T.1    Chiba, S.2    Yasuda, T.3    Noguchi, H.4    Kakuma, T.5    Watanabe, T.6
  • 26
    • 77149173754 scopus 로고    scopus 로고
    • Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work
    • Salgado-Delgado R., Angeles-Castellanos M., Saderi N., Buijs R.M., Escobar C. Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work. Endocrinology 2010, 151:1019-1029.
    • (2010) Endocrinology , vol.151 , pp. 1019-1029
    • Salgado-Delgado, R.1    Angeles-Castellanos, M.2    Saderi, N.3    Buijs, R.M.4    Escobar, C.5
  • 28
    • 84863702634 scopus 로고    scopus 로고
    • The number of x chromosomes causes sex differences in adiposity in mice
    • Chen X., McClusky R., Chen J., Beaven S.W., Tontonoz P., Arnold A.P., et al. The number of x chromosomes causes sex differences in adiposity in mice. PLoS Gen 2012, 8:e1002709.
    • (2012) PLoS Gen , vol.8 , pp. e1002709
    • Chen, X.1    McClusky, R.2    Chen, J.3    Beaven, S.W.4    Tontonoz, P.5    Arnold, A.P.6
  • 29
    • 84864771866 scopus 로고    scopus 로고
    • Timed high-fat diet resets circadian metabolism and prevents obesity
    • Sherman H., Genzer Y., Cohen R., Chapnik N., Madar Z., Froy O. Timed high-fat diet resets circadian metabolism and prevents obesity. FASEB J 2012, 26:3493-3502.
    • (2012) FASEB J , vol.26 , pp. 3493-3502
    • Sherman, H.1    Genzer, Y.2    Cohen, R.3    Chapnik, N.4    Madar, Z.5    Froy, O.6
  • 31
    • 0023585752 scopus 로고
    • Chronobiological aspects of weight loss in obesity: effects of different meal timing regimens
    • Sensi S., Capani F. Chronobiological aspects of weight loss in obesity: effects of different meal timing regimens. Chronobiol Int 1987, 4:251-261.
    • (1987) Chronobiol Int , vol.4 , pp. 251-261
    • Sensi, S.1    Capani, F.2
  • 32
    • 63149163425 scopus 로고    scopus 로고
    • Adverse metabolic and cardiovascular consequences of circadian misalignment
    • Scheer F.A., Hilton M.F., Mantzoros C.S., Shea S.A. Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc Natl Acad Sci U S A 2009, 106:4453-4458.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 4453-4458
    • Scheer, F.A.1    Hilton, M.F.2    Mantzoros, C.S.3    Shea, S.A.4
  • 34
    • 80052899933 scopus 로고    scopus 로고
    • Genetics of circadian rhythms in mammalian model organisms
    • Lowrey P.L., Takahashi J.S. Genetics of circadian rhythms in mammalian model organisms. Adv Genet 2011, 74:175-230.
    • (2011) Adv Genet , vol.74 , pp. 175-230
    • Lowrey, P.L.1    Takahashi, J.S.2
  • 35
    • 84869036539 scopus 로고    scopus 로고
    • Circadian topology of metabolism
    • Bass J. Circadian topology of metabolism. Nature 2012, 491:348-356.
    • (2012) Nature , vol.491 , pp. 348-356
    • Bass, J.1
  • 36
    • 0038264052 scopus 로고    scopus 로고
    • Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice
    • Hattar S., Lucas R.J., Mrosovsky N., Thompson S., Douglas R.H., Hankins M.W., et al. Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice. Nature 2003, 424:76-81.
    • (2003) Nature , vol.424 , pp. 76-81
    • Hattar, S.1    Lucas, R.J.2    Mrosovsky, N.3    Thompson, S.4    Douglas, R.H.5    Hankins, M.W.6
  • 37
    • 84873287518 scopus 로고    scopus 로고
    • Blood-borne circadian signal stimulates daily oscillations in actin dynamics and SRF activity
    • Gerber A., Esnault C., Aubert G., Treisman R., Pralong F., Schibler U. Blood-borne circadian signal stimulates daily oscillations in actin dynamics and SRF activity. Cell 2013, 152:492-503.
    • (2013) Cell , vol.152 , pp. 492-503
    • Gerber, A.1    Esnault, C.2    Aubert, G.3    Treisman, R.4    Pralong, F.5    Schibler, U.6
  • 38
    • 48249084517 scopus 로고    scopus 로고
    • Suprachiasmatic nucleus clock time in the mammalian circadian system
    • Okamura H. Suprachiasmatic nucleus clock time in the mammalian circadian system. Cold Spring Harb Symp Quant Biol 2007, 72:551-556.
    • (2007) Cold Spring Harb Symp Quant Biol , vol.72 , pp. 551-556
    • Okamura, H.1
  • 39
    • 0037006807 scopus 로고    scopus 로고
    • Circadian programs of transcriptional activation, signaling, and protein turnover revealed by microarray analysis of mammalian cells
    • Duffield G.E., Best J.D., Meurers B.H., Bittner A., Loros J.J., Dunlap J.C. Circadian programs of transcriptional activation, signaling, and protein turnover revealed by microarray analysis of mammalian cells. Curr Biol 2002, 12:551-557.
    • (2002) Curr Biol , vol.12 , pp. 551-557
    • Duffield, G.E.1    Best, J.D.2    Meurers, B.H.3    Bittner, A.4    Loros, J.J.5    Dunlap, J.C.6
  • 41
  • 42
    • 18444414586 scopus 로고    scopus 로고
    • Coordinated transcription of key pathways in the mouse by the circadian clock
    • Panda S., Antoch M.P., Miller B.H., Su A.I., Schook A.B., Straume M., et al. Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 2002, 109:307-320.
    • (2002) Cell , vol.109 , pp. 307-320
    • Panda, S.1    Antoch, M.P.2    Miller, B.H.3    Su, A.I.4    Schook, A.B.5    Straume, M.6
  • 43
    • 54449085416 scopus 로고    scopus 로고
    • Physiological significance of a peripheral tissue circadian clock
    • Lamia K.A., Storch K.F., Weitz C.J. Physiological significance of a peripheral tissue circadian clock. Proc Natl Acad Sci U S A 2008, 105:15172-15177.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 15172-15177
    • Lamia, K.A.1    Storch, K.F.2    Weitz, C.J.3
  • 45
  • 46
    • 14044264801 scopus 로고    scopus 로고
    • BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis
    • Rudic R.D., McNamara P., Curtis A.M., Boston R.C., Panda S., Hogenesch J.B., et al. BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biol 2004, 2:e377.
    • (2004) PLoS Biol , vol.2 , pp. e377
    • Rudic, R.D.1    McNamara, P.2    Curtis, A.M.3    Boston, R.C.4    Panda, S.5    Hogenesch, J.B.6
  • 49
    • 84856019342 scopus 로고    scopus 로고
    • The nuclear receptor REV-ERBalpha mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines
    • Gibbs J.E., Blaikley J., Beesley S., Matthews L., Simpson K.D., Boyce S.H., et al. The nuclear receptor REV-ERBalpha mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines. Proc Natl Acad Sci U S A 2012, 109:582-587.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 582-587
    • Gibbs, J.E.1    Blaikley, J.2    Beesley, S.3    Matthews, L.4    Simpson, K.D.5    Boyce, S.H.6
  • 51
    • 20844461135 scopus 로고    scopus 로고
    • Obesity and metabolic syndrome in circadian Clock mutant mice
    • Turek F.W., Joshu C., Kohsaka A., Lin E., Ivanova G., McDearmon E., et al. Obesity and metabolic syndrome in circadian Clock mutant mice. Science 2005, 308:1043-1045.
    • (2005) Science , vol.308 , pp. 1043-1045
    • Turek, F.W.1    Joshu, C.2    Kohsaka, A.3    Lin, E.4    Ivanova, G.5    McDearmon, E.6
  • 52
    • 79953329154 scopus 로고    scopus 로고
    • Diurnal regulation of MTP and plasma triglyceride by CLOCK is mediated by SHP
    • Pan X., Zhang Y., Wang L., Hussain M.M. Diurnal regulation of MTP and plasma triglyceride by CLOCK is mediated by SHP. Cell Metab 2010, 12:174-186.
    • (2010) Cell Metab , vol.12 , pp. 174-186
    • Pan, X.1    Zhang, Y.2    Wang, L.3    Hussain, M.M.4
  • 53
    • 77954848215 scopus 로고    scopus 로고
    • Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes
    • Marcheva B., Ramsey K.M., Buhr E.D., Kobayashi Y., Su H., Ko C.H., et al. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature 2010, 466:627-631.
    • (2010) Nature , vol.466 , pp. 627-631
    • Marcheva, B.1    Ramsey, K.M.2    Buhr, E.D.3    Kobayashi, Y.4    Su, H.5    Ko, C.H.6
  • 56
    • 0033536228 scopus 로고    scopus 로고
    • The mPer2 gene encodes a functional component of the mammalian circadian clock
    • Zheng B., Larkin D.W., Albrecht U., Sun Z.S., Sage M., Eichele G., et al. The mPer2 gene encodes a functional component of the mammalian circadian clock. Nature 1999, 400:169-173.
    • (1999) Nature , vol.400 , pp. 169-173
    • Zheng, B.1    Larkin, D.W.2    Albrecht, U.3    Sun, Z.S.4    Sage, M.5    Eichele, G.6
  • 57
    • 77957821693 scopus 로고    scopus 로고
    • Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis
    • Zhang E.E., Liu Y., Dentin R., Pongsawakul P.Y., Liu A.C., Hirota T., et al. Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nat Med 2010, 16:1152-1156.
    • (2010) Nat Med , vol.16 , pp. 1152-1156
    • Zhang, E.E.1    Liu, Y.2    Dentin, R.3    Pongsawakul, P.Y.4    Liu, A.C.5    Hirota, T.6
  • 58
    • 84255206549 scopus 로고    scopus 로고
    • Cryptochromes mediate rhythmic repression of the glucocorticoid receptor
    • Lamia K.A., Papp S.J., Yu R.T., Barish G.D., Uhlenhaut N.H., Jonker J.W., et al. Cryptochromes mediate rhythmic repression of the glucocorticoid receptor. Nature 2011, 480:552-556.
    • (2011) Nature , vol.480 , pp. 552-556
    • Lamia, K.A.1    Papp, S.J.2    Yu, R.T.3    Barish, G.D.4    Uhlenhaut, N.H.5    Jonker, J.W.6
  • 60
    • 73849110168 scopus 로고    scopus 로고
    • Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6
    • Doi M., Takahashi Y., Komatsu R., Yamazaki F., Yamada H., Haraguchi S., et al. Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6. Nat Med 2010, 16:67-74.
    • (2010) Nat Med , vol.16 , pp. 67-74
    • Doi, M.1    Takahashi, Y.2    Komatsu, R.3    Yamazaki, F.4    Yamada, H.5    Haraguchi, S.6
  • 62
    • 2242456966 scopus 로고    scopus 로고
    • Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2
    • Vitaterna M.H., Selby C.P., Todo T., Niwa H., Thompson C., Fruechte E.M., et al. Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2. Proc Natl Acad Sci U S A 1999, 96:12114-12119.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12114-12119
    • Vitaterna, M.H.1    Selby, C.P.2    Todo, T.3    Niwa, H.4    Thompson, C.5    Fruechte, E.M.6
  • 63
    • 84870859377 scopus 로고    scopus 로고
    • Obesity in mice with adipocyte-specific deletion of clock component Arntl
    • Paschos G.K., Ibrahim S., Song W.L., Kunieda T., Grant G., Reyes T.M., et al. Obesity in mice with adipocyte-specific deletion of clock component Arntl. Nat Med 2012, 18:1768-1777.
    • (2012) Nat Med , vol.18 , pp. 1768-1777
    • Paschos, G.K.1    Ibrahim, S.2    Song, W.L.3    Kunieda, T.4    Grant, G.5    Reyes, T.M.6
  • 64
    • 79953323827 scopus 로고    scopus 로고
    • An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice
    • Sadacca L.A., Lamia K.A., deLemos A.S., Blum B., Weitz C.J. An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice. Diabetologia 2011, 54:120-124.
    • (2011) Diabetologia , vol.54 , pp. 120-124
    • Sadacca, L.A.1    Lamia, K.A.2    deLemos, A.S.3    Blum, B.4    Weitz, C.J.5
  • 65
    • 84879001061 scopus 로고    scopus 로고
    • Bmal1 and beta-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced beta-cell failure in mice
    • Lee J., Moulik M., Fang Z., Saha P., Zou F., Xu Y., et al. Bmal1 and beta-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced beta-cell failure in mice. Mol Cell Biol 2013, 33:2327-2338.
    • (2013) Mol Cell Biol , vol.33 , pp. 2327-2338
    • Lee, J.1    Moulik, M.2    Fang, Z.3    Saha, P.4    Zou, F.5    Xu, Y.6
  • 66
    • 84885573359 scopus 로고    scopus 로고
    • Circadian gene bmal1 regulates diurnal oscillations of Ly6Chi inflammatory monocytes
    • Nguyen K.D., Fentress S.J., Qiu Y., Yun K., Cox J.S., Chawla A. Circadian gene bmal1 regulates diurnal oscillations of Ly6Chi inflammatory monocytes. Science 2013, 341(6153):1483-1488.
    • (2013) Science , vol.341 , Issue.6153 , pp. 1483-1488
    • Nguyen, K.D.1    Fentress, S.J.2    Qiu, Y.3    Yun, K.4    Cox, J.S.5    Chawla, A.6
  • 67
  • 69
    • 84882255392 scopus 로고    scopus 로고
    • Rev-erb-alpha modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy
    • Woldt E., Sebti Y., Solt L.A., Duhem C., Lancel S., Eeckhoute J., et al. Rev-erb-alpha modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy. Nat Med 2013, 19:1039-1046.
    • (2013) Nat Med , vol.19 , pp. 1039-1046
    • Woldt, E.1    Sebti, Y.2    Solt, L.A.3    Duhem, C.4    Lancel, S.5    Eeckhoute, J.6
  • 70
    • 84860264490 scopus 로고    scopus 로고
    • Regulation of circadian behaviour and metabolism by REV-ERB-alpha and REV-ERB-beta
    • Cho H., Zhao X., Hatori M., Yu R.T., Barish G.D., Lam M.T., et al. Regulation of circadian behaviour and metabolism by REV-ERB-alpha and REV-ERB-beta. Nature 2012, 485:123-127.
    • (2012) Nature , vol.485 , pp. 123-127
    • Cho, H.1    Zhao, X.2    Hatori, M.3    Yu, R.T.4    Barish, G.D.5    Lam, M.T.6
  • 71
    • 33751565112 scopus 로고    scopus 로고
    • Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice
    • McDearmon E.L., Patel K.N., Ko C.H., Walisser J.A., Schook A.C., Chong J.L., et al. Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice. Science 2006, 314:1304-1308.
    • (2006) Science , vol.314 , pp. 1304-1308
    • McDearmon, E.L.1    Patel, K.N.2    Ko, C.H.3    Walisser, J.A.4    Schook, A.C.5    Chong, J.L.6
  • 73
    • 29344452934 scopus 로고    scopus 로고
    • Disrupted fat absorption attenuates obesity induced by a high-fat diet in Clock mutant mice
    • Oishi K., Atsumi G., Sugiyama S., Kodomari I., Kasamatsu M., Machida K., et al. Disrupted fat absorption attenuates obesity induced by a high-fat diet in Clock mutant mice. FEBS Lett 2006, 580:127-130.
    • (2006) FEBS Lett , vol.580 , pp. 127-130
    • Oishi, K.1    Atsumi, G.2    Sugiyama, S.3    Kodomari, I.4    Kasamatsu, M.5    Machida, K.6
  • 75
    • 42149170517 scopus 로고    scopus 로고
    • Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man
    • Scott E.M., Carter A.M., Grant P.J. Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man. Int J Obes 2008, 32:658-662.
    • (2008) Int J Obes , vol.32 , pp. 658-662
    • Scott, E.M.1    Carter, A.M.2    Grant, P.J.3
  • 76
    • 45749158901 scopus 로고    scopus 로고
    • Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity
    • Sookoian S., Gemma C., Gianotti T.F., Burgueno A., Castano G., Pirola C.J. Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity. Am J Clin Nutr 2008, 87:1606-1615.
    • (2008) Am J Clin Nutr , vol.87 , pp. 1606-1615
    • Sookoian, S.1    Gemma, C.2    Gianotti, T.F.3    Burgueno, A.4    Castano, G.5    Pirola, C.J.6
  • 77
    • 77953078014 scopus 로고    scopus 로고
    • PERIOD2 variants are associated with abdominal obesity, psycho-behavioral factors, and attrition in the dietary treatment of obesity
    • Garaulet M., Corbalan-Tutau M.D., Madrid J.A., Baraza J.C., Parnell L.D., Lee Y.C., et al. PERIOD2 variants are associated with abdominal obesity, psycho-behavioral factors, and attrition in the dietary treatment of obesity. J Am Diet Assoc 2010, 110:917-921.
    • (2010) J Am Diet Assoc , vol.110 , pp. 917-921
    • Garaulet, M.1    Corbalan-Tutau, M.D.2    Madrid, J.A.3    Baraza, J.C.4    Parnell, L.D.5    Lee, Y.C.6
  • 79
    • 13144293061 scopus 로고    scopus 로고
    • Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women
    • Licinio J., Negrao A.B., Mantzoros C., Kaklamani V., Wong M.L., Bongiorno P.B., et al. Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women. Proc Natl Acad Sci U S A 1998, 95:2541-2546.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 2541-2546
    • Licinio, J.1    Negrao, A.B.2    Mantzoros, C.3    Kaklamani, V.4    Wong, M.L.5    Bongiorno, P.B.6
  • 80
    • 24744470282 scopus 로고    scopus 로고
    • Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis
    • Shimba S., Ishii N., Ohta Y., Ohno T., Watabe Y., Hayashi M., et al. Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis. Proc Natl Acad Sci U S A 2005, 102:12071-12076.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 12071-12076
    • Shimba, S.1    Ishii, N.2    Ohta, Y.3    Ohno, T.4    Watabe, Y.5    Hayashi, M.6
  • 81
    • 84883388374 scopus 로고    scopus 로고
    • Circadian regulation of lipid mobilization in white adipose tissues
    • Shostak A., Meyer-Kovac J., Oster H. Circadian regulation of lipid mobilization in white adipose tissues. Diabetes 2013, 62:2195-2203.
    • (2013) Diabetes , vol.62 , pp. 2195-2203
    • Shostak, A.1    Meyer-Kovac, J.2    Oster, H.3
  • 82
    • 84862148508 scopus 로고    scopus 로고
    • Clock regulation of dietary lipid absorption
    • Hussain M.M., Pan X. Clock regulation of dietary lipid absorption. Curr Opin Clin Nutr Metab Care 2012, 15:336-341.
    • (2012) Curr Opin Clin Nutr Metab Care , vol.15 , pp. 336-341
    • Hussain, M.M.1    Pan, X.2
  • 83
    • 69849113069 scopus 로고    scopus 로고
    • Clock is important for food and circadian regulation of macronutrient absorption in mice
    • Pan X., Hussain M.M. Clock is important for food and circadian regulation of macronutrient absorption in mice. J Lipid Res 2009, 50:1800-1813.
    • (2009) J Lipid Res , vol.50 , pp. 1800-1813
    • Pan, X.1    Hussain, M.M.2
  • 84
    • 79952529158 scopus 로고    scopus 로고
    • A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism
    • Feng D., Liu T., Sun Z., Bugge A., Mullican S.E., Alenghat T., et al. A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism. Science 2011, 331:1315-1319.
    • (2011) Science , vol.331 , pp. 1315-1319
    • Feng, D.1    Liu, T.2    Sun, Z.3    Bugge, A.4    Mullican, S.E.5    Alenghat, T.6
  • 85
    • 84862025421 scopus 로고    scopus 로고
    • Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
    • Sun Z., Miller R.A., Patel R.T., Chen J., Dhir R., Wang H., et al. Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration. Nat Med 2012, 18:934-942.
    • (2012) Nat Med , vol.18 , pp. 934-942
    • Sun, Z.1    Miller, R.A.2    Patel, R.T.3    Chen, J.4    Dhir, R.5    Wang, H.6
  • 86
    • 84860291442 scopus 로고    scopus 로고
    • Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists
    • Solt L.A., Wang Y., Banerjee S., Hughes T., Kojetin D.J., Lundasen T., et al. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature 2012, 485:62-68.
    • (2012) Nature , vol.485 , pp. 62-68
    • Solt, L.A.1    Wang, Y.2    Banerjee, S.3    Hughes, T.4    Kojetin, D.J.5    Lundasen, T.6
  • 87
    • 0034992684 scopus 로고    scopus 로고
    • A daily rhythm in glucose tolerance: a role for the suprachiasmatic nucleus
    • la Fleur S.E., Kalsbeek A., Wortel J., Fekkes M.L., Buijs R.M. A daily rhythm in glucose tolerance: a role for the suprachiasmatic nucleus. Diabetes 2001, 50:1237-1243.
    • (2001) Diabetes , vol.50 , pp. 1237-1243
    • la Fleur, S.E.1    Kalsbeek, A.2    Wortel, J.3    Fekkes, M.L.4    Buijs, R.M.5
  • 89
    • 0029741066 scopus 로고    scopus 로고
    • Evidence for a circadian rhythm of insulin secretion
    • Boden G., Ruiz J., Urbain J.L., Chen X. Evidence for a circadian rhythm of insulin secretion. Am J Physiol 1996, 271(2 Pt 1):E246-E252.
    • (1996) Am J Physiol , vol.271 , Issue.2 , pp. E246-E252
    • Boden, G.1    Ruiz, J.2    Urbain, J.L.3    Chen, X.4
  • 90
    • 4544333235 scopus 로고    scopus 로고
    • Circadian rhythm of glucose uptake in cultures of skeletal muscle cells and adipocytes in Wistar-Kyoto, Wistar, Goto-Kakizaki, and spontaneously hypertensive rats
    • Feneberg R., Lemmer B. Circadian rhythm of glucose uptake in cultures of skeletal muscle cells and adipocytes in Wistar-Kyoto, Wistar, Goto-Kakizaki, and spontaneously hypertensive rats. Chronobiol Int 2004, 21:521-538.
    • (2004) Chronobiol Int , vol.21 , pp. 521-538
    • Feneberg, R.1    Lemmer, B.2
  • 92
    • 75749086085 scopus 로고    scopus 로고
    • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
    • Dupuis J., Langenberg C., Prokopenko I., Saxena R., Soranzo N., Jackson A.U., et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010, 42:105-116.
    • (2010) Nat Genet , vol.42 , pp. 105-116
    • Dupuis, J.1    Langenberg, C.2    Prokopenko, I.3    Saxena, R.4    Soranzo, N.5    Jackson, A.U.6
  • 94
    • 72749087085 scopus 로고    scopus 로고
    • CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acids
    • Garaulet M., Lee Y.C., Shen J., Parnell L.D., Arnett D.K., Tsai M.Y., et al. CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acids. Am J Clin Nutr 2009, 90:1466-1475.
    • (2009) Am J Clin Nutr , vol.90 , pp. 1466-1475
    • Garaulet, M.1    Lee, Y.C.2    Shen, J.3    Parnell, L.D.4    Arnett, D.K.5    Tsai, M.Y.6
  • 95
    • 84869747579 scopus 로고    scopus 로고
    • Immunity's fourth dimension: approaching the circadian-immune connection
    • Arjona A., Silver A.C., Walker W.E., Fikrig E. Immunity's fourth dimension: approaching the circadian-immune connection. Trends Immunol 2012, 33:607-612.
    • (2012) Trends Immunol , vol.33 , pp. 607-612
    • Arjona, A.1    Silver, A.C.2    Walker, W.E.3    Fikrig, E.4
  • 97
    • 84879694221 scopus 로고    scopus 로고
    • Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
    • Lam M.T., Cho H., Lesch H.P., Gosselin D., Heinz S., Tanaka-Oishi Y., et al. Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature 2013, 498:511-515.
    • (2013) Nature , vol.498 , pp. 511-515
    • Lam, M.T.1    Cho, H.2    Lesch, H.P.3    Gosselin, D.4    Heinz, S.5    Tanaka-Oishi, Y.6
  • 98
    • 84877721051 scopus 로고    scopus 로고
    • Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs
    • Mukherji A., Kobiita A., Ye T., Chambon P. Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs. Cell 2013, 153:812-827.
    • (2013) Cell , vol.153 , pp. 812-827
    • Mukherji, A.1    Kobiita, A.2    Ye, T.3    Chambon, P.4
  • 101
    • 78650878363 scopus 로고    scopus 로고
    • NF-kappaB, inflammation, and metabolic disease
    • Baker R.G., Hayden M.S., Ghosh S. NF-kappaB, inflammation, and metabolic disease. Cell Metab 2011, 13:11-22.
    • (2011) Cell Metab , vol.13 , pp. 11-22
    • Baker, R.G.1    Hayden, M.S.2    Ghosh, S.3
  • 102
    • 79151478555 scopus 로고    scopus 로고
    • Type 2 diabetes as an inflammatory disease
    • Donath M.Y., Shoelson S.E. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol 2011, 11:98-107.
    • (2011) Nat Rev Immunol , vol.11 , pp. 98-107
    • Donath, M.Y.1    Shoelson, S.E.2
  • 103
    • 52949096557 scopus 로고    scopus 로고
    • Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
    • Zhang X., Zhang G., Zhang H., Karin M., Bai H., Cai D. Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell 2008, 135:61-73.
    • (2008) Cell , vol.135 , pp. 61-73
    • Zhang, X.1    Zhang, G.2    Zhang, H.3    Karin, M.4    Bai, H.5    Cai, D.6
  • 104
    • 77949343027 scopus 로고    scopus 로고
    • The cardiomyocyte circadian clock: emerging roles in health and disease
    • Durgan D.J., Young M.E. The cardiomyocyte circadian clock: emerging roles in health and disease. Circ Res 2010, 106:647-658.
    • (2010) Circ Res , vol.106 , pp. 647-658
    • Durgan, D.J.1    Young, M.E.2
  • 106
    • 79957542251 scopus 로고    scopus 로고
    • Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus
    • Doi M., Ishida A., Miyake A., Sato M., Komatsu R., Yamazaki F., et al. Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus. Nat Commun 2011, 2:327.
    • (2011) Nat Commun , vol.2 , pp. 327
    • Doi, M.1    Ishida, A.2    Miyake, A.3    Sato, M.4    Komatsu, R.5    Yamazaki, F.6
  • 107
    • 39149108483 scopus 로고    scopus 로고
    • Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression
    • Bray M.S., Shaw C.A., Moore M.W., Garcia R.A., Zanquetta M.M., Durgan D.J., et al. Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression. Am J Physiology Heart Circ Physiol 2008, 294:H1036-H1047.
    • (2008) Am J Physiology Heart Circ Physiol , vol.294 , pp. H1036-H1047
    • Bray, M.S.1    Shaw, C.A.2    Moore, M.W.3    Garcia, R.A.4    Zanquetta, M.M.5    Durgan, D.J.6
  • 108
    • 56449089574 scopus 로고    scopus 로고
    • Vascular PPARgamma controls circadian variation in blood pressure and heart rate through Bmal1
    • Wang N., Yang G., Jia Z., Zhang H., Aoyagi T., Soodvilai S., et al. Vascular PPARgamma controls circadian variation in blood pressure and heart rate through Bmal1. Cell Metab 2008, 8:482-491.
    • (2008) Cell Metab , vol.8 , pp. 482-491
    • Wang, N.1    Yang, G.2    Jia, Z.3    Zhang, H.4    Aoyagi, T.5    Soodvilai, S.6
  • 109
    • 68849098451 scopus 로고    scopus 로고
    • The circadian clock protein Period 1 regulates expression of the renal epithelial sodium channel in mice
    • Gumz M.L., Stow L.R., Lynch I.J., Greenlee M.M., Rudin A., Cain B.D., et al. The circadian clock protein Period 1 regulates expression of the renal epithelial sodium channel in mice. J Clin Invest 2009, 119:2423-2434.
    • (2009) J Clin Invest , vol.119 , pp. 2423-2434
    • Gumz, M.L.1    Stow, L.R.2    Lynch, I.J.3    Greenlee, M.M.4    Rudin, A.5    Cain, B.D.6
  • 110
    • 84867715573 scopus 로고    scopus 로고
    • Increased superoxide and endothelial NO synthase uncoupling in blood vessels of Bmal1-knockout mice
    • Anea C.B., Cheng B., Sharma S., Kumar S., Caldwell R.W., Yao L., et al. Increased superoxide and endothelial NO synthase uncoupling in blood vessels of Bmal1-knockout mice. Circ Res 2012, 111:1157-1165.
    • (2012) Circ Res , vol.111 , pp. 1157-1165
    • Anea, C.B.1    Cheng, B.2    Sharma, S.3    Kumar, S.4    Caldwell, R.W.5    Yao, L.6
  • 111
    • 28344445503 scopus 로고    scopus 로고
    • PAI-1 and atherothrombosis
    • Vaughan D.E. PAI-1 and atherothrombosis. J Thromb Haemost 2005, 3:1879-1883.
    • (2005) J Thromb Haemost , vol.3 , pp. 1879-1883
    • Vaughan, D.E.1
  • 113
    • 84861040608 scopus 로고    scopus 로고
    • Thrombopoietin as biomarker and mediator of cardiovascular damage in critical diseases
    • Lupia E., Goffi A., Bosco O., Montrucchio G. Thrombopoietin as biomarker and mediator of cardiovascular damage in critical diseases. Mediators Inflamm 2012, 2012:3908-3992.
    • (2012) Mediators Inflamm , vol.2012 , pp. 3908-3992
    • Lupia, E.1    Goffi, A.2    Bosco, O.3    Montrucchio, G.4
  • 114
    • 77955055118 scopus 로고    scopus 로고
    • Effect of obesity on growth-related oncogene factor-alpha, thrombopoietin, and tissue inhibitor metalloproteinase-1 serum levels
    • Maury E., Brichard S.M., Pataky Z., Carpentier A., Golay A., Bobbioni-Harsch E. Effect of obesity on growth-related oncogene factor-alpha, thrombopoietin, and tissue inhibitor metalloproteinase-1 serum levels. Obesity 2010, 18:1503-1509.
    • (2010) Obesity , vol.18 , pp. 1503-1509
    • Maury, E.1    Brichard, S.M.2    Pataky, Z.3    Carpentier, A.4    Golay, A.5    Bobbioni-Harsch, E.6
  • 116
    • 35448972542 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes
    • Woon P.Y., Kaisaki P.J., Braganca J., Bihoreau M.T., Levy J.C., Farrall M., et al. Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes. Proc Natl Acad Sci U S A 2007, 104:14412-14417.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 14412-14417
    • Woon, P.Y.1    Kaisaki, P.J.2    Braganca, J.3    Bihoreau, M.T.4    Levy, J.C.5    Farrall, M.6
  • 118
    • 84875236078 scopus 로고    scopus 로고
    • Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome
    • Moller-Levet C.S., Archer S.N., Bucca G., Laing E.E., Slak A., Kabiljo R., et al. Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome. Proc Natl Acad Sci U S A 2013, 110:E1132-E1141.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. E1132-E1141
    • Moller-Levet, C.S.1    Archer, S.N.2    Bucca, G.3    Laing, E.E.4    Slak, A.5    Kabiljo, R.6
  • 121
    • 84878226490 scopus 로고    scopus 로고
    • Diurnal variation in vascular and metabolic function in diet-induced obesity: divergence of insulin resistance and loss of clock rhythm
    • Prasai M.J., Mughal R.S., Wheatcroft S.B., Kearney M.T., Grant P.J., Scott E.M. Diurnal variation in vascular and metabolic function in diet-induced obesity: divergence of insulin resistance and loss of clock rhythm. Diabetes 2013, 62:1981-1989.
    • (2013) Diabetes , vol.62 , pp. 1981-1989
    • Prasai, M.J.1    Mughal, R.S.2    Wheatcroft, S.B.3    Kearney, M.T.4    Grant, P.J.5    Scott, E.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.