Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice

Science

Volumn 314, Issue 5803, 2006, Pages 1304-1308

  McDearmon, Erin L ^a   Patel, Kush N ^a   Ko, Caroline H ^a,b   Walisser, Jacqueline A ^c   Schook, Andrew C ^a   Chong, Jason L ^a   Wilsbacher, Lisa D ^a   Song, Eun J ^a   Hong, Hee Kyung ^a   Bradfield, Christopher A ^c   Takahashi, Joseph S ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; GENETIC ENGINEERING; MUSCLE; PROTEINS; TENDONS; TISSUE;

CIRCADIAN RHYTHMICITY; MAMMALIAN CIRCADIAN PACEMAKER; MAMMALIAN CLOCK PROTEINS; TRANSGENIC MICE;

BIODIVERSITY;

PROTEIN BMAL1;

CIRCADIAN RHYTHM; GENE EXPRESSION; LONGEVITY; MAMMAL; PROTEIN; RODENT;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN; CALCIFICATION; CIRCADIAN RHYTHM; CONTROLLED STUDY; GENE EXPRESSION; LOCOMOTION; LONGEVITY; MOUSE; MUSCLE; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; TENDON; TISSUE SPECIFICITY; TRANSGENIC MOUSE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BODY WEIGHT; BRAIN; CALCINOSIS; CELL CYCLE PROTEINS; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CIRCADIAN RHYTHM; GENE EXPRESSION; LONGEVITY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR ACTIVITY; MUSCLE, SKELETAL; NUCLEAR PROTEINS; ORGAN SPECIFICITY; SUPRACHIASMATIC NUCLEUS; TENDONS; TRANSCRIPTION FACTORS;

MAMMALIA; MUS MUSCULUS;

EID: 33751565112     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1132430     Document Type: Article

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