-
1
-
-
50249100374
-
The meter of metabolism
-
Green, C.B., Takahashi, J.S. & Bass, J. The meter of metabolism. Cell 134, 728-742 (2008).
-
(2008)
Cell
, vol.134
, pp. 728-742
-
-
Green, C.B.1
Takahashi, J.S.2
Bass, J.3
-
2
-
-
0037194790
-
Coordination of circadian timing in mammals
-
Reppert, S.M. & Weaver, D.R. Coordination of circadian timing in mammals. Nature 418, 935-941 (2002).
-
(2002)
Nature
, vol.418
, pp. 935-941
-
-
Reppert, S.M.1
Weaver, D.R.2
-
3
-
-
77954848215
-
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes
-
Marcheva, B. et al. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature 466, 627-631 (2010).
-
(2010)
Nature
, vol.466
, pp. 627-631
-
-
Marcheva, B.1
-
4
-
-
54449085416
-
Physiological significance of a peripheral tissue circadian clock
-
Lamia, K.A., Storch, K.F. & Weitz, C.J. Physiological significance of a peripheral tissue circadian clock. Proc. Natl. Acad. Sci. USA 105, 15172-15177 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 15172-15177
-
-
Lamia, K.A.1
Storch, K.F.2
Weitz, C.J.3
-
5
-
-
29344452934
-
Disrupted fat absorption attenuates obesity induced by a high-fat diet in clock mutant mice
-
Oishi, K. et al. Disrupted fat absorption attenuates obesity induced by a high-fat diet in Clock mutant mice. FEBS Lett. 580, 127-130 (2006).
-
(2006)
FEBS Lett.
, vol.580
, pp. 127-130
-
-
Oishi, K.1
-
6
-
-
20844461135
-
Obesity and metabolic syndrome in circadian clock mutant mice
-
Turek, F.W. et al. Obesity and metabolic syndrome in circadian Clock mutant mice. Science 308, 1043-1045 (2005).
-
(2005)
Science
, vol.308
, pp. 1043-1045
-
-
Turek, F.W.1
-
7
-
-
14044264801
-
BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis
-
Rudic, R.D. et al. BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biol. 2, e377 (2004).
-
(2004)
PLoS Biol.
, vol.2
-
-
Rudic, R.D.1
-
8
-
-
36349023825
-
Study of shift work and risk of coronary events
-
Ellingsen, T., Bener, A. & Gehani, A.A. Study of shift work and risk of coronary events. J. R. Soc. Promot. Health 127, 265-267 (2007).
-
(2007)
J. R. Soc. Promot. Health
, vol.127
, pp. 265-267
-
-
Ellingsen, T.1
Bener, A.2
Gehani, A.A.3
-
9
-
-
0034771257
-
Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27, 485 people
-
Karlsson, B., Knutsson, A. & Lindahl, B. Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27, 485 people. Occup. Environ. Med. 58, 747-752 (2001).
-
(2001)
Occup. Environ. Med.
, vol.58
, pp. 747-752
-
-
Karlsson, B.1
Knutsson, A.2
Lindahl, B.3
-
10
-
-
67651180846
-
Effects of poor and short sleep on glucose metabolism and obesity risk
-
Spiegel, K., Tasali, E., Leproult, R. & Van Cauter, E. Effects of poor and short sleep on glucose metabolism and obesity risk. Nat. Rev. Endocrinol. 5, 253-261 (2009).
-
(2009)
Nat. Rev. Endocrinol.
, vol.5
, pp. 253-261
-
-
Spiegel, K.1
Tasali, E.2
Leproult, R.3
Van Cauter, E.4
-
11
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
Ahima, R.S. et al. Role of leptin in the neuroendocrine response to fasting. Nature 382, 250-252 (1996).
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
-
12
-
-
0035942777
-
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
-
Cowley, M.A. et al. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 411, 480-484 (2001).
-
(2001)
Nature
, vol.411
, pp. 480-484
-
-
Cowley, M.A.1
-
13
-
-
0032915413
-
Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting
-
Mizuno, T.M. & Mobbs, C.V. Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting. Endocrinology 140, 814-817 (1999).
-
(1999)
Endocrinology
, vol.140
, pp. 814-817
-
-
Mizuno, T.M.1
Mobbs, C.V.2
-
14
-
-
16244388931
-
Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis
-
Lam, T.K. et al. Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis. Nat. Med. 11, 320-327 (2005).
-
(2005)
Nat. Med.
, vol.11
, pp. 320-327
-
-
Lam, T.K.1
-
15
-
-
33645531123
-
Restoration of hypothalamic lipid sensing Normalizes energy and glucose homeostasis in overfed rats
-
Pocai, A. et al. Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats. J. Clin. Invest. 116, 1081-1091 (2006).
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1081-1091
-
-
Pocai, A.1
-
16
-
-
84855971481
-
Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity
-
Cintra, D.E. et al. Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity. PLoS ONE 7, e30571 (2012).
-
(2012)
PLoS ONE
, vol.7
-
-
Cintra, D.E.1
-
17
-
-
0034704203
-
Mop3 is an essential component of the master circadian pacemaker in mammals
-
Bunger, M.K. et al. Mop3 is an essential component of the master circadian pacemaker in mammals. Cell 103, 1009-1017 (2000).
-
(2000)
Cell
, vol.103
, pp. 1009-1017
-
-
Bunger, M.K.1
-
18
-
-
17044396029
-
Progressive arthropathy in mice with a targeted disruption of the mop3/Bmal-1 locus
-
Bunger, M.K. et al. Progressive arthropathy in mice with a targeted disruption of the Mop3/Bmal-1 locus. Genesis 41, 122-132 (2005).
-
(2005)
Genesis
, vol.41
, pp. 122-132
-
-
Bunger, M.K.1
-
19
-
-
33746191906
-
Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock
-
Kondratov, R.V., Kondratova, A.A., Gorbacheva, V.Y., Vykhovanets, O.V. & Antoch, M.P. Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock. Genes Dev. 20, 1868-1873 (2006).
-
(2006)
Genes Dev.
, vol.20
, pp. 1868-1873
-
-
Kondratov, R.V.1
Kondratova, A.A.2
Gorbacheva, V.Y.3
Vykhovanets, O.V.4
Antoch, M.P.5
-
20
-
-
42449107875
-
Genetic components of the circadian clock regulate thrombogenesis in vivo
-
Westgate, E.J. et al. Genetic components of the circadian clock regulate thrombogenesis in vivo. Circulation 117, 2087-2095 (2008).
-
(2008)
Circulation
, vol.117
, pp. 2087-2095
-
-
Westgate, E.J.1
-
21
-
-
9144229185
-
Adipose-specific peroxisome proliferator-activated receptor y knockout causes insulin resistance in fat and liver but not in muscle
-
He, W. et al. Adipose-specific peroxisome proliferator-activated receptor y knockout causes insulin resistance in fat and liver but not in muscle. Proc. Natl. Acad. Sci. USA 100, 15712-15717 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15712-15717
-
-
He, W.1
-
22
-
-
0033177995
-
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
-
Clausen, B.E., Burkhardt, C, Reith, W., Renkawitz, R. & Forster, I. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8, 265-277 (1999).
-
(1999)
Transgenic Res.
, vol.8
, pp. 265-277
-
-
Clausen, B.E.1
Burkhardt, C.2
Reith, W.3
Renkawitz, R.4
Forster, I.5
-
23
-
-
0037426839
-
Rhythmic histone acetylation underlies transcription in the Mammalian circadian clock
-
Etchegaray, J.P., Lee, C, Wade, P.A. & Reppert, S.M. Rhythmic histone acetylation underlies transcription in the mammalian circadian clock. Nature 421, 177-182 (2003).
-
(2003)
Nature
, vol.421
, pp. 177-182
-
-
Etchegaray, J.P.1
Lee, C.2
Wade, P.A.3
Reppert, S.M.4
-
24
-
-
13944254430
-
System-level identification of transcriptional circuits underlying Mammalian circadian clocks
-
Ueda, H.R. et al. System-level identification of transcriptional circuits underlying mammalian circadian clocks. Nat. Genet. 37, 187-192 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 187-192
-
-
Ueda, H.R.1
-
25
-
-
78149245166
-
Characterization of the core Mammalian clock component, NPAS2, as a REV-ERBα/RORα target gene
-
Crumbley, C, Wang, Y., Kojetin, D.J. & Burris, T.P. Characterization of the core mammalian clock component, NPAS2, as a REV-ERBα/RORα target gene. J. Biol. Chem. 285, 35386-35392 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 35386-35392
-
-
Crumbley, C.1
Wang, Y.2
Kojetin, D.J.3
Burris, T.P.4
-
26
-
-
33646130147
-
A clock shock: Mouse CLOCK is not required for circadian oscillator function
-
Debruyne, J.P. et al. A clock shock: mouse CLOCK is not required for circadian oscillator function. Neuron 50, 465-477 (2006).
-
(2006)
Neuron
, vol.50
, pp. 465-477
-
-
Debruyne, J.P.1
-
27
-
-
33847632469
-
Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation
-
Miller, B.H. et al. Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation. Proc. Natl. Acad. Sci. USA 104, 3342-3347 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 3342-3347
-
-
Miller, B.H.1
-
28
-
-
33846944676
-
System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock
-
Kornmann, B., Schaad, O., Bujard, H., Takahashi, J.S. & Schibler, U. System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock. PLoS Biol. 5, e34 (2007).
-
(2007)
PLoS Biol.
, vol.5
-
-
Kornmann, B.1
Schaad, O.2
Bujard, H.3
Takahashi, J.S.4
Schibler, U.5
-
29
-
-
79952155359
-
Transcriptional control of adipose lipid handling by IRF4
-
Eguchi, J. et al. Transcriptional control of adipose lipid handling by IRF4. Cell Metab. 13, 249-259 (2011).
-
(2011)
Cell Metab.
, vol.13
, pp. 249-259
-
-
Eguchi, J.1
-
30
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei, M. et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat. Med. 1, 1155-1161 (1995).
-
(1995)
Nat. Med.
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
-
31
-
-
0033931981
-
Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
-
El-Haschimi, K., Pierroz, D.D., Hileman, S.M., Bjorbaek, C. & Flier, J.S. Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. J. Clin. Invest. 105, 1827-1832 (2000).
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1827-1832
-
-
El-Haschimi, K.1
Pierroz, D.D.2
Hileman, S.M.3
Bjorbaek, C.4
Flier, J.S.5
-
32
-
-
0030047905
-
Binge eating disorder and the night-eating syndrome
-
Stunkard, A. et al. Binge eating disorder and the night-eating syndrome. Int. J. Obes. Relat. Metab. Disord. 20, 1-6 (1996).
-
(1996)
Int. J. Obes. Relat. Metab. Disord.
, vol.20
, pp. 1-6
-
-
Stunkard, A.1
-
33
-
-
0032510778
-
The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors
-
Hogenesch, J.B., Gu, Y.Z., Jain, S. & Bradfeld, C.A. The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors. Proc. Natl. Acad. Sci. USA 95, 5474-5479 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5474-5479
-
-
Hogenesch, J.B.1
Gu, Y.Z.2
Jain, S.3
Bradfeld, C.A.4
-
34
-
-
77956165390
-
GPR120 is an omega-3 fatty acid receptor mediating potent antiinflammatory and insulin-sensitizing effects
-
Oh, D.Y. et al. GPR120 is an omega-3 fatty acid receptor mediating potent antiinflammatory and insulin-sensitizing effects. Cell 142, 687-698 (2010).
-
(2010)
Cell
, vol.142
, pp. 687-698
-
-
Oh, D.Y.1
-
35
-
-
77249149984
-
Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditure
-
Wei, E. et al. Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditure. Cell Metab. 11, 183-193 (2010).
-
(2010)
Cell Metab.
, vol.11
, pp. 183-193
-
-
Wei, E.1
-
36
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
Minokoshi, Y. et al. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 428, 569-574 (2004).
-
(2004)
Nature
, vol.428
, pp. 569-574
-
-
Minokoshi, Y.1
-
37
-
-
77956827261
-
IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKβ and ER stress inhibition
-
Ropelle, E.R. et al. IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKβ and ER stress inhibition. PLoS Biol. 8, e1000465 (2010).
-
(2010)
PLoS Biol.
, vol.8
-
-
Ropelle, E.R.1
-
38
-
-
77954995403
-
Adrenal glucocorticoids have a key role in circadian resynchronization in a mouse model of jet lag
-
Kiessling, S., Eichele, G. & Oster, H. Adrenal glucocorticoids have a key role in circadian resynchronization in a mouse model of jet lag. J. Clin. Invest. 120, 2600-2609 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2600-2609
-
-
Kiessling, S.1
Eichele, G.2
Oster, H.3
-
39
-
-
79959791037
-
Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans
-
Pietiläinen, K.H. et al. Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans. PLoS Biol. 9, e1000623 (2011).
-
(2011)
PLoS Biol.
, vol.9
-
-
Pietiläinen, K.H.1
-
40
-
-
70350574819
-
Circadian timing of food intake contributes to weight gain
-
Arble, D.M., Bass, J., Laposky, A.D., Vitaterna, M.H. & Turek, F.W. Circadian timing of food intake contributes to weight gain. Obesity (Silver Spring) 17, 2100-2102 (2009).
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 2100-2102
-
-
Arble, D.M.1
Bass, J.2
Laposky, A.D.3
Vitaterna, M.H.4
Turek, F.W.5
-
41
-
-
84856097537
-
Circadian feeding drive of metabolic activity in adipose tissue and not hyperphagia triggers overweight in mice: Is there a role of the pentose-phosphate pathway?
-
Stucchi, P. et al. Circadian feeding drive of metabolic activity in adipose tissue and not hyperphagia triggers overweight in mice: is there a role of the pentose-phosphate pathway? Endocrinology 153, 690-699 (2012).
-
(2012)
Endocrinology
, vol.153
, pp. 690-699
-
-
Stucchi, P.1
-
42
-
-
84862008430
-
Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet
-
Hatori, M. et al. Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. Cell Metab. 15, 848-860 (2012).
-
(2012)
Cell Metab.
, vol.15
, pp. 848-860
-
-
Hatori, M.1
-
43
-
-
4344658781
-
Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity
-
Masaki, T. et al. Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity. Diabetes 53, 2250-2260 (2004).
-
(2004)
Diabetes
, vol.53
, pp. 2250-2260
-
-
Masaki, T.1
-
44
-
-
77149173754
-
Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work
-
Salgado-Delgado, R., Angeles-Castellanos, M., Saderi, N., Buijs, R.M. & Escobar, C. Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work. Endocrinology 151, 1019-1029 (2010).
-
(2010)
Endocrinology
, vol.151
, pp. 1019-1029
-
-
Salgado-Delgado, R.1
Angeles-Castellanos, M.2
Saderi, N.3
Buijs, R.M.4
Escobar, C.5
-
45
-
-
78649864368
-
Light at night increases body mass by shifting the time of food intake
-
Fonken, L.K. et al. Light at night increases body mass by shifting the time of food intake. Proc. Natl. Acad. Sci. USA 107, 18664-18669 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 18664-18669
-
-
Fonken, L.K.1
-
46
-
-
63149163425
-
Adverse metabolic and cardiovascular consequences of circadian misalignment
-
Scheer, F.A., Hilton, M.F., Mantzoros, C.S. & Shea, S.A. Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc. Natl. Acad. Sci. USA 106, 4453-4458 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 4453-4458
-
-
Scheer, F.A.1
Hilton, M.F.2
Mantzoros, C.S.3
Shea, S.A.4
-
47
-
-
0037707799
-
Categorically distinct acute stressors elicit dissimilar transcriptional profiles in the paraventricular nucleus of the hypothalamus
-
Reyes, T.M., Walker, J.R., DeCino, C., Hogenesch, J.B. & Sawchenko, P.E. Categorically distinct acute stressors elicit dissimilar transcriptional profiles in the paraventricular nucleus of the hypothalamus. J. Neurosci. 23, 5607-5616 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 5607-5616
-
-
Reyes, T.M.1
Walker, J.R.2
DeCino, C.3
Hogenesch, J.B.4
Sawchenko, P.E.5
-
48
-
-
78650738607
-
Increased hepatic oxidative metabolism distinguishes the action of peroxisome proliferator-activated receptor δ; from peroxisome proliferator-activated receptor γ in the ob/ob mouse
-
Roberts, L.D. et al. Increased hepatic oxidative metabolism distinguishes the action of peroxisome proliferator-activated receptor δ; from peroxisome proliferator-activated receptor γ in the ob/ob mouse. Genome Med. 1, 115 (2009).
-
(2009)
Genome Med.
, vol.1
, pp. 115
-
-
Roberts, L.D.1
-
49
-
-
12344280017
-
Summaries of affymetrix GeneChip probe level data
-
Irizarry, R.A. et al. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res. 31, e15 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Irizarry, R.A.1
-
50
-
-
19344366781
-
Jr. A practical false discovery rate approach to identifying patterns of differential expression in microarray data
-
Grant, G.R., Liu, J. & Stoeckert, C.J. Jr. A practical false discovery rate approach to identifying patterns of differential expression in microarray data. Bioinformatics 21, 2684-2690 (2005).
-
(2005)
Bioinformatics
, vol.21
, pp. 2684-2690
-
-
Grant, G.R.1
Liu, J.2
Stoeckert, C.J.3
|