The UDP-glucuronosyltransferases of the blood-brain barrier: Their role in drug metabolism and detoxication

Frontiers in Cellular Neuroscience

Volumn 8, Issue October, 2014, Pages

  Ouzzine, Mohamed ^a   Gulberti, Sandrine ^a   Ramalanjaona, Nick ^a   Magdalou, Jacques ^a   Fournel Gigleux, Sylvie ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

Author keywords

Blood brain barrier; Detoxication barrier; Drug glucuronidation; Glucuronidation of endogenous compounds; UDP glucuronosyltransferases

Indexed keywords

ALCOHOL; BILIRUBIN; CATECHOL METHYLTRANSFERASE; CYTOCHROME P450; DOPAMINE; GLUCURONIC ACID; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A; GLUCURONOSYLTRANSFERASE 2A; GLUCURONOSYLTRANSFERASE 2B; GLUCURONOSYLTRANSFERASE 3A; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INTERLEUKIN 6; MESSENGER RNA; MORPHINE; MORPHINE 6 GLUCURONIDE; NEUROTRANSMITTER; NITRIC OXIDE; POLYCHLORINATED BIPHENYL; RESVERATROL; SEROTONIN; STEROID; SULFOTRANSFERASE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN FUNCTION; BRAIN TOXICITY; DRUG DETOXIFICATION; DRUG GLUCURONIDATION; DRUG METABOLISM; DRUG TRANSFORMATION; ENDOTHELIUM CELL; ENZYME SPECIFICITY; HUMAN; HYPOPHYSIS; LIVER; METABOLITE; NONHUMAN; OLFACTORY BULB; OLFACTORY EPITHELIUM; PINEAL BODY; PROTEIN EXPRESSION; TOXIC INHALATION;

EID: 84908375042     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2014.00349     Document Type: Article

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