In vitro morphine metabolism by rat microglia

Neuropharmacology

Volumn 75, Issue , 2013, Pages 391-398

  Togna, Anna Rita ^a   Antonilli, Letizia ^a   Dovizio, Melania ^b   Salemme, Adele ^a   De Carolis, Lorenza ^a   Togna, Giuseppina I ^a   Patrignani, Paola ^b   Nencini, Paolo ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

Author keywords

Microglia; Morphine 3 glucuronide; Morphine 6 glucuronide; Rat; UGT

Indexed keywords

GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A6; GLUCURONOSYLTRANSFERASE 1A7; GLUCURONOSYLTRANSFERASE 2B1; MESSENGER RNA; MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE; NITRITE; PROSTAGLANDIN E2; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; AIF1 PROTEIN, RAT; CALCIUM BINDING PROTEIN; MORPHINE DERIVATIVE; MORPHINE-3-GLUCURONIDE; MORPHINE-6-GLUCURONIDE; NARCOTIC AGENT;

ANIMAL CELL; ARTICLE; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EXPOSURE; DRUG GLUCURONIDATION; DRUG SYNTHESIS; DRUG TRANSFORMATION; EXTRACELLULAR SPACE; GENE EXPRESSION REGULATION; IN VITRO STUDY; INCUBATION TIME; INTRACELLULAR SPACE; LIMIT OF DETECTION; MICROGLIAL CELL CULTURE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION; ANIMAL; BRAIN CORTEX; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; GENETICS; LIQUID CHROMATOGRAPHY; METABOLISM; MICROGLIA; TANDEM MASS SPECTROMETRY; TIME; UGT;

MICROGLIA; MORPHINE-3-GLUCURONIDE; MORPHINE-6-GLUCURONIDE; RAT; UGT;

ANIMALS; ANIMALS, NEWBORN; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; CEREBRAL CORTEX; CHROMATOGRAPHY, LIQUID; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCURONOSYLTRANSFERASE; MICROFILAMENT PROTEINS; MICROGLIA; MORPHINE; MORPHINE DERIVATIVES; NARCOTICS; NITRITES; RATS; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 84884192137     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.08.019     Document Type: Article

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