Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDP-glucuronosyltransferases (UGTs): evidence for the functionally active UGT in P450-UGT complex.

Drug metabolism and pharmacokinetics

Volumn 22, Issue 5, 2007, Pages 367-376

  Ishii, Yuji ^a   Iwanaga, Megumi ^a   Nishimura, Yoshio ^a   Takeda, Shuso ^a   Ikushiro, Shin Ichi ^a   Nagata, Kiyoshi ^a   Yamazoe, Yasushi ^a   Mackenzie, Peter I ^a   Yamada, Hideyuki ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4-METHYLUMBELLIFERONE; CYP1A2 PROTEIN, RAT; CYP2C11 PROTEIN, RAT; CYP2C13 PROTEIN, RAT; CYP3A2 PROTEIN, RAT; CYTOCHROME P450; CYTOCHROME P450 1A2; DRUG DERIVATIVE; GLUCURONOSYLTRANSFERASE; HYMECROMONE; MEMBRANE PROTEIN; MULTIENZYME COMPLEX; STEROID 16 BETA HYDROXYLASE; STEROID 16-BETA-HYDROXYLASE; STEROID 16ALPHA MONOOXYGENASE; STEROID MONOOXYGENASE; UDP GLUCURONOSYLTRANSFERASE, UGT1A7; UDP-GLUCURONOSYLTRANSFERASE, UGT1A7; UGT1A1 PROTEIN, RAT; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ANIMAL; ARTICLE; ENZYME SPECIFICITY; ENZYMOLOGY; IMMUNOPRECIPITATION; LIVER MICROSOME; MALE; METABOLISM; PROTEIN BINDING; RAT; WISTAR RAT;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; GLUCURONOSYLTRANSFERASE; HYMECROMONE; IMMUNOPRECIPITATION; MALE; MEMBRANE PROTEINS; MICROSOMES, LIVER; MULTIENZYME COMPLEXES; PROTEIN BINDING; RATS; RATS, WISTAR; STEROID 16-ALPHA-HYDROXYLASE; STEROID HYDROXYLASES; SUBSTRATE SPECIFICITY;

EID: 38449093974     PISSN: 13474367     EISSN: None     Source Type: Journal    
DOI: 10.2133/dmpk.22.367     Document Type: Article

References (0)