Glucuronidation in the chimpanzee (Pan troglodytes): Studies with acetaminophen, oestradiol and morphine

Xenobiotica

Volumn 36, Issue 12, 2006, Pages 1178-1190

  Wong, H ^a   Grace Jr , J E ^e   Wright, M R ^b   Browning, M R ^e   Grossman, S J ^e   Bai, S A ^c   Christ, D D ^d  

^a GENENTECH INC   (United States)

^b Gilead   (United States)

^c CENTOCOR INC   (United States)

^d SNC Partners LLC   (United States)

^e MS 86 ^*

Author keywords

Chimpanzees; Enzyme kinetics; Glucuronidation; Human; Pharmacokinetics; Sulphate conjugation

Indexed keywords

ESTRADIOL; ESTRADIOL 17 GLUCURONIDE; ESTRADIOL 3 GLUCURONIDE; ESTRADIOL DERIVATIVE; MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE; PARACETAMOL; PARACETAMOL GLUCURONIDE; PARACETAMOL SULFATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG GLUCURONIDATION; DRUG HALF LIFE; ENZYME KINETICS; EXPERIMENTAL ANIMAL; HUMAN; HUMAN CELL; HUMAN VERSUS ANIMAL COMPARISON; LIVER MICROSOME; MALE; NONHUMAN; PAN TROGLODYTES; SINGLE DRUG DOSE; URINARY EXCRETION; WESTERN BLOTTING;

ACETAMINOPHEN; ADMINISTRATION, ORAL; ANIMALS; ESTRADIOL; FEMALE; GLUCURONIDES; HUMANS; MALE; MICROSOMES, LIVER; MODELS, ANIMAL; MORPHINE; PAN TROGLODYTES; SPECIES SPECIFICITY;

ANIMALIA; PAN; PAN TROGLODYTES;

EID: 33845620884     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.1080/00498250600911028     Document Type: Article

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