Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain

Brain, Behavior, and Immunity

Volumn 30, Issue , 2013, Pages 24-32

  Lewis, Susannah S ^a   Hutchinson, Mark R ^b   Zhang, Yingning ^a   Hund, Dana K ^a   Maier, Steven F ^a   Rice, Kenner C ^c   Watkins, Linda R ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

(+) Naloxone; Dextro naloxone; Ethanol; Ethyl glucuronide; Glucoronidation; Glucuronic acid; Metabolite; TLR4

Indexed keywords

ETHYL GLUCURONIDE; GLUCURONIC ACID; LIPOPOLYSACCHARIDE; MORPHINE 3 GLUCURONIDE; NALOXONE; TOLL LIKE RECEPTOR 4;

ALCOHOL WITHDRAWAL; ALLODYNIA; ANIMAL EXPERIMENT; ARTICLE; COMPUTER MODEL; ENZYME ACTIVATION; HANGOVER; HEADACHE; HYPERALGESIA; MALE; MOLECULAR DOCKING; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RHODOBACTER SPHAEROIDES; SIMULATION;

ANIMALS; ETHANOL; GLUCURONIC ACID; GLUCURONIDES; HEK293 CELLS; HUMANS; HYPERALGESIA; MALE; PAIN; PAIN MEASUREMENT; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84876871641     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2013.01.005     Document Type: Article

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