In situ gelling pH- and temperature-sensitive biodegradable block copolymer hydrogels for drug delivery

Journal of Controlled Release

Volumn 193, Issue , 2014, Pages 214-227

  Singh, Narendra K ^a   Lee, Doo Sung ^a  

^a Sungkyunkwan University   (South Korea)

Author keywords

Drug delivery; Injectable hydrogel; Stimuli sensitive

Indexed keywords

BIODEGRADABLE BLOCK COPOLYMERS; IN-SITU-GELLING; INJECTABLE HYDROGELS; STIMULI-SENSITIVE; TEMPERATURE-SENSITIVE;

DRUG DELIVERY;

BIODEGRADABLE BLOCK COPOLYMER HYDROGEL; COPOLYMER; INJECTABLE BLOCK COPOLYMER HYDROGEL; POLYESTER; POLYPEPTIDE; UNCLASSIFIED DRUG; BIOMATERIAL; DRUG CARRIER; HUMAN GROWTH HORMONE; HYDROGEL; INSULIN; MACROGOL DERIVATIVE; POLYETHYLENE GLYCOL-POLYLACTIDE-POLYETHYLENE GLYCOL; RECOMBINANT PROTEIN;

AQUEOUS SOLUTION; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED DRUG RELEASE; DEGRADATION KINETICS; DRUG DELIVERY SYSTEM; GELATION; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR WEIGHT; NONHUMAN; PH; PHASE TRANSITION; POLYMERIZATION; REVIEW; RING OPENING; TEMPERATURE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG FORMULATION; DRUG RELEASE; HUMAN; TISSUE ADHESION;

ANIMALS; BIOCOMPATIBLE MATERIALS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG LIBERATION; HUMAN GROWTH HORMONE; HUMANS; HYDROGELS; HYDROGEN-ION CONCENTRATION; INSULIN; MOLECULAR STRUCTURE; PHASE TRANSITION; POLYESTERS; POLYETHYLENE GLYCOLS; RECOMBINANT PROTEINS; TEMPERATURE; TISSUE ADHESIONS;

EID: 84908291543     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.04.056     Document Type: Review

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122. K. Dayananda, C. He, D.K. Park, T.G. Park, and D.S. Lee pH- and temperature-sensitive multiblock copolymer hydrogels composed of poly(ethylene glycol) and poly(amino urethane) Polymer 49 2008 4968 4973
123. C.T. Huynh, M.K. Nguyen, D.P. Huynh, S.W. Kim, and D.S. Lee pH/temperature-sensitive 4-arm poly(ethylene glycol)-poly(amino urethane) copolymer hydrogels Polymer 51 2010 3843 3850
124. C.T. Huynh, Q.V. Nguyen, S.W. Kang, and D.S. Lee Synthesis and characterization of poly(amino urea urethane)-based block copolymer and its potential application as injectable pH/temperature-sensitive hydrogel for protein carrier Polymer 53 2012 4069 4075
125. M.K. Nguyen, D.K. Park, and D.S. Lee Injectable poly(amidoamine)-poly(ethylene glycol)-poly(amidoamine) triblock copolymer hydrogel with dual sensitivities: pH and temperature Biomacromolecules 10 2009 728 731
126. M.K. Nguyen, and D.S. Lee Bioadhesive PAA-PEG-PAA triblock copolymer hydrogels for drug delivery in oral cavity Macromol. Res. 18 2010 284 288
127. C.T. Huynh, M.K. Nguyen, J.H. Kim, S.W. Kang, B.S. Kim, and D.S. Lee Sustained delivery of doxorubicin using biodegradable pH/temperature-sensitive poly(ethylene glycol)-poly(b-amino ester urethane) multiblock copolymer hydrogels Soft Matter 7 2011 4974 4982
128. C.T. Huynh, S.W. Kang, Y. Li, B.S. Kim, and D.S. Lee Controlled release of human growth hormone from a biodegradable pH/temperature-sensitive hydrogel system Soft Matter 7 2011 8984 8990
129. C.T. Huynh, M.K. Nguyen, and D.S. Lee Dually cationic and anionic pH/temperature-sensitive injectable hydrogels and potential application as a protein carrier Chem. Commun. 48 2012 10951 10953
130. M.K. Nguyen, and D.S. Lee Oligo(amidoamine)s hydrogels with tunable gel properties Chem. Commun. 46 2010 3583 3585
131. C.T. Huynh, M.K. Nguyen, and D.S. Lee Biodegradable pH/temperature-sensitive oligo(β-amino ester urethane)hydrogels for controlled release of doxorubicin Acta Biomater. 7 2011 3123 3130
132. M.K. Nguyen, C.T. Huynh, G.H. Gao, Ji Hyun Kim, D.P. Huynh, S.Y. Chae, K.C. Lee, and D.S. Lee Biodegradable oligo(amidoamine/β-amino ester) hydrogels for controlled insulin delivery Soft Matter 7 2011 2994 3001