The use of de-differentiated chondrocytes delivered by a heparin-based hydrogel to regenerate cartilage in partial-thickness defects

Biomaterials

Volumn 32, Issue 31, 2011, Pages 7883-7896

  Kim, Mihye ^a   Kim, Se Eun ^b   Kang, Seong Soo ^b   Kim, Young Ha ^a   Tae, Giyoong ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Chonnam National University   (South Korea)

Author keywords

Chondrocytes; De differentiation; Heparin; Hydrogel; Partial thickness defect

Indexed keywords

AUTOLOGOUS CHONDROCYTE TRANSPLANTATIONS; BONE INJURY; CARTILAGE DEFECTS; CARTILAGE FORMATION; CARTILAGE REGENERATION; CARTILAGE REPAIR; CHONDROCYTES; CHONDROGENESIS; CHONDROGENIC; CHONDROGENIC PHENOTYPES; CONTROL DEFECTS; CULTURE CONDITIONS; DE-DIFFERENTIATION; ENDOGENOUS GROWTH; GROWTH FACTOR; HEPARIN; IN-VITRO; IN-VIVO; MONOLAYER CULTURE; NUDE MICE; PARTIAL-THICKNESS DEFECT; POLYMER CONCENTRATIONS; RABBIT KNEES;

BODY FLUIDS; CARTILAGE; CELL CULTURE; DEFECTS; MAMMALS; MONOLAYERS; PEPTIDES; POLYSACCHARIDES; REPAIR; SCAFFOLDS (BIOLOGY);

HYDROGELS;

GLYCOSAMINOGLYCAN; HEPARIN; MOLECULAR SCAFFOLD; POLYMER; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CARTILAGE REGENERATION; CELL DAMAGE; CELL DIFFERENTIATION; CELL ENCAPSULATION; CELL REGENERATION; CELL TRANSPORT; CHONDROGENESIS; CONTROLLED STUDY; HYDROGEL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PARTIAL THICKNESS CARTILAGE DEFECT; PRIORITY JOURNAL; RABBIT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; WOUND HEALING;

AGGRECANS; ANIMALS; CARTILAGE; CELL DEDIFFERENTIATION; CHONDROCYTES; CHONDROGENESIS; COLLAGEN TYPE I; COLLAGEN TYPE II; CRYOULTRAMICROTOMY; ELASTIC MODULUS; FEMUR; GLYCOSAMINOGLYCANS; HEPARIN; HYDROGEL; IMMUNOHISTOCHEMISTRY; MICE; RABBITS; REGENERATION; SUBCUTANEOUS TISSUE; SUS SCROFA; TRANSFORMING GROWTH FACTOR BETA1;

MUS MUSCULUS; ORYCTOLAGUS CUNICULUS;

EID: 80051823590     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.07.015     Document Type: Article

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