Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for cartilage tissue engineering

Biomaterials

Volumn 30, Issue 13, 2009, Pages 2499-2506

  Tan, Huaping ^a   Chu, Constance R ^a,b,c   Payne, Karin A ^a   Marra, Kacey G ^a,b,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b University of Pittsburgh   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Biodegradable hydrogel; Bovine articular chondrocytes; Chitosan; Hyaluronic acid; Tissue engineering

Indexed keywords

BIODEGRADABLE COMPOSITES; BIODEGRADABLE HYDROGEL; BIODEGRADABLE SCAFFOLDS; BOVINE ARTICULAR CHONDROCYTES; CARTILAGE TISSUE ENGINEERINGS; CELL SURVIVALS; CHEMICAL CROSS-LINKING; CHONDROCYTIC; COMPOSITE HYDROGELS; COMPRESSIVE MODULUS; EQUILIBRIUM SWELLINGS; EXTRA CELLULAR MATRICES; FT-IR SPECTROSCOPIES; GELATION TIME; GLYCOSAMINOGLYCANS; HYALURONIC ACID; IN-SITU FORMING; IN-VITRO; N SUCCINYL CHITOSANS; NATURAL POLYSACCHARIDES; NEW CLASS; SCHIFF BASE REACTIONS; TISSUE ENGINEERING APPLICATIONS; WATER-SOLUBLE CHITOSANS;

ALDEHYDES; BIODEGRADATION; BIOPOLYMERS; BODY FLUIDS; CHITIN; CHITOSAN; COAGULATION; CROSSLINKING; DRUG DELIVERY; ENGINEERING; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GELATION; HYDROXYLATION; METALLIC MATRIX COMPOSITES; ORGANIC ACIDS; POLYSACCHARIDES; SCAFFOLDS; TISSUE ENGINEERING;

HYDROGELS;

CHITOSAN DERIVATIVE; HYALURONIC ACID; N SUCCINYLCHITOSAN; POLYSACCHARIDE; SCHIFF BASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ARTICULAR CARTILAGE; BIOCOMPATIBILITY; BIODEGRADABLE IMPLANT; CARTILAGE CELL; CELL ENCAPSULATION; CELL STRUCTURE; CELL SURVIVAL; CHEMICAL STRUCTURE; COMPOSITE MATERIAL; COMPRESSION; CONTROLLED STUDY; COW; DEGRADATION; GELATION; HYDROGEL; IN VITRO STUDY; INFRARED SPECTROSCOPY; NONHUMAN; PRIORITY JOURNAL; ROOM TEMPERATURE; SURFACE PROPERTY; SYNTHESIS; TISSUE ENGINEERING;

ANIMALS; CARTILAGE; CATTLE; CELLS, CULTURED; CHITOSAN; HYALURONIC ACID; HYDROGELS; INJECTIONS; MICROSCOPY, ELECTRON, SCANNING; MOLECULAR STRUCTURE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TIME FACTORS; TISSUE ENGINEERING;

BOVINAE;

EID: 60849104777     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.12.080     Document Type: Article

References (36)

1. Tememoff J.S., and Mikos A.G. Injectable biodegradable materials for orthopedic tissue engineering. Biomaterials 21 (2000) 2405-2412
2. Drury J.L., and Mooney D.J. Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials 24 24 (2003) 4337-4351
3. Hou Q.P., De Bank P.A., and Shakesheff K.M. Injectable scaffolds for tissue regeneration. J Mater Chem 14 (2004) 1915-1923
4. Pratt A.B., Weber F.E., Schmoekel H.G., Müller R., and Hubbell J.A. Synthetic extracellular matrices for in situ tissue engineering. Biotechnol Bioeng 86 1 (2004) 27-36
5. Lao L., Tan H., Wang Y., and Gao C. Chitosan modified poly(l-lactide) microspheres as cell microcarriers for cartilage tissue engineering. Colloids Surf B Biointerfaces 66 (2008) 218-225
6. McGlohorn J.B., Grimes L.W., Webster S.S., and Burg K.J.L. Characterization of cellular carriers for use in injectable tissue-engineering composites. J Biomed Mater Res 66A (2003) 441-449
7. Elisseeff J., McIntosh W., Anseth K., Riley S., Ragan P., and Langer R. Photoencapsulation of chondrocytes in poly(ethylene oxide)-based semi-interpenetrating networks. J Biomed Mater Res 51 2 (2000) 164-171
8. DeFail A.J., Chu C.R., Izzo N., and Marra K.G. Controlled release of bioactive TGF-β1 from microspheres embedded within biodegradable hydrogels. Biomaterials 27 (2006) 1579-1585
9. Anseth K.S., Metters A.T., Bryant S.J., Martens P.J., Elisseeff J.H., and Bowman C.N. In situ forming degradable networks and their application in tissue engineering and drug delivery. J Control Release 78 1-3 (2002) 199-209
10. Leach J.B., Bivens K.A., Collins C.N., and Schmidt C.E. Development of photocrosslinkable hyaluronic acid-polyethylene glycol-peptide composite hydrogels for soft tissue engineering. J Biomed Mater Res 70A (2004) 74-82
11. Balakrishnan B., and Jayakrishnan A. Self-cross-linking biopolymers as injectable in situ forming biodegradable scaffolds. Biomaterials 26 (2005) 3941-3951
12. Holland T.A., Tessmar J.K., Tabata Y., and Mikos A.G. Transforming growth factor-beta1 release from oligo(poly(ethylene glycol) fumarate) hydrogels in conditions that model the cartilage wound healing environment. J Control Release 94 1 (2004) 101-114
13. Wieland J.A., Houchin-Ray T.L., and Shea L.D. Non-viral vector delivery from PEG-hyaluronic acid hydrogels. J Control Release 120 (2007) 233-241
14. Moffat K.M., and Marra K.G. Biodegradable poly(ethylene glycol) hydrogels crosslinked with genipin for tissue engineering applications. J Biomed Mater Res Part B Appl Biomater 71B (2004) 181-187
15. Bouhadir K.H., Kruger G.M., Lee K.Y., and Mooney D.J. Sustained and controlled release of daunomycin from cross-linked poly(aldehyde guluronate) hydrogels. J Pharm Sci 89 (2000) 910-919
16. Sung H.W., Huang R.N., Huang L.L.H., Tsai C.C., and Chiu C.T. Feasibility study of a natural crosslinking reagent for biological tissue fixation. J Biomed Mater Res 42 (1998) 560-567
17. Ferretti M., Marra K.G., Kobayashi K., Defail A.J., and Chu C.R. Controlled in vivo degradation of genipin crosslinked polyethylene glycol hydrogels within osteochondral defects. Tissue Eng 12 9 (2006) 2657-2663
18. Maia J., Ferreira L., Carvalho R., Ramos M.A., and Gil M.H. Synthesis and characterization of new injectable and degradable dextran-based hydrogels. Polymer 46 (2005) 9604-9614
19. Nishi K.K., and Jayakrishnan A. Preparation and in vitro evaluation of primaquine-conjugated gum arabic microspheres. Biomacromolecules 5 (2004) 1489-1495
20. Wang D.A., Varghese S., Sharma B., Strehin I., Fermanian S., Gorham J., et al. Multifunctional chondroitin sulphate for cartilage tissue-biomaterial integration. Nat Mater 6 5 (2007) 385-392
21. Ruhela D., Riviere K., and Szoka F.C. Efficient synthesis of an aldehyde functionalized hyaluronic acid and its application in the preparation of hyaluronan-lipid conjugates. Bioconjug Chem 17 (2006) 1360-1363
22. Ito T., Yeo Y., Highley C.B., Bellas E., Benitez C.A., and Kohane D.S. The prevention of peritoneal adhesions by in situ cross-linking hydrogels of hyaluronic acid and cellulose derivatives. Biomaterials 28 (2007) 975-983
23. Di Martino A., Sittinger M., and Risbud M.V. Chitosan: a versatile biopolymer for orthopaedic tissue-engineering. Biomaterials 26 (2005) 5983-5990
24. Kim S.E., Park J.H., Cho Y.W., and Chung H. Porous chitosan scaffold containing microspheres loaded with transforming growth factor: implication for cartilage tissue engineering. J Control Release 91 (2003) 365-374
25. Tan H., Gong Y., and Gao C. Gelatin/chitosan/hyaluronan ternary complex scaffold containing basic fibroblast growth factor for cartilage tissue engineering. J Mater Sci Mater Med 18 (2007) 1961-1968
26. Kato Y., Onishi H., and Machida Y. Biological characteristics of lactosaminated N-succinyl-chitosan as a liver-specific drug carrier in mice. J Control Release 70 (2001) 295-307
27. Sun S., and Wang A. Adsorption properties of N-succinyl-chitosan and cross-linked N-succinyl-chitosan resin with Pb(II) as template ions. Sep Purif Technol 51 (2006) 409-415
28. Kato Y., Onishi H., and Machida Y. Lactosaminated and intact N-succinyl-chitosans as drug carriers in liver metastasis. Int J Pharm 226 (2001) 93-106
29. Ameer G.A., Mahmood T.A., and Langer R. A biodegradable composite scaffold for cell transplantation. J Orthop Res 20 (2002) 16-19
30. Fan H.B., Hu Y.Y., Qin L., Li X.S., Wu H., and Lv R. Porous gelatin-chondroitin-hyaluronate tri-copolymer scaffold containing microspheres loaded with TGF-β1 induces differentiation of mesenchymal stem cells in vivo for enhancing cartilage repair. J Biomed Mater Res 77A (2006) 785-794
31. Bulpitt P., and Aeschlimann D. New strategy for chemical modification of hyaluronic acid: preparation of functionalized derivatives and their use in the formation of novel biocompatible hydrogels. J Biomed Mater Res 47 (1999) 152-169
32. Curotto E., and Aros F. Quantitative determination of chitosan and the percentage of free amino groups. Anal Biochem 211 (1993) 240-241
33. Bouhadir K.H., Hausman D.S., and Mooney D.J. Synthesis of cross-linked poly(aldehyde guluronate) hydrogels. Polymer 40 (1999) 3575-3584
34. Karpie J., and Chu C.R. Lidocaine exhibits dose- and time-dependent cytotoxic effects on bovine articular chondrocytes in vitro. Am J Sports Med 35 (2007) 1621-1627
35. Chu C.R., Izzo N., Papas N.E., and Fu F.H. In vitro exposure to 0.5% bupivacaine is cytotoxic to bovine articular chondrocytes. Arthrosc 22 (2006) 693-699
36. Marra K.G., DeFail A.J., Clavijo-Alvarez J.A., Badylak S.F., Taieb A., Schipper B., et al. FGF-2 enhances vascularization for adipose tissue engineering. Plast Reconstr Surg 121 4 (2008) 1153-1164