Biodegradable thermogels

Accounts of Chemical Research

Volumn 45, Issue 3, 2012, Pages 424-433

  Park, Min Hee ^a   Joo, Min Kyung ^a   Choi, Bo Gyu ^a   Jeong, Byeongmoon ^a  

^a Ewha Womans University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE; POLOXAMER; POLYMER;

ANIMAL; ARTICLE; CHEMISTRY; DRUG DELIVERY SYSTEM; GEL; METHODOLOGY; RAT; TISSUE ENGINEERING;

ANIMALS; DRUG DELIVERY SYSTEMS; GELS; PEPTIDES; POLOXAMER; POLYMERS; RATS; TISSUE ENGINEERING;

EID: 84858654349     PISSN: 00014842     EISSN: 15204898     Source Type: Journal    
DOI: 10.1021/ar200162j     Document Type: Article

References (68)

1. Loh, X. J.; Li, J. Biodegradable Thermosensitive Copolymer Hydrogels for Drug Delivery Expert Opin. Ther. Pat. 2007, 17, 965-977 (Pubitemid 47342746)
2. Yu, L.; Ding, J. Injectable Hydrogels as Unique Biomedical Materials Chem. Soc. Rev. 2008, 37, 1473-1481
3. Joo, M.; Park, M. H.; Choi, B. G.; Jeong, B. Reverse Thermogelling Biodegradable Polymer Aqueous Solutions J. Mater. Chem. 2009, 19, 5891-5905
4. Jeong, B.; Bae, Y. H.; Kim, S. W. Thermoreversible Gelation of PEG-PLGA-PEG Triblock Copolymer Aqueous Solutions Macromolecules 1999, 32, 7064-7069 (Pubitemid 32079730)
5. Jeong, B.; Bae, Y. H.; Kim, S. W. In Situ Gelation of PEG-PLGA-PEG Triblock Copolymer Aqueous Solutions and Degradation Thereof J. Biomed. Mater. Res. 2000, 50, 171-177
6. Jeong, B.; Bae, Y. H.; Kim, S. W. Drug Release from Biodegradable Injectable Thermosensitive Hydrgel of PEG-PLGA-PEG Triblock Copolymers J. Controlled Release 2000, 63, 155-163 (Pubitemid 30046951)
7. Rathi, R.; Zentner, G.; Jeong, B. Biodegradable Low Molecular Weight Triblock Poly(lactide- co -glycolide) Polyethylene Glycol Copolymers Having Reverse Thermal Gelation Properties. U.S. Patent 6,117,949, 2000; U.S. Patent 6,201,072, 2001.
8. Chenite, A.; Chaput, C.; Wang, D.; Combes, C.; Buschmann, M. D.; Hoeman, C. D.; Leroux, J. C.; Atkinson, B. L.; Binette, F.; Selmani, A. Novel Injectable Neutral Solutions of Chitosan Form Biodegradable Gels in situ Biomaterials 2000, 21, 2155-2161 (Pubitemid 30612386)
9. Lee, B. H.; Lee, Y. M.; Sohn, Y. S.; Song, S. C. A Thermosensitive Poly(organophosphazene) Gel Macromolecules 2002, 35, 3876-3879 (Pubitemid 34711545)
10. Potta, T.; Chun, C. J.; Song, S. C. Injectable, Dual Cross-Linkable Polyphosphazene Blend Hydrogels Biomaterials 2010, 31, 8107-8120
11. Park, M. R.; Chun, C. J.; Ahn, S. W.; Ki, M. H.; Cho, C. S.; Song, S. C. Sustained Delivery of Human Growth Hormone Using a Polyelectrolyte Complex-Loded Thermosensitive Polyphosphazene Hydrogel J. Controlled Release 2010, 147, 359-367
12. Hwang, M.; Suh, J. M.; Bae, Y. H.; Kim, S. W.; Jeong, B. Caprolactonic Poloxamer Analog: PEG-PCL-PEG Biomacromolecules 2005, 6, 885-890 (Pubitemid 40467832)
13. Bae, S. J.; Suh, J. M.; Sohn, Y. S.; Bae, Y. H.; Kim, S. W.; Jeong, B. Thermogelling Poly(caprolactone- b -ethylene glycol- b -caprolactone) Aqueous Solutions Macromolecules 2005, 38, 5260-5265 (Pubitemid 40925687)
14. Park, S. H.; Choi, B. G.; Joo, M. K.; Han, D. K.; Sohn, Y. S.; Jeong, B. Temperature-sensitive Poly(caprolactone- co -trimethylene carbonate)- Poly(ethylene glycol)-Poly(caprolactone- co -trimethylene carbonate) as In Situ Gel-Forming Biomaterial Macromolecules 2008, 41, 6486-6492
15. Zhang, Z.; Ni, J.; Chen, L.; Yu, L.; Xu, J.; Ding, J. Biodegradable and Thermoreversible PCLA-PEG-PCLA Hydrogel as a Barrier for Prevention of Post-Operative Adhesion Biomaterials 2011, 32, 4725-4736
16. Hyun, H.; Kim, Y. H.; Song, I. B.; Lee, J. W.; Kim, M. S.; Khang, G.; Park, K.; Lee, H. B. In Vitro and In Vivo Release of Albumin Using a Biodegradable mPEG-PCL Diblock Copolymer as an In Situ Gel-Forming Carrier Biomacromolecules 2007, 8, 1093-1100 (Pubitemid 46672685)
17. Kim, S. Y.; Kim, H. J.; Lee, K. E.; Han, S. S.; Sohn, Y. S.; Jeong, B. Reverse Thermal Gelling PEG-PTMC Diblock Copolymer Aqueous Solution Macromolecules 2007, 40, 5519-5525 (Pubitemid 47210179)
18. Loh, X. J.; Goh, S. H.; Li, J. New Biodegradable Thermogelling Copolymers Having Very Low Gelation Concentrations Biomacromolecules 2007, 8, 585-593 (Pubitemid 46323277)
19. Loh, X.; Nguyen, V. P. N.; Kuo, N.; Li, J. Encapsulation of Basic Fibroblast Growth Factor in Thermogelling Copolymers Preserves Its Bioactivity J. Mater. Chem. 2011, 21, 2246-2254
20. Sosnik, A.; Cohn, D. Reverse Thermo-Responsive Poly(ethylene oxide) and Poly(propylene oxide) Multiblock Copolymers Biomaterials 2005, 26, 349-357 (Pubitemid 38951102)
21. Choi, B. G.; Sohn, Y. S.; Jeong, B. Closed-Loop Sol-Gel Transition of PEG-PEC Aqueous Solution J. Phys. Chem. B 2007, 111, 7715-7718 (Pubitemid 47169680)
22. Schacht, E.; Toncheva, V.; Vandertaelen, K.; Heller, J. Polyacetal and Poly(ortho ester)-Poly(ethylene glycol) Graft Copolymer Thermogels: Preparation, Hydrolysis and FITC-BSA Release Studies J. Controlled Release 2006, 116, 219-225 (Pubitemid 44854284)
23. Vermonden, T.; Besseling, N. A. M.; Steenbergen, M. J.; Hennink, W. E. Rheological Studies of Thermosensitive Triblock Copolymer Hydrogels Langmuir 2006, 22, 10180-10184 (Pubitemid 46079304)
24. Wang, J.; Sun, D. D. N.; Shin-Ya, Y.; Leong, K. W. Stimuli-Responsive Hydrogel Based on Poly(propylene phosphate) Macromolecules 2004, 37, 670-672
25. Jeong, Y.; Joo, M. K.; Sohn, Y. S.; Jeong, B. Reverse Thermal Organogel Adv. Mater. 2007, 19, 3947-3950
26. Choi, Y. Y.; Joo, M. K.; Sohn, Y. S.; Jeong, B. Significance of Secondary Structure in Nanostructure Formation and Thermosensitivity of Polypeptide Block Copolymer Soft Matter 2008, 4, 2383-2387
27. Oh, H. J.; Joo, M. K.; Sohn, Y. S.; Jeong, B. Secondary Structure Effect of Polypeptide on Reverse Thermal Gelation and Degradation of L/DL-Poly(alanine)-Poloxamer-L/DL-Poly(alanine) Copolymers Macromolecules 2008, 41, 8204-8209
28. Jeong, Y.; Joo, M. K.; Bahk, K. H.; Choi, Y. Y.; Kim, H. T.; Kim, W. K.; Lee, H. J.; Sohn, Y. S.; Jeong, B. Enzymatically Degradable Temperature- Sensitive Polypeptide as a New In-Situ Gelling Biomaterial J. Controlled Release 2009, 137, 25-30
29. Kim, J. Y.; Park, M. H.; Joo, M. K.; Lee, S. Y.; Jeong, B. End Groups Adjust Molecular Nano-Assembly Pattern and Thermal Gelation of Polypeptide Block Copolymer Aqueous Solution Macromolecules 2009, 42, 3147-3151
30. Choi, Y. Y.; Jang, J. H.; Park, M. H.; Choi, B. G.; Chi, B.; Jeong, B. Block Length Affects Secondary Structure, Nanoassembly and Thermosensitivity of Poly(ethylene glycol)-Poly(L-alanine) Block Copolymer J. Mater. Chem. 2010, 20, 3416-3421
31. Choi, B. G.; Park, M. H.; Cho, S. H.; Joo, M. K.; Oh, H. J.; Kim, E. H.; Park, K.; Han, D. K.; Jeong, B. In Situ Thermal Gelling Polypeptide for Chondrocytes 3D Culture Biomaterials 2010, 31, 9266-9272
32. Huynh, D. P.; Im, G. J.; Chae, S. Y.; Lee, K. C.; Lee, D. S. Controlled Release of Insulin from pH/Temperature-Sensitive Injectable Pentablock Copolymer J. Controlled Release 2009, 137, 20-24
33. Garbern, J. C.; Hoffman, A. S.; Stayton, P. S. Injectable pH- and Temperature-Responsive Poly(N -isopropylacrylamide- co -propylacrylic acid) Copolymers for Delivery of Angiogenic Growth Factors Biomacromolecules 2010, 11, 1833-1839
34. Jang, J. H.; Choi, Y. M.; Choi, Y. Y.; Joo, M. K.; Park, M. H.; Choi, B. G.; Kang, E. Y.; Jeong, B. pH/Temperature Sensitive Chitosan- g -(PA-PEG) Aqueous Solutions as New Thermogelling Systems J. Mater. Chem. 2011, 21, 5484-5491
35. Suh, J. M.; Bae, S. J.; Jeong, B. Thermogelling Multiblock Poloxamer Aqueous Solutions with Closed-Loop Sol-Gel-Sol Transition by Increasing pH Adv. Mater. 2005, 17, 118-120 (Pubitemid 40178461)
36. Chang, G.; Yu, L.; Yang, Z.; Ding, J. A Delicate Ionizable-Group Effect on Self-Assembly and Thermogelling of Amphiphilic Block Copolymers in Water Polymer 2009, 50, 6111-6120
37. Elstad, N. L.; Fowers, K. D. OncoGel (ReGel/paclitaxel)-Clinical Applications for a Novel Paclitaxel Delivery System Adv. Drug Delivery Rev. 2009, 61, 785-794
38. Xiong, X. Y.; Tam, K. C.; Gan, L. H. Synthesis and Thermal Responsive Properties of P(LA- b -EO- b -PO- b -EO- b -LA) Block Copolymers with Short Hydrophobic Poly(lactic acid) (PLA) Segments Polymer 2005, 46, 1841-1850 (Pubitemid 40254898)
39. Batrakova, E. V.; Kabanov, A. V. Pluronic Block Copolymers: Evolution of Drug Delivery Concept from Inert Nanocarriers to Biological Response Modifiers J. Controlled Release 2008, 130, 98-106
40. Jeong, B.; Bae, Y. H.; Lee, D. S.; Kim, S. W. Biodegradable Block Copolymers as Injectable Drug-Delivery Systems Nature 1997, 388, 860-862 (Pubitemid 27377054)
41. Mortensen, K.; Perdersen, S. Structural Study on Micelle Formation of Poly(ethylene oxide)- Poly(propylene oxide)-Poly(ethylene oxide) Triblock Copolymer in Aqueous Solution Macromolecules 1993, 26, 805-812
42. Zhang, H.; Yu, L.; Ding, J. Roles of Hydrophilic Homopolymers on the Hydrophobic-Association-Induced Physical Gelling of Amphiphilic Block Copolymers in Water Macromolecules 2008, 41, 6493-6499
43. Yu, L.; Zhang, Z.; Zhang, H.; Ding, J. Biodegradability and Biocompatibility of Thermoreversible Hydrogels Formed from Mixing a Sol and a Precipitate of Block Copolymers in Water Biomacromolecules 2010, 11, 2169-2178
44. Jeong, B.; Kibbey, M. R.; Birnbaum, J. C.; Won, Y. Y.; Gutowska, A. Thermogelling Biodegradable Polymers with Hydrophilic Backbones: PEG- g -PLGA Macromolecules 2000, 33, 8317-8322 (Pubitemid 32031177)
45. Jeong, B.; Wang, L. Q.; Gutowska, A. Biodegradable Thermoreversible Gelling PLGA- g -PEG Copolymer Chem. Commun. 2001, 16, 1516-1517 (Pubitemid 32747827)
46. Jeong, B.; Gutowska, A. Thermogelling Biodegradable Aqueous Polymer Solution. U.S. Patent 6,841,617, 2005.
47. Jeong, B.; Lee, K. M.; Gutowska, A.; An, Y. H. Thermogelling Biodegradable Copolymers Aqueous Solutions for Injectable Protein Delivery and Tissue Engineering Biomacromolecules 2002, 3, 865-868
48. Behravesh, E.; Shung, A. K.; Jo, S.; Mikos, A. G. Synthesis and Characterization of Triblock Copolymers of Methoxy Poly(ethylene glycol) and Poly(propylene fumarate) Biomacromolecules 2002, 3, 153-158 (Pubitemid 34121170)
49. Ahn, J. S.; Suh, J. M.; Lee, M. Y.; Jeong, B. Slow Eroding Biodegradable Multiblock Poloxamer Polym. Int. 2005, 54, 842-847 (Pubitemid 40533803)
50. Borden, B. A.; Yockman, J.; Kim, S. W. Thermoresponsive hydrogel as a delivery scaffold for transfected rat mesenchymal stem cells Mol. Pharmaceutics 2010, 7, 963-968
51. Garripelli, V. K.; Kim, J. K.; Son, S.; Kim, W. J.; Jo, S. Matrix Metalloproteinase-Sensitive Thermogelling Polymer for Bioresponsive Local Drug Delivery Acta Biomater. 2011, 7, 1984-1992
52. Russo, A.; DeGraft, W.; Friedman, N.; Mitchell, J. B. Selective Modulation of Glutathione Levels in Human Normal Versus Tumor Cells and Subsequent Differential Response to Chemotherapy Drugs Cancer Res. 1986, 46, 2845-2848 (Pubitemid 16074292)
53. Sun, K. H.; Sohn, Y. S.; Jeong, B. Thermogelling Poly(ethylene oxide- b -propylene oxide- b -ethylene oxide) Disulfide Multiblock Copolymer as a Thiol-Sensitive Degradable Polymer Biomacromolecules 2006, 7, 2871-2877 (Pubitemid 44615272)
54. Whitmore, L.; Wallace, B. A. Protein Secondary Structure Analyses from Circular Dichroism Spectroscopy: Methods and Reference Databases Biopolymers 2008, 89, 392-400
55. Petka, W. A.; Harden, J. L.; Mcgrath, K. P.; Wirtz, D.; Tirrell, D. A. Reversible Hydrogels from Self-Assembling Artificial Proteins Science 1998, 281, 389-392 (Pubitemid 28340778)
56. Wang, C.; Stewart, R. J.; Kopecek, J. Hybrid Hydrogels Assembled from Synthetic Polymers and Coiled-Coil Protein Domains Nature 1999, 397, 417-420
57. Kim, H. J.; Kim, T.; Lee, M. Responsive Nanostructures from Aqueous Assembly of Rigid-Flexible Block Molecules Acc. Chem. Res. 2011, 44, 72-82
58. Yu, L.; Zhang, H.; Ding, J. A Subtle End-Group Effect on Macroscopic Physical Gelation of Triblock Copolymer Aqueous Solutions Angew. Chem., Int. Ed. 2006, 45, 2232-2235 (Pubitemid 44105150)
59. Kim, E. H.; Joo, M. K.; Bahk, K. H.; Park, M. H.; Chi, B.; Lee, Y. M.; Jeong, B. Reverse Thermal Gelation of PAF-PLX-PAF block Copolymer Aqueous Solution Biomacromolecules 2009, 10, 2476-2481
60. Moon, H. J.; Choi, B. G.; Park, M. H.; Joo, M. K.; Jeong, B. Enzymatically Degradable Thermogelling Poly(alanine- co -leucine)-Poloxamer- Poly(alanine- co -leucine) Biomacromolecules 2011, 12, 1234-1242
61. Park, S. H.; Choi, B. G.; Moon, H. J.; Cho, S. H.; Jeong, B. Block Sequence Affects Thermosensitivity and Nano-Assembly: PEG-L-PA-DL-PA and PEG-DL-PA-L-PA Block Copolymers Soft Matter 2011, 7, 6515-6521
62. Han, J. O.; Joo, M. K.; Jang, J. H.; Park, M. H.; Jeong, B. PVPylated Poly(alanine) as a New Thermogelling Polymer Macromolecules 2009, 42, 6710-6715
63. Dvir, T.; Timko, B. P.; Kohane, D. S.; Langer, R. Nanotechnological Strategies for Engineering Complex Tissues Nat. Nanotechnol. 2011, 6, 13-22
64. Banwell, E. F.; Abelardo, E. S.; Adams, D. J.; Birchall, M. A.; Corrigan, A.; Donald, A. M.; Kirkland, M.; Serpell, L. C.; Butler, M. F.; Woolfson, D. N. Rational Design and Application of Responsive α-Helical Peptide Hydrogels Nat. Mater. 2009, 8, 596-600
65. Pek, Y. S.; Wan, A. C. A.; Yang, J. Y. The Effect of Matrix Stiffness on Mesenchymal Stem Cell Differentiation in a 3D Thixotropic Gel Biomaterials 2009, 31, 385-391
66. Choi, B. G.; Park, M. H.; Cho, S. H.; Joo, M. K.; Oh, H. J.; Kim, E. H.; Park, K.; Han, D. K.; Jeong, B. Thermal Gelling Polyalanine-Poloxamine- Polyalanine Aqueous Solution for Chondrocytes 3D Culture: Initial Concentration Effect Soft Matter 2011, 7, 456-462
67. Bright, L. J.; Kambesis, N.; Nelson, S. B.; Jeong, B.; Turkewitz, A. P. Comprehensive Analysis Reveals Dynamic and Evolutionary Plasticity of Rab GTPases and Membrane Traffic in Tetrahymena Thermophila PLoS Genet. 2010, 6, 1-18
68. Engler, A. J.; Sen, S.; Sweeney, H. L.; Discher, D. E. Matrix Elasticity Directs Stem Cell Lineage Specification Cell 2006, 126, 677-689 (Pubitemid 44233625)