An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate

Biomaterials

Volumn 32, Issue 2, 2011, Pages 587-597

  Pritchard, Christopher D ^a   O'Shea, Timothy M ^b   Siegwart, Daniel J ^a   Calo, Eliezer ^b   Anderson, Daniel G ^a   Reynolds, Francis M ^c   Thomas, John A ^d   Slotkin, Jonathan R ^d   Woodard, Eric J ^e   Langer, Robert ^a,b  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c InVivo Therapeutics Corporation   (United States)

^d Washington Brain and Spine Institute   (United States)

^e NEW ENGLAND BAPTIST HOSPITAL   (United States)

Author keywords

Cell adhesion; Controlled drug release; Hydrogel; Peptide; Polyethylene oxide; Spinal surgery

Indexed keywords

AQUEOUS MEDIA; BIOLOGICAL PROPERTIES; CONTROLLED DRUG RELEASE; FUNCTIONALIZATIONS; INJECTABLE HYDROGELS; LOADING EFFICIENCY; MESENCHYMAL STEM CELL; MESH SIZE; MICHAEL ADDITIONS; MONOMER CONVERSIONS; POLY(ETHYLENE GLYCOL) HYDROGEL; RATIONAL DESIGN; SODIUM SUCCINATE; SOFT HUMAN TISSUES; SOL FRACTION; SPINAL SURGERY; SUSTAINED RELEASE; TECHNICAL CHALLENGES;

ADDITION REACTIONS; ADHESION; BIOLOGICAL MATERIALS; BIOMECHANICS; CELL ADHESION; CELL CULTURE; COAGULATION; DRUG PRODUCTS; ETHYLENE; ETHYLENE GLYCOL; GELATION; IMPLANTS (SURGICAL); MECHANICAL PROPERTIES; PEPTIDES; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYETHYLENES; SODIUM; STEM CELLS; SURGERY; THERMOPLASTICS;

HYDROGELS;

ACRYLIC ACID; MACROGOL; METHYLPREDNISOLONE SODIUM SUCCINATE; MONOMER; THIOL;

ANIMAL CELL; AQUEOUS SOLUTION; ARTICLE; GELATION; HUMAN; HUMAN TISSUE; HYDROGEL; MESENCHYMAL STEM CELL; MICHAEL ADDITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOLID STATE; SUSTAINED DRUG RELEASE;

ANIMALS; CELLS, CULTURED; HYDROGELS; INJECTIONS; MESENCHYMAL STEM CELLS; METHYLPREDNISOLONE HEMISUCCINATE; MICE; POLYETHYLENE GLYCOLS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SULFHYDRYL COMPOUNDS;

MURINAE;

EID: 78449240894     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.08.106     Document Type: Article

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