Novel injectable pH and temperature sensitive block copolymer hydrogel

Biomacromolecules

Volumn 6, Issue 6, 2005, Pages 2930-2934

  Shim, Woo Sun ^a   Yoo, Jae Sun ^a   Bae, You Han ^b   Lee, Doo Sung ^a  

^a Sungkyunkwan University   (South Korea)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOCK COPOLYMERS; CONTROLLED DRUG DELIVERY; GELATION; HYDROPHILICITY; HYDROPHOBICITY; MOLECULAR WEIGHT; PH EFFECTS; PHASE TRANSITIONS; SOL-GELS; THERMAL EFFECTS;

MOLECULAR WEIGHT CONTROL; SENSITIVE MOIETY; SOL-GEL TRANSITION; TEMPERATURE SENSITIVE BLOCK COPOLYMER;

HYDROGELS;

COPOLYMER; DRUG; DRUG CARRIER; MACROGOL; POLYCAPROLACTONE; PROTEIN; SULFADIMIDINE;

ACIDITY; ALKALINITY; ARTICLE; BODY TEMPERATURE; CATHETER; CYTOTOXICITY; DRUG DELIVERY SYSTEM; GELATION; HYDROGEL; HYDROPHILICITY; HYDROPHOBICITY; INJECTION; LIQUID; MOLECULAR WEIGHT; NEEDLE; PH; PHASE TRANSITION; PRIORITY JOURNAL; ROOM TEMPERATURE; TEMPERATURE SENSITIVITY;

BIOCOMPATIBLE MATERIALS; BODY TEMPERATURE; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GELS; HUMANS; HYDROGEL; HYDROGELS; HYDROGEN-ION CONCENTRATION; INJECTIONS; MACROMOLECULAR SUBSTANCES; MODELS, CHEMICAL; MOLECULAR WEIGHT; PHASE TRANSITION; POLYETHYLENE GLYCOLS; POLYMERS; TEMPERATURE; VISCOSITY;

EID: 28844483415     PISSN: 15257797     EISSN: None     Source Type: Journal    
DOI: 10.1021/bm050521k     Document Type: Article

References (23)

1. (a) Chen, G.; Hoffman, A. S. Nature 1995, 373, 49.
2. (b) Jeong, B. M.; Bae, Y. H.; Lee, D. S.; Kim, S. W. Nature 1997, 388, 860.
3. Mahnsten, M.; Lindman, B. Macromolecules 1992, 25, 5446.
4. (a) Yang, Z.; Pickard, S.; Deng, N.; Barlow, R. J.; Attwood, D.; Booth, C. Macromolecules 1994, 27, 2371.
5. (b) Alexandridis, P.; Hatton, T. A. Colloids Surf. A: Physicochem. Eng. Aspects 1995, 96, 1.
6. (c) Vadnere, M.; Amidon, G.; Lingdenbaum, S.; Haslam, J. L. Int. J. Pharm. 1984, 22, 207.
7. (d) Attwood, D.; Collett, J. H.; Tait, C. J. Int. J. Pharm. 1985, 26, 25.
8. (a) Rashkov, I.; Manolova, N.; Li, S. M.; Espartero, J. L.; Vert, M. Macromolecules 1992, 29, 50.
9. (b) Cerrai, P.; Tricoli, M.; Lelli, L.; Guerra, G. D.; Sbarbati Del Guerra, R.; Cascone, M. G.; Giusti, P. J. Mater. Sci., Mater. Med. 1994, 5, 308.
10. (c) Jeong, B. M.; Bae, Y. H.; Kim, S. W. Macromolecules 1999, 32, 7064.
11. (a) Chenite, A.; Chaput, C.; Wang, D.; Combes, C.; Buschmann, M. D.; Hoemann, C. D.; Leroux, J. C.; Atkinson, B. L.; Binette, F.; Selmani, A. Biomaterials 2000, 21, 2155.
12. (b) Han, H. D.; Nam, D. E.; Seo, D. H.; Kim, T. W.; Shin, B. C. Macromolecular Res. 2004, 12,507.
13. (a) Tanigami, T.; Ono, T.; Suda, N.; Sakamaki, Y.; Yamaura, K.; Matsuzawa, S. Macromolecules 1989, 22, 1397.
14. (b) Lee, B. H.; Lee, Y. M.; Sohn, Y. S.; Song, S. C. Polym. Int. 2002, 51, 658.
15. Liang, H.; Hon, M.; Ho, R.; Chung, C.; Lin, Y.; Chen, C.; Sung, H. Biomacromoleules 2004, 5, 1917.
16. (a) Lee, D. S.; Shim, M. S.; Kim, S. W.; Lee, H.; Park, I.; Chang, T. Macromol. Rap. Commun. 2001, 22, 587.
17. (b) Jeong, B. M.; Bae, Y. H.; Kim, S. W. J. Controlled Release 2000, 63, 155.
18. (a) Domb, A.; Turovsky, L.; Nudelman, R. Pharm. Res. 1994, 11, 865.
19. (b) Middaugh, C. R.; Evans, R. K.; Montgomery, D. L.; Casimiro, D. R. J. Pharm. Sci. 1998, 87, 130.
20. (c) Fu, K.; Pack, D. W.; Klibanov, A. M.; Langer, R. Pharm. Res. 2000, 17, 100.
21. (a) Han, S. K.; Na, K.; Bae, Y. H. Colloids Surf A: Physicochem. Eng. Aspects 2003, 214, 49.
22. (b) Kang, S. L; Bae, Y. H. Macromolecules 2001, 34, 8173.
23. (c) Kang, S. I.; Na, K.; Bae, Y. H. Macromol. Symp. 2001, 172, 149.