A thermo-sensitive poly(organophosphazene) hydrogel used as an extracellular matrix for artificial pancreas

Journal of Biomaterials Science, Polymer Edition

Volumn 16, Issue 11, 2005, Pages 1421-1431

  Park, Keun Hong ^a   Song, Soo Chang ^b  

^a Ajou University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

Author keywords

Biodegradation; Hydrogel; Injectable; Poly(organophosphazene); Thermo sensitive

Indexed keywords

ARTIFICIAL ORGANS; BIODEGRADATION; BIOLOGICAL MATERIALS; CELLS; GELS; INSULIN; PHASE TRANSITIONS; POLYETHYLENE GLYCOLS; SOLS;

ARTIFICIAL PANCREAS; EXTRACELLULAR MATRIX; POLYORGANOPHOSPHAZENE;

HYDROGELS;

BIOMATERIAL; BUFFER; ESTER DERIVATIVE; GLUCOSE; INSULIN; ISOLEUCINE; MACROGOL DERIVATIVE; POLY(ORGANOPHOSPHAZENE); POLYMER; UNCLASSIFIED DRUG; ORGANIC COMPOUND;

ANIMAL CELL; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; ARTIFICIAL PANCREAS; BIODEGRADABILITY; CELL CULTURE; CELL TYPE; CELL VIABILITY; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EXTRACELLULAR MATRIX; GEL; HEAT SENSITIVITY; HYDROGEL; HYDROPHOBICITY; INSULIN RELEASE; INSULIN SYNTHESIS; MALE; MOLECULAR WEIGHT; NERVE CELL; NERVE REGENERATION; NONHUMAN; PANCREAS ISLET; PHASE TRANSITION; PRIORITY JOURNAL; RAT; TEMPERATURE MEASUREMENT; TURBIDITY; ANIMAL; CHEMICAL MODEL; CHEMISTRY; DOSE RESPONSE; FOURIER ANALYSIS; HEAT; METABOLISM; NECROSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PANCREAS; SECRETION; TEMPERATURE; TIME;

ANIMALS; BIOCOMPATIBLE MATERIALS; BUFFERS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR MATRIX; FOURIER ANALYSIS; GELS; GLUCOSE; HEAT; HYDROGELS; INSULIN; ISLETS OF LANGERHANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; NECROSIS; ORGANIC CHEMICALS; PANCREAS; PANCREAS, ARTIFICIAL; POLYETHYLENE GLYCOLS; POLYMERS; RATS; TEMPERATURE; TIME FACTORS;

EID: 33644819367     PISSN: 09205063     EISSN: None     Source Type: Journal    
DOI: 10.1163/156856205774472272     Document Type: Article

References (25)

1. T. D. Sielaff, S. L. Nyberg, M. D. Rollins, M. Y. Hu, B. Amiot, A. Lee, F. J. Wu, W. S. Hu and F. B. Cerra, Cell Biol. Toxicol. 13, 357 (1997).
2. A. L. Koenig, V. Gambillara and D. W. Grainger, J. Biomed. Mater. Res. 64, 20 (2003).
3. S. Chandrasekaran, J. W. Dean III, M. S. Giniger and M. L. Tanzer, J. Cell Biochem. 46, 115 (1991).
4. P. Aebischer, M. Goddard, A. P. Signore and R. L. Timpson, Exp. Neurol. 126, 151 (1994).
5. T. G. Wang, Artif. Organ. 22, 68 (1988).
6. S. Woerly, R. Marchand and A. Lavallee, Biomaterials 11, 97 (1990).
7. G. King and M. Ashby, Cellular Solids: Structure and Properties. Pergamon Press, New York, NY (1988).
8. S. Halstenberg, A. Panitch, S. Rizzi, H. Hall and J. A. Hubbell, Biomacromolecules 3, 710 (2003).
9. N. Tirelli, M. P. Lutolf, A. Napoli and J. A. Hubbell, J. Biotechnol. 90, 3 (2002).
10. G. M. Cruise, D. S. Scharp and J. A. Hubbell, Biomaterials 19, 1287 (1998).
11. B. Vernon, S. W. Kim and Y. H. Bae, J. Biomater. Sci. Polymer Edn 10, 183 (1999).
12. K. Y. Lee and D. J. Mooney, Chem. Rev. 101, 1869 (2001).
13. L. E. Bromberg and E. S. Ron, Adv. Drug Deliv. Rev. 31, 197 (1998).
14. A. S. Hoffman, Adv. Drug Deliv. Rev. 43, 3 (2002).
15. Y. Qiu and K. Park, Adv. Drug Deliv. Rev. 53, 321 (2002).
16. B. Jeong, Y. H. Bae and S. W. Kim, Adv. Drug Deliv. Rev. 54, 37 (2002).
17. B. H. Lee, Y. M. Lee, Y. S. Sohn and S. C. Song, Macromolecules 35, 3876 (2002).
18. B. H. Lee and S. C. Song, Macromolecules 37, 4533 (2004).
19. J. D. Greenstein and M. Winitz, Chemistry of the Amino Acids. Wiley, New York, NY (1961).
20. J. Loccufier, J. Crommen, J. Vandorpe and E. Schacht, Makromol. Chem. Rapid Commun. 12, 159 (1991).
21. P. E. Lancy and M. Kostianovsky, Diabetes 16, 35 (1967).
22. P. Memnyi, S. K. Dixon, N. B. White Jr. and M. L. Hedstrom, Statistics From Scratch. Holden-Day, Oakland, CA (1976).
23. J. Schrezenmeir, B. J. Hering, L. Gerio, J. Wiegand-Dressler, M. Solhdju, F. Velten, J. Kirchgessner, C. Laue, J. Beyer, R. Bretzel and K. Federlin, Horm. Metab. Res. 25, 204 (1993).
24. A. Gaber, D. W. Fraga, C. S. Callicutt, I. C. Gerling, O. M. Sabek and M. Y. Kotb, Transplantation 72, 1730 (2001).
25. D. Brandhorst, H. Brandhorst, B. J. Hering and R. G. Bretzel, Transplantation 67, 1533 (1999).