Biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PCL-PEG-PCL hydrogel. Part 2: Sol-gel-sol transition and drug delivery behavior

Acta Biomaterialia

Volumn 5, Issue 9, 2009, Pages 3358-3370

  Gong, ChangYang ^a   Shi, Shuai ^a   Wu, Lan ^a   Gou, MaLing ^a   Yin, QinQin ^a   Guo, QingFa ^a   Dong, PengWei ^a   Zhang, Fan ^a   Luo, Feng ^a   Zhao, Xia ^a   Wei, YuQuan ^a   Qian, ZhiYong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Anaesthesia assay; Biodegradable; Controlled release; Sol gel sol transition; Thermosensitive hydrogel

Indexed keywords

ANESTHESIOLOGY; ANESTHETICS; HYDROGELS; MAGNETIC RESONANCE IMAGING; MOLECULES; PARTICLE SIZE; PARTICLE SIZE ANALYSIS; POLYETHYLENE GLYCOLS; SOL-GEL PROCESS; SOL-GELS; SOLUTIONS; TARGETED DRUG DELIVERY; TEMPERATURE;

ANESTHESIA ASSAY; BIODEGRADABLE; CONTROLLED RELEASE; DRUG-DELIVERY SYSTEMS; INJECTABLES; POLY(Ε CAPROLACTONE); SITU GEL FORMING; SOL-GEL-SOL TRANSITIONS; THERMO SENSITIVE; THERMO-SENSITIVE HYDROGEL;

CONTROLLED DRUG DELIVERY;

BOVINE SERUM ALBUMIN; CARBON 13; HONOKIOL; LIDOCAINE; MACROGOL; POLYCAPROLACTONE;

ANALYZER; ANIMAL EXPERIMENT; ANTINOCICEPTION; AQUEOUS SOLUTION; ARTICLE; BIODEGRADABILITY; BODY TEMPERATURE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG SYNTHESIS; ENVIRONMENTAL TEMPERATURE; GEL; HEAT SENSITIVITY; HYDROGEL; HYDROPHILICITY; HYDROPHOBICITY; IN VIVO STUDY; LASER DIFFRACTION; LOCAL ANESTHESIA; MACROMOLECULE; MOLECULAR MECHANICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; PHASE TRANSITION; PRIORITY JOURNAL; RAT; SUSTAINED DRUG RELEASE; TAIL FLICK TEST; TEMPERATURE DEPENDENCE;

EID: 70349980368     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2009.05.025     Document Type: Article

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