Thymoquinone attenuates Doxorubicin-induced nephrotoxicity in rats: Role of Nrf2 and NOX4

Chemico-Biological Interactions

Volumn 223, Issue , 2014, Pages 102-108

  Elsherbiny, Nehal M ^a   El Sherbiny, Mohamed ^b  

^a MANSOURA UNIVERSITY   (Egypt)

^b MANSOURA UNIVERSITY   (Egypt)

Author keywords

Doxorubicin; NADPH oxidase 4; Nephrotoxicity; Nuclear factor erythroid 2 related factor 2; Thymoquinone

Indexed keywords

ALBUMIN; CREATININE; DOXORUBICIN; GLUTATHIONE TRANSFERASE; INTERLEUKIN 10; INTERLEUKIN 6; MALONALDEHYDE; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SUPEROXIDE DISMUTASE; THYMOQUINONE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UREA; ANTINEOPLASTIC ANTIBIOTIC; BENZOQUINONE DERIVATIVE; NFE2L2 PROTEIN, RAT; NOX4 PROTEIN, RAT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; HISTOPATHOLOGY; KIDNEY INJURY; LIPID PEROXIDATION; MALE; NEPHROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN URINE LEVEL; RAT; RENAL PROTECTION; UREA BLOOD LEVEL; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; DRUG EFFECTS; GENETICS; KIDNEY; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT; UREA NITROGEN BLOOD LEVEL;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BENZOQUINONES; BLOOD UREA NITROGEN; CREATININE; DOXORUBICIN; GLUTATHIONE TRANSFERASE; KIDNEY; LIPID PEROXIDATION; MALE; NADPH OXIDASE; NF-E2-RELATED FACTOR 2; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SUPEROXIDE DISMUTASE;

EID: 84907940920     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.09.015     Document Type: Article

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