Thymoquinone induces heme oxygenase-1 expression in HaCaT cells via Nrf2/ARE activation: Akt and AMPKα as upstream targets

Food and Chemical Toxicology

Volumn 65, Issue , 2014, Pages 18-26

  Kundu, Juthika ^a   Kim, Do Hee ^b   Kundu, Joydeb Kumar ^a   Chun, Kyung Soo ^a  

^a Keimyung University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Akt; AMPK ; HaCaT cells; Heme oxygenase 1; Nrf2; Thymoquinone

Indexed keywords

ACETYLCYSTEINE; HEME OXYGENASE 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; THYMOQUINONE; TRANSCRIPTION FACTOR NRF2; AMP ACTIVATED PROTEIN KINASE ALPHA; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE ACTIVITY; GENE SILENCING; HUMAN; HUMAN CELL; KERATINOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; REPORTER GENE; HACAT CELL; INHIBITION KINETICS; SIGNAL TRANSDUCTION;

AKT; AMPKΑ; HACAT CELLS; HEME OXYGENASE-1; NRF2; THYMOQUINONE;

ADENYLATE KINASE; BASE SEQUENCE; BENZOQUINONES; CELL LINE; DNA PRIMERS; ENZYME ACTIVATION; HEME OXYGENASE-1; HUMANS; NF-E2-RELATED FACTOR 2; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84891686756     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.12.015     Document Type: Article

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