FK506 alleviates proteinuria in rats with adriamycin-induced nephropathy by down-regulating TRPC6 and CaN expression

Journal of Nephrology

Volumn 25, Issue 6, 2012, Pages 918-925

  Liu, Yaqing ^a   Ji, Zequan ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Calcineurin; Nephrotic syndrome; Tacrolimus; TRPC6

Indexed keywords

CALCINEURIN; DOXORUBICIN; MESSENGER RNA; TACROLIMUS; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLOOD SAMPLING; CONTROLLED STUDY; DISEASE ACTIVITY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; IMMUNOHISTOCHEMISTRY; KIDNEY DISEASE; LOW DRUG DOSE; MALE; MOLECULAR PATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEINURIA; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVIEW; RNA SEQUENCE; SEQUENCE ANALYSIS; UPREGULATION; URINALYSIS; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CALCINEURIN; CYTOPROTECTION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DOXORUBICIN; ENZYME INHIBITORS; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY DISEASES; MALE; PROTEINURIA; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TACROLIMUS; TIME FACTORS; TRPC CATION CHANNELS;

EID: 84870601744     PISSN: 11218428     EISSN: 17246059     Source Type: Journal    
DOI: 10.5301/jn.5000192     Document Type: Review

References (12)

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