Huangkui capsule, an extract from Abelmoschus manihot (L.) medic, ameliorates adriamycin-induced renal inflammation and glomerular injury via inhibiting p38MAPK signaling pathway activity in rats

Journal of Ethnopharmacology

Volumn 147, Issue 2, 2013, Pages 311-320

  Tu, Yue ^a,b   Sun, Wei ^b   Wan, Yi Gang ^c   Che, Xiao Yan ^c   Pu, Hong Ping ^c   Yin, Xue Jiao ^b   Chen, Hao Li ^a   Meng, Xian Jie ^a   Huang, Yan Ru ^a   Shi, Xi Miao ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b AFFILIATED HOSPITAL OF NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Adriamycin induced nephropathy; Glomerular injury; Huangkui capsule; p38 mitogen activated protein kinase signaling pathway; Phosphorylated p38 mitogen activated protein kinase; Renal inflammation

Indexed keywords

DOXORUBICIN; HUANGKUI CAPSULE; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE 14; PLANT EXTRACT; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ABELMOSCHUS MANIHOT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CELL INFILTRATION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; GLOMERULAR INJURY; GLOMERULAR LESION; KIDNEY FUNCTION; KIDNEY INJURY; MACROPHAGE; MEDICINAL PLANT; NEPHRECTOMY; NEPHRITIS; NONHUMAN; PODOCYTE; PROTEIN EXPRESSION; PROTEINURIA; RAT; SHAM PROCEDURE; SIGNAL TRANSDUCTION;

ABELMOSCHUS; ANIMALS; CAPSULES; DOXORUBICIN; DRUGS, CHINESE HERBAL; FEMALE; INTERLEUKIN-2; KIDNEY DISEASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA;

ABELMOSCHUS MANIHOT; RATTUS;

EID: 84876916833     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.03.006     Document Type: Article

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