Nrf2 deficiency exaggerates doxorubicin-induced cardiotoxicity and cardiac dysfunction

Oxidative Medicine and Cellular Longevity

Volumn 2014, Issue , 2014, Pages

  Li, Siying ^a,b   Wang, Wenjuan ^a,b   Niu, Ting ^a   Wang, Hui ^a,b   Li, Bin ^a,b   Shao, Lei ^a,b   Lai, Yimu ^b   Li, Huanjie ^a   Janicki, Joseph S ^b   Wang, Xing Li ^a   Tang, Dongqi ^a,b   Cui, Taixing ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLOGY; MAMMALS; OXIDATIVE STRESS; PROTEINS;

ANTI-CANCER THERAPIES; CULTURED CARDIOMYOCYTES; INTRAPERITONEAL INJECTIONS; NUCLEAR FACTORS; OVER-EXPRESSION; PROTEIN AGGREGATES; RELATED FACTORS; UBIQUITINATED PROTEINS;

AGGREGATES;

AUTOPHAGY PROTEIN 5; CATHEPSIN D; DOXORUBICIN; HEME OXYGENASE 1; MICROTUBULE ASSOCIATED PROTEIN 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2; UBIQUITINATED PROTEIN; ATG5 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; NFE2L2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CARDIOMYOPATHY; CARDIOTOXICITY; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; CYTOPLASM; DIASTOLE; DRUG CYTOTOXICITY; ECHOCARDIOGRAPH; ECHOCARDIOGRAPHY; GENE OVEREXPRESSION; HEART DISEASE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART OUTPUT; LYSOSOME MEMBRANE; MACROAUTOPHAGY; MACROMOLECULE; MALE; MEMBRANE STRUCTURE; MOUSE; NECROSIS; NONHUMAN; OXIDATIVE STRESS; PROTEIN DEFICIENCY; SYSTOLE; TRANSCRIPTION FACTOR NRF2 DEFICIENCY; UBIQUITINATION; UPREGULATION; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; DRUG EFFECTS; GENETICS; HEART; HEART MUSCLE; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; TOXICITY;

ANIMALS; AUTOPHAGY; CARDIOMYOPATHIES; CARDIOTOXICITY; CELLS, CULTURED; DOXORUBICIN; HEART; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MYOCARDIUM; MYOCYTES, CARDIAC; NECROSIS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS;

EID: 84901916253     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2014/748524     Document Type: Article

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