Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the nuclear factor erythroid 2-related factor 2 pathway

Journal of Pharmacology and Experimental Therapeutics

Volumn 342, Issue 1, 2012, Pages 81-90

  He, Xiaoqing ^a   Wang, Liping ^b,c   Szklarz, Grazyna ^b   Bi, Yongyi ^c   Ma, Qiang ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

^c WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; PARAQUAT; REACTIVE OXYGEN METABOLITE; RESVERATROL; TRANSCRIPTION FACTOR NRF2; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BRONCHUS MUCOSA; CELL DEATH; CELL PROTECTION; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG EFFECT; EMBRYO; EPITHELIUM CELL; FIBROSIS; GENE INACTIVATION; GENE INDUCTION; GENE SILENCING; HUMAN; HUMAN CELL; INFLAMMATION; LUNG FIBROBLAST; MOUSE; MYOFIBROBLAST; NONHUMAN; OXIDATIVE STRESS; PARAQUAT POISONING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL DEATH; CELLS, CULTURED; CYTOPROTECTION; EPITHELIAL CELLS; FIBROBLASTS; HUMANS; INFLAMMATION; INTERLEUKIN-6; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MYOFIBROBLASTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PARAQUAT; REACTIVE OXYGEN SPECIES; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; STILBENES; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84862506060     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.194142     Document Type: Article

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