Doxorubicin Induces Cytotoxicity through Upregulation of pERK-Dependent ATF3

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Park, Eun Jung ^a   Kwon, Hyuk Kwon ^a   Choi, Yong Min ^a   Shin, Hyeon Jun ^a   Choi, Sangdun ^a  

^a Ajou University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOXORUBICIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; EMBRYO; ENZYME ACTIVITY; ENZYME INDUCTION; FIBROBLAST; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; TRANSCRIPTION REGULATION; UPREGULATION;

ACTIVATING TRANSCRIPTION FACTOR 3; ANIMALS; CELL CYCLE; CELL DEATH; CELL LINE; CELL PROLIFERATION; DOXORUBICIN; EMBRYO, MAMMALIAN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GENE SILENCING; HUMANS; INTERLEUKIN-6; KIDNEY TUBULES, PROXIMAL; MICE; MICE, KNOCKOUT; NITRIC OXIDE; PHOSPHORYLATION; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84866371596     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044990     Document Type: Article

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