메뉴 건너뛰기




Volumn 20, Issue 3, 2014, Pages 417-431

Interaction of inducible nitric oxide synthase with Rac2 regulates reactive oxygen and nitrogen species generation in the human neutrophil phagosomes: Implication in microbial killing

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; BOVINE SERUM ALBUMIN; ELASTASE; GELATINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MYELOPEROXIDASE; NITRIC OXIDE; RAC2 PROTEIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

EID: 84892562419     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2012.4970     Document Type: Article
Times cited : (58)

References (68)
  • 2
    • 0033105874 scopus 로고    scopus 로고
    • NADPH oxidase: An update
    • Babior BM. NADPH oxidase: an update. Blood 93: 1464-1476, 1999. (Pubitemid 29102471)
    • (1999) Blood , vol.93 , Issue.5 , pp. 1464-1476
    • Babior, B.M.1
  • 3
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman JS, Beckman TW, Chen J, Marshall PA, and Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 87: 1620-1624, 1990.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 4
    • 0027280338 scopus 로고
    • Pathological implications of nitric oxide, superoxide and peroxynitrite formation
    • Beckman JS and Crow JP. Pathological implications of nitric oxide, superoxide and peroxynitrite formation. Biochem Soc Trans 21: 330-334, 1993. (Pubitemid 23167917)
    • (1993) Biochemical Society Transactions , vol.21 , Issue.2 , pp. 330-334
    • Beckman, J.S.1    Crow, J.P.2
  • 5
    • 0032573378 scopus 로고    scopus 로고
    • Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases
    • Caron E and Hall A. Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science 282: 1717-1721, 1998. (Pubitemid 28549289)
    • (1998) Science , vol.282 , Issue.5394 , pp. 1717-1721
    • Caron, E.1    Hall, A.2
  • 6
    • 0242330233 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase (NOS II) is constitutive in human neutrophils
    • DOI 10.1034/j.1600-0463.2003.1111008.x
    • Cedergren J, Follin P, Forslund T, Lindmark M, Sundqvist T, and Skogh T. Inducible nitric oxide synthase (NOS II) is constitutive in human neutrophils. Apmis 111: 963-968, 2003. (Pubitemid 37352615)
    • (2003) APMIS , vol.111 , Issue.10 , pp. 963-968
    • Cedergren, J.1    Follin, P.2    Forslund, T.3    Lindmark, M.4    Sundqvist, T.5    Skogh, T.6
  • 7
    • 0025259712 scopus 로고
    • Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation
    • Clark RA, Volpp BD, Leidal KG, and Nauseef WM. Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation. J Clin Invest 85: 714-721, 1990. (Pubitemid 20087473)
    • (1990) Journal of Clinical Investigation , vol.85 , Issue.3 , pp. 714-721
    • Clark, R.A.1    Volpp, B.D.2    Leidal, K.G.3    Nauseef, W.M.4
  • 8
    • 0030684003 scopus 로고    scopus 로고
    • Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes
    • DOI 10.1084/jem.186.9.1487
    • Cox D, Chang P, Zhang Q, Reddy PG, Bokoch GM, and Greenberg S. Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes. J Exp Med 186: 1487-1494, 1997. (Pubitemid 27479808)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.9 , pp. 1487-1494
    • Cox, D.1    Chang, P.2    Zhang, Q.3    Reddy, P.G.4    Bokoch, G.M.5    Greenberg, S.6
  • 9
    • 0032741371 scopus 로고    scopus 로고
    • NADPH oxidase activation and assembly during phagocytosis
    • DeLeo FR, Allen LA, Apicella M, and Nauseef WM. NADPH oxidase activation and assembly during phagocytosis. J Immunol 163: 6732-6740, 1999.
    • (1999) J Immunol , vol.163 , pp. 6732-6740
    • Deleo, F.R.1    Allen, L.A.2    Apicella, M.3    Nauseef, W.M.4
  • 11
    • 0027377685 scopus 로고
    • Pulmonary thromboembolism-induced alterations in nitric oxide release from rat circulating neutrophils
    • Dikshit M, Kumari R, and Srimal RC. Pulmonary thromboembolism-induced alterations in nitric oxide release from rat circulating neutrophils. J Pharmacol Exp Ther 265: 1369-1373, 1993. (Pubitemid 23321043)
    • (1993) Journal of Pharmacology and Experimental Therapeutics , vol.265 , Issue.3 , pp. 1369-1373
    • Dikshit, M.1    Kumari, R.2    Srimal, R.C.3
  • 12
    • 0019452317 scopus 로고
    • Quantitation of neutrophil phagocytosis, using fluorescent latex beads. Correlation of microscopy and flow cytometry
    • Dunn PA and Tyrer HW. Quantitation of neutrophil phagocytosis, using fluorescent latex beads. Correlation of microscopy and flow cytometry. J Lab Clin Med 98: 374-381, 1981. (Pubitemid 11049469)
    • (1981) Journal of Laboratory and Clinical Medicine , vol.98 , Issue.3 , pp. 374-381
    • Dunn, P.A.1    Tyrer, H.W.2
  • 14
    • 0026467074 scopus 로고
    • Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases
    • Farrell AJ, Blake DR, Palmer RM, and Moncada S. Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases. Ann Rheum Dis 51: 1219-1222, 1992.
    • (1992) Ann Rheum Dis , vol.51 , pp. 1219-1222
    • Farrell, A.J.1    Blake, D.R.2    Palmer, R.M.3    Moncada, S.4
  • 16
    • 0346100664 scopus 로고    scopus 로고
    • Activation of Rac2 and Cdc42 on Fc and complement receptor ligation in human neutrophils
    • DOI 10.1189/jlb.1102525
    • Forsberg M, Druid P, Zheng L, Stendahl O, and Sarndahl E. Activation of Rac2 and Cdc42 on Fc and complement receptor ligation in human neutrophils. J Leukoc Biol 74: 611-619, 2003. (Pubitemid 38040389)
    • (2003) Journal of Leukocyte Biology , vol.74 , Issue.4 , pp. 611-619
    • Forsberg, M.1    Druid, P.2    Zheng, L.3    Stendahl, O.4    Sarndahl, E.5
  • 18
    • 0037108899 scopus 로고    scopus 로고
    • Protein nitration is predominantly mediated by a peroxynitrite-dependent pathway in cultured human leucocytes
    • DOI 10.1042/BJ20020825
    • Galinanes M and Matata BM. Protein nitration is predominantly mediated by a peroxynitrite-dependent pathway in cultured human leucocytes. Biochem J 367: 467-473, 2002. (Pubitemid 35216821)
    • (2002) Biochemical Journal , vol.367 , Issue.2 , pp. 467-473
    • Galinanes, M.1    Matata, B.M.2
  • 21
    • 0032213375 scopus 로고    scopus 로고
    • Inside the neutrophil phagosome: Oxidants, myeloperoxidase, and bacterial killing
    • Hampton MB, Kettle AJ, and Winterbourn CC. Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing. Blood 92: 3007-3017, 1998. (Pubitemid 28492304)
    • (1998) Blood , vol.92 , Issue.9 , pp. 3007-3017
    • Hampton, M.B.1    Kettle, A.J.2    Winterbourn, C.C.3
  • 22
    • 0030052434 scopus 로고    scopus 로고
    • Effect of nitric oxide on staphylococcal killing and interactive effect with superoxide
    • Kaplan SS, Lancaster JR, Jr., Basford RE, and Simmons RL. Effect of nitric oxide on staphylococcal killing and interactive effect with superoxide. Infect Immun 64: 69-76, 1996. (Pubitemid 26009343)
    • (1996) Infection and Immunity , vol.64 , Issue.1 , pp. 69-76
    • Kaplan, S.S.1    Lancaster Jr., J.R.2    Basford, R.E.3    Simmons, R.L.4
  • 23
    • 18244390487 scopus 로고    scopus 로고
    • Myeloperoxidase: Friend and foe
    • DOI 10.1189/jlb.1204697
    • Klebanoff SJ. Myeloperoxidase: friend and foe. J Leukoc Biol 77: 598-625, 2005. (Pubitemid 40628741)
    • (2005) Journal of Leukocyte Biology , vol.77 , Issue.5 , pp. 598-625
    • Klebanoff, S.J.1
  • 25
    • 0025324372 scopus 로고
    • Selective down-regulation of alveolar macrophage oxidative response to opsonin-independent phagocytosis
    • Kobzik L, Godleski JJ, and Brain JD. Selective down-regulation of alveolar macrophage oxidative response to opsoninindependent phagocytosis. J Immunol 144: 4312-4319, 1990. (Pubitemid 20187774)
    • (1990) Journal of Immunology , vol.144 , Issue.11 , pp. 4312-4319
    • Kobzik, L.1    Godleski, J.J.2    Brain, J.D.3
  • 26
    • 76049118697 scopus 로고    scopus 로고
    • Cdk2 nitrosylation and loss of mitochondrial potential mediate NO-dependent biphasic effect on HL-60 cell cycle
    • Kumar S, Barthwal MK, and Dikshit M. Cdk2 nitrosylation and loss of mitochondrial potential mediate NO-dependent biphasic effect on HL-60 cell cycle. Free Radic Biol Med 48: 851-861, 2010.
    • (2010) Free Radic Biol Med , vol.48 , pp. 851-861
    • Kumar, S.1    Barthwal, M.K.2    Dikshit, M.3
  • 27
    • 77951171787 scopus 로고    scopus 로고
    • Functional and molecular characterization of NOS isoforms in rat neutrophil precursor cells
    • Kumar S, Jyoti A, Keshari RS, Singh M, Barthwal MK, and Dikshit M. Functional and molecular characterization of NOS isoforms in rat neutrophil precursor cells. Cytometry A 77: 467-477, 2010.
    • (2010) Cytometry A , vol.77 , pp. 467-477
    • Kumar, S.1    Jyoti, A.2    Keshari, R.S.3    Singh, M.4    Barthwal, M.K.5    Dikshit, M.6
  • 28
    • 0034890090 scopus 로고    scopus 로고
    • Specific association of nitric oxide synthase-2 with Rac isoforms in activated murine macrophages
    • Kuncewicz T, Balakrishnan P, Snuggs MB, and Kone BC. Specific association of nitric oxide synthase-2 with Rac isoforms in activated murine macrophages. Am J Physiol Renal Physiol 281: F326-F336, 2001.
    • (2001) Am J Physiol Renal Physiol , vol.281
    • Kuncewicz, T.1    Balakrishnan, P.2    Snuggs, M.B.3    Kone, B.C.4
  • 29
    • 0036303064 scopus 로고    scopus 로고
    • Nitration/S-nitrosation of protein by peroxynitrite-treatment and subsequent modification by glutathione S-transferase and glutathione peroxidase
    • DOI 10.1023/A:1015510207489
    • Kuo WN and Kocis JM. Nitration/S-nitrosation of proteins by peroxynitrite-treatment and subsequent modification by glutathione S-transferase and glutathione peroxidase. Mol Cell Biochem 233: 57-63, 2002. (Pubitemid 34746110)
    • (2002) Molecular and Cellular Biochemistry , vol.233 , Issue.1-2 , pp. 57-63
    • Kuo, W.-N.1    Kocis, J.M.2
  • 31
    • 0030590652 scopus 로고    scopus 로고
    • Flow cytometric identification of murine neutrophils and monocytes
    • DOI 10.1016/0022-1759(96)00138-X
    • Lagasse E and Weissman IL. Flow cytometric identification of murine neutrophils and monocytes. J Immunol Methods 197: 139-150, 1996. (Pubitemid 26342018)
    • (1996) Journal of Immunological Methods , vol.197 , Issue.1-2 , pp. 139-150
    • Lagasse, E.1    Weissman, I.L.2
  • 32
    • 0034671713 scopus 로고    scopus 로고
    • Biphasic regulation of leukocyte superoxide generation by nitric oxide and peroxynitrite
    • DOI 10.1074/jbc.M006341200
    • Lee C, Miura K, Liu X, and Zweier JL. Biphasic regulation of leukocyte superoxide generation by nitric oxide and peroxynitrite. J Biol Chem 275: 38965-38972, 2000. (Pubitemid 32058907)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.50 , pp. 38965-38972
    • Lee, C.-I.1    Miura, K.2    Liu, X.3    Zweier, J.L.4
  • 33
    • 0030008394 scopus 로고    scopus 로고
    • Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions
    • Lowell CA, Fumagalli L, and Berton G. Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions. J Cell Biol 133: 895-910, 1996.
    • (1996) J Cell Biol , vol.133 , pp. 895-910
    • Lowell, C.A.1    Fumagalli, L.2    Berton, G.3
  • 34
    • 0030937832 scopus 로고    scopus 로고
    • Nitric oxide and macrophage function
    • DOI 10.1146/annurev.immunol.15.1.323
    • MacMicking J, Xie QW, and Nathan C. Nitric oxide and macrophage function. Annu Rev Immunol 15: 323-350, 1997. (Pubitemid 27169284)
    • (1997) Annual Review of Immunology , vol.15 , pp. 323-350
    • MacMicking, J.1    Xie, Q.-W.2    Nathan, C.3
  • 36
    • 0026700522 scopus 로고
    • Evidence for reactive nitrogen intermediates in killing of staphylococci by human neutrophil cytoplasts. A new microbicidal pathway for polymorphonuclear leukocytes
    • Malawista SE, Montgomery RR, and van Blaricom G. Evidence for reactive nitrogen intermediates in killing of staphylococci by human neutrophil cytoplasts. A new microbicidal pathway for polymorphonuclear leukocytes. J Clin Invest 90: 631-636, 1992.
    • (1992) J Clin Invest , vol.90 , pp. 631-636
    • Malawista, S.E.1    Montgomery, R.R.2    Van Blaricom, G.3
  • 37
    • 46749101053 scopus 로고    scopus 로고
    • Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNgamma-dependent iNOS expression in the vasculature of healthy mice
    • Morton J, Coles B, Wright K, Gallimore A, Morrow JD, Terry ES, Anning PB, Morgan BP, Dioszeghy V, Kuhn H, et al. Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNgamma-dependent iNOS expression in the vasculature of healthy mice. Blood 111: 5187-5194, 2008.
    • (2008) Blood , vol.111 , pp. 5187-5194
    • Morton, J.1    Coles, B.2    Wright, K.3    Gallimore, A.4    Morrow, J.D.5    Terry, E.S.6    Anning, P.B.7    Morgan, B.P.8    Dioszeghy, V.9    Kuhn, H.10
  • 39
    • 33344468233 scopus 로고    scopus 로고
    • Neutrophils and immunity: Challenges and opportunities
    • DOI 10.1038/nri1785
    • Nathan C. Neutrophils and immunity: challenges and opportunities. Nat Rev Immunol 6: 173-182, 2006. (Pubitemid 43290987)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.3 , pp. 173-182
    • Nathan, C.1
  • 42
    • 67650170329 scopus 로고    scopus 로고
    • Ion channel modulators mediated alterations in NO-induced free radical generation and neutrophil membrane potential
    • Patel S, Vemula J, Konikkat S, Barthwal MK, and Dikshit M. Ion channel modulators mediated alterations in NO-induced free radical generation and neutrophil membrane potential. Free Radic Res 43: 514-521, 2009.
    • (2009) Free Radic Res , vol.43 , pp. 514-521
    • Patel, S.1    Vemula, J.2    Konikkat, S.3    Barthwal, M.K.4    Dikshit, M.5
  • 43
    • 0037087512 scopus 로고    scopus 로고
    • Rab5a GTPase regulates fusion between pathogen-containing phagosomes and cytoplasmic organelles in human neutrophils
    • Perskvist N, Roberg K, Kulyte A, and Stendahl O. Rab5a GTPase regulates fusion between pathogen-containing phagosomes and cytoplasmic organelles in human neutrophils. J Cell Sci 115: 1321-1330, 2002. (Pubitemid 34272496)
    • (2002) Journal of Cell Science , vol.115 , Issue.6 , pp. 1321-1330
    • Perskvist, N.1    Roberg, K.2    Kulyte, A.3    Stendahl, O.4
  • 44
    • 0028304791 scopus 로고
    • Stimulatory and inhibitory action of nitric oxide donor agents vs nitrovasodilators on reactive oxygen production by isolated polymorphonuclear leukocytes
    • Pieper GM, Clarke GA, and Gross GJ. Stimulatory and inhibitory action of nitric oxide donor agents vs. nitrovasodilators on reactive oxygen production by isolated polymorphonuclear leukocytes. J Pharmacol Exp Ther 269: 451-456, 1994. (Pubitemid 24157306)
    • (1994) Journal of Pharmacology and Experimental Therapeutics , vol.269 , Issue.2 , pp. 451-456
    • Pieper, G.M.1    Clarke, G.A.2    Gross, G.J.3
  • 45
    • 0041315633 scopus 로고    scopus 로고
    • Complexity of inducible nitric oxide synthase: Cellular source determines benefit versus toxicity
    • DOI 10.1161/01.CIR.0000086321.04702.AC
    • Poon BY, Raharjo E, Patel KD, Tavener S, and Kubes P. Complexity of inducible nitric oxide synthase: cellular source determines benefit versus toxicity. Circulation 108: 1107-1112, 2003. (Pubitemid 37071522)
    • (2003) Circulation , vol.108 , Issue.9 , pp. 1107-1112
    • Poon, B.Y.1    Raharjo, E.2    Patel, K.D.3    Tavener, S.4    Kubes, P.5
  • 46
    • 0035124194 scopus 로고    scopus 로고
    • Increased nitrite and nitrate concentrations in sera and urine of patients with cholera or shigellosis
    • Rabbani GH, Islam S, Chowdhury AK, Mitra AK, Miller MJ, and Fuchs G. Increased nitrite and nitrate concentrations in sera and urine of patients with cholera or shigellosis. Am J Gastroenterol 96: 467-472, 2001.
    • (2001) Am J Gastroenterol , vol.96 , pp. 467-472
    • Rabbani, G.H.1    Islam, S.2    Chowdhury, A.K.3    Mitra, A.K.4    Miller, M.J.5    Fuchs, G.6
  • 48
    • 0014200503 scopus 로고
    • Oxidation of NADPH by polymorphonuclear leucocytes during phagocytosis
    • Roberts J and Camacho Z. Oxidation of NADPH by polymorphonuclear leucocytes during phagocytosis. Nature 216: 606-607, 1967.
    • (1967) Nature , vol.216 , pp. 606-607
    • Roberts, J.1    Camacho, Z.2
  • 49
    • 0030822858 scopus 로고    scopus 로고
    • Regulation of inducible nitric oxide synthase and nitric oxide during hepatic injury and fibrogenesis
    • Rockey DC and Chung JJ. Regulation of inducible nitric oxide synthase and nitric oxide during hepatic injury and fibrogenesis. Am J Physiol 273: G124-G130, 1997.
    • (1997) Am J Physiol , vol.273
    • Rockey, D.C.1    Chung, J.J.2
  • 52
    • 80051789882 scopus 로고    scopus 로고
    • Molecular and biochemical characterization of nitric oxide synthase isoforms and their intracellular distribution in human peripheral blood mononuclear cells
    • Saluja R, Jyoti A, Chatterjee M, Habib S, Verma A, Mitra K, Barthwal MK, Bajpai VK, and Dikshit M. Molecular and biochemical characterization of nitric oxide synthase isoforms and their intracellular distribution in human peripheral blood mononuclear cells. Biochim Biophys Acta 1813: 1700-1707, 2011.
    • (2011) Biochim Biophys Acta , vol.1813 , pp. 1700-1707
    • Saluja, R.1    Jyoti, A.2    Chatterjee, M.3    Habib, S.4    Verma, A.5    Mitra, K.6    Barthwal, M.K.7    Bajpai, V.K.8    Dikshit, M.9
  • 54
    • 0034324949 scopus 로고    scopus 로고
    • Modulation of polymorphonuclear leukocytes function by nitric oxide
    • Sethi S and Dikshit M. Modulation of polymorphonuclear leukocytes function by nitric oxide. Thromb Res 100: 223-247, 2000.
    • (2000) Thromb Res , vol.100 , pp. 223-247
    • Sethi, S.1    Dikshit, M.2
  • 55
    • 0032931980 scopus 로고    scopus 로고
    • Nitric oxide-mediated augmentation of polymorphonuclear free radical generation after hypoxia-reoxygenation
    • Sethi S, Singh MP, and Dikshit M. Nitric oxide-mediated augmentation of polymorphonuclear free radical generation after hypoxia-reoxygenation. Blood 93: 333-340, 1999. (Pubitemid 29019420)
    • (1999) Blood , vol.93 , Issue.1 , pp. 333-340
    • Sethi, S.1    Singh, M.P.2    Dikshit, M.3
  • 56
    • 2642568618 scopus 로고    scopus 로고
    • Ascorbate-mediated enhancement of reactive oxygen species generation from polymorphonuclear leukocytes: Modulatory effect of nitric oxide
    • DOI 10.1189/jlb.0903415
    • Sharma P, Raghavan SA, Saini R, and Dikshit M. Ascorbatemediated enhancement of reactive oxygen species generation from polymorphonuclear leukocytes: modulatory effect of nitric oxide. J Leukoc Biol 75: 1070-1078, 2004. (Pubitemid 38720649)
    • (2004) Journal of Leukocyte Biology , vol.75 , Issue.6 , pp. 1070-1078
    • Sharma, P.1    Raghavan, S.A.V.2    Saini, R.3    Dikshit, M.4
  • 60
    • 34247470765 scopus 로고    scopus 로고
    • Effect of nitric oxide on phagocytic activity of lipopolysaccharide- induced macrophages: Possible role of exogenous l-arginine
    • DOI 10.1016/j.cellbi.2006.11.029, PII S1065699506002952
    • Tumer C, Bilgin HM, Obay BD, Diken H, Atmaca M, and Kelle M. Effect of nitric oxide on phagocytic activity of lipopolysaccharide-induced macrophages: possible role of exogenous L-arginine. Cell Biol Int 31: 565-569, 2007. (Pubitemid 46660643)
    • (2007) Cell Biology International , vol.31 , Issue.6 , pp. 565-569
    • Tumer, C.1    Bilgin, H.M.2    Obay, B.D.3    Diken, H.4    Atmaca, M.5    Kelle, M.6
  • 61
    • 77954143681 scopus 로고    scopus 로고
    • Subcellular and cellular locations of nitric oxide synthase isoforms as determinants of health and disease
    • Villanueva C and Giulivi C. Subcellular and cellular locations of nitric oxide synthase isoforms as determinants of health and disease. Free Radic Biol Med 49: 307-316, 2010.
    • (2010) Free Radic Biol Med , vol.49 , pp. 307-316
    • Villanueva, C.1    Giulivi, C.2
  • 65
    • 0029900905 scopus 로고    scopus 로고
    • Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury
    • Xia Y, Dawson VL, Dawson TM, Snyder SH, and Zweier JL. Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury. Proc Natl Acad Sci USA 93: 6770-6774, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6770-6774
    • Xia, Y.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4    Zweier, J.L.5
  • 66
    • 0032575598 scopus 로고    scopus 로고
    • Inducible nitric-oxide synthase generates superoxide from the reductase domain
    • DOI 10.1074/jbc.273.35.22635
    • Xia Y, Roman LJ, Masters BS, and Zweier JL. Inducible nitric-oxide synthase generates superoxide from the reductase domain. J Biol Chem 273: 22635-22639, 1998. (Pubitemid 28399833)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.35 , pp. 22635-22639
    • Xia, Y.1    Roman, L.J.2    Masters, B.S.S.3    Zweier, J.L.4
  • 68
    • 8444239999 scopus 로고    scopus 로고
    • Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles
    • Yamauchi A, Kim C, Li S, Marchal CC, Towe J, Atkinson SJ, and Dinauer MC. Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles. J Immunol 173: 5971-5979, 2004. (Pubitemid 39487751)
    • (2004) Journal of Immunology , vol.173 , Issue.10 , pp. 5971-5979
    • Yamauchi, A.1    Kim, C.2    Li, S.3    Marchal, C.C.4    Towe, J.5    Atkinson, S.J.6    Dinauer, M.C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.