-
1
-
-
85135661443
-
Ecobiology and geographical distribution of potentially toxic marine dinoflagellates
-
CRC Press, Boca Raton, L.M. Botana (Ed.)
-
Vlamis A., Katikou P. Ecobiology and geographical distribution of potentially toxic marine dinoflagellates. Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection 2014, 569-625. CRC Press, Boca Raton. third ed. L.M. Botana (Ed.).
-
(2014)
Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection
, pp. 569-625
-
-
Vlamis, A.1
Katikou, P.2
-
2
-
-
24344502293
-
Diarrhetic shellfish poisoning by okadaic acid esters from Brown crabs (Cancer pagurus) in Norway
-
Torgersen T., Aasen J., Aune T. Diarrhetic shellfish poisoning by okadaic acid esters from Brown crabs (Cancer pagurus) in Norway. Toxicon 2005, 46(5):572-578.
-
(2005)
Toxicon
, vol.46
, Issue.5
, pp. 572-578
-
-
Torgersen, T.1
Aasen, J.2
Aune, T.3
-
3
-
-
84877947301
-
Current situation on analysis of marine toxins
-
Botana A.M., et al. Current situation on analysis of marine toxins. Rev. Anal. Chem. 2012, 32(1):15-34.
-
(2012)
Rev. Anal. Chem.
, vol.32
, Issue.1
, pp. 15-34
-
-
Botana, A.M.1
-
4
-
-
84907525395
-
Dinoflagellate toxins: an overview
-
CRC Press, Boca Ratón, L.M. Botana (Ed.)
-
Holmes M.J., Brust A., Lewis R.J. Dinoflagellate toxins: an overview. Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection 2014, 3-38. CRC Press, Boca Ratón. L.M. Botana (Ed.).
-
(2014)
Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection
, pp. 3-38
-
-
Holmes, M.J.1
Brust, A.2
Lewis, R.J.3
-
5
-
-
84891908251
-
Simultaneous effect of temperature and irradiance on growth and okadaic acid production from the marine dinoflagellate Prorocentrum belizeanum
-
Lopez-Rosales L., et al. Simultaneous effect of temperature and irradiance on growth and okadaic acid production from the marine dinoflagellate Prorocentrum belizeanum. Toxins (Basel) 2014, 6(1):229-253.
-
(2014)
Toxins (Basel)
, vol.6
, Issue.1
, pp. 229-253
-
-
Lopez-Rosales, L.1
-
6
-
-
0025818494
-
Strain dependent production of ciguatoxin precursors (gambiertoxins) by Gambierdiscus toxicus (Dinophyceae) in culture
-
Holmes M.J., et al. Strain dependent production of ciguatoxin precursors (gambiertoxins) by Gambierdiscus toxicus (Dinophyceae) in culture. Toxicon 1991, 29(6):761-775.
-
(1991)
Toxicon
, vol.29
, Issue.6
, pp. 761-775
-
-
Holmes, M.J.1
-
7
-
-
77951095530
-
Effects of environmental regimens on the toxin profile of Alexandrium ostenfeldii
-
Otero P., et al. Effects of environmental regimens on the toxin profile of Alexandrium ostenfeldii. Environ. Toxicol. Chem. 2010, 29(2):301-310.
-
(2010)
Environ. Toxicol. Chem.
, vol.29
, Issue.2
, pp. 301-310
-
-
Otero, P.1
-
8
-
-
84878319357
-
Influence of environmental factors on the paralytic shellfish toxin content and profile of Alexandrium catenella (Dinophyceae) isolated from the Mediterranean Sea
-
Laabir M., et al. Influence of environmental factors on the paralytic shellfish toxin content and profile of Alexandrium catenella (Dinophyceae) isolated from the Mediterranean Sea. Mar. Drugs 2013, 11(5):1583-1601.
-
(2013)
Mar. Drugs
, vol.11
, Issue.5
, pp. 1583-1601
-
-
Laabir, M.1
-
9
-
-
0034122087
-
The structure elucidation and biological activities of high molecular weight algal toxins: maitotoxin, prymnesins and zooxanthellatoxins
-
Murata M., Yasumoto T. The structure elucidation and biological activities of high molecular weight algal toxins: maitotoxin, prymnesins and zooxanthellatoxins. Nat. Prod. Rep. 2000, 17(3):293-314.
-
(2000)
Nat. Prod. Rep.
, vol.17
, Issue.3
, pp. 293-314
-
-
Murata, M.1
Yasumoto, T.2
-
10
-
-
38349052082
-
Putative palytoxin and its new analogue, ovatoxin-a, in Ostreopsis ovata collected along the Ligurian coasts during the 2006 toxic outbreak
-
Ciminiello P., et al. Putative palytoxin and its new analogue, ovatoxin-a, in Ostreopsis ovata collected along the Ligurian coasts during the 2006 toxic outbreak. J. Am. Soc. Mass Spectrom. 2008, 19(1):111-120.
-
(2008)
J. Am. Soc. Mass Spectrom.
, vol.19
, Issue.1
, pp. 111-120
-
-
Ciminiello, P.1
-
11
-
-
53249152133
-
The continuing saga of the marine polyether biotoxins
-
Nicolaou K.C., Frederick M.O., Aversa R.J. The continuing saga of the marine polyether biotoxins. Angew. Chem. 2008, 47(38):7182-7225.
-
(2008)
Angew. Chem.
, vol.47
, Issue.38
, pp. 7182-7225
-
-
Nicolaou, K.C.1
Frederick, M.O.2
Aversa, R.J.3
-
12
-
-
84928960613
-
Measurement of algal toxins in the environment
-
John Willey & Sons Ltd., Chichester, R.A. Meyers (Ed.) Encyclopedia of Analytical Chemistry
-
Botana L.M., et al. Measurement of algal toxins in the environment. Environment: Water and Waste 2011, Volume S1:268-291. John Willey & Sons Ltd., Chichester. R.A. Meyers (Ed.).
-
(2011)
Environment: Water and Waste
, vol.S1
, pp. 268-291
-
-
Botana, L.M.1
-
13
-
-
0017893572
-
Binding to saxitoxin to electrically excitable neuroblastoma cells
-
Catterall W.A., Morrow C.S. Binding to saxitoxin to electrically excitable neuroblastoma cells. Proc. Natl. Acad. Sci. U.S.A. 1978, 75(1):218-222.
-
(1978)
Proc. Natl. Acad. Sci. U.S.A.
, vol.75
, Issue.1
, pp. 218-222
-
-
Catterall, W.A.1
Morrow, C.S.2
-
14
-
-
79960621367
-
The crystal structure of a voltage-gated sodium channel
-
Payandeh J., et al. The crystal structure of a voltage-gated sodium channel. Nature 2011, 475(7356):353-358.
-
(2011)
Nature
, vol.475
, Issue.7356
, pp. 353-358
-
-
Payandeh, J.1
-
15
-
-
84887252097
-
Voltage-gated sodium channels as therapeutic targets
-
John Wiley & Sons, Hoboken, NJ, L.M. Botana, M.I. Loza (Eds.)
-
Wingerd J.S., Vetter I., Lewis R.J. Voltage-gated sodium channels as therapeutic targets. Therapeutic Targets. Modulation, Inhibition and Activation 2012, 63-122. John Wiley & Sons, Hoboken, NJ. L.M. Botana, M.I. Loza (Eds.).
-
(2012)
Therapeutic Targets. Modulation, Inhibition and Activation
, pp. 63-122
-
-
Wingerd, J.S.1
Vetter, I.2
Lewis, R.J.3
-
16
-
-
0023691731
-
Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics
-
Bialojan C., Takai A. Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics. Biochem. J. 1988, 256(1):283-290.
-
(1988)
Biochem. J.
, vol.256
, Issue.1
, pp. 283-290
-
-
Bialojan, C.1
Takai, A.2
-
17
-
-
34547121749
-
A structural basis for regulation of actin polymerization by pectenotoxins
-
Allingham J.S., Miles C.O., Rayment I. A structural basis for regulation of actin polymerization by pectenotoxins. J. Mol. Biol. 2007, 371(4):959-970.
-
(2007)
J. Mol. Biol.
, vol.371
, Issue.4
, pp. 959-970
-
-
Allingham, J.S.1
Miles, C.O.2
Rayment, I.3
-
18
-
-
84891593472
-
Surface plasmon resonance biosensor method for palytoxin detection based on na+, k+-ATPase affinity
-
Alfonso A., et al. Surface plasmon resonance biosensor method for palytoxin detection based on na+, k+-ATPase affinity. Toxins (Basel) 2014, 6(1):96-107.
-
(2014)
Toxins (Basel)
, vol.6
, Issue.1
, pp. 96-107
-
-
Alfonso, A.1
-
19
-
-
0034868522
-
Maitotoxin-induced calcium entry in human lymphocytes: modulation by yessotoxin, Ca(2+) channel blockers and kinases
-
de la Rosa L.A., et al. Maitotoxin-induced calcium entry in human lymphocytes: modulation by yessotoxin, Ca(2+) channel blockers and kinases. Cell Signal. 2001, 13(10):711-716.
-
(2001)
Cell Signal.
, vol.13
, Issue.10
, pp. 711-716
-
-
de la Rosa, L.A.1
-
20
-
-
77950547338
-
Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism
-
Bourne Y., et al. Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism. Proc. Natl. Acad. Sci. U.S.A. 2010, 107(13):6076-6081.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, Issue.13
, pp. 6076-6081
-
-
Bourne, Y.1
-
21
-
-
84874075987
-
Development of a solid-phase receptor-based assay for the detection of cyclic imines using a microsphere-flow cytometry system
-
Rodriguez L.P., et al. Development of a solid-phase receptor-based assay for the detection of cyclic imines using a microsphere-flow cytometry system. Anal. Chem. 2013, 85(4):2340-2347.
-
(2013)
Anal. Chem.
, vol.85
, Issue.4
, pp. 2340-2347
-
-
Rodriguez, L.P.1
-
22
-
-
42149138554
-
Domoic acid, the molecular and integrative basis to domoic acid toxicity
-
Blackwell Publishing, Ames, Iowa, L.M. Botana (Ed.)
-
Ramsdell J.S. Domoic acid, the molecular and integrative basis to domoic acid toxicity. Phytotoxins, Chemistry and Biochemistry 2007, 223-250. Blackwell Publishing, Ames, Iowa. L.M. Botana (Ed.).
-
(2007)
Phytotoxins, Chemistry and Biochemistry
, pp. 223-250
-
-
Ramsdell, J.S.1
-
23
-
-
0002893951
-
Winter toxicity of unknown aetiology in mussels
-
MCMahon T., Silke J. Winter toxicity of unknown aetiology in mussels. Harmful Algae 1996, 14:2.
-
(1996)
Harmful Algae
, vol.14
, pp. 2
-
-
McMahon, T.1
Silke, J.2
-
24
-
-
0032582026
-
Azaspiracid, a new marine toxin having unique spiro ring assemblies, isolated from Irish mussels Mytilus edulis
-
Satake M., et al. Azaspiracid, a new marine toxin having unique spiro ring assemblies, isolated from Irish mussels Mytilus edulis. J. Am. Chem. Soc. 1998, 120(38):9967-9968.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, Issue.38
, pp. 9967-9968
-
-
Satake, M.1
-
25
-
-
33644520246
-
Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product
-
Nicolaou K., et al. Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product. J. Am. Chem. Soc. 2006, 128(7):2258-2267.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, Issue.7
, pp. 2258-2267
-
-
Nicolaou, K.1
-
26
-
-
0042035641
-
Total synthesis of the proposed azaspiracid-1 structure, part 2: coupling of the C1-C20, C21-C27, and C28-C40 fragments and completion of the synthesis
-
Nicolaou K.C., et al. Total synthesis of the proposed azaspiracid-1 structure, part 2: coupling of the C1-C20, C21-C27, and C28-C40 fragments and completion of the synthesis. Angew. Chem. Int. Ed. Engl. 2003, 42(31):3649-3653.
-
(2003)
Angew. Chem. Int. Ed. Engl.
, vol.42
, Issue.31
, pp. 3649-3653
-
-
Nicolaou, K.C.1
-
27
-
-
84889413802
-
Structural assignment and total synthesis of azaspiracid-1
-
Blackwell Publishing, Ames, Iowa, L.M. Botana (Ed.)
-
Frederick M.O., et al. Structural assignment and total synthesis of azaspiracid-1. Phytotoxins, Chemistry and Biochemistry 2007, 297-309. Blackwell Publishing, Ames, Iowa. L.M. Botana (Ed.).
-
(2007)
Phytotoxins, Chemistry and Biochemistry
, pp. 297-309
-
-
Frederick, M.O.1
-
28
-
-
0037355392
-
Detection of five new hydroxyl analogues of azaspiracids in shellfish using multiple tandem mass spectrometry
-
James K.J., et al. Detection of five new hydroxyl analogues of azaspiracids in shellfish using multiple tandem mass spectrometry. Toxicon 2003, 41(3):277-283.
-
(2003)
Toxicon
, vol.41
, Issue.3
, pp. 277-283
-
-
James, K.J.1
-
29
-
-
84937161320
-
Azaspiracids: chemistry, biosynthesis, metabolism, and detection
-
CRC Press, Boca Ratón, L.M. Botana (Ed.)
-
Hess P., et al. Azaspiracids: chemistry, biosynthesis, metabolism, and detection. Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection 2014, 799-821. CRC Press, Boca Ratón. L.M. Botana (Ed.).
-
(2014)
Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection
, pp. 799-821
-
-
Hess, P.1
-
30
-
-
0037305986
-
Ubiquitous 'benign' alga emerges as the cause of shellfish contamination responsible for the human toxic syndrome, azaspiracid poisoning
-
James K.J., et al. Ubiquitous 'benign' alga emerges as the cause of shellfish contamination responsible for the human toxic syndrome, azaspiracid poisoning. Toxicon 2003, 41(2):145-151.
-
(2003)
Toxicon
, vol.41
, Issue.2
, pp. 145-151
-
-
James, K.J.1
-
31
-
-
69249153420
-
Azadinium spinosum gen. et sp. nov. (Dinophyceae) identified as a primary producer of azaspiracid toxins
-
Tillmann U., et al. Azadinium spinosum gen. et sp. nov. (Dinophyceae) identified as a primary producer of azaspiracid toxins. Eur. J. Phycol. 2009, 44:63-79.
-
(2009)
Eur. J. Phycol.
, vol.44
, pp. 63-79
-
-
Tillmann, U.1
-
32
-
-
84863488452
-
New azaspiracids in Amphidomataceae (Dinophyceae)
-
Krock B., et al. New azaspiracids in Amphidomataceae (Dinophyceae). Toxicon 2012, 60(5):830-839.
-
(2012)
Toxicon
, vol.60
, Issue.5
, pp. 830-839
-
-
Krock, B.1
-
33
-
-
0141767093
-
The first identification of azaspiracids in shellfish from France and Spain
-
Magdalena A.B., et al. The first identification of azaspiracids in shellfish from France and Spain. Toxicon 2003, 42:105-108.
-
(2003)
Toxicon
, vol.42
, pp. 105-108
-
-
Magdalena, A.B.1
-
34
-
-
38049025830
-
Structural confirmation and occurrence of azaspiracids in Scandinavian brown crabs (Cancer pagurus)
-
Torgersen T., et al. Structural confirmation and occurrence of azaspiracids in Scandinavian brown crabs (Cancer pagurus). Toxicon 2008, 51(1):93-101.
-
(2008)
Toxicon
, vol.51
, Issue.1
, pp. 93-101
-
-
Torgersen, T.1
-
35
-
-
44949084349
-
Confirmation by LC-MS/MS of azaspiracids in shellfish from the Portuguese north-western coast
-
Vale P., Bire R., Hess P. Confirmation by LC-MS/MS of azaspiracids in shellfish from the Portuguese north-western coast. Toxicon 2008, 51(8):1449-1456.
-
(2008)
Toxicon
, vol.51
, Issue.8
, pp. 1449-1456
-
-
Vale, P.1
Bire, R.2
Hess, P.3
-
36
-
-
72749106350
-
First identification of azaspiracid and spirolides in Mesodesma donacium and Mulinia edulis from Northern Chile
-
Alvarez G., et al. First identification of azaspiracid and spirolides in Mesodesma donacium and Mulinia edulis from Northern Chile. Toxicon 2010, 55(2-3):638-641.
-
(2010)
Toxicon
, vol.55
, Issue.2-3
, pp. 638-641
-
-
Alvarez, G.1
-
37
-
-
84858707694
-
First report of the photosynthetic dinoflagellate genus Azadinium in the Pacific Ocean: morphology and molecular characterization of Azadinium cf. poporum
-
Potvin E., et al. First report of the photosynthetic dinoflagellate genus Azadinium in the Pacific Ocean: morphology and molecular characterization of Azadinium cf. poporum. J. Eukaryot. Microbiol. 2012, 59(2):145-156.
-
(2012)
J. Eukaryot. Microbiol.
, vol.59
, Issue.2
, pp. 145-156
-
-
Potvin, E.1
-
38
-
-
84901838547
-
AZA: the producing organisms-biology and trophic transfer
-
CRC Press, Boca Ratón, L.M. Botana (Ed.)
-
Tillmann U., et al. AZA: the producing organisms-biology and trophic transfer. Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection 2014, 773-795. CRC Press, Boca Ratón. L.M. Botana (Ed.).
-
(2014)
Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection
, pp. 773-795
-
-
Tillmann, U.1
-
39
-
-
58149109437
-
Evaluation of various pH and temperature conditions on the stability of azaspiracids and their importance in preparative isolation and toxicological studies
-
Alfonso C., et al. Evaluation of various pH and temperature conditions on the stability of azaspiracids and their importance in preparative isolation and toxicological studies. Anal. Chem. 2008, 80(24):9672-9680.
-
(2008)
Anal. Chem.
, vol.80
, Issue.24
, pp. 9672-9680
-
-
Alfonso, C.1
-
40
-
-
68949089361
-
Opinion of the scientific panel on contaminants in the food chain on a request from the European Commission on marine biotoxins in shellfish-azaspiracids
-
Panel E.C. Opinion of the scientific panel on contaminants in the food chain on a request from the European Commission on marine biotoxins in shellfish-azaspiracids. EFSA J. 2008, 723:1-52.
-
(2008)
EFSA J.
, vol.723
, pp. 1-52
-
-
Panel, E.C.1
-
41
-
-
85135681967
-
Azaspiracids: toxicology, pharmacology and risk assessment
-
CRC Press, Boca Ratón, L.M. Botana (Ed.)
-
Twiner M.J., Hess P., Doucette G.J. Azaspiracids: toxicology, pharmacology and risk assessment. Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection 2014, 824-855. CRC Press, Boca Ratón. L.M. Botana (Ed.).
-
(2014)
Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection
, pp. 824-855
-
-
Twiner, M.J.1
Hess, P.2
Doucette, G.J.3
-
42
-
-
59849117173
-
Formation of Azaspiracids-3, -4, -6, and -9 via decarboxylation of carboxyazaspiracid metabolites from shellfish
-
McCarron P., et al. Formation of Azaspiracids-3, -4, -6, and -9 via decarboxylation of carboxyazaspiracid metabolites from shellfish. J. Agric. Food Chem. 2009, 57(1):160-169.
-
(2009)
J. Agric. Food Chem.
, vol.57
, Issue.1
, pp. 160-169
-
-
McCarron, P.1
-
43
-
-
77958508740
-
Sub-lethal dosing of azaspiracid-1 in female NMRI mice
-
Aasen J.A., et al. Sub-lethal dosing of azaspiracid-1 in female NMRI mice. Toxicon 2010, 56(8):1419-1425.
-
(2010)
Toxicon
, vol.56
, Issue.8
, pp. 1419-1425
-
-
Aasen, J.A.1
-
44
-
-
79955024761
-
Combined oral toxicity of azaspiracid-1 and yessotoxin in female NMRI mice
-
Aasen J.A., et al. Combined oral toxicity of azaspiracid-1 and yessotoxin in female NMRI mice. Toxicon 2011, 57(6):909-917.
-
(2011)
Toxicon
, vol.57
, Issue.6
, pp. 909-917
-
-
Aasen, J.A.1
-
45
-
-
61449087418
-
Mussel-associated azaspiracid intoxication in the United States
-
Klontz K.C., et al. Mussel-associated azaspiracid intoxication in the United States. Ann. Intern. Med. 2009, 150(5):361.
-
(2009)
Ann. Intern. Med.
, vol.150
, Issue.5
, pp. 361
-
-
Klontz, K.C.1
-
46
-
-
0033974774
-
Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland
-
Ito E., et al. Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland. Toxicon 2000, 38:917-930.
-
(2000)
Toxicon
, vol.38
, pp. 917-930
-
-
Ito, E.1
-
47
-
-
0036027438
-
Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels
-
Ito E., et al. Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels. Toxicon 2002, 40(2):193-203.
-
(2002)
Toxicon
, vol.40
, Issue.2
, pp. 193-203
-
-
Ito, E.1
-
49
-
-
84864067373
-
Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route
-
Aune T., et al. Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route. Toxicon 2012, 60(5):895-906.
-
(2012)
Toxicon
, vol.60
, Issue.5
, pp. 895-906
-
-
Aune, T.1
-
50
-
-
0036000286
-
Azaspiracid-1, a potent, nonapoptotic new phycotoxin with several cell targets
-
Roman Y., et al. Azaspiracid-1, a potent, nonapoptotic new phycotoxin with several cell targets. Cell Signal. 2002, 14(8):703-716.
-
(2002)
Cell Signal.
, vol.14
, Issue.8
, pp. 703-716
-
-
Roman, Y.1
-
51
-
-
19344378520
-
Cytotoxic and cytoskeletal effects of azaspiracid-1 on mammalian cell lines
-
Twiner M.J., et al. Cytotoxic and cytoskeletal effects of azaspiracid-1 on mammalian cell lines. Toxicon 2005, 45(7):891-900.
-
(2005)
Toxicon
, vol.45
, Issue.7
, pp. 891-900
-
-
Twiner, M.J.1
-
52
-
-
34250021053
-
Irreversible cytoskeletal disarrangement is independent of caspase activation during in vitro azaspiracid toxicity in human neuroblastoma cells
-
Vilarino N., et al. Irreversible cytoskeletal disarrangement is independent of caspase activation during in vitro azaspiracid toxicity in human neuroblastoma cells. Biochem. Pharmacol. 2007, 74(2):327-335.
-
(2007)
Biochem. Pharmacol.
, vol.74
, Issue.2
, pp. 327-335
-
-
Vilarino, N.1
-
53
-
-
77951528520
-
Involvement of caspase activation in azaspiracid-induced neurotoxicity in neocortical neurons
-
Cao Z., et al. Involvement of caspase activation in azaspiracid-induced neurotoxicity in neocortical neurons. Toxicol. Sci. 2010, 114(2):323-334.
-
(2010)
Toxicol. Sci.
, vol.114
, Issue.2
, pp. 323-334
-
-
Cao, Z.1
-
54
-
-
84863924670
-
Induction of apoptosis pathways in several cell lines following exposure to the marine algal toxin azaspiracid
-
Twiner M.J., et al. Induction of apoptosis pathways in several cell lines following exposure to the marine algal toxin azaspiracid. Chem. Res. Toxicol. 2012, 25(7):1493-1501.
-
(2012)
Chem. Res. Toxicol.
, vol.25
, Issue.7
, pp. 1493-1501
-
-
Twiner, M.J.1
-
55
-
-
35848947250
-
The c-Jun-N-terminal kinase is involved in the neurotoxic effect of azaspiracid-1
-
Vale C., et al. The c-Jun-N-terminal kinase is involved in the neurotoxic effect of azaspiracid-1. Cell Physiol. Biochem. 2007, 20(6):957-966.
-
(2007)
Cell Physiol. Biochem.
, vol.20
, Issue.6
, pp. 957-966
-
-
Vale, C.1
-
56
-
-
57049171334
-
Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: involvement of the c-Jun N-terminal kinase
-
Vale C., et al. Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: involvement of the c-Jun N-terminal kinase. J. Neurosci. Res. 2008, 86(13):2952-2962.
-
(2008)
J. Neurosci. Res.
, vol.86
, Issue.13
, pp. 2952-2962
-
-
Vale, C.1
-
57
-
-
0035830903
-
Cleavage of focal adhesion kinase by different proteases during SRC-regulated transformation and apoptosis. Distinct roles for calpain and caspases
-
Carragher N.O., et al. Cleavage of focal adhesion kinase by different proteases during SRC-regulated transformation and apoptosis. Distinct roles for calpain and caspases. J. Biol. Chem. 2001, 276(6):4270-4275.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.6
, pp. 4270-4275
-
-
Carragher, N.O.1
-
58
-
-
53549095708
-
Azaspiracid substituent at C1 is relevant to in vitro toxicity
-
Vilarino N., et al. Azaspiracid substituent at C1 is relevant to in vitro toxicity. Chem. Res. Toxicol. 2008, 21(9):1823-1831.
-
(2008)
Chem. Res. Toxicol.
, vol.21
, Issue.9
, pp. 1823-1831
-
-
Vilarino, N.1
-
59
-
-
33745222056
-
Azaspiracids modulate intracellular pH levels in human lymphocytes
-
Alfonso A., et al. Azaspiracids modulate intracellular pH levels in human lymphocytes. Biochem. Biophys. Res. Commun. 2006, 346(3):1091-1099.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.346
, Issue.3
, pp. 1091-1099
-
-
Alfonso, A.1
-
60
-
-
19444373932
-
Azaspiracid-4 inhibits Ca2+ entry by stored operated channels in human T lymphocytes
-
Alfonso A., et al. Azaspiracid-4 inhibits Ca2+ entry by stored operated channels in human T lymphocytes. Biochem. Pharmacol. 2005, 69(11):1627-1636.
-
(2005)
Biochem. Pharmacol.
, vol.69
, Issue.11
, pp. 1627-1636
-
-
Alfonso, A.1
-
61
-
-
6344278381
-
Effects of Azaspiracids 2 and 3 on intracellular cAMP, [Ca2+], and pH
-
Roman Y., et al. Effects of Azaspiracids 2 and 3 on intracellular cAMP, [Ca2+], and pH. Chem. Res. Toxicol. 2004, 17(10):1338-1349.
-
(2004)
Chem. Res. Toxicol.
, vol.17
, Issue.10
, pp. 1338-1349
-
-
Roman, Y.1
-
62
-
-
77955841471
-
The marine polyether gambierol enhances muscle contraction and blocks a transient K(+) current in skeletal muscle cells
-
Schlumberger S., et al. The marine polyether gambierol enhances muscle contraction and blocks a transient K(+) current in skeletal muscle cells. Toxicon 2010, 56(5):785-791.
-
(2010)
Toxicon
, vol.56
, Issue.5
, pp. 785-791
-
-
Schlumberger, S.1
-
63
-
-
77955844292
-
Dual action of a dinoflagellate-derived precursor of Pacific ciguatoxins (P-CTX-4B) on voltage-dependent K(+) and Na(+) channels of single myelinated axons
-
Schlumberger S., et al. Dual action of a dinoflagellate-derived precursor of Pacific ciguatoxins (P-CTX-4B) on voltage-dependent K(+) and Na(+) channels of single myelinated axons. Toxicon 2010, 56:768-775.
-
(2010)
Toxicon
, vol.56
, pp. 768-775
-
-
Schlumberger, S.1
-
64
-
-
0033558371
-
Neurotoxins targeting receptor site 5 of voltage-dependent sodium channels increase the nodal volume of myelinated axons
-
Mattei C., et al. Neurotoxins targeting receptor site 5 of voltage-dependent sodium channels increase the nodal volume of myelinated axons. J. Neurosci. Res. 1999, 55(6):666-673.
-
(1999)
J. Neurosci. Res.
, vol.55
, Issue.6
, pp. 666-673
-
-
Mattei, C.1
-
65
-
-
0030004259
-
Reversed mode Na(+)-Ca2+ exchange activated by ciguatoxin (CTX-1b) enhances acetylcholine release from Torpedo cholinergic synaptosomes
-
Gaudry-Talarmain Y.M., et al. Reversed mode Na(+)-Ca2+ exchange activated by ciguatoxin (CTX-1b) enhances acetylcholine release from Torpedo cholinergic synaptosomes. Ann. N.Y. Acad. Sci. 1996, 779:404-406.
-
(1996)
Ann. N.Y. Acad. Sci.
, vol.779
, pp. 404-406
-
-
Gaudry-Talarmain, Y.M.1
-
66
-
-
0027023486
-
Ciguatoxin-induced changes in acetylcholine release and in cytosolic calcium levels
-
Molgo J., et al. Ciguatoxin-induced changes in acetylcholine release and in cytosolic calcium levels. Bull. Soc. Pathol. Exot. 1992, 85(5 Pt 2):486-488.
-
(1992)
Bull. Soc. Pathol. Exot.
, vol.85
, Issue.5
, pp. 486-488
-
-
Molgo, J.1
-
67
-
-
33846404512
-
Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study
-
Vale C., et al. Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study. J. Med. Chem. 2007, 50(2):356-363.
-
(2007)
J. Med. Chem.
, vol.50
, Issue.2
, pp. 356-363
-
-
Vale, C.1
-
68
-
-
77952058708
-
Calcium oscillations induced by gambierol in cerebellar granule cells
-
Alonso E., et al. Calcium oscillations induced by gambierol in cerebellar granule cells. J. Cell. Biochem. 2010, 110(2):497-508.
-
(2010)
J. Cell. Biochem.
, vol.110
, Issue.2
, pp. 497-508
-
-
Alonso, E.1
-
69
-
-
56849120307
-
Marine toxins and the cytoskeleton: azaspiracids
-
Vilarino N. Marine toxins and the cytoskeleton: azaspiracids. FEBS J. 2008, 275(24):6075-6081.
-
(2008)
FEBS J.
, vol.275
, Issue.24
, pp. 6075-6081
-
-
Vilarino, N.1
-
70
-
-
33845266744
-
Cell growth inhibition and actin cytoskeleton disorganization induced by azaspiracid-1 structure-activity studies
-
Vilarino N., et al. Cell growth inhibition and actin cytoskeleton disorganization induced by azaspiracid-1 structure-activity studies. Chem. Res. Toxicol. 2006, 19(11):1459-1466.
-
(2006)
Chem. Res. Toxicol.
, vol.19
, Issue.11
, pp. 1459-1466
-
-
Vilarino, N.1
-
71
-
-
33846512435
-
Azaspiracid-1 alters the E-cadherin pool in epithelial cells
-
Ronzitti G., et al. Azaspiracid-1 alters the E-cadherin pool in epithelial cells. Toxicol. Sci. 2007, 95(2):427-435.
-
(2007)
Toxicol. Sci.
, vol.95
, Issue.2
, pp. 427-435
-
-
Ronzitti, G.1
-
72
-
-
39149132818
-
Transcriptional profiling and inhibition of cholesterol biosynthesis in human T lymphocyte cells by the marine toxin azaspiracid
-
Twiner M., et al. Transcriptional profiling and inhibition of cholesterol biosynthesis in human T lymphocyte cells by the marine toxin azaspiracid. Genomics 2008, 91:289-300.
-
(2008)
Genomics
, vol.91
, pp. 289-300
-
-
Twiner, M.1
-
73
-
-
75249087776
-
Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons
-
Vale C., et al. Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons. Toxicol. Sci. 2010, 113(1):158-168.
-
(2010)
Toxicol. Sci.
, vol.113
, Issue.1
, pp. 158-168
-
-
Vale, C.1
-
74
-
-
63649141239
-
Proteomic response of human neuroblastoma cells to azaspiracid-1
-
Kellmann R., et al. Proteomic response of human neuroblastoma cells to azaspiracid-1. J. Proteomics 2009, 72(4):695-707.
-
(2009)
J. Proteomics
, vol.72
, Issue.4
, pp. 695-707
-
-
Kellmann, R.1
-
75
-
-
77955874348
-
Azaspiracid-1 inhibits endocytosis of plasma membrane proteins in epithelial cells
-
Bellocci M., et al. Azaspiracid-1 inhibits endocytosis of plasma membrane proteins in epithelial cells. Toxicol. Sci. 2010, 117(1):109-121.
-
(2010)
Toxicol. Sci.
, vol.117
, Issue.1
, pp. 109-121
-
-
Bellocci, M.1
-
76
-
-
84875176985
-
Azaspiracid-1 inhibits the maturation of cathepsin D in mammalian cells
-
Sala G.L., et al. Azaspiracid-1 inhibits the maturation of cathepsin D in mammalian cells. Chem. Res. Toxicol. 2013, 26(3):444-455.
-
(2013)
Chem. Res. Toxicol.
, vol.26
, Issue.3
, pp. 444-455
-
-
Sala, G.L.1
-
77
-
-
84866402236
-
Marine algal toxin azaspiracid is an open-state blocker of hERG potassium channels
-
Twiner M.J., et al. Marine algal toxin azaspiracid is an open-state blocker of hERG potassium channels. Chem. Res. Toxicol. 2012, 25(9):1975-1984.
-
(2012)
Chem. Res. Toxicol.
, vol.25
, Issue.9
, pp. 1975-1984
-
-
Twiner, M.J.1
-
78
-
-
84893933186
-
In vivo arrhythmogenicity of the marine biotoxin azaspiracid-2 in rats
-
Ferreiro S.F., et al. In vivo arrhythmogenicity of the marine biotoxin azaspiracid-2 in rats. Arch. Toxicol. 2014, 88(2):425-434.
-
(2014)
Arch. Toxicol.
, vol.88
, Issue.2
, pp. 425-434
-
-
Ferreiro, S.F.1
-
79
-
-
0030831632
-
Identification of Protoceratium reticulatum as the biogenetic organ of yessotoxin
-
Satake M., MacKenzie L., Yasumoto T. Identification of Protoceratium reticulatum as the biogenetic organ of yessotoxin. Nat. Toxins 1997, 5(4):164-167.
-
(1997)
Nat. Toxins
, vol.5
, Issue.4
, pp. 164-167
-
-
Satake, M.1
MacKenzie, L.2
Yasumoto, T.3
-
80
-
-
9744246051
-
Polyhydroxylated amide analogs of yessotoxin from Protoceratium reticulatum
-
Miles C.O., et al. Polyhydroxylated amide analogs of yessotoxin from Protoceratium reticulatum. Toxicon 2005, 45(1):61-71.
-
(2005)
Toxicon
, vol.45
, Issue.1
, pp. 61-71
-
-
Miles, C.O.1
-
81
-
-
0001695256
-
Isolation and structure of Yessotoxin, a novel polyether compound implicated in diarrhetic shellfish poisoning
-
Murata M., et al. Isolation and structure of Yessotoxin, a novel polyether compound implicated in diarrhetic shellfish poisoning. Tetrahedron Lett. 1987, 28:5869-5872.
-
(1987)
Tetrahedron Lett.
, vol.28
, pp. 5869-5872
-
-
Murata, M.1
-
82
-
-
0030799171
-
Two new analogs of yessotoxin, homoyessotoxin and 45-hydroxyhomoyessotoxin, isolated from mussels of the Adriatic Sea
-
Satake M., et al. Two new analogs of yessotoxin, homoyessotoxin and 45-hydroxyhomoyessotoxin, isolated from mussels of the Adriatic Sea. Nat. Toxins 1997, 5(3):107-110.
-
(1997)
Nat. Toxins
, vol.5
, Issue.3
, pp. 107-110
-
-
Satake, M.1
-
83
-
-
0031081771
-
Yessotoxin in mussels of the northern Adriatic Sea
-
Ciminiello P., et al. Yessotoxin in mussels of the northern Adriatic Sea. Toxicon 1997, 35(2):177-183.
-
(1997)
Toxicon
, vol.35
, Issue.2
, pp. 177-183
-
-
Ciminiello, P.1
-
84
-
-
85007926887
-
Diarrhetic shellfish toxins in Nowegian mussels
-
Lee J., et al. Diarrhetic shellfish toxins in Nowegian mussels. Nippon Suisan Gakkaishi 1988, 54:1953-1957.
-
(1988)
Nippon Suisan Gakkaishi
, vol.54
, pp. 1953-1957
-
-
Lee, J.1
-
85
-
-
0032569872
-
Isolation of adriatoxin, a new analogue of yessotoxin from mussels of the Adriatic sea
-
Ciminiello P., et al. Isolation of adriatoxin, a new analogue of yessotoxin from mussels of the Adriatic sea. Tetrahedron Lett. 1998, 39(48):8897-8900.
-
(1998)
Tetrahedron Lett.
, vol.39
, Issue.48
, pp. 8897-8900
-
-
Ciminiello, P.1
-
86
-
-
0032928793
-
High levels of yessotoxin in mussels and presence of yessotoxin and homoyessotoxin in dinoflagellates of the Adriatic Sea
-
Draisci R., et al. High levels of yessotoxin in mussels and presence of yessotoxin and homoyessotoxin in dinoflagellates of the Adriatic Sea. Toxicon 1999, 37(8):1187-1193.
-
(1999)
Toxicon
, vol.37
, Issue.8
, pp. 1187-1193
-
-
Draisci, R.1
-
87
-
-
84856245690
-
Toxin levels and profiles in microalgae from the north-Western Adriatic Sea-15 years of studies on cultured species
-
Pistocchi R., et al. Toxin levels and profiles in microalgae from the north-Western Adriatic Sea-15 years of studies on cultured species. Mar. Drugs 2012, 10(1):140-162.
-
(2012)
Mar. Drugs
, vol.10
, Issue.1
, pp. 140-162
-
-
Pistocchi, R.1
-
88
-
-
22044454000
-
Isolation and identification of (44-R, S)-44,55-dihydroxyyessotoxin from Protoceratium reticulatum, and its occurrence in extracts of shellfish from New Zealand, Norway and Canada
-
Finch S.C., et al. Isolation and identification of (44-R, S)-44,55-dihydroxyyessotoxin from Protoceratium reticulatum, and its occurrence in extracts of shellfish from New Zealand, Norway and Canada. Toxicon 2005, 46(2):160-170.
-
(2005)
Toxicon
, vol.46
, Issue.2
, pp. 160-170
-
-
Finch, S.C.1
-
89
-
-
8844262483
-
Isolation of 41a-homoyessotoxin and the identification of 9-methyl-41a-homoyessotoxin and nor-ring A-yessotoxin from Protoceratium reticulatum
-
Miles C.O., et al. Isolation of 41a-homoyessotoxin and the identification of 9-methyl-41a-homoyessotoxin and nor-ring A-yessotoxin from Protoceratium reticulatum. Chem. Res. Toxicol. 2004, 17(11):1414-1422.
-
(2004)
Chem. Res. Toxicol.
, vol.17
, Issue.11
, pp. 1414-1422
-
-
Miles, C.O.1
-
90
-
-
3042615951
-
Isolation of a 1,3-enone isomer of heptanor-41-oxoyessotoxin from Protoceratium reticulatum cultures
-
Miles C.O., et al. Isolation of a 1,3-enone isomer of heptanor-41-oxoyessotoxin from Protoceratium reticulatum cultures. Toxicon 2004, 44(3):325-336.
-
(2004)
Toxicon
, vol.44
, Issue.3
, pp. 325-336
-
-
Miles, C.O.1
-
91
-
-
85056317583
-
Toxicology of the Yessotoxins
-
CRC Press (Taylor and Francis Group), Boca Raton, FL, L.M. Botana (Ed.)
-
Munday R., Aune T., Rossini G.P. Toxicology of the Yessotoxins. Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection 2008, 329-339. CRC Press (Taylor and Francis Group), Boca Raton, FL. L.M. Botana (Ed.).
-
(2008)
Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection
, pp. 329-339
-
-
Munday, R.1
Aune, T.2
Rossini, G.P.3
-
92
-
-
68949089361
-
Scientific opinion on marine biotoxins in shellfish-Yessotoxin group. EFSA Panel on Contaminants in the Food Chain (CONTAM)
-
Panel E.C. Scientific opinion on marine biotoxins in shellfish-Yessotoxin group. EFSA Panel on Contaminants in the Food Chain (CONTAM). EFSA J. 2008, 907:1-62.
-
(2008)
EFSA J.
, vol.907
, pp. 1-62
-
-
Panel, E.C.1
-
93
-
-
0036028014
-
Comparison of oral and intraperitoneal toxicity of yessotoxin towards mice
-
Aune T., et al. Comparison of oral and intraperitoneal toxicity of yessotoxin towards mice. Toxicon 2002, 40(1):77-82.
-
(2002)
Toxicon
, vol.40
, Issue.1
, pp. 77-82
-
-
Aune, T.1
-
94
-
-
1642421706
-
Short-term oral toxicity of homoyessotoxins, yessotoxin and okadaic acid in mice
-
Tubaro A., et al. Short-term oral toxicity of homoyessotoxins, yessotoxin and okadaic acid in mice. Toxicon 2004, 43(4):439-445.
-
(2004)
Toxicon
, vol.43
, Issue.4
, pp. 439-445
-
-
Tubaro, A.1
-
95
-
-
0038019996
-
Oral and intraperitoneal acute toxicity studies of yessotoxin and homoyessotoxins in mice
-
Tubaro A., et al. Oral and intraperitoneal acute toxicity studies of yessotoxin and homoyessotoxins in mice. Toxicon 2003, 41(7):783-792.
-
(2003)
Toxicon
, vol.41
, Issue.7
, pp. 783-792
-
-
Tubaro, A.1
-
96
-
-
84866430594
-
Chemistry, origins and distribution of yessotoxin and its analogues
-
Blackwell Publishing, Ames, Iowa, L.M. Botana (Ed.)
-
Hess P., Aasen J. Chemistry, origins and distribution of yessotoxin and its analogues. Phytotoxins, Chemistry and Biochemistry 2007, 187-202. Blackwell Publishing, Ames, Iowa. L.M. Botana (Ed.).
-
(2007)
Phytotoxins, Chemistry and Biochemistry
, pp. 187-202
-
-
Hess, P.1
Aasen, J.2
-
97
-
-
84945191822
-
COMMISSION REGULATION (EU) No 786/2013 of 16 August 2013 amending Annex III to Regulation (EC) No 853/2004 of the European Parliament and of the Council as regards the permitted limits of yessotoxins in live bivalve molluscs
-
Commission regulation
-
COMMISSION REGULATION (EU) No 786/2013 of 16 August 2013 amending Annex III to Regulation (EC) No 853/2004 of the European Parliament and of the Council as regards the permitted limits of yessotoxins in live bivalve molluscs. Official Journal of the European Communities 2013, L220:14. Commission regulation.
-
(2013)
Official Journal of the European Communities
, vol.L220
, pp. 14
-
-
-
99
-
-
51049100398
-
Effect of mouse strain and gender on LD(50) of yessotoxin
-
Aune T., et al. Effect of mouse strain and gender on LD(50) of yessotoxin. Toxicon 2008, 52(4):535-540.
-
(2008)
Toxicon
, vol.52
, Issue.4
, pp. 535-540
-
-
Aune, T.1
-
100
-
-
0025011201
-
Histopathological studies on experimental marine toxin poisoning-5. The effects in mice of yessotoxin isolated from Patinopecten yessoensis and of a desulfated derivative
-
Terao K., et al. Histopathological studies on experimental marine toxin poisoning-5. The effects in mice of yessotoxin isolated from Patinopecten yessoensis and of a desulfated derivative. Toxicon 1990, 28:1095-1104.
-
(1990)
Toxicon
, vol.28
, pp. 1095-1104
-
-
Terao, K.1
-
101
-
-
77953285571
-
Yessotoxins: a toxicological overview
-
Tubaro A., et al. Yessotoxins: a toxicological overview. Toxicon 2010, 56(2):163-172.
-
(2010)
Toxicon
, vol.56
, Issue.2
, pp. 163-172
-
-
Tubaro, A.1
-
103
-
-
43849092325
-
Ultrastructural damage to heart tissue from repeated oral exposure to yessotoxin resolves in 3 months
-
Tubaro A., et al. Ultrastructural damage to heart tissue from repeated oral exposure to yessotoxin resolves in 3 months. Toxicon 2008, 51(7):1225-1235.
-
(2008)
Toxicon
, vol.51
, Issue.7
, pp. 1225-1235
-
-
Tubaro, A.1
-
104
-
-
84884927088
-
Repeated oral co-exposure to yessotoxin and okadaic acid: a short term toxicity study in mice
-
Sosa S., et al. Repeated oral co-exposure to yessotoxin and okadaic acid: a short term toxicity study in mice. Toxicon 2013, 76:94-102.
-
(2013)
Toxicon
, vol.76
, pp. 94-102
-
-
Sosa, S.1
-
106
-
-
0036151289
-
Characterization of distinct apoptotic changes induced by okadaic acid and yessotoxin in the BE(2)-M17 neuroblastoma cell line
-
Leira F., et al. Characterization of distinct apoptotic changes induced by okadaic acid and yessotoxin in the BE(2)-M17 neuroblastoma cell line. Toxicol. In Vitro 2002, 16(1):23-31.
-
(2002)
Toxicol. In Vitro
, vol.16
, Issue.1
, pp. 23-31
-
-
Leira, F.1
-
107
-
-
0036690406
-
Caspase activation and death induced by yessotoxin in HeLa cells
-
Malaguti C., et al. Caspase activation and death induced by yessotoxin in HeLa cells. Toxicol. In Vitro 2002, 16(4):357-363.
-
(2002)
Toxicol. In Vitro
, vol.16
, Issue.4
, pp. 357-363
-
-
Malaguti, C.1
-
108
-
-
33144483540
-
Potent neurotoxic action of the shellfish biotoxin yessotoxin on cultured cerebellar neurons
-
Perez-Gomez A., et al. Potent neurotoxic action of the shellfish biotoxin yessotoxin on cultured cerebellar neurons. Toxicol. Sci. 2006, 90(1):168-177.
-
(2006)
Toxicol. Sci.
, vol.90
, Issue.1
, pp. 168-177
-
-
Perez-Gomez, A.1
-
109
-
-
33749859921
-
Induction of apoptosis by YTX in myoblast cell lines via mitochondrial signalling transduction pathway
-
Korsnes M.S., et al. Induction of apoptosis by YTX in myoblast cell lines via mitochondrial signalling transduction pathway. Toxicol. In Vitro 2006, 20(8):1419-1426.
-
(2006)
Toxicol. In Vitro
, vol.20
, Issue.8
, pp. 1419-1426
-
-
Korsnes, M.S.1
-
110
-
-
33746002005
-
Apoptotic events induced by yessotoxin in myoblast cell lines from rat and mouse
-
Korsnes M.S., et al. Apoptotic events induced by yessotoxin in myoblast cell lines from rat and mouse. Toxicol. In Vitro 2006, 20(7):1077-1087.
-
(2006)
Toxicol. In Vitro
, vol.20
, Issue.7
, pp. 1077-1087
-
-
Korsnes, M.S.1
-
111
-
-
33845196954
-
Cleavage of tensin during cytoskeleton disruption in YTX-induced apoptosis
-
Korsnes M.S., et al. Cleavage of tensin during cytoskeleton disruption in YTX-induced apoptosis. Toxicol. In Vitro 2007, 21(1):9-15.
-
(2007)
Toxicol. In Vitro
, vol.21
, Issue.1
, pp. 9-15
-
-
Korsnes, M.S.1
-
112
-
-
33749643860
-
Lysosomes as the target of yessotoxin in invertebrate and vertebrate cell lines
-
Malagoli D., Marchesini E., Ottaviani E. Lysosomes as the target of yessotoxin in invertebrate and vertebrate cell lines. Toxicol. Lett. 2006, 167(1):75-83.
-
(2006)
Toxicol. Lett.
, vol.167
, Issue.1
, pp. 75-83
-
-
Malagoli, D.1
Marchesini, E.2
Ottaviani, E.3
-
113
-
-
38749087936
-
Yessotoxin inhibits the complete degradation of E-cadherin
-
Callegari F., Rossini G.P. Yessotoxin inhibits the complete degradation of E-cadherin. Toxicology 2008, 244(2-3):133-144.
-
(2008)
Toxicology
, vol.244
, Issue.2-3
, pp. 133-144
-
-
Callegari, F.1
Rossini, G.P.2
-
114
-
-
38749153921
-
Yessotoxin induces the accumulation of altered E-cadherin dimers that are not part of adhesive structures in intact cells
-
Ronzitti G., Rossini G.P. Yessotoxin induces the accumulation of altered E-cadherin dimers that are not part of adhesive structures in intact cells. Toxicology 2008, 244(2-3):145-156.
-
(2008)
Toxicology
, vol.244
, Issue.2-3
, pp. 145-156
-
-
Ronzitti, G.1
Rossini, G.P.2
-
115
-
-
66249137151
-
The algal metabolite yessotoxin affects heterogeneous nuclear ribonucleoproteins in HepG2 cells
-
Young C., et al. The algal metabolite yessotoxin affects heterogeneous nuclear ribonucleoproteins in HepG2 cells. Proteomics 2009, 9:2529-2542.
-
(2009)
Proteomics
, vol.9
, pp. 2529-2542
-
-
Young, C.1
-
116
-
-
79953795499
-
Characterization of apoptotic changes induced by yessotoxin in the Bel7402 human hepatoma cell line
-
Pang M., et al. Characterization of apoptotic changes induced by yessotoxin in the Bel7402 human hepatoma cell line. Mol. Med. Rep. 2011, 4(3):547-552.
-
(2011)
Mol. Med. Rep.
, vol.4
, Issue.3
, pp. 547-552
-
-
Pang, M.1
-
117
-
-
84855236946
-
Yessotoxin induces apoptosis in HL7702 human liver cells
-
Pang M., et al. Yessotoxin induces apoptosis in HL7702 human liver cells. Mol. Med. Rep. 2012, 5(1):211-216.
-
(2012)
Mol. Med. Rep.
, vol.5
, Issue.1
, pp. 211-216
-
-
Pang, M.1
-
118
-
-
29044446498
-
Actin cytoskeleton of rabbit intestinal cells is a target for potent marine phycotoxins
-
Ares I.R., et al. Actin cytoskeleton of rabbit intestinal cells is a target for potent marine phycotoxins. J. Exp. Biol. 2005, 208(Pt 22):4345-4354.
-
(2005)
J. Exp. Biol.
, vol.208
, pp. 4345-4354
-
-
Ares, I.R.1
-
119
-
-
84907559769
-
Therapeutic use of yessotoxins as growth inhibitors of human tumoral cells
-
Patent, U.o.S.d. Compostela, Editor 2004.
-
L.M. Botana et al., Therapeutic use of yessotoxins as growth inhibitors of human tumoral cells, in Patent, U.o.S.d. Compostela, Editor 2004.
-
-
-
Botana, L.M.1
-
120
-
-
84907559768
-
Use of yessotoxin and its derivatives for the treatment of gliomas
-
Patent, U.o.S.d. Compostela, Editor 2012, Spain.
-
J.A. Rubiolo, L.M. Botana, H. López, Use of yessotoxin and its derivatives for the treatment of gliomas, in Patent, U.o.S.d. Compostela, Editor 2012, Spain.
-
-
-
Rubiolo, J.A.1
Botana, L.M.2
López, H.3
-
121
-
-
84864372423
-
Yessotoxin as a tool to study induction of multiple cell death pathways
-
Korsnes M.S. Yessotoxin as a tool to study induction of multiple cell death pathways. Toxins (Basel) 2012, 4(7):568-579.
-
(2012)
Toxins (Basel)
, vol.4
, Issue.7
, pp. 568-579
-
-
Korsnes, M.S.1
-
122
-
-
82655162060
-
Paraptosis-like cell death induced by yessotoxin
-
Korsnes M.S., et al. Paraptosis-like cell death induced by yessotoxin. Toxicol. In Vitro 2011, 25:1764-1770.
-
(2011)
Toxicol. In Vitro
, vol.25
, pp. 1764-1770
-
-
Korsnes, M.S.1
-
123
-
-
0034687754
-
An alternative, nonapoptotic form of programmed cell death
-
Sperandio S., de Belle I., Bredesen D.E. An alternative, nonapoptotic form of programmed cell death. Proc. Natl. Acad. Sci. U.S.A. 2000, 97(26):14376-14381.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, Issue.26
, pp. 14376-14381
-
-
Sperandio, S.1
de Belle, I.2
Bredesen, D.E.3
-
124
-
-
0035313618
-
Modulation of cytosolic calcium levels of human lymphocytes by yessotoxin, a novel marine phycotoxin
-
de la Rosa L.A., et al. Modulation of cytosolic calcium levels of human lymphocytes by yessotoxin, a novel marine phycotoxin. Biochem. Pharmacol. 2001, 61(7):827-833.
-
(2001)
Biochem. Pharmacol.
, vol.61
, Issue.7
, pp. 827-833
-
-
de la Rosa, L.A.1
-
125
-
-
84867535402
-
Role of yessotoxin in calcium and cAMP-crosstalks in primary and K-562 human lymphocytes: the effect is mediated by Anchor kinase a mitochondrial proteins
-
Tobio A., et al. Role of yessotoxin in calcium and cAMP-crosstalks in primary and K-562 human lymphocytes: the effect is mediated by Anchor kinase a mitochondrial proteins. J. Cell. Biochem. 2012, 113(12):3752-3761.
-
(2012)
J. Cell. Biochem.
, vol.113
, Issue.12
, pp. 3752-3761
-
-
Tobio, A.1
-
126
-
-
0037437764
-
Yessotoxin, a novel phycotoxin, activates phosphodiesterase activity. Effect of yessotoxin on cAMP levels in human lymphocytes
-
Alfonso A., et al. Yessotoxin, a novel phycotoxin, activates phosphodiesterase activity. Effect of yessotoxin on cAMP levels in human lymphocytes. Biochem. Pharmacol. 2003, 65(2):193-208.
-
(2003)
Biochem. Pharmacol.
, vol.65
, Issue.2
, pp. 193-208
-
-
Alfonso, A.1
-
127
-
-
84907559767
-
Recent advances in marine phycotoxin mechanisms of action
-
Editions de la SFET-SFET Editions, Paris
-
Alfonso A., et al. Recent advances in marine phycotoxin mechanisms of action. Toxines et Signalisation-Toxins and Signalling 2009, Editions de la SFET-SFET Editions, Paris.
-
(2009)
Toxines et Signalisation-Toxins and Signalling
-
-
Alfonso, A.1
-
128
-
-
33745344183
-
Study of the interaction between different phosphodiesterases and yessotoxin using a resonant mirror biosensor
-
Pazos M.J., et al. Study of the interaction between different phosphodiesterases and yessotoxin using a resonant mirror biosensor. Chem. Res. Toxicol. 2006, 19(6):794-800.
-
(2006)
Chem. Res. Toxicol.
, vol.19
, Issue.6
, pp. 794-800
-
-
Pazos, M.J.1
-
129
-
-
22544481732
-
Kinetic analysis of the interaction between yessotoxin and analogues and immobilized phosphodiesterases using a resonant mirror optical biosensor
-
Pazos M.J., et al. Kinetic analysis of the interaction between yessotoxin and analogues and immobilized phosphodiesterases using a resonant mirror optical biosensor. Chem. Res. Toxicol. 2005, 18(7):1155-1160.
-
(2005)
Chem. Res. Toxicol.
, vol.18
, Issue.7
, pp. 1155-1160
-
-
Pazos, M.J.1
-
130
-
-
56649100789
-
In vitro effects of yessotoxin on a primary culture of rat cardiomyocytes
-
Dell'Ovo V., et al. In vitro effects of yessotoxin on a primary culture of rat cardiomyocytes. Toxicol. Sci. 2008, 106(2):392-399.
-
(2008)
Toxicol. Sci.
, vol.106
, Issue.2
, pp. 392-399
-
-
Dell'Ovo, V.1
-
131
-
-
0034014505
-
Functional compartments in rat mast cells for cAMP and calcium on histamine release
-
Alfonso A., et al. Functional compartments in rat mast cells for cAMP and calcium on histamine release. Cell Signal. 2000, 12(5):343-350.
-
(2000)
Cell Signal.
, vol.12
, Issue.5
, pp. 343-350
-
-
Alfonso, A.1
-
132
-
-
33847068206
-
Overview of PDEs and their regulation
-
Omori K., Kotera J. Overview of PDEs and their regulation. Circ. Res. 2007, 100(3):309-327.
-
(2007)
Circ. Res.
, vol.100
, Issue.3
, pp. 309-327
-
-
Omori, K.1
Kotera, J.2
-
133
-
-
84901754036
-
Role of AKAP 149-PKA-PDE4A complex in cell survival and cell differentiation processes
-
Fernández-Araujo A., et al. Role of AKAP 149-PKA-PDE4A complex in cell survival and cell differentiation processes. Int. J. Biochem. Cell. Biol. 2014, 53:89-101.
-
(2014)
Int. J. Biochem. Cell. Biol.
, vol.53
, pp. 89-101
-
-
Fernández-Araujo, A.1
-
134
-
-
0034740686
-
Regulation of anchoring of the RIIalpha regulatory subunit of PKA to AKAP95 by threonine phosphorylation of RIIalpha: implications for chromosome dynamics at mitosis
-
Landsverk H.B., et al. Regulation of anchoring of the RIIalpha regulatory subunit of PKA to AKAP95 by threonine phosphorylation of RIIalpha: implications for chromosome dynamics at mitosis. J. Cell Sci. 2001, 114(Pt 18):3255-3264.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 3255-3264
-
-
Landsverk, H.B.1
-
135
-
-
0035972254
-
Mistargeting of B-type lamins at the end of mitosis: implications on cell survival and regulation of lamins A/C expression
-
Steen R.L., Collas P. Mistargeting of B-type lamins at the end of mitosis: implications on cell survival and regulation of lamins A/C expression. J. Cell Biol. 2001, 153(3):621-626.
-
(2001)
J. Cell Biol.
, vol.153
, Issue.3
, pp. 621-626
-
-
Steen, R.L.1
Collas, P.2
-
136
-
-
84880352492
-
Translocation of PKC by yessotoxin in an in vitro model of Alzheimer's disease with improvement of tau and beta-amyloid pathology
-
Alonso E., et al. Translocation of PKC by yessotoxin in an in vitro model of Alzheimer's disease with improvement of tau and beta-amyloid pathology. ACS Chem. Neurosci. 2013, 4(7):1062-1070.
-
(2013)
ACS Chem. Neurosci.
, vol.4
, Issue.7
, pp. 1062-1070
-
-
Alonso, E.1
-
137
-
-
84884232840
-
Protein kinase C modulates Aurora-kinase inhibition induced by CCT129202 in HMC-1(560), (816) cell lines
-
Tobio A., et al. Protein kinase C modulates Aurora-kinase inhibition induced by CCT129202 in HMC-1(560), (816) cell lines. Antiinflamm. Antiallergy Agents Med. Chem. 2013, 12(3):265-276.
-
(2013)
Antiinflamm. Antiallergy Agents Med. Chem.
, vol.12
, Issue.3
, pp. 265-276
-
-
Tobio, A.1
-
138
-
-
84890861050
-
Yessotoxin induces ER-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3
-
Rubiolo J.A., et al. Yessotoxin induces ER-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3. Cell Signal. 2014, 26(2):419-432.
-
(2014)
Cell Signal.
, vol.26
, Issue.2
, pp. 419-432
-
-
Rubiolo, J.A.1
-
139
-
-
33847754341
-
Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model
-
Chang C.P., et al. Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model. Hepatology 2007, 45(2):286-296.
-
(2007)
Hepatology
, vol.45
, Issue.2
, pp. 286-296
-
-
Chang, C.P.1
-
140
-
-
37248999267
-
Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb
-
Li Y., et al. Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb. J. Biol. Chem. 2007, 282(49):35803-35813.
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.49
, pp. 35803-35813
-
-
Li, Y.1
-
141
-
-
0033634641
-
Perk is essential for translational regulation and cell survival during the unfolded protein response
-
Harding H.P., et al. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol. Cell 2000, 5(5):897-904.
-
(2000)
Mol. Cell
, vol.5
, Issue.5
, pp. 897-904
-
-
Harding, H.P.1
-
142
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
Harding H.P., et al. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell 2000, 6(5):1099-1108.
-
(2000)
Mol. Cell
, vol.6
, Issue.5
, pp. 1099-1108
-
-
Harding, H.P.1
-
143
-
-
84864797936
-
Cytotoxicity of yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4
-
Martin-Lopez A., et al. Cytotoxicity of yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4. Toxicon 2012, 60(6):1049-1056.
-
(2012)
Toxicon
, vol.60
, Issue.6
, pp. 1049-1056
-
-
Martin-Lopez, A.1
-
144
-
-
80053368054
-
Immunoregulatory potential of marine algal toxins yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4
-
Lopez A.M., et al. Immunoregulatory potential of marine algal toxins yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4. Toxicol. Lett. 2011, 207(2):167-172.
-
(2011)
Toxicol. Lett.
, vol.207
, Issue.2
, pp. 167-172
-
-
Lopez, A.M.1
-
145
-
-
0023909274
-
Decreased levels of protein kinase C in Alzheimer brain
-
Cole G., et al. Decreased levels of protein kinase C in Alzheimer brain. Brain Res. 1988, 452(1-2):165-174.
-
(1988)
Brain Res.
, vol.452
, Issue.1-2
, pp. 165-174
-
-
Cole, G.1
-
146
-
-
0028429943
-
Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization
-
Huang Y.Y., Kandel E.R. Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization. Learn. Mem. 1994, 1(1):74-82.
-
(1994)
Learn. Mem.
, vol.1
, Issue.1
, pp. 74-82
-
-
Huang, Y.Y.1
Kandel, E.R.2
-
147
-
-
0027203084
-
Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons
-
Frey U., Huang Y.Y., Kandel E.R. Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons. Science 1993, 260(5114):1661-1664.
-
(1993)
Science
, vol.260
, Issue.5114
, pp. 1661-1664
-
-
Frey, U.1
Huang, Y.Y.2
Kandel, E.R.3
-
148
-
-
77956265004
-
Profile for amyloid-beta and tau expression in primary cortical cultures from 3xTg-AD mice
-
Vale C., et al. Profile for amyloid-beta and tau expression in primary cortical cultures from 3xTg-AD mice. Cell Mol. Neurobiol. 2010, 30(4):577-590.
-
(2010)
Cell Mol. Neurobiol.
, vol.30
, Issue.4
, pp. 577-590
-
-
Vale, C.1
-
149
-
-
84907500303
-
Use of yessotoxin and analogs and derivatives thereof for treating and/or preventing neurodegenerative diseases linked to tau and beta amyloid
-
Patent, PCT/ES2011/070078(ES P201030162 8): WO 2011/095668 A1.
-
L.M. Botana, E. Alonso, C. Vale, Use of yessotoxin and analogs and derivatives thereof for treating and/or preventing neurodegenerative diseases linked to tau and beta amyloid. Patent, 2011. PCT/ES2011/070078(ES P201030162 8): p. WO 2011/095668 A1.
-
(2011)
-
-
Botana, L.M.1
Alonso, E.2
Vale, C.3
|