Modulation of cytosolic calcium levels of human lymphocytes by yessotoxin, a novel marine phycotoxin

Biochemical Pharmacology

Volumn 61, Issue 7, 2001, Pages 827-833

  De la Rosa, Laura A ^a   Alfonso, Amparo ^a   Vilario, Natalia ^a   Vieytes, Mercedes R ^a   Botana, Luis M ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Calcium channels; Capacitative calcium entry; Okadaic acid; Thapsigargin; Yessotoxin

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; CALCIUM; NIFEDIPINE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE; THAPSIGARGIN; TOXIN; UNCLASSIFIED DRUG; YESSOTOXIN;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME INHIBITION; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; LYMPHOCYTE; PRIORITY JOURNAL; SHELLFISH;

BIOLOGICAL TRANSPORT; CALCIUM; CYTOSOL; ENZYME INHIBITORS; ETHERS, CYCLIC; HOMEOSTASIS; HUMANS; LYMPHOCYTES; MOLLUSK VENOMS; OXOCINS; SIGNAL TRANSDUCTION; THAPSIGARGIN;

EID: 0035313618     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00549-4     Document Type: Article

References (43)

1. Isolation and structure of yessotoxin, a novel polyether compound implicated in diarrhetic shellfish poisoning
2. Occurrence of a new type of shellfish poisoning in the Tohoku Distric
3. Toxicologic evaluation of yessotoxin
4. Histopathological studies on experimental marine toxin poisoning - 5. The effects in mice of yessotoxin isolated from Patinopecten yessoensis and of a desulfated derivative
5. Phycotoxins
6. Identification of Protoceratium reticulatum as the biogenetic origin of yessotoxin
7. Two new analogues of yessotoxin, homoyessotoxin and 45-hydroxyhomoyessotoxin, isolated from mussels of the Adriatic Sea
8. High levels of yessotoxin in mussels and presence of yessotoxin and homoyessotoxin in dinoflagellates of the Adriatic Sea
9. Depolarizing action of a red-tide dinoflagellate brevetoxin on axonal membranes
10. Interaction of brevetoxin A with a new receptor site on the sodium channel
11. Brevetoxins, unique activators of voltage-sensitive sodium channels, bind to specific sites in rat brain synaptosomes
12. Yessotoxin in mussels of the northern Adriatic Sea
13. Isolation of 45-hydroxyyessotoxin from mussels of the Adriatic Sea
14. 2+ and membrane potential in lymphocytes
15. ++ indicators with greatly improved fluorescence properties
16. Smooth muscle myosin phosphatase inhibition and force enhancement by black sponge toxin
17. Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics
18. Apparent "activation" of protein kinases by okadaic acid class tumor promoters
19. Protein phosphorylation and signal transduction
20. Modulation of ion channels by protein phosphorylation and dephosphorylation
21. Potassium and calcium channels in lymphocytes
22. Signal transduction by T-cell receptors: Mobilization of Ca and regulation of Ca-dependent effector molecules
23. A model for receptor-regulated calcium entry
24. Capacitative calcium entry revisited
25. Calcium release-activated calcium current in rat mast cells
26. 2+ stores
27. 2+-ATPase inhibitors
28. The calcium current activated by T cell receptor and store depletion in human lymphocytes is absent in a primary immunodeficiency
29. 2+ entry mechanisms coexist in Jurkat T cells during T cell receptor antigen activation
30. 2+ entry in human lymphocytes whereas ICRAC has no apparent role
31. Non-specific effects of calcium entry antagonists in mast cells
32. 2+ transport pathways in thymic lymphocytes by econazole, miconazole, and SKF 96365
33. Estradiol binding to cell surface raises cytosolic free calcium in T cells
34. 5-Hydroxytryptamine-induced calcium-channel gating in rainbow trout (Oncorhynchus mykiss) peripheral blood lymphocytes
35. Lymphocyte activation and phospholipid pathways. 31P magnetic resonance studies
36. 2+ response and interleukin-2 production in Jurkat cells
37. 2+ channel activator candidate
38. Maitotoxin-induced intracellular calcium rise in PC12 cells: Involvement of dyhydropyridine-sensitive and omega-conotoxin-sensitive calcium channels and phosphoinositide breakdown
39. 2+ influx in rat glioma C6 cells by brevetoxins and synthetic fragments of maitotoxin
40. Voltage-regulated sodium channel molecules
41. G-protein regulation of capacitative calcium entry may be mediated by protein kinases A and C in Xenopus oocytes
42. 2+ entry in cultured rat cerebellar astrocytes
43. 2+-inhibited adenylyl cyclase in cardiac tissue