메뉴 건너뛰기




Volumn 86, Issue 13, 2008, Pages 2952-2962

Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: Involvement of the c-Jun N-terminal kinase

Author keywords

Azaspiracid; Azaspiracid 2; Azaspiracid 2 methyl ester; Cerebellar granule cell; Cytotoxicity; JNK; MAPK

Indexed keywords

AZASPIRACID; AZASPIRACID 2; AZASPIRACID 2 METHYL ESTER; CARBOXYLIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 57049171334     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21731     Document Type: Article
Times cited : (16)

References (36)
  • 1
    • 0037437764 scopus 로고    scopus 로고
    • Yessotoxin, a novel phycotoxin, activates phosphodiesterase activity. Effect of yessotoxin on cAMP levels in human lymphocytes
    • Alfonso A, de la Rosa L, Vieytes MR, Yasumoto T, Botana LM. 2003. Yessotoxin, a novel phycotoxin, activates phosphodiesterase activity. Effect of yessotoxin on cAMP levels in human lymphocytes. Biochem Pharmacol 65:193-208.
    • (2003) Biochem Pharmacol , vol.65 , pp. 193-208
    • Alfonso, A.1    de la Rosa, L.2    Vieytes, M.R.3    Yasumoto, T.4    Botana, L.M.5
  • 3
    • 0034667705 scopus 로고    scopus 로고
    • Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons
    • Coffey ET, Hongisto V, Dickens M, Davis RJ, Courtney MJ. 2000. Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons. J Neurosci 20:7602-7613.
    • (2000) J Neurosci , vol.20 , pp. 7602-7613
    • Coffey, E.T.1    Hongisto, V.2    Dickens, M.3    Davis, R.J.4    Courtney, M.J.5
  • 4
    • 0011486518 scopus 로고    scopus 로고
    • Cerebellar granule cells as a model to study mechanisms of neuronal apoptosis or survival in vivo and in vitro
    • Contestabile A. 2002. Cerebellar granule cells as a model to study mechanisms of neuronal apoptosis or survival in vivo and in vitro. Cerebellum 1:41-55.
    • (2002) Cerebellum , vol.1 , pp. 41-55
    • Contestabile, A.1
  • 5
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ. 2000. Signal transduction by the JNK group of MAP kinases. Cell 103:239-252.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 6
    • 13844262643 scopus 로고    scopus 로고
    • The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways
    • Guan QH, Pei DS, Zhang QG, Hao ZB, Xu TL, Zhang GY. 2005. The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways. Brain Res 1035:51-59.
    • (2005) Brain Res , vol.1035 , pp. 51-59
    • Guan, Q.H.1    Pei, D.S.2    Zhang, Q.G.3    Hao, Z.B.4    Xu, T.L.5    Zhang, G.Y.6
  • 7
    • 0033974774 scopus 로고    scopus 로고
    • Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland
    • Ito E, Satake M, Ofuji K, Kurita N, McMahon T, James K, Yasumoto T. 2000. Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland. Toxicon 38:917-930.
    • (2000) Toxicon , vol.38 , pp. 917-930
    • Ito, E.1    Satake, M.2    Ofuji, K.3    Kurita, N.4    McMahon, T.5    James, K.6    Yasumoto, T.7
  • 8
    • 0036027438 scopus 로고    scopus 로고
    • Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels
    • Ito E, Satake M, Ofuji K, Higashi M, Harigaya K, McMahon T, Yasumoto T. 2002. Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels. Toxicon 40:193-203.
    • (2002) Toxicon , vol.40 , pp. 193-203
    • Ito, E.1    Satake, M.2    Ofuji, K.3    Higashi, M.4    Harigaya, K.5    McMahon, T.6    Yasumoto, T.7
  • 10
    • 0037305986 scopus 로고    scopus 로고
    • Ubiquitous "benign" alga emerges as the cause of shellfish contamination responsible for the human toxic syndrome, azaspiracid poisoning
    • James KJ, Moroney C, Roden C, Satake M, Yasumoto T, Lehane M, Furey A. 2003a. Ubiquitous "benign" alga emerges as the cause of shellfish contamination responsible for the human toxic syndrome, azaspiracid poisoning. Toxicon 41:145-151.
    • (2003) Toxicon , vol.41 , pp. 145-151
    • James, K.J.1    Moroney, C.2    Roden, C.3    Satake, M.4    Yasumoto, T.5    Lehane, M.6    Furey, A.7
  • 11
    • 0037355392 scopus 로고    scopus 로고
    • Detection of five new hydroxyl analogues of azaspiracids in shellfish using multiple tandem mass spectrometry
    • James KJ, Sierra MD, Lehane M, Brana Magdalena A, Furey A. 2003b. Detection of five new hydroxyl analogues of azaspiracids in shellfish using multiple tandem mass spectrometry. Toxicon 41:277-283.
    • (2003) Toxicon , vol.41 , pp. 277-283
    • James, K.J.1    Sierra, M.D.2    Lehane, M.3    Brana Magdalena, A.4    Furey, A.5
  • 12
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis JM, Avruch J. 2001. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81:807-869.
    • (2001) Physiol Rev , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 15
    • 0042035641 scopus 로고    scopus 로고
    • Total synthesis of the proposed azaspiracid-1 structure, part 2: Coupling of the C1-C20, C21-C27, and C28-C40 fragments and completion of the synthesis
    • Nicolaou KC, Chen DY, Li Y, Qian W, Ling T, Vyskocil S, Koftis TV, Govindasamy M, Uesaka N. 2003. Total synthesis of the proposed azaspiracid-1 structure, part 2: coupling of the C1-C20, C21-C27, and C28-C40 fragments and completion of the synthesis. Angew Chem Int Ed Engl 42:3649-3653.
    • (2003) Angew Chem Int Ed Engl , vol.42 , pp. 3649-3653
    • Nicolaou, K.C.1    Chen, D.Y.2    Li, Y.3    Qian, W.4    Ling, T.5    Vyskocil, S.6    Koftis, T.V.7    Govindasamy, M.8    Uesaka, N.9
  • 22
    • 0033390733 scopus 로고    scopus 로고
    • Two analogs of azaspiracid isolated from mussels, Mytilus edulis, involved in human intoxication in Ireland
    • Ofuji K, Satake M, McMahon T, Silke J, James KJ, Naoki H, Oshima Y, Yasumoto T. 1999a. Two analogs of azaspiracid isolated from mussels, Mytilus edulis, involved in human intoxication in Ireland. Nat Toxins 7:99-102.
    • (1999) Nat Toxins , vol.7 , pp. 99-102
    • Ofuji, K.1    Satake, M.2    McMahon, T.3    Silke, J.4    James, K.J.5    Naoki, H.6    Oshima, Y.7    Yasumoto, T.8
  • 23
    • 0033286128 scopus 로고    scopus 로고
    • A sensitive and specific determination method for azaspiracids by liquid chromatography mass spectrometry
    • Ofuji K, Satake M, Oshima Y, McMahon T, James KJ, Yasumoto T. 1999b. A sensitive and specific determination method for azaspiracids by liquid chromatography mass spectrometry. Nat Toxins 7:247-250.
    • (1999) Nat Toxins , vol.7 , pp. 247-250
    • Ofuji, K.1    Satake, M.2    Oshima, Y.3    McMahon, T.4    James, K.J.5    Yasumoto, T.6
  • 24
    • 0035289355 scopus 로고    scopus 로고
    • Structures of azaspiracid analogs, azaspiracid-4 and azaspiracid-5, causative toxins of azaspiracid poisoning in Europe
    • Ofuji K, Satake M, McMahon T, James KJ, Naoki H, Oshima Y, Yasumoto T. 2001. Structures of azaspiracid analogs, azaspiracid-4 and azaspiracid-5, causative toxins of azaspiracid poisoning in Europe. Biosci Biotechnol Biochem 65:740-742.
    • (2001) Biosci Biotechnol Biochem , vol.65 , pp. 740-742
    • Ofuji, K.1    Satake, M.2    McMahon, T.3    James, K.J.4    Naoki, H.5    Oshima, Y.6    Yasumoto, T.7
  • 26
    • 0032582026 scopus 로고    scopus 로고
    • Azaspiracid, a new marine toxin having unique spiro ring assemblies, isolated from Irish mussels, Mytilus edulis
    • Satake M, Ofuji K, Naoki H, James KJ, Furey A, McMahon T, Silke J, Yasumoto T. 1998. Azaspiracid, a new marine toxin having unique spiro ring assemblies, isolated from Irish mussels, Mytilus edulis. J Am Chem Soc 120:9967-9968.
    • (1998) J Am Chem Soc , vol.120 , pp. 9967-9968
    • Satake, M.1    Ofuji, K.2    Naoki, H.3    James, K.J.4    Furey, A.5    McMahon, T.6    Silke, J.7    Yasumoto, T.8
  • 27
    • 0022323906 scopus 로고
    • Cultured neurons as model systems for biochemical and pharmacological studies on receptors for neurotransmitter amino acids
    • Schousboe A, Drejer J, Hansen GH, Meier E. 1985. Cultured neurons as model systems for biochemical and pharmacological studies on receptors for neurotransmitter amino acids. Dev Neurosci 7:252-262.
    • (1985) Dev Neurosci , vol.7 , pp. 252-262
    • Schousboe, A.1    Drejer, J.2    Hansen, G.H.3    Meier, E.4
  • 28
    • 0001607156 scopus 로고
    • Preparation of primary cultures of mouse (rat) cerebellar granule cells
    • Shahar A, de Vellis J, Vernadakis A, Haber B, editors, New York: Alan R Liss. p
    • Schousboe A, Meier E, Drejer J, Hertz L. 1989. Preparation of primary cultures of mouse (rat) cerebellar granule cells. In: Shahar A, de Vellis J, Vernadakis A, Haber B, editors. A dissection and tissue culture manual of the nervous system. New York: Alan R Liss. p 203-206.
    • (1989) A dissection and tissue culture manual of the nervous system , pp. 203-206
    • Schousboe, A.1    Meier, E.2    Drejer, J.3    Hertz, L.4
  • 29
    • 0035166616 scopus 로고    scopus 로고
    • The neuronal MAP kinase cascade: A biochemical signal integration system subserving synaptic plasticity and memory
    • Sweatt JD. 2001. The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J Neurochem 76:1-10.
    • (2001) J Neurochem , vol.76 , pp. 1-10
    • Sweatt, J.D.1
  • 33
    • 33744913282 scopus 로고    scopus 로고
    • Modulation of calcium entry and glutamate release in cultured cerebellar granule cells by palytoxin
    • Vale C, Alfonso A, Sunol C, Vieytes MR, Botana LM. 2006. Modulation of calcium entry and glutamate release in cultured cerebellar granule cells by palytoxin. J Neurosci Res 83:1393-1406.
    • (2006) J Neurosci Res , vol.83 , pp. 1393-1406
    • Vale, C.1    Alfonso, A.2    Sunol, C.3    Vieytes, M.R.4    Botana, L.M.5
  • 35
    • 33846404512 scopus 로고    scopus 로고
    • Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study
    • Vale C, Nicolaou KC, Frederick MO, Gomez-Limia B, Alfonso A, Vieytes MR, Botana LM. 2007b. Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study. J Med Chem 50:356-363.
    • (2007) J Med Chem , vol.50 , pp. 356-363
    • Vale, C.1    Nicolaou, K.C.2    Frederick, M.O.3    Gomez-Limia, B.4    Alfonso, A.5    Vieytes, M.R.6    Botana, L.M.7
  • 36
    • 0029873997 scopus 로고    scopus 로고
    • Characterization of a chemical anoxia model in cerebellar granule neurons using sodium azide: Protection by nifedipine and MK-801
    • Varming T, Drejer J, Frandsen A, Schousboe A. 1996. Characterization of a chemical anoxia model in cerebellar granule neurons using sodium azide: protection by nifedipine and MK-801. J Neurosci Res 44:40-46.
    • (1996) J Neurosci Res , vol.44 , pp. 40-46
    • Varming, T.1    Drejer, J.2    Frandsen, A.3    Schousboe, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.