메뉴 건너뛰기




Volumn 25, Issue 7, 2012, Pages 1493-1501

Induction of apoptosis pathways in several cell lines following exposure to the marine algal toxin azaspiracid

Author keywords

[No Author keywords available]

Indexed keywords

AZASPIRACID; CASPASE 10; CASPASE 2; CASPASE 3; CASPASE 7; CHEMICAL TERATOGEN; CYTOCHROME C;

EID: 84863924670     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx3001785     Document Type: Article
Times cited : (36)

References (58)
  • 1
    • 0002893951 scopus 로고    scopus 로고
    • Winter toxicity of unknown aetiology in mussels
    • McMahon, T. and Silke, J. (1996) Winter toxicity of unknown aetiology in mussels Harmful Algae News 14, 2
    • (1996) Harmful Algae News , vol.14 , pp. 2
    • McMahon, T.1    Silke, J.2
  • 2
    • 0032582026 scopus 로고    scopus 로고
    • Azaspiracid, a new marine toxin having unique spiro ring assemlies, isolated from Irish mussels, Mytilus edulis
    • Satake, M., Ofuji, K., Naoki, H., James, K. J., Furey, A., McMahon, T., Silke, J., and Yasumoto, T. (1998) Azaspiracid, a new marine toxin having unique spiro ring assemlies, isolated from Irish mussels, Mytilus edulis J. Am. Chem. Soc. 120, 9967-9968
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 9967-9968
    • Satake, M.1    Ofuji, K.2    Naoki, H.3    James, K.J.4    Furey, A.5    McMahon, T.6    Silke, J.7    Yasumoto, T.8
  • 3
    • 77953286406 scopus 로고    scopus 로고
    • Azaspiracid poisoning (AZP) toxins in shellfish: Toxicological and health considerations
    • Furey, A., O'Doherty, S., O'Callaghan, K., Lehane, M., and James, K. J. (2010) Azaspiracid poisoning (AZP) toxins in shellfish: Toxicological and health considerations Toxicon 56, 173-190
    • (2010) Toxicon , vol.56 , pp. 173-190
    • Furey, A.1    O'Doherty, S.2    O'Callaghan, K.3    Lehane, M.4    James, K.J.5
  • 5
    • 61449087418 scopus 로고    scopus 로고
    • Mussel-associated azaspiracid intoxication in the United States
    • Klontz, K. C., Abraham, A., Plakas, S. M., and Dickey, R. W. (2009) Mussel-associated azaspiracid intoxication in the United States Ann. Intern. Med. 150, 361
    • (2009) Ann. Intern. Med. , vol.150 , pp. 361
    • Klontz, K.C.1    Abraham, A.2    Plakas, S.M.3    Dickey, R.W.4
  • 6
    • 46349102246 scopus 로고    scopus 로고
    • Azaspiracid shellfish poisoning: A review on the chemistry, ecology, and toxicology with an emphasis on human health impacts
    • Twiner, M. J., Rehmann, N., Hess, P., and Doucette, G. J. (2008) Azaspiracid shellfish poisoning: A review on the chemistry, ecology, and toxicology with an emphasis on human health impacts Mar. Drugs 6, 39-72
    • (2008) Mar. Drugs , vol.6 , pp. 39-72
    • Twiner, M.J.1    Rehmann, N.2    Hess, P.3    Doucette, G.J.4
  • 7
    • 19344361922 scopus 로고    scopus 로고
    • Teratogenic effects of azaspiracid-1 identified by microinjection of Japanese medaka (Oryzias latipes) embryos
    • Colman, J. R., Twiner, M. J., Hess, P., McMahon, T., Satake, M., Yasumoto, T., Doucette, G. J., and Ramsdell, J. S. (2005) Teratogenic effects of azaspiracid-1 identified by microinjection of Japanese medaka (Oryzias latipes) embryos Toxicon 45, 881-890
    • (2005) Toxicon , vol.45 , pp. 881-890
    • Colman, J.R.1    Twiner, M.J.2    Hess, P.3    McMahon, T.4    Satake, M.5    Yasumoto, T.6    Doucette, G.J.7    Ramsdell, J.S.8
  • 9
    • 0037355392 scopus 로고    scopus 로고
    • Detection of five new hydroxyl analogues of azaspiracids in shellfish using multiple tandem mass spectrometry
    • James, K. J., Sierra, M. D., Lehane, M., Braña Magdalena, A., and Furey, A. (2003) Detection of five new hydroxyl analogues of azaspiracids in shellfish using multiple tandem mass spectrometry Toxicon 41, 277-283
    • (2003) Toxicon , vol.41 , pp. 277-283
    • James, K.J.1    Sierra, M.D.2    Lehane, M.3    Braña Magdalena, A.4    Furey, A.5
  • 10
    • 39749120849 scopus 로고    scopus 로고
    • Discovery of new analogs of the marine biotoxin azaspiracid in blue mussels (Mytilus edulis) by ultra-performance liquid chromatography/tandem mass spectrometry
    • Rehmann, N., Hess, P., and Quilliam, M. (2008) Discovery of new analogs of the marine biotoxin azaspiracid in blue mussels (Mytilus edulis) by ultra-performance liquid chromatography/tandem mass spectrometry Rapid Commun. Mass Spectrom. 22, 549-558
    • (2008) Rapid Commun. Mass Spectrom. , vol.22 , pp. 549-558
    • Rehmann, N.1    Hess, P.2    Quilliam, M.3
  • 11
    • 57649228049 scopus 로고    scopus 로고
    • Characterization of azaspiracids in plankton size-fractions and isolation of an azaspiracid-producing dinoflagellate from the North Sea
    • Krock, B., Tillmann, U., John, U., and Cembella, A. D. (2009) Characterization of azaspiracids in plankton size-fractions and isolation of an azaspiracid-producing dinoflagellate from the North Sea Harmful Algae 8, 254-263
    • (2009) Harmful Algae , vol.8 , pp. 254-263
    • Krock, B.1    Tillmann, U.2    John, U.3    Cembella, A.D.4
  • 12
    • 69249153420 scopus 로고    scopus 로고
    • Azadinium spinosum gen. et sp. nov. (Dinophyceae) identified as a primary producer of azaspiracid toxins
    • Tillmann, U., Elbrächter, M., Krock, B., John, U., and Cembella, A. (2009) Azadinium spinosum gen. et sp. nov. (Dinophyceae) identified as a primary producer of azaspiracid toxins Eur. J. Phycol. 44, 63-79
    • (2009) Eur. J. Phycol. , vol.44 , pp. 63-79
    • Tillmann, U.1    Elbrächter, M.2    Krock, B.3    John, U.4    Cembella, A.5
  • 13
    • 0036027438 scopus 로고    scopus 로고
    • Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels
    • Ito, E., Satake, M., Ofuji, K., Higashi, M., Harigaya, K., McMahon, T., and Yasumoto, T. (2002) Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels Toxicon 40, 193-203
    • (2002) Toxicon , vol.40 , pp. 193-203
    • Ito, E.1    Satake, M.2    Ofuji, K.3    Higashi, M.4    Harigaya, K.5    McMahon, T.6    Yasumoto, T.7
  • 14
    • 0033974774 scopus 로고    scopus 로고
    • Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland
    • Ito, E., Satake, M., Ofuji, K., Kurita, N., McMahon, T., James, K., and Yasumoto, T. (2000) Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland Toxicon 38, 917-930
    • (2000) Toxicon , vol.38 , pp. 917-930
    • Ito, E.1    Satake, M.2    Ofuji, K.3    Kurita, N.4    McMahon, T.5    James, K.6    Yasumoto, T.7
  • 15
    • 0003096532 scopus 로고    scopus 로고
    • Acute pathological changes in mice caused by crude extracts of novel toxins isolated from Irish mussels
    • (Reguera, B. Blanco, J. Fernandez, M. L. and Wyatt, T. Eds.) Xunta de Galicia and Intergovernmental Oceanographic Commission of UNESCO, Santiago de Compostela
    • Ito, E., Terao, K., McMahon, T., Silke, J., and Yasumoto, T. (1998) Acute pathological changes in mice caused by crude extracts of novel toxins isolated from Irish mussels. In Harmful Algae (Reguera, B., Blanco, J., Fernandez, M. L., and Wyatt, T., Eds.) pp 588-589, Xunta de Galicia and Intergovernmental Oceanographic Commission of UNESCO, Santiago de Compostela.
    • (1998) Harmful Algae , pp. 588-589
    • Ito, E.1    Terao, K.2    McMahon, T.3    Silke, J.4    Yasumoto, T.5
  • 18
    • 33846404512 scopus 로고    scopus 로고
    • Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study
    • Vale, C., Nicolaou, K. C., Frederick, M. O., Gomez-Limia, B., Alfonso, A., Vieytes, M. R., and Botana, L. M. (2007) Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study J. Med. Chem. 50, 356-363
    • (2007) J. Med. Chem. , vol.50 , pp. 356-363
    • Vale, C.1    Nicolaou, K.C.2    Frederick, M.O.3    Gomez-Limia, B.4    Alfonso, A.5    Vieytes, M.R.6    Botana, L.M.7
  • 19
    • 77951528520 scopus 로고    scopus 로고
    • Involvement of caspase activation in azaspiracid-induced neurotoxicity in neocortical neurons
    • Cao, Z., LePage, K. T., Frederick, M. O., Nicolaou, K. C., and Murray, T. F. (2010) Involvement of caspase activation in azaspiracid-induced neurotoxicity in neocortical neurons Toxicol. Sci. 114, 323-334
    • (2010) Toxicol. Sci. , vol.114 , pp. 323-334
    • Cao, Z.1    Lepage, K.T.2    Frederick, M.O.3    Nicolaou, K.C.4    Murray, T.F.5
  • 20
    • 34250021053 scopus 로고    scopus 로고
    • Irreversible cytoskeletal disarrangement is independent of caspase activation during in vitro azaspiracid toxicity in human neuroblastoma cells
    • Vilariño, N., Nicolaou, K. C., Frederick, M. O., Vieytes, M. R., and Botana, L. M. (2007) Irreversible cytoskeletal disarrangement is independent of caspase activation during in vitro azaspiracid toxicity in human neuroblastoma cells Biochem. Pharmacol. 74, 327-335
    • (2007) Biochem. Pharmacol. , vol.74 , pp. 327-335
    • Vilariño, N.1    Nicolaou, K.C.2    Frederick, M.O.3    Vieytes, M.R.4    Botana, L.M.5
  • 21
    • 56849120307 scopus 로고    scopus 로고
    • Marine toxins and the cytoskeleton: Azaspiracids
    • Vilariño, N. (2008) Marine toxins and the cytoskeleton: azaspiracids FEBS J. 275, 6075-6081
    • (2008) FEBS J. , vol.275 , pp. 6075-6081
    • Vilariño, N.1
  • 27
    • 77955874348 scopus 로고    scopus 로고
    • Azaspiracid-1 inhibits endocytosis of plasma membrane proteins in epithelial cells
    • Bellocci, M., Sala, G. L., Callegari, F., and Rossini, G. P. (2010) Azaspiracid-1 inhibits endocytosis of plasma membrane proteins in epithelial cells Toxicol. Sci. 117, 109-121
    • (2010) Toxicol. Sci. , vol.117 , pp. 109-121
    • Bellocci, M.1    Sala, G.L.2    Callegari, F.3    Rossini, G.P.4
  • 28
    • 33846512435 scopus 로고    scopus 로고
    • Azaspiracid-1 alters the E-cadherin pool in epithelial cells
    • Ronzitti, G., Hess, P., Rehmann, N., and Rossini, G. P. (2007) Azaspiracid-1 alters the E-cadherin pool in epithelial cells Toxicol. Sci. 95, 427-435
    • (2007) Toxicol. Sci. , vol.95 , pp. 427-435
    • Ronzitti, G.1    Hess, P.2    Rehmann, N.3    Rossini, G.P.4
  • 30
    • 84866402236 scopus 로고    scopus 로고
    • The marine algal toxin azaspiracid is an open state blocker of hERG potassium channels
    • (manuscript under review)
    • Twiner, M. J., Doucette, G. J., Rasky, A., Huang, X.-P., Roth, B. L., and Sanguinetti, M. C. (2012) The marine algal toxin azaspiracid is an open state blocker of hERG potassium channels. Toxicol. Sci. (manuscript under review).
    • (2012) Toxicol. Sci.
    • Twiner, M.J.1    Doucette, G.J.2    Rasky, A.3    Huang, X.-P.4    Roth, B.L.5    Sanguinetti, M.C.6
  • 31
    • 0034641918 scopus 로고
    • The biochemistry of apoptosis
    • Hengartner, M. D. (1992) The biochemistry of apoptosis Nature 407, 770-776
    • (1992) Nature , vol.407 , pp. 770-776
    • Hengartner, M.D.1
  • 32
    • 0031736004 scopus 로고    scopus 로고
    • Biochemical determinants of apoptosis and necrosis
    • McConkey, D. J. (1998) Biochemical determinants of apoptosis and necrosis Toxicol. Lett. 99, 157-168
    • (1998) Toxicol. Lett. , vol.99 , pp. 157-168
    • McConkey, D.J.1
  • 33
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: A review of programmed cell death
    • Elmore, S. (2007) Apoptosis: A review of programmed cell death Toxicol. Pathol. 35, 495-516
    • (2007) Toxicol. Pathol. , vol.35 , pp. 495-516
    • Elmore, S.1
  • 35
    • 84858316763 scopus 로고    scopus 로고
    • Improved isolation procedure for azaspiracids from shellfish, structural elucidation of azaspiracid-6, and stability studies
    • Kilcoyne, J., Keogh, A., Clancy, G., Le Blanc, P., Burton, I., Quilliam, M., Hess, P., and Miles, C. O. (2012) Improved isolation procedure for azaspiracids from shellfish, structural elucidation of azaspiracid-6, and stability studies J. Agric. Food Chem. 60, 2447-2455
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 2447-2455
    • Kilcoyne, J.1    Keogh, A.2    Clancy, G.3    Le Blanc, P.4    Burton, I.5    Quilliam, M.6    Hess, P.7    Miles, C.O.8
  • 36
    • 84858694033 scopus 로고    scopus 로고
    • Comparative effects of the marine algal toxins azaspiracid-1, -2, and -3 on Jurkat T lymphocyte cells
    • Twiner, M. J., El-Ladki, R., Kilcoyne, J., and Doucette, G. J. (2012) Comparative effects of the marine algal toxins azaspiracid-1, -2, and -3 on Jurkat T lymphocyte cells Chem. Res. Toxicol. 25, 747-754
    • (2012) Chem. Res. Toxicol. , vol.25 , pp. 747-754
    • Twiner, M.J.1    El-Ladki, R.2    Kilcoyne, J.3    Doucette, G.J.4
  • 37
    • 0029738086 scopus 로고    scopus 로고
    • Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: Evidence for cell cycle-independent toxicity
    • Morris, E. J. and Geller, H. M. (1996) Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: Evidence for cell cycle-independent toxicity J. Cell Biol. 134, 757-770
    • (1996) J. Cell Biol. , vol.134 , pp. 757-770
    • Morris, E.J.1    Geller, H.M.2
  • 38
    • 7144248725 scopus 로고
    • Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata
    • Wall, M. E., Wani, M. C., Cook, C. E., Palmer, K. H., McPhail, A. T., and Sim, G. A. (1966) Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata J. Am. Chem. Soc. 88, 3888-3890
    • (1966) J. Am. Chem. Soc. , vol.88 , pp. 3888-3890
    • Wall, M.E.1    Wani, M.C.2    Cook, C.E.3    Palmer, K.H.4    McPhail, A.T.5    Sim, G.A.6
  • 40
    • 79961243580 scopus 로고    scopus 로고
    • Total synthesis and PPase inhibition of dinophysistoxin-2 and 2-epi-dinophysistoxin-2
    • Pang, Y., Fang, C., Twiner, M. J., Miles, C. O., and Forsyth, C. J. (2011) Total synthesis and PPase inhibition of dinophysistoxin-2 and 2-epi-dinophysistoxin-2 Angew. Chem., Int. Ed. 50, 7631-7635
    • (2011) Angew. Chem., Int. Ed. , vol.50 , pp. 7631-7635
    • Pang, Y.1    Fang, C.2    Twiner, M.J.3    Miles, C.O.4    Forsyth, C.J.5
  • 42
    • 75249087776 scopus 로고    scopus 로고
    • Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons
    • Vale, C., Nicolaou, K. C., Frederick, M. O., Vieytes, M. R., and Botana, L. M. (2010) Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons Toxicol. Sci. 113, 158-168
    • (2010) Toxicol. Sci. , vol.113 , pp. 158-168
    • Vale, C.1    Nicolaou, K.C.2    Frederick, M.O.3    Vieytes, M.R.4    Botana, L.M.5
  • 46
    • 77955135238 scopus 로고    scopus 로고
    • The role of caspase-2 in stress-induced apoptosis
    • Bouchier-Hayes, L. (2010) The role of caspase-2 in stress-induced apoptosis J. Cell. Mol. Med. 14, 1212-1224
    • (2010) J. Cell. Mol. Med. , vol.14 , pp. 1212-1224
    • Bouchier-Hayes, L.1
  • 47
    • 0037134495 scopus 로고    scopus 로고
    • Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria
    • Guo, Y., Srinivasula, S. M., Druilhe, A., Fernandes-Alnemri, T., and Alnemri, E. S. (2002) Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria J. Biol. Chem. 277, 13430-13437
    • (2002) J. Biol. Chem. , vol.277 , pp. 13430-13437
    • Guo, Y.1    Srinivasula, S.M.2    Druilhe, A.3    Fernandes-Alnemri, T.4    Alnemri, E.S.5
  • 48
    • 0035877605 scopus 로고    scopus 로고
    • Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3
    • Paroni, G., Henderson, C., Schneider, C., and Brancolini, C. (2001) Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3 J. Biol. Chem. 276, 21907-21915
    • (2001) J. Biol. Chem. , vol.276 , pp. 21907-21915
    • Paroni, G.1    Henderson, C.2    Schneider, C.3    Brancolini, C.4
  • 50
    • 0032493910 scopus 로고    scopus 로고
    • Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
    • Kuida, K., Haydar, T., Kuan, C.-Y., Gu, Y., Taya, C., Karasuyama, H., Su, M., Rakic, P., and Flavell, R. (1998) Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9 Cell 94, 325-337
    • (1998) Cell , vol.94 , pp. 325-337
    • Kuida, K.1    Haydar, T.2    Kuan, C.-Y.3    Gu, Y.4    Taya, C.5    Karasuyama, H.6    Su, M.7    Rakic, P.8    Flavell, R.9
  • 51
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf 3/caspase 9 complex initiates an apoptotic protease cascade
    • Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S., Ahmad, M., Alnemri, E., and Wang, X. (1997) Cytochrome c and dATP-dependent formation of Apaf 3/caspase 9 complex initiates an apoptotic protease cascade Cell 91, 479-489
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.4    Ahmad, M.5    Alnemri, E.6    Wang, X.7
  • 52
    • 0030741528 scopus 로고    scopus 로고
    • Cytochrome c activation of CCP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system
    • Kluck, R., Martin, S., Hoffman, B., Zhou, J., Green, D., and Newmeyer, D. (1997) Cytochrome c activation of CCP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system EMBO J. 16, 4639-4649
    • (1997) EMBO J. , vol.16 , pp. 4639-4649
    • Kluck, R.1    Martin, S.2    Hoffman, B.3    Zhou, J.4    Green, D.5    Newmeyer, D.6
  • 53
    • 4544274852 scopus 로고    scopus 로고
    • Induction of anoikis by doxazosin in prostate cancer cells is associated with activation of caspase-3 and a reduction of focal adhesion kinase
    • Walden, P. D., Globina, Y., and Nieder, A. (2004) Induction of anoikis by doxazosin in prostate cancer cells is associated with activation of caspase-3 and a reduction of focal adhesion kinase Urol. Res. 32, 261-265
    • (2004) Urol. Res. , vol.32 , pp. 261-265
    • Walden, P.D.1    Globina, Y.2    Nieder, A.3
  • 56
    • 0029821825 scopus 로고    scopus 로고
    • Cytotoxicity of macrolide antibiotics in a cultured human liver cell line Matti Viluksela
    • Viluksela, M., Vainio, P. J., and Tuominen, R. K. (1996) Cytotoxicity of macrolide antibiotics in a cultured human liver cell line Matti Viluksela J. Antimicrob. Chemother. 38, 465-473
    • (1996) J. Antimicrob. Chemother. , vol.38 , pp. 465-473
    • Viluksela, M.1    Vainio, P.J.2    Tuominen, R.K.3
  • 57
    • 0031443822 scopus 로고    scopus 로고
    • Apoptosis and Necrosis in Toxicology: A Continuum or Distinct Modes of Cell Death?
    • Raffray, M. and Cohen, G. M. (1997) Apoptosis and Necrosis in Toxicology: A Continuum or Distinct Modes of Cell Death? Pharmac. Ther. 75, 153-177
    • (1997) Pharmac. Ther. , vol.75 , pp. 153-177
    • Raffray, M.1    Cohen, G.M.2
  • 58
    • 79952792272 scopus 로고    scopus 로고
    • Programmed cell death: Apoptosis meets necrosis
    • Peter, M. E. (2011) Programmed cell death: Apoptosis meets necrosis Nature 471, 310-312
    • (2011) Nature , vol.471 , pp. 310-312
    • Peter, M.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.