Transcriptional profiling and inhibition of cholesterol biosynthesis in human T lymphocyte cells by the marine toxin azaspiracid

Genomics

Volumn 91, Issue 3, 2008, Pages 289-300

  Twiner, Michael J ^a   Ryan, James C ^a   Morey, Jeanine S ^a   Smith, Kent J ^b   Hammad, Samar M ^b   Van Dolah, Frances M ^a   Hess, Philipp ^c   McMahon, Terry ^c   Satake, Masayuki ^d   Yasumoto, Takeshi ^e   Doucette, Gregory J ^a  

^a CENTER FOR COASTAL ENVIRONMENTAL HEALTH AND BIOMOLECULAR RESEARCH   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c MARINE INSTITUTE   (Ireland)

^d TOHOKU UNIVERSITY   (Japan)

^e JAPAN FOOD RESEARCH LABORATORIES   (Japan)

Author keywords

Azaspiracid 1; Cholesterol; Fatty acid; Gene expression; Harmful algal bloom; Immunoblot; Low density lipoprotein receptor; Microarray; Shellfish toxin; T lymphocyte cells

Indexed keywords

AZASPIRACID; CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MARINE TOXIN; MEMBRANE PROTEIN; MEMBRANE RECEPTOR; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CANADA; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DNA MICROARRAY; DRUG MECHANISM; EUROPE; GASTROINTESTINAL ABSORPTION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MOROCCO; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHELLFISH; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION REGULATION;

ANIMALS; CHOLESTEROL; CHROMOSOME MAPPING; FATTY ACIDS; FOOD POISONING; GENE EXPRESSION; GENE EXPRESSION PROFILING; GLUCAGON; HUMANS; INSULIN; JURKAT CELLS; MARINE TOXINS; MULTIGENE FAMILY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, LDL; SHELLFISH; SIGNAL TRANSDUCTION; SPIRO COMPOUNDS; T-LYMPHOCYTES; WNT PROTEINS;

ALGAE;

EID: 39149132818     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2007.10.015     Document Type: Article

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