New technologies provide quantum changes in the scale, speed, and success of SELEX methods and aptamer characterization

Molecular Therapy Nucleic Acids

Volumn 3, Issue , 2014, Pages

  Ozer, Abdullah ^a   Pagano, John M ^a   Lis, John T ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMER; OLIGONUCLEOTIDE; PROTEIN; PYROXYLIN; SPIEGELMER; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; SLOW OFF RATE MODIFIED APTAMER;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMBINATORIAL CHEMISTRY; DATA ANALYSIS; GEL MOBILITY SHIFT ASSAY; HIGH THROUGHPUT SCREENING; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MEDICAL TECHNOLOGY; MICROARRAY ANALYSIS; MICROFLUIDIC ANALYSIS; NONHUMAN; NUCLEIC ACID AMPLIFICATION; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN BINDING; QUANTUM CHEMISTRY; BEAD BASED SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE; CELL SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE; CHEMICAL PROCEDURES; DNA LIBRARY; ELECTROPHORETIC SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE; HIGH THROUGHPUT SEQUENCING; IN VIVO SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE; MICROARRAY BASED SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE; MICROFLUIDIC SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE; MICROSCOPIC BASED SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE; NITROCELLULOSE FILTER BINDING METHOD; NUCLEIC ACID ANALYSIS; SINGLE ROUND SELECTION METHOD; SMALL MOLECULE TARGET SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE;

EID: 84907353413     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1038/mtna.2014.34     Document Type: Review

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