메뉴 건너뛰기




Volumn 15, Issue 8, 2010, Pages 5423-5444

Molecular evolution of functional nucleic acids with chemical modifications

Author keywords

Chemical modification; PCR; PEX; Post SELEX; Random screening; Rational design

Indexed keywords

APTAMER; ENZYME; NUCLEIC ACID;

EID: 77956107133     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules15085423     Document Type: Review
Times cited : (122)

References (88)
  • 1
    • 0022649937 scopus 로고
    • The intervening sequence RNA of Tetrahymena is an enzyme
    • Zaug, A.J.; Cech, T.R. The intervening sequence RNA of Tetrahymena is an enzyme. Science 1986, 231, 470-475.
    • (1986) Science , vol.231 , pp. 470-475
    • Zaug, A.J.1    Cech, T.R.2
  • 2
    • 0021013526 scopus 로고
    • The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
    • Guerrier-Takada, C.; Gardiner, K.; Marsh, T.; Pace, N.; Altman. S. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme. Cell 1983, 35, 849-857.
    • (1983) Cell , vol.35 , pp. 849-857
    • Guerrier-Takada, C.1    Gardiner, K.2    Marsh, T.3    Pace, N.4    Altman., S.5
  • 3
    • 0025332385 scopus 로고
    • Selection in vitro of an RNA enzyme that specifically cleaves singlestranded DNA
    • Robertson, D.L.; Joyce, G.F. Selection in vitro of an RNA enzyme that specifically cleaves singlestranded DNA. Nature 1990, 344, 467-468.
    • (1990) Nature , vol.344 , pp. 467-468
    • Robertson, D.L.1    Joyce, G.F.2
  • 4
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington, A.E.; Szostak, J.W. In vitro Selection of RNA Molecules that Bind Specific Ligands. Nature 1990, 346, 818-822.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.E.1    Szostak, J.W.2
  • 5
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment
    • Tuerk, C.; Gold, L. Systematic evolution of ligands by exponential enrichment. Science 1990, 249, 505-510.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 6
    • 0026575221 scopus 로고
    • Selection of single-stranded DNA molecules that bind and inhibit human thrombin
    • Bock, L.C.; Griffin, L.C.; Latham, J.A.; Vermaas, E.H.; Toole, J.J. Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature 1992, 355, 564-566.
    • (1992) Nature , vol.355 , pp. 564-566
    • Bock, L.C.1    Griffin, L.C.2    Latham, J.A.3    Vermaas, E.H.4    Toole, J.J.5
  • 7
    • 0028030688 scopus 로고
    • Expanding the scope of RNA catalysis
    • Prudent, J.R.; Uno, T.; Schultz, P.G. Expanding the scope of RNA catalysis. Science 1994, 264, 1924-1927.
    • (1994) Science , vol.264 , pp. 1924-1927
    • Prudent, J.R.1    Uno, T.2    Schultz, P.G.3
  • 8
    • 0028911845 scopus 로고
    • In vitro evolution of a self-alkylating ribozyme
    • Wilson, C.; Szostak, J.W. In vitro evolution of a self-alkylating ribozyme. Nature 1995, 374, 777-782.
    • (1995) Nature , vol.374 , pp. 777-782
    • Wilson, C.1    Szostak, J.W.2
  • 10
    • 0031171217 scopus 로고    scopus 로고
    • Rational design of allosteric ribozymes
    • Tang, J.; Breaker, R.R. Rational design of allosteric ribozymes. Chem. Biol. 1997, 4, 453-459.
    • (1997) Chem. Biol. , vol.4 , pp. 453-459
    • Tang, J.1    Breaker, R.R.2
  • 11
    • 0037206833 scopus 로고    scopus 로고
    • Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression
    • Winkler, W.; Nahvi, A.; Breaker, R.R. Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression. Nature 2002, 419, 952-956.
    • (2002) Nature , vol.419 , pp. 952-956
    • Winkler, W.1    Nahvi, A.2    Breaker, R.R.3
  • 13
    • 0000917638 scopus 로고    scopus 로고
    • In vitro selection of catalytic polynucleotides
    • Breaker, R.R. In vitro selection of catalytic polynucleotides. Chem. Rev. 1997, 97, 371-390.
    • (1997) Chem. Rev. , vol.97 , pp. 371-390
    • Breaker, R.R.1
  • 14
    • 0031102380 scopus 로고    scopus 로고
    • Nucleic acid selection and the challenge of combinatorial chemistry
    • Osborne, S.E.; Ellington A.D. Nucleic acid selection and the challenge of combinatorial chemistry. Chem. Rev. 1997, 97, 349-370.
    • (1997) Chem. Rev. , vol.97 , pp. 349-370
    • Osborne, S.E.1    Ellington, A.D.2
  • 15
    • 0032853242 scopus 로고    scopus 로고
    • In vitro selection of functional nucleic acids
    • Wilson, D.W.; Szostak, J.W. In vitro selection of functional nucleic acids. Ann. Rev. Biochem. 1999, 68, 611-648.
    • (1999) Ann. Rev. Biochem. , vol.68 , pp. 611-648
    • Wilson, D.W.1    Szostak, J.W.2
  • 16
    • 0035961485 scopus 로고    scopus 로고
    • Bridging the gap between proteins and nucleic acids: A metal-independent RNAse A mimic with two protein-like functionalities
    • Perrin, D.M.; Garestier, T.; Hélène, C. Bridging the gap between proteins and nucleic acids: a metal-independent RNAse A mimic with two protein-like functionalities. J. Am. Chem. Soc. 2001, 123, 1556-1563.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 1556-1563
    • Perrin, D.M.1    Garestier, T.2    Hélène, C.3
  • 17
    • 1842618467 scopus 로고    scopus 로고
    • Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities
    • Sidorov, A.V.; Grasby, J.A.; Williams, D.M. Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities. Nucleic Acids Res. 2004, 32, 1591-1601.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1591-1601
    • Sidorov, A.V.1    Grasby, J.A.2    Williams, D.M.3
  • 20
    • 0030963855 scopus 로고    scopus 로고
    • RNA-catalysed carbon-carbon bond formation
    • Tarasow, T.M.; Tarasow, S.L.; Eaton, B.E. RNA-catalysed carbon-carbon bond formation. Nature 1997, 389, 54-57.
    • (1997) Nature , vol.389 , pp. 54-57
    • Tarasow, T.M.1    Tarasow, S.L.2    Eaton, B.E.3
  • 23
    • 0032568617 scopus 로고    scopus 로고
    • Nucleic acid enzymes: Playing with a fuller deck
    • Joyce, G.F. Nucleic acid enzymes: Playing with a fuller deck. Proc. Natl. Acad. Sci. USA 1998, 95, 5845-5847.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5845-5847
    • Joyce, G.F.1
  • 24
    • 0032922298 scopus 로고    scopus 로고
    • Expanding the catalytic repertoire of nucleic acid catalysts: Simultaneous incorporation of two modified deoxyribonucleoside triphosphates bearing ammonium and imidazolyl functionalities
    • Perrin, D.M.; Garestier, T.; Hélène, C. Expanding the catalytic repertoire of nucleic acid catalysts: simultaneous incorporation of two modified deoxyribonucleoside triphosphates bearing ammonium and imidazolyl functionalities. Nucleos. Nucleot. 1999, 18, 377-391.
    • (1999) Nucleos. Nucleot. , vol.18 , pp. 377-391
    • Perrin, D.M.1    Garestier, T.2    Hélène, C.3
  • 26
    • 0037362544 scopus 로고    scopus 로고
    • Combinatorial compound libraries for drug discovery: An ongoing challenge
    • Geysen, H.M.; Schoenen, F.; Wagner, D.; Wagner, R. Combinatorial compound libraries for drug discovery: an ongoing challenge. Nat. Rev. Drug Discov. 2003, 2, 222-230.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 222-230
    • Geysen, H.M.1    Schoenen, F.2    Wagner, D.3    Wagner, R.4
  • 28
    • 0033899547 scopus 로고    scopus 로고
    • Towards the selection of phosphorothioate aptamers optimizing in vitro selection steps with phosphorothioate nucleotides
    • Andreola, M.L.; Calmels, C.; Michel, J.; Toulmé, J.J.; Litvak, S. Towards the selection of phosphorothioate aptamers optimizing in vitro selection steps with phosphorothioate nucleotides. Eur. J. Biochem. 2000, 267, 5032-5040.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 5032-5040
    • Andreola, M.L.1    Calmels, C.2    Michel, J.3    Toulmé, J.J.4    Litvak, S.5
  • 29
    • 0034284164 scopus 로고    scopus 로고
    • Expanding the structural and functional diversity of RNA: Analog uridine triphosphates as candidates for in vitro selection of nucleic acids
    • Vaish, N.K.; Fraley, A.W.; Szostak, J.W.; McLaughlin, L.W. Expanding the structural and functional diversity of RNA: analog uridine triphosphates as candidates for in vitro selection of nucleic acids. Nucleic Acids Res. 2000, 28, 3316-3322.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 3316-3322
    • Vaish, N.K.1    Fraley, A.W.2    Szostak, J.W.3    McLaughlin, L.W.4
  • 30
    • 0035930783 scopus 로고    scopus 로고
    • Expansion of structural and functional diversities of DNA using new 5-substituted deoxyuridine derivatives by PCR with superthermophilic KOD Dash DNA polymerase
    • Sawai, H.; Ozaki, A.N.; Satoh, F.; Ohbayashi, T.; Masud, M.M.; Ozaki, H. Expansion of structural and functional diversities of DNA using new 5-substituted deoxyuridine derivatives by PCR with superthermophilic KOD Dash DNA polymerase. Chem. Commun. 2001, 24, 2604-2605.
    • (2001) Chem. Commun. , vol.24 , pp. 2604-2605
    • Sawai, H.1    Ozaki, A.N.2    Satoh, F.3    Ohbayashi, T.4    Masud, M.M.5    Ozaki, H.6
  • 31
    • 33750993500 scopus 로고    scopus 로고
    • Systematic characterization of 2'-deoxynucleoside- 5'- triphosphate analogs as substrates for DNA polymerases by polymerase chain reaction and kinetic studies on enzymatic production of modified DNA
    • Kuwahara, M.; Nagashima, J.; Hasegawa, M.; Tamura, T.; Kitagata, R.; Hanawa, K.; Hososhima, S.; Kasamatsu, T.; Ozaki, H.; Sawai, H. Systematic characterization of 2'-deoxynucleoside- 5'- triphosphate analogs as substrates for DNA polymerases by polymerase chain reaction and kinetic studies on enzymatic production of modified DNA. Nucleic Acids Res. 2006, 34, 5383-5394.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 5383-5394
    • Kuwahara, M.1    Nagashima, J.2    Hasegawa, M.3    Tamura, T.4    Kitagata, R.5    Hanawa, K.6    Hososhima, S.7    Kasamatsu, T.8    Ozaki, H.9    Sawai, H.10
  • 32
    • 0032476840 scopus 로고    scopus 로고
    • III. Expanding the potential of DNA for binding and catalysis: Highly functionalized dUTP derivatives that are substrates for thermostable DNA polymerases
    • Sakthivel, K.; Barbas, C.F., III. Expanding the potential of DNA for binding and catalysis: highly functionalized dUTP derivatives that are substrates for thermostable DNA polymerases. Angew. Chem. Int. Ed. 1998, 37, 2872-2875.
    • (1998) Angew. Chem. Int. Ed. , vol.37 , pp. 2872-2875
    • Sakthivel, K.1    Barbas, C.F.2
  • 33
    • 0035813885 scopus 로고    scopus 로고
    • Functionalized DNA: A new replicable biopolymer
    • Thum, O.; Jäger, S.; Famulok, M. Functionalized DNA: a new replicable biopolymer. Angew. Chem. Int. Ed. 2001, 40, 3990-3993.
    • (2001) Angew. Chem. Int. Ed. , vol.40 , pp. 3990-3993
    • Thum, O.1    Jäger, S.2    Famulok, M.3
  • 35
    • 0036713391 scopus 로고    scopus 로고
    • Challenging artificial genetic systems: Thymidine analogs with 5- position sulfur functionality
    • Held, H.A.; Benner, S.A. Challenging artificial genetic systems: thymidine analogs with 5- position sulfur functionality. Nucleic Acids Res. 2002, 30, 3857-3869.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 3857-3869
    • Held, H.A.1    Benner, S.A.2
  • 36
    • 0037705455 scopus 로고    scopus 로고
    • Incorporation of reporter molecule-labeled nucleotides by DNA polymerases. II. High-density labeling of natural DNA
    • Tasara, T.; Angerer, B.; Damond, M.; Winter, H.; Dorhofer, S.; Hubscher, U.; Amacker, M. Incorporation of reporter molecule-labeled nucleotides by DNA polymerases. II. High-density labeling of natural DNA. Nucleic Acids Res. 2003, 31, 2636-2646.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 2636-2646
    • Tasara, T.1    Angerer, B.2    Damond, M.3    Winter, H.4    Dorhofer, S.5    Hubscher, U.6    Amacker, M.7
  • 39
    • 34547208319 scopus 로고    scopus 로고
    • An efficient construction of functionalized DNA bearing amino acid groups by cross-coupling reactions of nucleoside triphosphates followed by primer extension or PCR
    • Čapek, P.; Cahová, H.; Pohl, R.; Hocek, M.; Gloeckner, C.; Marx, A. An efficient construction of functionalized DNA bearing amino acid groups by cross-coupling reactions of nucleoside triphosphates followed by primer extension or PCR. Chem. Eur. J. 2007, 13, 6196-6203.
    • (2007) Chem. Eur. J. , vol.13 , pp. 6196-6203
    • Čapek, P.1    Cahová, H.2    Pohl, R.3    Hocek, M.4    Gloeckner, C.5    Marx, A.6
  • 40
    • 37848999066 scopus 로고    scopus 로고
    • Amplification of 4'-thioDNA in the presence of 4'-thio-dTTP and 4'-thio-dCTP, and 4'-thioDNA-directed transcription in vitro and in mammalian cells
    • Inoue, N.; Shionoya, A.; Minakawa, N.; Kawakami, A.; Ogawa, N.; Matsuda, A. Amplification of 4'-thioDNA in the presence of 4'-thio-dTTP and 4'-thio-dCTP, and 4'-thioDNA-directed transcription in vitro and in mammalian cells. J. Am. Chem. Soc. 2007, 129, 15424-15425.
    • (2007) J. Am. Chem. Soc. , vol.129 , pp. 15424-15425
    • Inoue, N.1    Shionoya, A.2    Minakawa, N.3    Kawakami, A.4    Ogawa, N.5    Matsuda, A.6
  • 41
    • 41949124411 scopus 로고    scopus 로고
    • Aminophenyl- and nitrophenyl-labeled nucleoside triphosphates: Synthesis, enzymatic incorporation, and electrochemical detection
    • Cahová, H.; Havran, L.; Brázdilová, P.; Pivonková, H.; Pohl, R.; Fojta, M.; Hocek, M. Aminophenyl- and nitrophenyl-labeled nucleoside triphosphates: synthesis, enzymatic incorporation, and electrochemical detection. Angew. Chem. Int. Ed. Engl. 2008, 47, 2059-2062.
    • (2008) Angew. Chem. Int. Ed. Engl. , vol.47 , pp. 2059-2062
    • Cahová, H.1    Havran, L.2    Brázdilová, P.3    Pivonková, H.4    Pohl, R.5    Fojta, M.6    Hocek, M.7
  • 44
    • 46049121018 scopus 로고    scopus 로고
    • Polymerase chain reaction and transcription using locked nucleic acid nucleotide triphosphates
    • Veedu, R.N.; Vester, B.; Wengel, J. Polymerase chain reaction and transcription using locked nucleic acid nucleotide triphosphates. J. Am. Chem. Soc. 2008, 130, 8124-8125 45.
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 8124-8125
    • Veedu, R.N.1    Vester, B.2    Wengel, J.3
  • 46
    • 65349130574 scopus 로고    scopus 로고
    • Enzymatic synthesis of perfluoroalkylated DNA
    • Holzberger, B.; Marx, A. Enzymatic synthesis of perfluoroalkylated DNA. Bioorg. Med. Chem. 2009, 17, 3653-3658.
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 3653-3658
    • Holzberger, B.1    Marx, A.2
  • 47
    • 62749090570 scopus 로고    scopus 로고
    • Enzymatic incorporation of emissive pyrimidine ribonucleotides
    • Srivatsan, S.G.; Tor, Y. Enzymatic incorporation of emissive pyrimidine ribonucleotides. Chem. Asian J. 2009, 4, 419-427.
    • (2009) Chem. Asian J. , vol.4 , pp. 419-427
    • Srivatsan, S.G.1    Tor, Y.2
  • 48
    • 58449124352 scopus 로고    scopus 로고
    • 2+ complexes: Construction by polymerase incorporation of modified nucleoside triphosphates, electrochemical and luminescent properties, and applications
    • Vrábel, M.; Horáková, P.; Pivonková, H.; Kalachova, L.; Cernocká, H.; Cahová, H.; Pohl, R.; Sebest, P.; Havran, L.; Hocek, M.; Fojta, M. Base-modified DNA labeled by [Ru(bpy)3]2+ and [Os(bpy)3]2+ complexes: construction by polymerase incorporation of modified nucleoside triphosphates, electrochemical and luminescent properties, and applications. Chem. Eur. J. 2009, 15, 1144-1154.
    • (2009) Chem. Eur. J. , vol.15 , pp. 1144-1154
    • Vrábel, M.1    Horáková, P.2    Pivonková, H.3    Kalachova, L.4    Cernocká, H.5    Cahová, H.6    Pohl, R.7    Sebest, P.8    Havran, L.9    Hocek, M.10    Fojta, M.11
  • 49
    • 63249083854 scopus 로고    scopus 로고
    • Diene-modified nucleotides for the Diels-Alder-mediated functional tagging of DNA
    • Borsenberger, V.; Howorka, S. Diene-modified nucleotides for the Diels-Alder-mediated functional tagging of DNA. Nucleic Acids Res. 2009, 37, 1477-1485.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 1477-1485
    • Borsenberger, V.1    Howorka, S.2
  • 50
    • 67649329663 scopus 로고    scopus 로고
    • Efficient enzymatic synthesis of LNA-modified DNA duplexes using KOD DNA polymerase
    • Veedu, R.N.; Vester, B.; Wengel, J. Efficient enzymatic synthesis of LNA-modified DNA duplexes using KOD DNA polymerase. Org. Biomol. Chem. 2009, 7, 1404-1409.
    • (2009) Org. Biomol. Chem. , vol.7 , pp. 1404-1409
    • Veedu, R.N.1    Vester, B.2    Wengel, J.3
  • 51
    • 69549097778 scopus 로고    scopus 로고
    • Synthesis and enzymatic incorporation of modified deoxyuridine triphosphates
    • Borsenberger, V.; Kukwikila, M.; Howorka S. Synthesis and enzymatic incorporation of modified deoxyuridine triphosphates. Org. Biomol. Chem. 2009, 7, 3826-3835.
    • (2009) Org. Biomol. Chem. , vol.7 , pp. 3826-3835
    • Borsenberger, V.1    Kukwikila, M.2    Howorka, S.3
  • 52
    • 76249129616 scopus 로고    scopus 로고
    • Direct polymerase synthesis of reactive aldehydefunctionalized DNA and its conjugation and staining with hydrazines
    • Raindlová, V.; Pohl, R.; Sanda, M.; Hocek, M. Direct polymerase synthesis of reactive aldehydefunctionalized DNA and its conjugation and staining with hydrazines. Angew. Chem. Int. Ed. Engl. 2010, 49, 1064-1066.
    • (2010) Angew. Chem. Int. Ed. Engl. , vol.49 , pp. 1064-1066
    • Raindlová, V.1    Pohl, R.2    Sanda, M.3    Hocek, M.4
  • 53
    • 73949160570 scopus 로고    scopus 로고
    • Enzymatic synthesis of organic-polymer-grafted DNA
    • Baccaro, A.; Marx, A. Enzymatic synthesis of organic-polymer-grafted DNA. Chem. Eur. J. 2010, 16, 218-226.
    • (2010) Chem. Eur. J. , vol.16 , pp. 218-226
    • Baccaro, A.1    Marx, A.2
  • 54
    • 77953584996 scopus 로고    scopus 로고
    • High-density DNA functionalization by a combination of Cucatalyzed and Cu-free click chemistry
    • Gutsmiedl, K.; Fazio, D.; Carell, T. High-density DNA functionalization by a combination of Cucatalyzed and Cu-free click chemistry. Chem. Eur. J. 2010, 16, 6877-6883.
    • (2010) Chem. Eur. J. , vol.16 , pp. 6877-6883
    • Gutsmiedl, K.1    Fazio, D.2    Carell, T.3
  • 55
    • 77950813096 scopus 로고    scopus 로고
    • CyDNA: Synthesis and replication of highly Cy-dye substituted DNA by an evolved polymerase
    • Ramsay, N.; Jemth, A.S.; Brown, A.; Crampton, N.; Dear, P.; Holliger, P. CyDNA: synthesis and replication of highly Cy-dye substituted DNA by an evolved polymerase. J. Am. Chem. Soc. 2010, 132, 5096-5104.
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 5096-5104
    • Ramsay, N.1    Jemth, A.S.2    Brown, A.3    Crampton, N.4    Dear, P.5    Holliger, P.6
  • 56
    • 77149150613 scopus 로고    scopus 로고
    • Synthesis of nucleoside and nucleotide conjugates of bile acids, and polymerase construction of bile acid-functionalized DNA
    • Ikonen, S.; Macícková-Cahová, H.; Pohl, R.; Sanda, M.; Hocek, M. Synthesis of nucleoside and nucleotide conjugates of bile acids, and polymerase construction of bile acid-functionalized DNA. Org. Biomol. Chem. 2010, 8, 1194-1201.
    • (2010) Org. Biomol. Chem. , vol.8 , pp. 1194-1201
    • Ikonen, S.1    MacÍcková-Cahová, H.2    Pohl, R.3    Sanda, M.4    Hocek, M.5
  • 57
    • 0028641549 scopus 로고
    • Modified RNA sequence pools for in vitro selection
    • Lin, Y.; Qiu, Q.; Gill, S.C.; Jayasena, S.D. Modified RNA sequence pools for in vitro selection. Nucleic Acids Res. 1994, 22, 5229-5234.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5229-5234
    • Lin, Y.1    Qiu, Q.2    Gill, S.C.3    Jayasena, S.D.4
  • 59
  • 62
    • 0029557118 scopus 로고
    • Using in vitro selection to direct the covalent attachment of HIV-1 Rev protein to high affinity RNA ligands
    • Jensen, K.B.; Atkinson, B.L.; Willis, M.C.; Koch, T.H.; Gold, L. Using in vitro selection to direct the covalent attachment of HIV-1 Rev protein to high affinity RNA ligands. Proc. Natl. Acad. Sci. USA 1995, 92, 12220-12224.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12220-12224
    • Jensen, K.B.1    Atkinson, B.L.2    Willis, M.C.3    Koch, T.H.4    Gold, L.5
  • 65
    • 0028136665 scopus 로고
    • The application of a modified nucleotide in aptamer selection: Novel thrombin aptamers containing-(1-pentynyl)-2'-deoxyuridine
    • Latham, J.A.; Johnson, R.; Toole, J.J. The application of a modified nucleotide in aptamer selection: novel thrombin aptamers containing-(1-pentynyl) -2'-deoxyuridine. Nucleic Acids Res. 1994, 22, 2817-2822.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 2817-2822
    • Latham, J.A.1    Johnson, R.2    Toole, J.J.3
  • 67
    • 0033610480 scopus 로고    scopus 로고
    • Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analog
    • Battersby, T.R.; Ang, D.N.; Burgstaller, P.; Jurczyk, S.C.; Bowser, M.T.; Buchanan, D.D.; Kennedy R.T.; Benner, S.A. Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analog. J. Am. Chem. Soc. 1999, 121, 9781-9789.
    • (1999) J. Am. Chem. Soc. , vol.121 , pp. 9781-9789
    • Battersby, T.R.1    Ang, D.N.2    Burgstaller, P.3    Jurczyk, S.C.4    Bowser, M.T.5    Buchanan, D.D.6    Kennedy, R.T.7    Benner, S.A.8
  • 68
    • 0027180473 scopus 로고
    • An RNA motif that binds ATP
    • Sassanfar, M.; Szostak, J.W. An RNA motif that binds ATP. Nature 1993, 364, 550-553.
    • (1993) Nature , vol.364 , pp. 550-553
    • Sassanfar, M.1    Szostak, J.W.2
  • 69
    • 0028965943 scopus 로고
    • DNA aptamer that binds adenosine and ATP
    • Huizenga, D.E.; Szostak, J.W. DNA Aptamer that Binds Adenosine and ATP. Biochemistry 1995, 34, 656-665.
    • (1995) Biochemistry , vol.34 , pp. 656-665
    • Huizenga, D.E.1    Szostak, J.W.2
  • 70
    • 33846799193 scopus 로고    scopus 로고
    • Modified DNA aptamer that binds the (R)-isomer of a thalidomide derivative with high enantioselectivity
    • Shoji, A.; Kuwahara, M.; Ozaki, H.; Sawai, H. Modified DNA aptamer that binds the (R)-isomer of a thalidomide derivative with high enantioselectivity. J. Am. Chem. Soc. 2007,129, 1456-1464.
    • (2007) J. Am. Chem. Soc. , vol.129 , pp. 1456-1464
    • Shoji, A.1    Kuwahara, M.2    Ozaki, H.3    Sawai, H.4
  • 76
    • 0032493654 scopus 로고    scopus 로고
    • 2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
    • Ruckman, J.; Green, L.S.; Beeson, J.; Waugh, S.; Gillette, W.L.; Henninger, D.D.; Claesson-Welsh, L.; Janjić, N. 2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain. J. Biol. Chem. 1998, 273, 20556-20567.
    • (1998) J. Biol. Chem. , vol.273 , pp. 20556-20567
    • Ruckman, J.1    Green, L.S.2    Beeson, J.3    Waugh, S.4    Gillette, W.L.5    Henninger, D.D.6    Claesson-Welsh, L.7    Janjić, N.8
  • 77
    • 0015216137 scopus 로고
    • Estimation of secondary structure in ribonucleic acids
    • Tinoco, I., Jr; Uhlenbeck, O.C.; Levine, M.D. Estimation of secondary structure in ribonucleic acids. Nature 1971, 230, 362-367.
    • (1971) Nature , vol.230 , pp. 362-367
    • Tinoco Jr., I.1    Uhlenbeck, O.C.2    Levine, M.D.3
  • 78
    • 28444496049 scopus 로고    scopus 로고
    • Central dogma for a molecular design based on DNA: DNB (databasing/designable nanobio) → ENB (engineering nanobio) → FNB (functional nanobio)
    • Nakano, S.; Sugimoto, N. Central dogma for a molecular design based on DNA: DNB (databasing/designable nanobio) → ENB (engineering nanobio) → FNB (functional nanobio). Chem. Lett. 2005, 34, 1206-1211.
    • (2005) Chem. Lett. , vol.34 , pp. 1206-1211
    • Nakano, S.1    Sugimoto, N.2
  • 79
    • 58349085733 scopus 로고    scopus 로고
    • Designable DNA Functions toward New Nanobiotechnology
    • Sugimoto, N. Designable DNA Functions toward New Nanobiotechnology. Bull. Chem. Soc. Jpn. 2009, 82, 1-10.
    • (2009) Bull. Chem. Soc. Jpn. , vol.82 , pp. 1-10
    • Sugimoto, N.1
  • 82
    • 22444448397 scopus 로고    scopus 로고
    • Investigation of the DNA-dependent cyclohexenyl nucleic acid polymerization and the cyclohexenyl nucleic acid-dependent DNA polymerization
    • Kempeneers, V.; Renders, M.; Froeyen, M.; Herdewijn, P. Investigation of the DNA-dependent cyclohexenyl nucleic acid polymerization and the cyclohexenyl nucleic acid-dependent DNA polymerization. Nucleic Acids Res. 2005, 33, 3828-3836.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 3828-3836
    • Kempeneers, V.1    Renders, M.2    Froeyen, M.3    Herdewijn, P.4
  • 84
    • 33750204643 scopus 로고    scopus 로고
    • Dynamic assembly of primers on nucleic acid templates
    • Leal, N.A.; Sukeda, M.; Benner, S.A. Dynamic assembly of primers on nucleic acid templates. Nucleic Acids Res. 2006, 34, 4702-4710.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 4702-4710
    • Leal, N.A.1    Sukeda, M.2    Benner, S.A.3
  • 85
    • 35548977605 scopus 로고    scopus 로고
    • Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template
    • Tsai, C.H.; Chen, J., Szostak, J.W. Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template. Proc. Natl. Acad. Sci. USA 2007, 104, 14598-14603.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 14598-14603
    • Tsai, C.H.1    Chen, J.2    Szostak, J.W.3
  • 86
    • 48349115007 scopus 로고    scopus 로고
    • Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2',4'-bridged nucleosides
    • Kuwahara, M.; Obika, S.; Nagashima, J.; Ohta, Y.; Suto, Y.; Ozaki, H.; Sawai, H.; Imanishi, T. Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2',4'-bridged nucleosides. Nucleic Acids Res. 2008, 36, 4257-4265.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 4257-4265
    • Kuwahara, M.1    Obika, S.2    Nagashima, J.3    Ohta, Y.4    Suto, Y.5    Ozaki, H.6    Sawai, H.7    Imanishi, T.8
  • 87
    • 84920506277 scopus 로고    scopus 로고
    • Transcription and reverse transcription of artificial nucleic acids involving backbone modification by templatedirected DNA polymerase reactions
    • Kuwahara, M.; Takeshima, H.; Nagashima, J.; Minezaki, S.; Ozaki, H.; Sawai, H. Transcription and reverse transcription of artificial nucleic acids involving backbone modification by templatedirected DNA polymerase reactions. Bioorg. Med. Chem. 2009, 17, 3782-3788.
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 3782-3788
    • Kuwahara, M.1    Takeshima, H.2    Nagashima, J.3    Minezaki, S.4    Ozaki, H.5    Sawai, H.6
  • 88
    • 67849124661 scopus 로고    scopus 로고
    • Synthesis and polymerase chain reaction amplification of DNA strands containing an unnatural triazole linkage
    • El-Sagheer, A.H.; Brown, T. Synthesis and polymerase chain reaction amplification of DNA strands containing an unnatural triazole linkage. J. Am. Chem. Soc. 2009, 131, 3958-3964.
    • (2009) J. Am. Chem. Soc. , vol.131 , pp. 3958-3964
    • El-Sagheer, A.H.1    Brown, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.