Synergistic effect of aptamers that inhibit exosites 1 and 2 on thrombin

RNA

Volumn 15, Issue 12, 2009, Pages 2105-2111

  Nimjee, Shahid M ^a   Oney, Sabah ^a   Volovyk, Zoya ^a   Bompiani, Kristin M ^a   Long, Steve B ^b   Hoffman, Maureane ^a   Sullenger, Bruce A ^a,c  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NEW YORK STRUCTURAL BIOLOGY CENTER   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aptamer; Coagulation; Exosite 1; Exosite 2; Platelet activation; Thrombin

Indexed keywords

APTAMER; PROCOAGULANT; RNA; THROMBIN;

ANTICOAGULATION; ARTICLE; CONTROLLED STUDY; EXOSITE 1; EXOSITE 2; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RNA STRUCTURE; THROMBOCYTE ACTIVATION;

APTAMERS, NUCLEOTIDE; DRUG SYNERGISM; ENZYME ACTIVATION; FIBRINOLYTIC AGENTS; HUMANS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; P-SELECTIN; PLATELET ACTIVATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; THROMBIN;

EID: 73249126308     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.1240109     Document Type: Article

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