-
1
-
-
50849110204
-
Aptamers in oncology: A diagnostic perspective
-
Khan H, Missailidis S. Aptamers in oncology: a diagnostic perspective. Gene Ther Mol Biol 2008;12:111-128
-
(2008)
Gene Ther Mol Biol
, vol.12
, pp. 111-128
-
-
Khan, H.1
Missailidis, S.2
-
2
-
-
84904915736
-
Aptamers as Anticancer Agents
-
Missailidis S, editor, Wiley & Sons Ltd, UK
-
Makwana V, Simmons S, Missailidis S. "Aptamers as Anticancer Agents". In: Missailidis S, editor, Anticancer Therapeutics, Wiley & Sons Ltd, UK
-
Anticancer Therapeutics
-
-
Makwana, V.1
Simmons, S.2
Missailidis, S.3
-
3
-
-
68249090946
-
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
-
US6051698
-
Janjic N, Gold L, Schmidt P, Vargeese C. Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes. US6051698; 1997
-
(1997)
-
-
Janjic, N.1
Gold, L.2
Schmidt, P.3
Vargeese, C.4
-
4
-
-
33746910190
-
Pegaptanib for the treatment of age-related macular degeneration
-
DOI 10.1016/j.exer.2006.02.010, PII S0014483506001837
-
Zhou B, Wang B. Pegaptanib for the treatment of age-related macular degeneration. Exp Eye Res 2006;83:615-619 (Pubitemid 44183805)
-
(2006)
Experimental Eye Research
, vol.83
, Issue.3
, pp. 615-619
-
-
Zhou, B.1
Wang, B.2
-
5
-
-
29644444716
-
Changes in retinal neovascularization after pegaptanib (Macugen) therapy in diabetic individuals
-
DOI 10.1016/j.ophtha.2005.10.012, PII S0161642005011863
-
Adamis AP, Altaweel M, Bressler NM, et al. Changes in retinal neovascularization after pegaptanib (Macugen) therapy in diabetic individuals. Ophthalmology 2006;113(1):23-28 (Pubitemid 43021723)
-
(2006)
Ophthalmology
, vol.113
, Issue.1
, pp. 23-28
-
-
Bressler, N.M.1
Altaweel, M.2
-
6
-
-
33646948521
-
Pegaptanib sodium for neovascular age-related macular degeneration: Two-year safety results of the two prospective, multicenter, controlled clinical trials
-
D'Amico DJ, Masonson HN, Patel M, et al. Pegaptanib sodium for neovascular age-related macular degeneration: two-year safety results of the two prospective, multicenter, controlled clinical trials. Ophthalmology 2006;113:992-1001
-
(2006)
Ophthalmology
, vol.113
, pp. 992-1001
-
-
D'Amico, D.J.1
Masonson, H.N.2
Patel, M.3
-
7
-
-
0025074907
-
In vitro selection of RNA molecules that bind specific ligands
-
DOI 10.1038/346818a0
-
Ellington AD, Szostak JW. In vitro selection of RNA molecules that bind specific ligands. Nature 1990;346:818-822 (Pubitemid 20272100)
-
(1990)
Nature
, vol.346
, Issue.6287
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
8
-
-
0025194307
-
Systemic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
-
Tuerk C, Gold L. Systematic evolution of ligands by exponential enrichment - RNA ligands to bacteriophage-T4 DNA-polymerase. Science 1990;249:505-510 (Pubitemid 20248891)
-
(1990)
Science
, vol.249
, Issue.4968
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
9
-
-
68249121202
-
Nucleic acid ligands
-
US5475096
-
Gold L, Tuerk C. Nucleic acid ligands. US5475096; 1995
-
(1995)
-
-
Gold, L.1
Tuerk, C.2
-
10
-
-
13244264560
-
Methods for identifying nucleic acid ligands
-
US5270163
-
Gold L, Tuerk C. Methods for identifying nucleic acid ligands. US5270163; 1993
-
(1993)
-
-
Gold, L.1
Tuerk, C.2
-
11
-
-
68249121202
-
Nucleic acid ligands
-
US5670637
-
Gold L, Tuerk C. Nucleic acid ligands. US5670637; 1997
-
(1997)
-
-
Gold, L.1
Tuerk, C.2
-
12
-
-
68249121202
-
Nucleic acid ligands
-
US5696249
-
Gold L, Tuerk C. Nucleic acid ligands. US5696249; 1997
-
(1997)
-
-
Gold, L.1
Tuerk, C.2
-
13
-
-
68249121202
-
Nucleic acid ligands
-
US5843653
-
Gold L, Tuerk C. Nucleic acid ligands. US5843653; 1998
-
(1998)
-
-
Gold, L.1
Tuerk, C.2
-
14
-
-
68249132690
-
Nucleic acid ligands
-
US6110900
-
Gold L, Tuerk C. Nucleic acid ligands. US6110900; 2000
-
(2000)
-
-
Gold, L.1
Tuerk, C.2
-
15
-
-
4243859321
-
High-affinity nucleic acid ligands that discriminate between tehophylline and caffeine
-
US5580737
-
Polisky B, Jenison RD, Gold L. High-affinity nucleic acid ligands that discriminate between tehophylline and caffeine. US5580737; 1996
-
(1996)
-
-
Polisky, B.1
Jenison, R.D.2
Gold, L.3
-
18
-
-
68249106441
-
Systematic evolution of ligands by exponential enrichment: Blended SELEX
-
US5683867
-
Biesecker G, Jayasena SD, Gold L, et al. Systematic evolution of ligands by exponential enrichment: blended SELEX. US5683867; 1997
-
(1997)
-
-
Biesecker, G.1
Jayasena, S.D.2
Gold, L.3
-
19
-
-
0344818672
-
Transcription-free SELEX
-
US6387620
-
Smith JD, Gold L. Transcription-free SELEX. US6387620; 2002
-
(2002)
-
-
Smith, J.D.1
Gold, L.2
-
20
-
-
68249088320
-
Systematic evolution of ligands by exponential enrichment: Solution SELEX
-
US5567588
-
Gold L, Rinqquist S. Systematic evolution of ligands by exponential enrichment: solution SELEX. US5567588; 1996
-
(1996)
-
-
Gold, L.1
Rinqquist, S.2
-
21
-
-
68249107505
-
Systematic evolution of ligands by exponential enrichment: Chimeric SELEX
-
WO199604403
-
Burke D, Tarasow T, Eaton B, Gold L. Systematic evolution of ligands by exponential enrichment: chimeric SELEX. WO199604403; 1996
-
(1996)
-
-
Burke, D.1
Tarasow, T.2
Eaton, B.3
Gold, L.4
-
22
-
-
68249094791
-
Systematic evolution of ligands by exponential enrichment: Tissue SELEX
-
US6376474
-
Heiliq JS, Gold L. Systematic evolution of ligands by exponential enrichment: tissue SELEX. US6376474; 2002
-
(2002)
-
-
Heiliq, J.S.1
Gold, L.2
-
23
-
-
68249102481
-
Systematic evolution of ligands by exponential enrichment: Photoselection of nucleic acid ligands and solution SELEX
-
US6001577
-
Gold L, Willis M, Koch T, et al. Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution SELEX. US6001577; 1999
-
(1999)
-
-
Gold, L.1
Willis, M.2
Koch, T.3
-
24
-
-
68249127792
-
RNA aptamers and methods for identifying the same
-
US7312325
-
Sullenger BA, Rusconi CP. RNA aptamers and methods for identifying the same. US7312325; 2007
-
(2007)
-
-
Sullenger, B.A.1
Rusconi, C.P.2
-
25
-
-
68249124449
-
Systematic evolution of ligands by exponential enrichment: Chemi-SELEX
-
US5763595
-
Gold L, Eaton B, Smith D, et al. Systematic evolution of ligands by exponential enrichment: chemi-SELEX. US5763595; 1998
-
(1998)
-
-
Gold, L.1
Eaton, B.2
Smith, D.3
-
27
-
-
0345681450
-
Modified SELEX processes without purified protein
-
WO2002024954
-
Gold L, Zichi DA, Smith JD. Modified SELEX processes without purified protein. WO2002024954; 2002
-
(2002)
-
-
Gold, L.1
Zichi, D.A.2
Smith, J.D.3
-
28
-
-
68249091494
-
In vitro evaluation of nucleic acid ligands
-
WO2003102212
-
Bowser M, Mendonsa S. In vitro evaluation of nucleic acid ligands. WO2003102212; 2003
-
(2003)
-
-
Bowser, M.1
Mendonsa, S.2
-
29
-
-
68249120677
-
Selection of aptamers based on geometry
-
20080182759
-
West JAA, Satterfield BC. Selection of aptamers based on geometry. 20080182759; 2008
-
(2008)
-
-
West, J.A.A.1
Satterfield, B.C.2
-
30
-
-
68249084936
-
Mirror-symmetrical selection and evolution of nucleic acids
-
WO1998008856
-
Furste JP, Bald R, Erdmann VA. Mirror-symmetrical selection and evolution of nucleic acids. WO1998008856; 1998
-
(1998)
-
-
Furste, J.P.1
Bald, R.2
Erdmann, V.A.3
-
31
-
-
68249121201
-
Method and apparatus for designing a nucleic acid having a desired property
-
EP1386972
-
Kleinjung F, Roehl I, Wientges J. Method and apparatus for designing a nucleic acid having a desired property. EP1386972; 2004
-
(2004)
-
-
Kleinjung, F.1
Roehl, I.2
Wientges, J.3
-
32
-
-
68249121991
-
Focused libraries, functional profiling, laser SELEX and DESELEX
-
WO2007035532
-
Sullenger BA, Layzer JM, Rusconi CP, et al. Focused libraries, functional profiling, laser SELEX and DESELEX. WO2007035532; 2007
-
(2007)
-
-
Sullenger, B.A.1
Layzer, J.M.2
Rusconi, C.P.3
-
33
-
-
4243795411
-
High affinity nucleic acid ligands containing modified nucleotides
-
US5660985
-
Pieken W, Tasset D, Janjic N, et al. High affinity nucleic acid ligands containing modified nucleotides. US5660985; 1997
-
(1997)
-
-
Pieken, W.1
Tasset, D.2
Janjic, N.3
-
34
-
-
68249126067
-
Aptamers comprising arabinose modified nucleotides
-
WO2007038869
-
Damha M, Peng CG. Aptamers comprising arabinose modified nucleotides. WO2007038869; 2007
-
(2007)
-
-
Damha, M.1
Peng, C.G.2
-
35
-
-
68249130084
-
Extending the lifetime of anticoagulant oligodeoxynucleotide aptamers in blood
-
US6780850
-
Dougan AH, Weitz JI. Extending the lifetime of anticoagulant oligodeoxynucleotide aptamers in blood. US6780850; 2004
-
(2004)
-
-
Dougan, A.H.1
Weitz, J.I.2
-
36
-
-
68249107506
-
Oligomers that bind to KU protein
-
WO1999033971
-
Dynan W, Yoo S. Oligomers that bind to KU protein. WO1999033971; 1999
-
(1999)
-
-
Dynan, W.1
Yoo, S.2
-
37
-
-
68249116177
-
Bi-directional oligonucleotides that bind thrombin
-
US5668265
-
Nadeau JG, Ciolkowski ML, Vogler EA. Bi-directional oligonucleotides that bind thrombin. US5668265; 1997
-
(1997)
-
-
Nadeau, J.G.1
Ciolkowski, M.L.2
Vogler, E.A.3
-
38
-
-
68249114143
-
Multivalent aptamer therapeutics with improved pharmacodynamic properties and methods of making and using the same
-
WO2004047742
-
Wilson C, Epstein D, Kurz J. Multivalent aptamer therapeutics with improved pharmacodynamic properties and methods of making and using the same. WO2004047742; 2004
-
(2004)
-
-
Wilson, C.1
Epstein, D.2
Kurz, J.3
-
39
-
-
66749106259
-
Technical and biological issues relevant to cell typing with aptamers
-
Li N, Ebright JN, Stovall GM, et al. Technical and biological issues relevant to cell typing with aptamers. J Proteome Res 2009;8:2438-2448
-
(2009)
J Proteome Res
, vol.8
, pp. 2438-2448
-
-
Li, N.1
Ebright, J.N.2
Stovall, G.M.3
-
40
-
-
68249117318
-
Aptamer-based radiopharmaceuticals for diagnostic imaging and targeted radiotherapy of epithelial tumors
-
Missailidis S, Perkins A, David Santos-Filho S, et al. Aptamer-based radiopharmaceuticals for diagnostic imaging and targeted radiotherapy of epithelial tumors. Braz Arch Biol Technol 2008;51:77-83
-
(2008)
Braz Arch Biol Technol
, vol.51
, pp. 77-83
-
-
Missailidis, S.1
Perkins, A.2
David Santos-Filho, S.3
-
41
-
-
68249106191
-
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
-
US6051698
-
Janjic N, Gold L, Schmidt P, Vargeese C. Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes. US6051698; 2000
-
(2000)
-
-
Janjic, N.1
Gold, L.2
Schmidt, P.3
Vargeese, C.4
-
42
-
-
68249132405
-
-
Available from
-
Available from: www.ClinicalTrials.gov
-
-
-
-
43
-
-
68249096900
-
High affinity PDGF nucleic acid ligands
-
US5668264
-
Janjic N, Gold L. High affinity PDGF nucleic acid ligands. US5668264; 1997
-
(1997)
-
-
Janjic, N.1
Gold, L.2
-
44
-
-
68249123306
-
Method for treatment of tumors using nucleic acid ligands to PDGF
-
US6699843
-
Pietras K, Ostman A, Heldin C-H, Rubin K. Method for treatment of tumors using nucleic acid ligands to PDGF. US6699843; 2004
-
(2004)
-
-
Pietras, K.1
Ostman, A.2
Heldin, C.-H.3
Rubin, K.4
-
45
-
-
0035297541
-
Ihibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors
-
Pietras K, Ostman A, Sjoquist M. Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors. Cancer Res 2001;61:2929-2934 (Pubitemid 32691937)
-
(2001)
Cancer Research
, vol.61
, Issue.7
, pp. 2929-2934
-
-
Pietras, K.1
Ostman, A.2
Sjoquist, M.3
Buchdunger, E.4
Reed, R.K.5
Heldin, C.-H.6
Rubin, K.7
-
46
-
-
0036790060
-
Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy
-
Pietras K, Rubin K, Sjoblom T. Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy. Cancer Res 2002;62:5476-5484
-
(2002)
Cancer Res
, vol.62
, pp. 5476-5484
-
-
Pietras, K.1
Rubin, K.2
Sjoblom, T.3
-
47
-
-
33744728068
-
Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization
-
DOI 10.2353/ajpath.2006.050588
-
Jo N, Mailhos C, Ju M, et al. Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization. Am J Pathol 2006;168:2036-2053 (Pubitemid 43825322)
-
(2006)
American Journal of Pathology
, vol.168
, Issue.6
, pp. 2036-2053
-
-
Jo, N.1
Mailhos, C.2
Ju, M.3
Cheung, E.4
Bradley, J.5
Nishijima, K.6
Robinson, G.S.7
Adamis, A.P.8
Shima, D.T.9
-
48
-
-
68249093488
-
Complement binding aptamers and anti-C5 agents useful in the treatment of ocular disorders
-
WO2007103549
-
Epstein D, Kurz J. Complement binding aptamers and anti-C5 agents useful in the treatment of ocular disorders. WO2007103549; 2007
-
(2007)
-
-
Epstein, D.1
Kurz, J.2
-
50
-
-
68249092984
-
High-affinity ligands of basic fibroblast growth factor and thrombin
-
WO1995021853
-
Janjic N, Gold L, Tasset D. High-affinity ligands of basic fibroblast growth factor and thrombin. WO1995021853; 1995
-
(1995)
-
-
Janjic, N.1
Gold, L.2
Tasset, D.3
-
52
-
-
68249096899
-
High affinity TGFβ nucleic acid ligands and inhibitors
-
US6124449
-
Gold L, Pagratis N. High affinity TGFβ nucleic acid ligands and inhibitors. US6124449; 2000
-
(2000)
-
-
Gold, L.1
Pagratis, N.2
-
53
-
-
68249120675
-
High affinity HKGF nucleic acid ligands and inhibitors
-
US5846713
-
Pagratis N, Gold L. High affinity HKGF nucleic acid ligands and inhibitors. US5846713; 1998
-
(1998)
-
-
Pagratis, N.1
Gold, L.2
-
54
-
-
68249110837
-
Nucleic acid ligands to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met and to integrins
-
WO2001009159
-
Ruckman J, Gold L, Stephens A, et al. Nucleic acid ligands to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met and to integrins. WO2001009159; 2001
-
(2001)
-
-
Ruckman, J.1
Gold, L.2
Stephens, A.3
-
55
-
-
0345681444
-
Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met
-
US20030049644
-
Rabin R, Lochrie M, Janjic N, Gold L. Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met. US20030049644; 2003
-
(2003)
-
-
Rabin, R.1
Lochrie, M.2
Janjic, N.3
Gold, L.4
-
56
-
-
68249115437
-
A method for the treatment of malignant diseases by inhitibing nucleolin
-
WO2005035579
-
Bates P, Miller DM, Trent JO, Xiaohua X. A method for the treatment of malignant diseases by inhitibing nucleolin. WO2005035579; 2005
-
(2005)
-
-
Bates, P.1
Miller, D.M.2
Trent, J.O.3
Xiaohua, X.4
-
57
-
-
68249096640
-
Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin
-
US20080318887; US20080318888; US20080318889; US20080318890
-
Trent J, Bates PJ, Miller DM. Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin. US20080318887; US20080318888; US20080318889; US20080318890; 2008
-
(2008)
-
-
Trent, J.1
Bates, P.J.2
Miller, D.M.3
-
58
-
-
0033543548
-
Antiproliferative activity of G-rich oligonucleotides correlates with protein binding
-
Bates PJ, Kahlon JB, Thomas SD, et al. Antiproliferative activity of G-rich oligonucleotides correlates with protein binding. J Biol Chem 1999;274:26369-26377 (Pubitemid 129520069)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.37
, pp. 26369-26377
-
-
Bates, P.J.1
Kahlon, J.B.2
Thomas, S.D.3
Trent, J.O.4
Miller, D.M.5
-
59
-
-
0035900673
-
Inhibition of DNA Replication and Induction of S Phase Cell Cycle Arrest by G-rich Oligonucleotides
-
DOI 10.1074/jbc.M104446200
-
Xu XH, Hamhouvia F, Thomas SD, et al. Inhibition of DNA replication and induction of S phase cell cycle arrest by G-rich oligonucleotides. J Biol Chem 2001;276:43221-43230 (Pubitemid 37371008)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.46
, pp. 43221-43230
-
-
Xu, X.1
Hamhouyia, F.2
Thomas, S.D.3
Burke, T.J.4
Girvan, A.C.5
McGregor, W.G.6
Trent, J.O.7
Miller, D.M.8
Bates, P.J.9
-
60
-
-
33846252731
-
Discovery and development of anticancer aptamers
-
Ireson CR, Kelland LR. Discovery and development of anticancer aptamers. Mol Cancer Ther 2006;5:2957-2962
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2957-2962
-
-
Ireson, C.R.1
Kelland, L.R.2
-
62
-
-
68249088571
-
Aptamers labelled with Gallium-68
-
WO2008028534
-
Friebe M, Hecht M, Dinkelborg L, et al. Aptamers labelled with Gallium-68. WO2008028534; 2008
-
(2008)
-
-
Friebe, M.1
Hecht, M.2
Dinkelborg, L.3
-
63
-
-
68249112506
-
Nucleic acid ligands to the prostate specific membrane antigen
-
US6933114
-
Lupold SE, Lin Y, Hicke BJ, Coffey DS. Nucleic acid ligands to the prostate specific membrane antigen. US6933114; 2005
-
(2005)
-
-
Lupold, S.E.1
Lin, Y.2
Hicke, B.J.3
Coffey, D.S.4
-
65
-
-
68249087796
-
Nucleic acid capable of binding specifically to Ras target protein
-
US6995249
-
Yokoyama S, Hirao I, Sakamoto K. Nucleic acid capable of binding specifically to Ras target protein. US6995249; 2006
-
(2006)
-
-
Yokoyama, S.1
Hirao, I.2
Sakamoto, K.3
-
66
-
-
68249083896
-
Therapeutic use of CIS-element decoys in vivo
-
US6774118
-
Dzau VJ, Gibbons GH, Morishita R. Therapeutic use of CIS-element decoys in vivo. US6774118; 2004
-
(2004)
-
-
Dzau, V.J.1
Gibbons, G.H.2
Morishita, R.3
-
68
-
-
68249113858
-
Nucleic acid ligand inhibitors of human neutrophil elastase
-
US5734034
-
Jayasena SD, Gold L. Nucleic acid ligand inhibitors of human neutrophil elastase. US5734034; 1998
-
(1998)
-
-
Jayasena, S.D.1
Gold, L.2
-
69
-
-
0030889231
-
Highly potent irreversible inhibitors of neutrophil elastase generated by selection from a randomized DNA-valine phosphonate library
-
DOI 10.1021/bi962669h
-
Charlton J, Kirschenheuter GP, Smith D. Highly potent irreversible inhibitors of neutrophil elastase generated by selection from a randomized DNA-valine phosphonate library. Biochemistry 1997;36:3018-3026 (Pubitemid 27138587)
-
(1997)
Biochemistry
, vol.36
, Issue.10
, pp. 3018-3026
-
-
Charlton, J.1
Kirschenheuter, G.P.2
Smith, D.3
-
70
-
-
0029395440
-
In vitro selection of RNA-based irreversible inhibitors of human neutrophil elastase
-
Smith D, Kirschenheuter GP, Charlton J, et al. In vitro selection of RNA-based irreversible inhibitors of human neutrophil elastase. Chem Biol 1995;2:741-750
-
(1995)
Chem Biol
, vol.2
, pp. 741-750
-
-
Smith, D.1
Kirschenheuter, G.P.2
Charlton, J.3
-
71
-
-
0031279943
-
In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase
-
Charlton J, Sennello J, Smith D. In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase. Chem Biol 1997;4:809-816
-
(1997)
Chem Biol
, vol.4
, pp. 809-816
-
-
Charlton, J.1
Sennello, J.2
Smith, D.3
-
72
-
-
68249127251
-
High-affinity oligonucleotide ligands to secretory phospholipase A2(SPLA2)
-
WO1996027604
-
Gold L, Parma D, Janjic N, Lochrie M. High-affinity oligonucleotide ligands to secretory phospholipase A2(SPLA2). WO1996027604; 1996
-
(1996)
-
-
Gold, L.1
Parma, D.2
Janjic, N.3
Lochrie, M.4
-
74
-
-
68249086247
-
MCP-I binding nucleic acids
-
WO2007093409
-
Purschke W, Jarosch F, Eulberg D, et al. MCP-I binding nucleic acids. WO2007093409; 2007
-
(2007)
-
-
Purschke, W.1
Jarosch, F.2
Eulberg, D.3
-
75
-
-
68249120934
-
SDF-I binding nucleic acids
-
WO2008009437
-
Purschke W, Jarosch F, Eulberg D, et al. SDF-I binding nucleic acids. WO2008009437; 2008
-
(2008)
-
-
Purschke, W.1
Jarosch, F.2
Eulberg, D.3
-
76
-
-
68249118097
-
Thio-modified aptamer synthetic methods and compositions
-
WO2000024404
-
Gorenstein DG, Aronson J, Luxon B, Herzog N. Thio-modified aptamer synthetic methods and compositions. WO2000024404; 2000
-
(2000)
-
-
Gorenstein, D.G.1
Aronson, J.2
Luxon, B.3
Herzog, N.4
-
77
-
-
68249088570
-
Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
-
WO2007035922
-
Diener JL, Epstein D, Ferguson A, et al. Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics. WO2007035922; 2007
-
(2007)
-
-
Diener, J.L.1
Epstein, D.2
Ferguson, A.3
-
78
-
-
68249111277
-
High affinity HIV-1 gag nucleic acid ligands
-
US5726017
-
Lochrie MA, Gold L. High affinity HIV-1 gag nucleic acid ligands. US5726017; 1998
-
(1998)
-
-
Lochrie, M.A.1
Gold, L.2
-
79
-
-
68249083405
-
Nucleic acid ligands to HIV-RT and HIV-1 rev
-
US5496938
-
Gold L, Tuerk C. Nucleic acid ligands to HIV-RT and HIV-1 rev. US5496938; 1996
-
(1996)
-
-
Gold, L.1
Tuerk, C.2
-
80
-
-
1642610326
-
Method for identification of high affinity DNA ligands of HIV-1 reverse transcriptase
-
US5503978
-
Schneider DJ, Gold L, Feigon J. Method for identification of high affinity DNA ligands of HIV-1 reverse transcriptase. US5503978; 1996
-
(1996)
-
-
Schneider, D.J.1
Gold, L.2
Feigon, J.3
-
81
-
-
68249116416
-
High affinity HIV nucleocapsid nucleic acid ligands
-
US5654151
-
Allen PN, Gold L. High affinity HIV nucleocapsid nucleic acid ligands. US5654151; 1997
-
(1997)
-
-
Allen, P.N.1
Gold, L.2
-
82
-
-
68249095316
-
High affinity nucleic acid ligands to HIV integrase
-
US5587468
-
Allen P, Gold L. High affinity nucleic acid ligands to HIV integrase. US5587468; 1996
-
(1996)
-
-
Allen, P.1
Gold, L.2
-
83
-
-
68249083895
-
Ligands of HIV-1 tat protein
-
US5527894
-
Gold L, Tuerk C. Ligands of HIV-1 tat protein. US5527894; 1996
-
(1996)
-
-
Gold, L.1
Tuerk, C.2
-
84
-
-
68249090441
-
Prophylactic and therapeutic HIV aptamers
-
WO2004026260
-
Wilson C, Epstein D, Diener JL. Prophylactic and therapeutic HIV aptamers. WO2004026260; 2004
-
(2004)
-
-
Wilson, C.1
Epstein, D.2
Diener, J.L.3
-
85
-
-
68249131392
-
RNA molecule forming heterodimer and targeting NS3 protease of hepatitis C virus
-
JP2005151890
-
Nishikawa S, Sekiya S, Penmeccha K. RNA molecule forming heterodimer and targeting NS3 protease of hepatitis C virus. JP2005151890; 2005
-
(2005)
-
-
Nishikawa, S.1
Sekiya, S.2
Penmeccha, K.3
-
86
-
-
68249085977
-
Nuclease resistant RNA aptamer inhibiting replication of hepatitis C virus replicon
-
WO2008066231
-
Lee S-W, Shin K-S, Lim J-H, et al. Nuclease resistant RNA aptamer inhibiting replication of hepatitis C virus replicon. WO2008066231; 2008
-
(2008)
-
-
Lee, S.-W.1
Shin, K.-S.2
Lim, J.-H.3
-
87
-
-
68249102972
-
Oligonucleotide mediated inhibition of hepatitis B virus and hepatitis C virus replication
-
WO2002081494
-
Blatt L, Macejak D, Mcswiggen J, et al. Oligonucleotide mediated inhibition of hepatitis B virus and hepatitis C virus replication. WO2002081494; 2002
-
(2002)
-
-
Blatt, L.1
Macejak, D.2
Mcswiggen, J.3
-
88
-
-
68249086792
-
Capped synthetic RNA, analogs, and aptamers
-
US5861501
-
Benseler F, Cole JL, Olsen DB, Kuo LC. Capped synthetic RNA, analogs, and aptamers. US5861501; 1999
-
(1999)
-
-
Benseler, F.1
Cole, J.L.2
Olsen, D.B.3
Kuo, L.C.4
-
89
-
-
68249120674
-
Compositions and methods of developing oligonucleotides and oligonucleotide analogs having antiviral activity
-
WO1997020072
-
Wang J-F, Pan W. Compositions and methods of developing oligonucleotides and oligonucleotide analogs having antiviral activity. WO1997020072; 1997
-
(1997)
-
-
Wang, J.-F.1
Pan, W.2
-
90
-
-
17644408522
-
Methods and compositions for aptamers against anthrax
-
US6569630
-
Vivekananda J, Kiel JL. Methods and compositions for aptamers against anthrax. US6569630; 2003
-
(2003)
-
-
Vivekananda, J.1
Kiel, J.L.2
-
91
-
-
68249129634
-
Nulceic acid mediated inhibition of enterococcus infection and cytolysin toxin activity
-
WO2003106476
-
Morrissey D, Haeberli P. Nulceic acid mediated inhibition of enterococcus infection and cytolysin toxin activity. WO2003106476; 2003
-
(2003)
-
-
Morrissey, D.1
Haeberli, P.2
-
92
-
-
33646582037
-
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
-
Farokhzad OC, Cheng J, Teply BA, et al. Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc Natl Acad Sci USA 2006;103:6315-6320
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6315-6320
-
-
Farokhzad, O.C.1
Cheng, J.2
Teply, B.A.3
-
93
-
-
7444223607
-
Nanoparticle-aptamer bioconjugates: A new approach for targeting prostate cancer cells
-
DOI 10.1158/0008-5472.CAN-04-2550
-
Farokhzad OC, Jon S, Khademhosseini A, et al. Nanopartide-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res 2004;64:7668-7672 (Pubitemid 39446893)
-
(2004)
Cancer Research
, vol.64
, Issue.21
, pp. 7668-7672
-
-
Farokhzad, O.C.1
Jon, S.2
Khademhosseini, A.3
Tran, T.-N.T.4
Lavan, D.A.5
Langer, R.6
-
95
-
-
33745714275
-
Aptamer: Toxin conjugates that specifically target prostate tumor cells
-
Chu TC, Marks JW 3rd, Lavery LA, et al. Aptamer: toxin conjugates that specifically target prostate tumor cells. Cancer Res 2006;66:5989-5992
-
(2006)
Cancer Res
, vol.66
, pp. 5989-5992
-
-
Chu, T.C.1
Marks III, J.W.2
Lavery, L.A.3
-
96
-
-
33645238918
-
Labeling tumor cells with fluorescent nanocrystal-aptamer bioconjugates
-
Chu TC, Shieh F, Lavery LA, et al. Labeling tumor cells with fluorescent nanocrystal-aptamer bioconjugates. Biosens Bioelectron 2006;21:1859-1866
-
(2006)
Biosens Bioelectron
, vol.21
, pp. 1859-1866
-
-
Chu, T.C.1
Shieh, F.2
Lavery, L.A.3
-
99
-
-
68249098403
-
Aptamers t von Willebrand factor and their use as thrombotic disease therapeutics
-
US20060183702
-
Diener JL, Lagasse DHA, Benedict C. Aptamers t von Willebrand factor and their use as thrombotic disease therapeutics. US20060183702; 2006
-
(2006)
-
-
Diener, J.L.1
Lagasse, D.H.A.2
Benedict, C.3
-
100
-
-
48349086777
-
New strategies for in vivo tissue engineering by mimicry of homing factors for self-endothelialisation of blood contacting materials
-
Avci-Adali M, Paul A, Ziemer G, Wendel HP. New strategies for in vivo tissue engineering by mimicry of homing factors for self-endothelialisation of blood contacting materials. Biomaterials 2008;29:3936-3945
-
(2008)
Biomaterials
, vol.29
, pp. 3936-3945
-
-
Avci-Adali, M.1
Paul, A.2
Ziemer, G.3
Wendel, H.P.4
-
101
-
-
68249096639
-
High-affinity oligonucleotide ligands to the tachykinin substance P
-
US5648214
-
Nieuwlandt DT, Gold L, Wecker M. High-affinity oligonucleotide ligands to the tachykinin substance P. US5648214; 1997
-
(1997)
-
-
Nieuwlandt, D.T.1
Gold, L.2
Wecker, M.3
-
102
-
-
68249093243
-
Cathepsin G-inhibiting aptamers
-
US5780449
-
Bracht F, Schror K. Cathepsin G-inhibiting aptamers. US5780449; 1998
-
(1998)
-
-
Bracht, F.1
Schror, K.2
-
103
-
-
68249115436
-
Ucleic acid ligands of tissue target
-
US6127119
-
Stephens A, Gold L, Speck U. Nucleic acid ligands of tissue target. US6127119; 2000
-
(2000)
-
-
Stephens, A.1
Gold, L.2
Speck, U.N.3
-
104
-
-
68249100888
-
Nucleic acid ligands to CD40 ligand
-
US6171795
-
Korman AJ, Gold L. Nucleic acid ligands to CD40 ligand. US6171795; 2001
-
(2001)
-
-
Korman, A.J.1
Gold, L.2
-
105
-
-
68249108256
-
Nucleic acid ligand inhibitors to DNA polymerases
-
US6183967
-
Jayasena S, Gold L. Nucleic acid ligand inhibitors to DNA polymerases. US6183967; 2001
-
(2001)
-
-
Jayasena, S.1
Gold, L.2
-
106
-
-
68249119112
-
Nucleic acid capable of binding specifically to Ras target protein
-
WO2000009684
-
Yokoyama S, Hirao I, Sakamoto K. Nucleic acid capable of binding specifically to Ras target protein. WO2000009684; 2000
-
(2000)
-
-
Yokoyama, S.1
Hirao, I.2
Sakamoto, K.3
-
107
-
-
68249104890
-
Aptamers for complement protein C3b
-
WO1997042317
-
Lin A, Marsh HC Jr, Stewart SE. Aptamers for complement protein C3b. WO1997042317; 1997
-
(1997)
-
-
Lin, A.1
Marsh Jr., H.C.2
Stewart, S.E.3
-
108
-
-
68249125790
-
Regulated aptamer therapeutics
-
WO2004011680
-
Epstein D, Wilson C, Diener JL. Regulated aptamer therapeutics. WO2004011680; 2004
-
(2004)
-
-
Epstein, D.1
Wilson, C.2
Diener, J.L.3
-
109
-
-
68249112505
-
Vascular endothelial growth factor (VEGF) nucleic acid ligand
-
US5859228
-
Janjic N, Gold L, Schmidt P. Vascular endothelial growth factor (VEGF) nucleic acid ligand. US5859228; 1999
-
(1999)
-
-
Janjic, N.1
Gold, L.2
Schmidt, P.3
-
110
-
-
68249093744
-
Improved modulators of coagulation factors
-
WO2005106042
-
Rusconi C. Improved modulators of coagulation factors. WO2005106042; 2005
-
(2005)
-
-
Rusconi, C.1
-
111
-
-
68249098403
-
Aptamers to von willebrand factor and their use as thrombotic disease therapeutics
-
WO2006033854
-
Diener JL, Lagasse DHA. Aptamers to von willebrand factor and their use as thrombotic disease therapeutics. WO2006033854; 2006
-
(2006)
-
-
Diener, J.L.1
Lagasse, D.H.A.2
|