메뉴 건너뛰기




Volumn 14, Issue 9, 2014, Pages 640-646

Natural killer T cells: Drivers or passengers in preventing human disease?

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; TUMOR ANTIGEN; CD1D ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 4; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84906933853     PISSN: 14741733     EISSN: 14741741     Source Type: Journal    
DOI: 10.1038/nri3725     Document Type: Review
Times cited : (60)

References (124)
  • 3
    • 79251497664 scopus 로고    scopus 로고
    • Presumed guilty: Natural killer T cell defects and human disease
    • Berzins, S. P., Smyth, M. J. & Baxter, A. G. Presumed guilty: natural killer T cell defects and human disease. Nature Rev. Immunol. 11, 131-142 (2011).
    • (2011) Nature Rev. Immunol , vol.11 , pp. 131-142
    • Berzins, S.P.1    Smyth, M.J.2    Baxter, A.G.3
  • 4
    • 79960468556 scopus 로고    scopus 로고
    • NKT-cell-based immunotherapies in clinical trials
    • Exley, M. A. & Nakayama, T. NKT-cell-based immunotherapies in clinical trials. Clin. Immunol. 140, 117-118 (2011).
    • (2011) Clin. Immunol , vol.140 , pp. 117-118
    • Exley, M.A.1    Nakayama, T.2
  • 8
    • 79958251746 scopus 로고    scopus 로고
    • New ways to turn on NKT cells
    • Godfrey, D. I. & Rossjohn, J. New ways to turn on NKT cells. J. Exp. Med. 208, 1121-1125 (2011).
    • (2011) J. Exp. Med , vol.208 , pp. 1121-1125
    • Godfrey, D.I.1    Rossjohn, J.2
  • 9
    • 80052966551 scopus 로고    scopus 로고
    • Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria
    • Kinjo, Y. et al. Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria. Nature Immunol. 12, 966-974 (2011).
    • (2011) Nature Immunol , vol.12 , pp. 966-974
    • Kinjo, Y.1
  • 12
    • 84872943896 scopus 로고    scopus 로고
    • Invariant natural killer T cells: An innate activation scheme linked to diverse effector functions
    • Brennan, P. J., Brigl, M. & Brenner, M. B. Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions. Nature Rev. Immunol. 13, 101-117 (2013).
    • (2013) Nature Rev. Immunol , vol.13 , pp. 101-117
    • Brennan, P.J.1    Brigl, M.2    Brenner, M.B.3
  • 13
    • 84877073135 scopus 로고    scopus 로고
    • Natural killer T cell obsession with self-antigens
    • Gapin, L., Godfrey, D. I. & Rossjohn, J. Natural killer T cell obsession with self-antigens. Curr. Opin. Immunol. 25, 168-173 (2013).
    • (2013) Curr. Opin. Immunol , vol.25 , pp. 168-173
    • Gapin, L.1    Godfrey, D.I.2    Rossjohn, J.3
  • 14
    • 84902174556 scopus 로고    scopus 로고
    • Antigen-dependent versus-independent activation of invariant NKT cells during infection
    • Holzapfel, K. L., Tyznik, A. J., Kronenberg, M. & Hogquist, K. A. Antigen-dependent versus-independent activation of invariant NKT cells during infection. J. Immunol. 192, 5490-5498 (2014).
    • (2014) J. Immunol , vol.192 , pp. 5490-5498
    • Holzapfel, K.L.1    Tyznik, A.J.2    Kronenberg, M.3    Hogquist, K.A.4
  • 16
    • 0037018108 scopus 로고    scopus 로고
    • Distinct functional lineages of human Vα24 natural killer T cells
    • DOI 10.1084/jem.20011908
    • Lee, P. T., Benlagha, K., Teyton, L. & Bendelac, A. Distinct functional lineages of human Va24 natural killer T cells. J. Exp. Med. 195, 637-641 (2002). (Pubitemid 34461508)
    • (2002) Journal of Experimental Medicine , vol.195 , Issue.5 , pp. 637-641
    • Lee, P.T.1    Benlagha, K.2    Teyton, L.3    Bendelac, A.4
  • 17
    • 0036838607 scopus 로고    scopus 로고
    • Distinct subsets of human Vα24-invariant NKT cells: Cytokine responses and chemokine receptor expression
    • DOI 10.1016/S1471-4906(02)02323-2, PII S1471490602023232
    • Kim, C. H., Butcher, E. C. & Johnston, B. Distinct subsets of human Va24-invariant NKT cells: cytokine responses and chemokine receptor expression. Trends Immunol. 23, 516-519 (2002). (Pubitemid 35223543)
    • (2002) Trends in Immunology , vol.23 , Issue.11 , pp. 516-519
    • Kim, C.H.1    Butcher, E.C.2    Johnston, B.3
  • 18
    • 0037018101 scopus 로고    scopus 로고
    • Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining
    • DOI 10.1084/jem.20011786
    • Gumperz, J. E., Miyake, S., Yamamura, T. & Brenner, M. B. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J. Exp. Med. 195, 625-636 (2002). (Pubitemid 34461507)
    • (2002) Journal of Experimental Medicine , vol.195 , Issue.5 , pp. 625-636
    • Gumperz, J.E.1    Miyake, S.2    Yamamura, T.3    Brenner, M.B.4
  • 19
    • 44849083151 scopus 로고    scopus 로고
    • NKT cells in tumor immunity: Opposing subsets define a new immunoregulatory axis
    • Berzofsky, J. A. & Terabe, M. NKT cells in tumor immunity: opposing subsets define a new immunoregulatory axis. J. Immunol. 180, 3627-3635 (2008).
    • (2008) J. Immunol , vol.180 , pp. 3627-3635
    • Berzofsky, J.A.1    Terabe, M.2
  • 21
    • 63849276117 scopus 로고    scopus 로고
    • Harnessing human CD1d restricted T cells for tumor immunity: Progress and challenges
    • Dhodapkar, M. V. Harnessing human CD1d restricted T cells for tumor immunity: progress and challenges. Front. Biosci. 14, 796-807 (2009).
    • (2009) Front. Biosci , vol.14 , pp. 796-807
    • Dhodapkar, M.V.1
  • 23
    • 67349255227 scopus 로고    scopus 로고
    • Clinical application of NKT cell biology in type i (autoimmune) diabetes mellitus
    • Fletcher, M. T. & Baxter, A. G. Clinical application of NKT cell biology in type I (autoimmune) diabetes mellitus. Immunol. Cell Biol. 87, 315-323 (2009).
    • (2009) Immunol. Cell Biol , vol.87 , pp. 315-323
    • Fletcher, M.T.1    Baxter, A.G.2
  • 25
    • 77953794345 scopus 로고    scopus 로고
    • The many paths to asthma: Phenotype shaped by innate and adaptive immunity
    • Kim, H. Y., DeKruyff, R. H. & Umetsu, D. T. The many paths to asthma: phenotype shaped by innate and adaptive immunity. Nature Immunol. 11, 577-584 (2010).
    • (2010) Nature Immunol , vol.11 , pp. 577-584
    • Kim, H.Y.1    Dekruyff, R.H.2    Umetsu, D.T.3
  • 26
    • 84864742968 scopus 로고    scopus 로고
    • Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens
    • Holtzman, M. J. Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens. J. Clin. Invest. 122, 2741-2748 (2012).
    • (2012) J. Clin. Invest , vol.122 , pp. 2741-2748
    • Holtzman, M.J.1
  • 27
    • 77951666927 scopus 로고    scopus 로고
    • Natural killer T cells are important in the pathogenesis of asthma: The many pathways to asthma
    • Umetsu, D. T. & Dekruyff, R. H. Natural killer T cells are important in the pathogenesis of asthma: the many pathways to asthma. J. Allergy Clin. Immunol. 125, 975-979 (2010).
    • (2010) J. Allergy Clin. Immunol , vol.125 , pp. 975-979
    • Umetsu, D.T.1    Dekruyff, R.H.2
  • 29
    • 56849090964 scopus 로고    scopus 로고
    • The role of NKT cells in tumor immunity
    • Terabe, M. & Berzofsky, J. A. The role of NKT cells in tumor immunity. Adv. Cancer Res. 101, 277-348 (2008).
    • (2008) Adv. Cancer Res , vol.101 , pp. 277-348
    • Terabe, M.1    Berzofsky, J.A.2
  • 30
    • 0034695880 scopus 로고    scopus 로고
    • Differential tumor surveillance by natural killer (NK) and NKT cells
    • Smyth, M. J. et al. Differential tumor surveillance by natural killer (NK) and NKT cells. J. Exp. Med. 191, 661-668 (2000).
    • (2000) J. Exp. Med , vol.191 , pp. 661-668
    • Smyth, M.J.1
  • 31
    • 67650609686 scopus 로고    scopus 로고
    • Type i natural killer T cells suppress tumors caused by p53 loss in mice
    • Swann, J. B. et al. Type I natural killer T cells suppress tumors caused by p53 loss in mice. Blood 113, 6382-6385 (2009).
    • (2009) Blood , vol.113 , pp. 6382-6385
    • Swann, J.B.1
  • 33
    • 70450185055 scopus 로고    scopus 로고
    • Decrease in intrahepatic CD56+ lymphocytes in gastric and colorectal cancer patients with liver metastases
    • Gulubova, M., Manolova, I., Kyurkchiev, D., Julianov, A. & Altunkova, I. Decrease in intrahepatic CD56+ lymphocytes in gastric and colorectal cancer patients with liver metastases. APMIS 117, 870-879 (2009).
    • (2009) APMIS , vol.117 , pp. 870-879
    • Gulubova, M.1    Manolova, I.2    Kyurkchiev, D.3    Julianov, A.4    Altunkova, I.5
  • 34
    • 9144257299 scopus 로고    scopus 로고
    • The characteristics of human NKT cells in lung cancer - CD1d independent cytotoxicity against lung cancer cells by NKT cells and decreased human NKT cell response in lung cancer patients
    • DOI 10.1016/j.humimm.2004.09.003, PII S0198885904006238
    • Konishi, J. et al. The characteristics of human NKT cells in lung cancer-CD1d independent cytotoxicity against lung cancer cells by NKT cells and decreased human NKT cell response in lung cancer patients. Hum. Immunol. 65, 1377-1388 (2004). (Pubitemid 39539204)
    • (2004) Human Immunology , vol.65 , Issue.11 , pp. 1377-1388
    • Konishi, J.1    Yamazaki, K.2    Yokouchi, H.3    Shinagawa, N.4    Iwabuchi, K.5    Nishimura, M.6
  • 36
    • 79955006106 scopus 로고    scopus 로고
    • Invariant NKT cell reconstitution in pediatric leukemia patients given HLA-haploidentical stem cell transplantation defines distinct CD4+ and CD4-subset dynamics and correlates with remission state
    • de Lalla, C. et al. Invariant NKT cell reconstitution in pediatric leukemia patients given HLA-haploidentical stem cell transplantation defines distinct CD4+ and CD4-subset dynamics and correlates with remission state. J. Immunol. 186, 4490-4499 (2011).
    • (2011) J. Immunol , vol.186 , pp. 4490-4499
    • De Lalla, C.1
  • 37
    • 84866140213 scopus 로고    scopus 로고
    • Early posttransplantation donorderived invariant natural killer T-cell recovery predicts the occurrence of acute graft-versus-host disease and overall survival
    • Rubio, M. T. et al. Early posttransplantation donorderived invariant natural killer T-cell recovery predicts the occurrence of acute graft-versus-host disease and overall survival. Blood 120, 2144-2154 (2012).
    • (2012) Blood , vol.120 , pp. 2144-2154
    • Rubio, M.T.1
  • 38
    • 79851515703 scopus 로고    scopus 로고
    • Induction of NKT cell-specific immune responses in cancer tissues after NKT celltargeted adoptive immunotherapy
    • Yamasaki, K. et al. Induction of NKT cell-specific immune responses in cancer tissues after NKT celltargeted adoptive immunotherapy. Clin. Immunol. 138, 255-265 (2011).
    • (2011) Clin. Immunol , vol.138 , pp. 255-265
    • Yamasaki, K.1
  • 39
    • 84892171393 scopus 로고    scopus 로고
    • NKT cells as an ideal anti-tumor immunotherapeutic
    • Fujii, S. I. et al. NKT cells as an ideal anti-tumor immunotherapeutic. Front. Immunol. 4, 409 (2013).
    • (2013) Front. Immunol , vol.4 , pp. 409
    • Fujii, S.I.1
  • 40
    • 51549118539 scopus 로고    scopus 로고
    • Congenic analysis of the NKT cell control gene Nkt2 implicates the peroxisomal protein Pxmp4
    • Fletcher, J. M. et al. Congenic analysis of the NKT cell control gene Nkt2 implicates the peroxisomal protein Pxmp4. J. Immunol. 181, 3400-3412 (2008).
    • (2008) J. Immunol , vol.181 , pp. 3400-3412
    • Fletcher, J.M.1
  • 41
    • 62749198174 scopus 로고    scopus 로고
    • Natural killer T cells and autoimmune disease
    • Wu, L. & Van Kaer, L. Natural killer T cells and autoimmune disease. Curr. Mol. Med. 9, 4-14 (2009).
    • (2009) Curr. Mol. Med , vol.9 , pp. 4-14
    • Wu, L.1    Van Kaer, L.2
  • 42
    • 84870424721 scopus 로고    scopus 로고
    • Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: Are we close to reality?
    • Simoni, Y., Diana, J., Ghazarian, L., Beaudoin, L. & Lehuen, A. Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality? Clin. Exp. Immunol. 171, 8-19 (2013).
    • (2013) Clin. Exp. Immunol , vol.171 , pp. 8-19
    • Simoni, Y.1    Diana, J.2    Ghazarian, L.3    Beaudoin, L.4    Lehuen, A.5
  • 43
    • 33644986351 scopus 로고    scopus 로고
    • CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma
    • Akbari, O. et al. CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma. N. Engl. J. Med. 354, 1117-1129 (2006).
    • (2006) N. Engl. J. Med , vol.354 , pp. 1117-1129
    • Akbari, O.1
  • 44
    • 67349188780 scopus 로고    scopus 로고
    • Natural killer T cells in the lungs of patients with asthma
    • Matangkasombut, P. et al. Natural killer T cells in the lungs of patients with asthma. J. Allergy Clin. Immunol. 123, 1181-1185 (2009).
    • (2009) J. Allergy Clin. Immunol , vol.123 , pp. 1181-1185
    • Matangkasombut, P.1
  • 46
    • 70449722931 scopus 로고    scopus 로고
    • Natural killer T cells in bronchial biopsies from human allergen challenge model of allergic asthma
    • Reynolds, C. et al. Natural killer T cells in bronchial biopsies from human allergen challenge model of allergic asthma. J. Allergy Clin. Immunol. 124, 860-862 (2009).
    • (2009) J. Allergy Clin. Immunol , vol.124 , pp. 860-862
    • Reynolds, C.1
  • 47
    • 77957761029 scopus 로고    scopus 로고
    • Invariant natural killer T cells and asthma: Immunologic reality or methodologic artifact?
    • Brooks, C. R., Weinkove, R., Hermans, I. F., van Dalen, C. J. & Douwes, J. Invariant natural killer T cells and asthma: immunologic reality or methodologic artifact? J. Allergy Clin. Immunol. 126, 882-885 (2010).
    • (2010) J. Allergy Clin. Immunol , vol.126 , pp. 882-885
    • Brooks, C.R.1    Weinkove, R.2    Hermans, I.F.3    Van Dalen, C.J.4    Douwes, J.5
  • 48
    • 0034742480 scopus 로고    scopus 로고
    • Circulating Va24+ Vß11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage
    • van der Vliet, H. J. J. et al. Circulating Va24+ Vß11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage. Clin. Immunol. 100, 144-148 (2001).
    • (2001) Clin. Immunol , vol.100 , pp. 144-148
    • Van Der Vliet, H.J.J.1
  • 49
    • 18844432751 scopus 로고    scopus 로고
    • Limited correlation between human thymus and blood NKT cell content revealed by an ontogeny study of paired tissue samples
    • DOI 10.1002/eji.200425958
    • Berzins, S. P., Cochrane, A. D., Pellicci, D. G., Smyth, M. J. & Godfrey, D. I. Limited correlation between human thymus and blood NKT cell content revealed by an ontogeny study of paired tissue samples. Eur. J. Immunol. 35, 1399-1407 (2005). (Pubitemid 40691421)
    • (2005) European Journal of Immunology , vol.35 , Issue.5 , pp. 1399-1407
    • Berzins, S.P.1    Cochrane, A.D.2    Pellicci, D.G.3    Smyth, M.J.4    Godfrey, D.I.5
  • 51
    • 79960448230 scopus 로고    scopus 로고
    • Anti-tumor potential of type-I NKT cells against CD1d-positive and CD1d-negative tumors in humans
    • Metelitsa, L. S. Anti-tumor potential of type-I NKT cells against CD1d-positive and CD1d-negative tumors in humans. Clin. Immunol. 140, 119-129 (2011).
    • (2011) Clin. Immunol , vol.140 , pp. 119-129
    • Metelitsa, L.S.1
  • 54
    • 34047177067 scopus 로고    scopus 로고
    • The in vivo response of invariant natural killer T cells to glycolipid antigens
    • DOI 10.1080/08830180601070179, PII 776080054
    • Parekh, V. V., Lalani, S. & Van Kaer, L. The in vivo response of invariant natural killer T cells to glycolipid antigens. Int. Rev. Immunol. 26, 31-48 (2007). (Pubitemid 46512168)
    • (2007) International Reviews of Immunology , vol.26 , Issue.1-2 , pp. 31-48
    • Parekh, V.V.1    Lalani, S.2    Van Kaer, L.3
  • 55
    • 0037787982 scopus 로고    scopus 로고
    • Activation of natural killer T cells by α-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein
    • DOI 10.1084/jem.20030324
    • Fujii, S., Shimizu, K., Smith, C., Bonifaz, L. & Steinman, R. M. Activation of natural killer T cells by a-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein. J. Exp. Med. 198, 267-279 (2003). (Pubitemid 36987852)
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.2 , pp. 267-279
    • Fujii, S.-I.1    Shimizu, K.2    Smith, C.3    Bonifaz, L.4    Steinman, R.M.5
  • 56
    • 77953539101 scopus 로고    scopus 로고
    • Synthetic iNKT cell-agonists as vaccine adjuvants-finding the balance
    • Cerundolo, V., Barral, P. & Batista, F. D. Synthetic iNKT cell-agonists as vaccine adjuvants-finding the balance. Curr. Opin. Immunol. 22, 417-424 (2010).
    • (2010) Curr. Opin. Immunol , vol.22 , pp. 417-424
    • Cerundolo, V.1    Barral, P.2    Batista, F.D.3
  • 57
    • 79960444343 scopus 로고    scopus 로고
    • Anti-tumor immune responses induced by iNKT cell-based immunotherapy for lung cancer and head and neck cancer
    • Motohashi, S., Okamoto, Y., Yoshino, I. & Nakayama, T. Anti-tumor immune responses induced by iNKT cell-based immunotherapy for lung cancer and head and neck cancer. Clin. Immunol. 140, 167-176 (2011).
    • (2011) Clin. Immunol , vol.140 , pp. 167-176
    • Motohashi, S.1    Okamoto, Y.2    Yoshino, I.3    Nakayama, T.4
  • 60
    • 57449096122 scopus 로고    scopus 로고
    • A prescription for human immunology
    • Davis, M. M. A prescription for human immunology. Immunity 29, 835-838 (2008).
    • (2008) Immunity , vol.29 , pp. 835-838
    • Davis, M.M.1
  • 61
    • 79955612071 scopus 로고    scopus 로고
    • Mucosal-associated invariant T cells: Unconventional development and function
    • Le Bourhis, L. et al. Mucosal-associated invariant T cells: unconventional development and function. Trends Immunol. 32, 212-218 (2011).
    • (2011) Trends Immunol , vol.32 , pp. 212-218
    • Le Bourhis, L.1
  • 62
    • 79251585935 scopus 로고    scopus 로고
    • Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells
    • Dusseaux, M. et al. Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells. Blood 117, 1250-1259 (2011).
    • (2011) Blood , vol.117 , pp. 1250-1259
    • Dusseaux, M.1
  • 63
    • 84864116698 scopus 로고    scopus 로고
    • Lower TCR repertoire diversity in Traj18-deficient mice
    • Bedel, R. et al. Lower TCR repertoire diversity in Traj18-deficient mice. Nature Immunol. 13, 705-706 (2012).
    • (2012) Nature Immunol , vol.13 , pp. 705-706
    • Bedel, R.1
  • 65
    • 0033870526 scopus 로고    scopus 로고
    • Comparison of the T cell patterns in leprous and cutaneous sarcoid granulomas: Presence of Vα24-invariant natural killer T cells in T-cell-reactive leprosy together with a highly biased T cell receptor Vα repertoire
    • Mempel, M. et al. Comparison of the T cell patterns in leprous and cutaneous sarcoid granulomas. Presence of Vα24-invariant natural killer T cells in T-cell-reactive leprosy together with a highly biased T cell receptor Vα repertoire. Am. J. Pathol. 157, 509-523 (2000). (Pubitemid 30627561)
    • (2000) American Journal of Pathology , vol.157 , Issue.2 , pp. 509-523
    • Mempel, M.1    Flageul, B.2    Suarez, F.3    Ronet, C.4    Dubertret, L.5    Kourilsky, P.6    Gachelin, G.7    Musette, P.8
  • 66
    • 70149106669 scopus 로고    scopus 로고
    • NKT cells mediate pulmonary inflammation and dysfunction in murine sickle cell disease through production of IFN-γ and CXCR3 chemokines
    • Wallace, K. L. et al. NKT cells mediate pulmonary inflammation and dysfunction in murine sickle cell disease through production of IFN-γ and CXCR3 chemokines. Blood 114, 667-676 (2009).
    • (2009) Blood , vol.114 , pp. 667-676
    • Wallace, K.L.1
  • 68
    • 34249059942 scopus 로고    scopus 로고
    • Identification of an IL-17-producing NK1.1neg iNKT cell population involved in airway neutrophilia
    • Michel, M. L. et al. Identification of an IL-17-producing NK1.1neg iNKT cell population involved in airway neutrophilia. J. Exp. Med. 204, 995-1001 (2007).
    • (2007) J. Exp. Med , vol.204 , pp. 995-1001
    • Michel, M.L.1
  • 69
    • 49649123906 scopus 로고    scopus 로고
    • Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1-NKT cell population
    • Coquet, J. M. et al. Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1-NKT cell population. Proc. Natl Acad. Sci. USA 105, 11287-11292 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 11287-11292
    • Coquet, J.M.1
  • 71
    • 0036645278 scopus 로고    scopus 로고
    • A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas
    • DOI 10.1084/jem.20020092
    • Crowe, N. Y., Smyth, M. J. & Godfrey, D. I. A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas. J. Exp. Med. 196, 119-127 (2002). (Pubitemid 34747317)
    • (2002) Journal of Experimental Medicine , vol.196 , Issue.1 , pp. 119-127
    • Crowe, N.Y.1    Smyth, M.J.2    Godfrey, D.I.3
  • 72
    • 84864453237 scopus 로고    scopus 로고
    • And IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin)
    • Kammertoens, T., Qin, Z., Briesemeister, D., Bendelac, A. & Blankenstein, T. B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin). Int. J. Cancer 131, 1499-1508 (2012).
    • (2012) Int. J. Cancer , vol.131 , pp. 1499-1508
    • Kammertoens, T.1    Qin, Z.2    Briesemeister, D.3    Bendelac, A.4    B-Cells, B.T.5
  • 73
    • 77955321049 scopus 로고    scopus 로고
    • Defective NKT cell activation by CD1d+ TRAMP prostate tumor cells is corrected by interleukin-12 with α-galactosylceramide
    • Nowak, M. et al. Defective NKT cell activation by CD1d+ TRAMP prostate tumor cells is corrected by interleukin-12 with α-galactosylceramide. PLoS ONE 5, e11311 (2010).
    • (2010) PLoS ONE , vol.5
    • Nowak, M.1
  • 75
    • 33747511125 scopus 로고    scopus 로고
    • + NKT cell-mediated cytotoxicity
    • DOI 10.1002/ijc.22019
    • Mattarollo, S. R., Kenna, T., Nieda, M. & Nicol, A. J. Chemotherapy pretreatment sensitizes solid tumor-derived cell lines to Vα24+ NKT cell-mediated cytotoxicity. Int. J. Cancer 119, 1630-1637 (2006). (Pubitemid 44258769)
    • (2006) International Journal of Cancer , vol.119 , Issue.7 , pp. 1630-1637
    • Mattarollo, S.R.1    Kenna, T.2    Nieda, M.3    Nicol, A.J.4
  • 76
    • 35748954102 scopus 로고    scopus 로고
    • Cross-presentation of glycolipid from tumor cells loaded with α-galactosylceramide leads to potent and long-lived T cell-mediated immunity via dendritic cells
    • DOI 10.1084/jem.20070458
    • Shimizu, K., Kurosawa, Y., Taniguchi, M., Steinman, R. M. & Fujii, S. Cross-presentation of glycolipid from tumor cells loaded with α-galactosylceramide leads to potent and long-lived T cell mediated immunity via dendritic cells. J. Exp. Med. 204, 2641-2653 (2007). (Pubitemid 350063944)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.11 , pp. 2641-2653
    • Shimizu, K.1    Kurosawa, Y.2    Taniguchi, M.3    Steinman, R.M.4    Fujii, S.-I.5
  • 77
    • 66349083007 scopus 로고    scopus 로고
    • Vα24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages
    • Song, L. et al. Vα24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages. J. Clin. Invest. 119, 1524-1536 (2009).
    • (2009) J. Clin. Invest , vol.119 , pp. 1524-1536
    • Song, L.1
  • 79
    • 77955554522 scopus 로고    scopus 로고
    • The effect of radiotherapy on NKT cells in patients with advanced head and neck cancer
    • Kobayashi, K. et al. The effect of radiotherapy on NKT cells in patients with advanced head and neck cancer. Cancer Immunol. Immunother. 59, 1503-1509 (2010).
    • (2010) Cancer Immunol. Immunother , vol.59 , pp. 1503-1509
    • Kobayashi, K.1
  • 81
    • 69249155107 scopus 로고    scopus 로고
    • Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity
    • Lynch, L. et al. Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity. Eur. J. Immunol. 39, 1893-1901 (2009).
    • (2009) Eur. J. Immunol , vol.39 , pp. 1893-1901
    • Lynch, L.1
  • 82
    • 27144471372 scopus 로고    scopus 로고
    • Increased intratumor Vα24-positive natural killer T cells: A prognostic factor for primary colorectal carcinomas
    • DOI 10.1158/1078-0432.CCR-05-0877
    • Tachibana, T. et al. Increased intratumor Vα24-positive natural killer T cells: a prognostic factor for primary colorectal carcinomas. Clin. Cancer Res. 11, 7322-7327 (2005). (Pubitemid 41507690)
    • (2005) Clinical Cancer Research , vol.11 , Issue.20 , pp. 7322-7327
    • Tachibana, T.1    Onodera, H.2    Tsuruyama, T.3    Mori, A.4    Nagayama, S.5    Hiai, H.6    Imamura, M.7
  • 83
    • 65249176389 scopus 로고    scopus 로고
    • Enrichment of human CD4+ Vα24/Vβ11 invariant NKT cells in intrahepatic malignant tumors
    • Bricard, G. et al. Enrichment of human CD4+ Vα24/Vβ11 invariant NKT cells in intrahepatic malignant tumors. J. Immunol. 182, 5140-5151 (2009).
    • (2009) J. Immunol , vol.182 , pp. 5140-5151
    • Bricard, G.1
  • 86
    • 0043163751 scopus 로고    scopus 로고
    • Severe and selective deficiency of interferon-γ-producing invariant natural killer T cells in patients with myelodysplastic syndromes
    • DOI 10.1046/j.1365-2141.2003.04465.x
    • Fujii, S. et al. Severe and selective deficiency of interferon-gamma- producing invariant natural killer T cells in patients with myelodysplastic syndromes. Br. J. Haematol. 122, 617-622 (2003). (Pubitemid 36995216)
    • (2003) British Journal of Haematology , vol.122 , Issue.4 , pp. 617-622
    • Fujii, S.-I.1    Shimizu, K.2    Klimek, V.3    Geller, M.D.4    Nimer, S.D.5    Dhodapkar, M.V.6
  • 88
    • 77949423620 scopus 로고    scopus 로고
    • Testing the NKT cell hypothesis in lenalidomide-treated myelodysplastic syndrome patients
    • Chan, A. C. et al. Testing the NKT cell hypothesis in lenalidomide-treated myelodysplastic syndrome patients. Leukemia 24, 592-600 (2010).
    • (2010) Leukemia , vol.24 , pp. 592-600
    • Chan, A.C.1
  • 89
    • 84888863785 scopus 로고    scopus 로고
    • Natural killer T cell defects in multiple myeloma and the impact of lenalidomide therapy
    • Chan, A. C. et al. Natural killer T cell defects in multiple myeloma and the impact of lenalidomide therapy. Clin. Exp. Immunol. 175, 49-58 (2014).
    • (2014) Clin. Exp. Immunol , vol.175 , pp. 49-58
    • Chan, A.C.1
  • 90
    • 79960450420 scopus 로고    scopus 로고
    • Clinical experience with alpha-galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection
    • Schneiders, F. L. et al. Clinical experience with alpha- galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection. Clin. Immunol. 140, 130-141 (2011).
    • (2011) Clin. Immunol , vol.140 , pp. 130-141
    • Schneiders, F.L.1
  • 92
    • 0033022704 scopus 로고    scopus 로고
    • Immunization with α-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis
    • DOI 10.1002/ (SICI) 1521-4141 (199906) 29:06<2014::AID-IMMU2014>3. 0.CO;2-G
    • Burdin, N., Brossay, L. & Kronenberg, M. Immunization with α-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis. Eur. J. Immunol. 29, 2014-2025 (1999). (Pubitemid 29265558)
    • (1999) European Journal of Immunology , vol.29 , Issue.6 , pp. 2014-2025
    • Burdin, N.1    Brossay, L.2    Kronenberg, M.3
  • 93
    • 0042173087 scopus 로고    scopus 로고
    • Polarization of Vα24+ Vβ11+ natural killer T cells of healthy volunteers and cancer patients using α-galactosylceramide-loaded and environmentally instructed dendritic cells
    • van der Vliet, H. J. et al. Polarization of Vα24+ Vβ11+ natural killer T cells of healthy volunteers and cancer patients using α-galactosylceramide-loaded and environmentally instructed dendritic cells. Cancer Res. 63, 4101-4106 (2003).
    • (2003) Cancer Res , vol.63 , pp. 4101-4106
    • Van Der Vliet, H.J.1
  • 94
    • 58149241014 scopus 로고    scopus 로고
    • Generation of antitumor invariant natural killer T cell lines in multiple myeloma and promotion of their functions via lenalidomide: A strategy for immunotherapy
    • Song, W. et al. Generation of antitumor invariant natural killer T cell lines in multiple myeloma and promotion of their functions via lenalidomide: a strategy for immunotherapy. Clin. Cancer Res. 14, 6955-6962 (2008).
    • (2008) Clin. Cancer Res , vol.14 , pp. 6955-6962
    • Song, W.1
  • 95
    • 52549088421 scopus 로고    scopus 로고
    • Immunomodulatory drugs Revlimid (lenalidomide) and CC-4047 induce apoptosis of both hematological and solid tumor cells through NK cell activation
    • Zhu, D., Corral, L. G., Fleming, Y. W. & Stein, B. Immunomodulatory drugs Revlimid (lenalidomide) and CC-4047 induce apoptosis of both hematological and solid tumor cells through NK cell activation. Cancer Immunol. Immunother. 57, 1849-1859 (2008).
    • (2008) Cancer Immunol. Immunother , vol.57 , pp. 1849-1859
    • Zhu, D.1    Corral, L.G.2    Fleming, Y.W.3    Stein, B.4
  • 96
    • 33745961875 scopus 로고    scopus 로고
    • Enhancement of ligand-dependent activation of human natural killer T cells by lenalidomide: Therapeutic implications
    • DOI 10.1182/blood-2005-10-4184
    • Chang, D. H. et al. Enhancement of ligand-dependent activation of human natural killer T cells by lenalidomide: therapeutic implications. Blood 108, 618-621 (2006). (Pubitemid 44061362)
    • (2006) Blood , vol.108 , Issue.2 , pp. 618-621
    • Chang, D.H.1    Liu, N.2    Klimek, V.3    Hassoun, H.4    Mazumder, A.5    Nimer, S.D.6    Jagannath, S.7    Dhodapkar, M.V.8
  • 98
    • 0030615214 scopus 로고    scopus 로고
    • - T-cell deficiency and IDDM in NOD/Lt mice
    • Baxter, A. G., Kinder, S. J., Hammond, K. J. L., Scollay, R. & Godfrey, D. I. Association between α-β-TCR+CD4-CD8-T-cell deficiency and IDDM in NOD/Lt mice. Diabetes 46, 572-582 (1997). (Pubitemid 27143372)
    • (1997) Diabetes , vol.46 , Issue.4 , pp. 572-582
    • Baxter, A.G.1    Kinder, S.J.2    Hammond, K.J.L.3    Scollay, R.4    Godfrey, D.I.5
  • 99
    • 0031171897 scopus 로고    scopus 로고
    • - thymocytes
    • DOI 10.1006/jaut.1997.0129
    • Godfrey, D. I., Kinder, S. J., Silvera, P. & Baxter, A. G. Flow cytometric study of T cell development in NOD mice reveals a deficiency in αβTCR+CDR-CD8-thymocytes. J. Autoimmun 10, 279-285 (1997). (Pubitemid 27286535)
    • (1997) Journal of Autoimmunity , vol.10 , Issue.3 , pp. 279-285
    • Godfrey, D.I.1    Kinder, S.J.2    Silvera, P.3    Baxter, A.G.4
  • 100
    • 0035659927 scopus 로고    scopus 로고
    • Clinical application of NKT cell assays to the prediction of type 1 diabetes
    • DOI 10.1002/dmrr.238
    • Poulton, L. D. & Baxter, A. G. Clinical application of NKT cell assays to the prediction of type 1 diabetes. Diabetes Metab. Res. Rev. 17, 429-435 (2001). (Pubitemid 34030745)
    • (2001) Diabetes/Metabolism Research and Reviews , vol.17 , Issue.6 , pp. 429-435
    • Poulton, L.D.1    Baxter, A.G.2
  • 101
    • 0032489860 scopus 로고    scopus 로고
    • - (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10
    • DOI 10.1084/jem.187.7.1047
    • Hammond, K. J. L. et al. T cell receptor (TCR)+CD4-CD8-(NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10. J. Exp. Med. 187, 1047-1056 (1998). (Pubitemid 28176405)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.7 , pp. 1047-1056
    • Hammond, K.J.L.1    Poulton, L.D.2    Palmisano, L.J.3    Silveira, P.A.4    Godfrey, D.I.5    Baxter, A.G.6
  • 102
    • 0036906618 scopus 로고    scopus 로고
    • NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic β cells
    • DOI 10.1016/S1074-7613(02)00473-9
    • Beaudoin, L., Laloux, V., Novak, J., Lucas, B. & Lehuen, A. NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic β cells. Immunity 17, 725-736 (2002). (Pubitemid 35477792)
    • (2002) Immunity , vol.17 , Issue.6 , pp. 725-736
    • Beaudoin, L.1    Laloux, V.E.2    Novak, J.3    Lucas, B.4    Lehuen, A.5
  • 107
    • 33748500822 scopus 로고    scopus 로고
    • + regulatory T cells
    • Ly, D., Mi, Q. S., Hussain, S. & Delovitch, T. L. Protection from type 1 diabetes by invariant NK T cells requires the activity of CD4+CD25+ regulatory T cells. J. Immunol. 177, 3695-3704 (2006). (Pubitemid 44359901)
    • (2006) Journal of Immunology , vol.177 , Issue.6 , pp. 3695-3704
    • Ly, D.1    Mi, Q.-S.2    Hussain, S.3    Delovitch, T.L.4
  • 108
    • 84899494386 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells license regulatory T cells, upon iNKT-cell stimulation, to prevent autoimmune diabetes
    • Beaudoin, L. et al. Plasmacytoid dendritic cells license regulatory T cells, upon iNKT-cell stimulation, to prevent autoimmune diabetes. Eur. J. Immunol. 44, 1454-1466 (2014).
    • (2014) Eur. J. Immunol , vol.44 , pp. 1454-1466
    • Beaudoin, L.1
  • 112
    • 33748745463 scopus 로고    scopus 로고
    • Phenotypic and genetic analyses of T-cell-mediated immunoregulation in patients with Type 1 diabetes
    • DOI 10.1111/j.1464-5491.2006.01951.x
    • Tsutsumi, Y. et al. Phenotypic and genetic analyses of T-cell-mediated immunoregulation in patients with type 1 diabetes. Diabet Med. 23, 1145-1150 (2006). (Pubitemid 44401147)
    • (2006) Diabetic Medicine , vol.23 , Issue.10 , pp. 1145-1150
    • Tsutsumi, Y.1    Jie, X.2    Ihara, K.3    Nomura, A.4    Kanemitsu, S.5    Takada, H.6    Hara, T.7
  • 113
    • 62949234386 scopus 로고    scopus 로고
    • Frequency and function of circulating invariant NKT cells in autoimmune diabetes mellitus and thyroid diseases in Colombian patients
    • Roman-Gonzalez, A. et al. Frequency and function of circulating invariant NKT cells in autoimmune diabetes mellitus and thyroid diseases in Colombian patients. Hum. Immunol. 70, 262-268 (2009).
    • (2009) Hum. Immunol , vol.70 , pp. 262-268
    • Roman-Gonzalez, A.1
  • 117
    • 0038387445 scopus 로고    scopus 로고
    • To respond or not to respond: T cells in allergic asthma
    • DOI 10.1038/nri1084
    • Herrick, C. A. & Bottomly, K. To respond or not to respond: T cells in allergic asthma. Nature Rev. Immunol. 3, 405-412 (2003). (Pubitemid 37323200)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.5 , pp. 405-412
    • Herrick, C.A.1    Bottomly, K.2
  • 118
    • 34047131864 scopus 로고    scopus 로고
    • Natural killer T cells regulate the development of asthma
    • DOI 10.1080/08830180601070237, PII 776081348
    • Umetsu, D. T., Meyer, E. H. & DeKruyff, R. H. Natural killer T cells regulate the development of asthma. Int. Rev. Immunol. 26, 121-140 (2007). (Pubitemid 46512171)
    • (2007) International Reviews of Immunology , vol.26 , Issue.1-2 , pp. 121-140
    • Umetsu, D.T.1    Meyer, E.H.2    DeKruyff, R.H.3
  • 120
    • 82255194202 scopus 로고    scopus 로고
    • NOD mice contain an elevated frequency of iNKT17 cells that exacerbate diabetes
    • Simoni, Y. et al. NOD mice contain an elevated frequency of iNKT17 cells that exacerbate diabetes. Eur. J. Immunol. 41, 3574-3585 (2011).
    • (2011) Eur. J. Immunol , vol.41 , pp. 3574-3585
    • Simoni, Y.1
  • 121
    • 0026610142 scopus 로고
    • H2-like bronchoalveolar T-lymphocyte population in atopic asthma
    • Robinson, D. S. et al. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med. 326, 298-304 (1992).
    • (1992) N. Engl. J. Med , vol.326 , pp. 298-304
    • Robinson, D.S.1
  • 122
    • 33644504477 scopus 로고    scopus 로고
    • Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells
    • Meyer, E. H. et al. Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells. Proc. Natl Acad. Sci. USA 103, 2782-2787 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 2782-2787
    • Meyer, E.H.1
  • 124
    • 34250849637 scopus 로고    scopus 로고
    • Control points in NKT-cell development
    • DOI 10.1038/nri2116, PII NRI2116
    • Godfrey, D. I. & Berzins, S. P. Control points in NKT-cell development. Nature Rev. Immunol. 7, 505-518 (2007). (Pubitemid 46987785)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.7 , pp. 505-518
    • Godfrey, D.I.1    Berzins, S.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.