New ways to turn on NKT cells

Journal of Experimental Medicine

Volumn 208, Issue 6, 2011, Pages 1121-1125

  Godfrey, Dale Ian ^a   Rossjohn, Jamie ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; GALACTOSYLDIACYLGLYCEROL; GLYCEROL DERIVATIVE; HOUSE DUST ALLERGEN; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; OVALBUMIN; SPHINGOLIPID; TOLL LIKE RECEPTOR;

ASTHMA; BORRELIA BURGDORFERI; CELL ACTIVATION; CELL LINEAGE; CELLULAR IMMUNITY; HOUSE DUST; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; INNATE IMMUNITY; MYCOBACTERIUM BOVIS; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; SPHINGOMONAS; STREPTOCOCCUS PNEUMONIAE; UPPER RESPIRATORY TRACT INFECTION;

ANIMALS; ANTIGENS, CD1D; CYTOKINES; GALACTOSYLCERAMIDES; GLYCOLIPIDS; HUMANS; IMMUNE SYSTEM; INFLAMMATION; LIPIDS; LYMPHOCYTE ACTIVATION; MICE; MODELS, BIOLOGICAL; NATURAL KILLER T-CELLS;

EID: 79958251746     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20110983     Document Type: Short Survey

References (40)

1. Agea, E., A. Russano, O. Bistoni, R. Mannucci, I. Nicoletti, L. Corazzi, A.D. Postle, G. De Libero, S.A. Porcelli, and F. Spinozzi. 2005. Human CD1-restricted T cell recognition of lipids from pollens. J. Exp. Med. 202:295-308.
2. Batzer, G., D.P. Lam, P. Paulus, J. Boasen, N. Ng, and A.A. Horner. 2007. Using house dust extracts to understand the immunostimulatory activities of living environments. Immunobiology. 212:491-498.
3. Borg, N.A., K.S. Wun, L. Kjer-Nielsen, M.C. Wilce, D.G. Pellicci, R. Koh, G.S. Besra, M. Bharadwaj, D.I. Godfrey, J. McCluskey, and J. Rossjohn. 2007. CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature. 448:44-49.
4. Brigl, M., and M.B. Brenner. 2010. How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens. Semin. Immunol. 22:79-86.
5. Brigl, M., L. Bry, S.C. Kent, J.E. Gumperz, and M.B. Brenner. 2003. Mechanism of CD1drestricted natural killer T cell activation during microbial infection. Nat. Immunol. 4:1230- 1237.
6. Brigl, M., R.V. Tatituri, G.F.M. Watts, V. Bhowruth, E.A. Leadbetter, N. Barton, N.R. Cohen, F.-F. Hsu, G.S. Besra, and M.B. Brenner. 2011. Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection. J. Exp. Med. 208:1163-1177.
7. Cerundolo, V., J.D. Silk, S.H. Masri, and M. Salio. 2009. Harnessing invariant NKT cells in vaccination strategies. Nat. Rev. Immunol. 9:28-38.
8. Chang, Y.J., H.Y. Kim, L.A. Albacker, H.H. Lee, N. Baumgarth, S. Akira, P.B. Savage, S. Endo, T. Yamamura, J. Maaskant, et al. 2011. Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity. J. Clin. Invest. 121:57-69.
9. Darmoise, A., S. Teneberg, L. Bouzonville, R.O. Brady, M. Beck, S.H. Kaufmann, and F. Winau. 2010. Lysosomal alpha-galactosidase controls the generation of self lipid antigens for natural killer T cells. Immunity. 33:216-228.
10. Fischer, K., E. Scotet, M. Niemeyer, H. Koebernick, J. Zerrahn, S. Maillet, R. Hurwitz, M. Kursar, M. Bonneville, S.H. Kaufmann, and U.E. Schaible. 2004. Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells. Proc. Natl. Acad. Sci. USA. 101:10685-10690.
11. Fujii, S., K. Shimizu, H. Hemmi, and R.M. Steinman. 2007. Innate Valpha14(+) natural killer T cells mature dendritic cells, leading to strong adaptive immunity. Immunol. Rev. 220:183-198.
12. Godfrey, D.I., and M. Kronenberg. 2004. Going both ways: immune regulation via CD1d-dependent NKT cells. J. Clin. Invest. 114:1379-1388.
13. Godfrey, D.I., D.G. Pellicci, O. Patel, L. Kjer-Nielsen, J. McCluskey, and J. Rossjohn. 2010a. Antigen recognition by CD1d-restricted NKT T cell receptors. Semin. Immunol. 22:61-67.
14. Godfrey, D.I., S. Stankovic, and A.G. Baxter. 2010b. Raising the NKT cell family. Nat. Immunol. 11:197-206.
15. Guillonneau, C., J.D. Mintern, F.X. Hubert, A.C. Hurt, G.S. Besra, S. Porcelli, I.G. Barr, P.C. Doherty, D.I. Godfrey, and S.J. Turner. 2009. Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity. Proc. Natl. Acad. Sci. USA. 106:3330-3335.
16. Hermans, I.F., J.D. Silk, U. Gileadi, S.H. Masri, D. Shepherd, K.J. Farrand, M. Salio, and V. Cerundolo. 2007. Dendritic cell function can be modulated through cooperative actions of TLR ligands and invariant NKT cells. J. Immunol. 178:2721-2729.
17. Kinjo, Y., D. Wu, G. Kim, G.W. Xing, M.A. Poles, D.D. Ho, M. Tsuji, K. Kawahara, C.H. Wong, and M. Kronenberg. 2005. Recognition of bacterial glycosphingolipids by natural killer T cells. Nature. 434:520-525.
18. Kinjo, Y., E. Tupin, D. Wu, M. Fujio, R. Garcia-Navarro, M.R. Benhnia, D.M. Zajonc, G. Ben-Menachem, G.D. Ainge, G.F. Painter, et al. 2006. Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat. Immunol. 7:978-986.
19. Lam, D., N. Ng, S. Lee, G. Batzer, and A.A. Horner. 2008. Airway house dust extract exposures modify allergen-induced airway hypersensitivity responses by TLR4-dependent and independent pathways. J. Immunol. 181:2925-2932.
20. Mallevaey, T., J.P. Scott-Browne, J.L. Matsuda, M.H. Young, D.G. Pellicci, O. Patel, M. Thakur, L. Kjer-Nielsen, S.K. Richardson, V. Cerundolo, et al. 2009. T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity. 31:60-71.
21. Mallevaey, T., A.J. Clarke, J. Scott-Browne, M.H. Young, D.G. Pellicci, O. Patel, J.L. Matsuda, J. Mccluskey, D.I. Godfrey, P. Marrack, et al. 2011. A molecular basis for NKT cell recognition of CD1d-self-antigen. Immunity. 34:315-326.
22. Mattner, J., K.L. Debord, N. Ismail, R.D. Goff, C. Cantu III, D. Zhou, P. Saint-Mezard, V. Wang, Y. Gao, N. Yin, et al. 2005. Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature. 434:525-529.
23. Matulis, G., J.P. Sanderson, N.M. Lissin, M.B. Asparuhova, G.R. Bommineni, D. Schümperli, R.R. Schmidt, P.M. Villiger, B.K. Jakobsen, and S.D. Gadola. 2010. Innate-like control of human iNKT cell autoreactivity via the hypervariable CDR3beta loop. PLoS Biol. 8:e1000402.
24. Meyer, E.H., S. Goya, O. Akbari, G.J. Berry, P.B. Savage, M. Kronenberg, T. Nakayama, R.H. Dekruyff, and D.T. Umetsu. 2006. Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells. Proc. Natl. Acad. Sci. USA. 103:2782-2787.
25. Michel, M.L., A.C. Keller, C. Paget, M. Fujio, F. Trottein, P.B. Savage, C.H. Wong, E. Schneider, M. Dy, and M.C. Leite-de-Moraes. 2007. Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia. J. Exp. Med. 204:995-1001.
26. Ng, N., D. Lam, P. Paulus, G. Batzer, and A.A. Horner. 2006. House dust extracts have both TH2 adjuvant and tolerogenic activities. J. Allergy Clin. Immunol. 117:1074-1081.
27. Paget, C., T. Mallevaey, A.O. Speak, D. Torres, J. Fontaine, K.C. Sheehan, M. Capron, B. Ryffel, C. Faveeuw, M. Leite de Moraes, et al. 2007. Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids. Immunity. 27:597-609.
28. Pellicci, D.G., O. Patel, L. Kjer-Nielsen, S.S. Pang, L.C. Sullivan, K. Kyparissoudis, A.G. Brooks, H.H. Reid, S. Gras, I.S. Lucet, et al. 2009. Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors. Immunity. 31:47-59.
29. Pichavant, M., S. Goya, E.H. Meyer, R.A. Johnston, H.Y. Kim, P. Matangkasombut, M. Zhu, Y. Iwakura, P.B. Savage, R.H. DeKruyff, et al. 2008. Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17. J. Exp. Med. 205:385-393.
30. Salio, M., A.O. Speak, D. Shepherd, P. Polzella, P.A. Illarionov, N. Veerapen, G.S. Besra, F.M. Platt, and V. Cerundolo. 2007. Modulation of human natural killer T cell ligands on TLRmediated antigen-presenting cell activation. Proc. Natl. Acad. Sci. USA. 104:20490-20495.
31. Schümann, J., M.P. Mycko, P. Dellabona, G. Casorati, and H.R. MacDonald. 2006. Cutting edge: influence of the TCR Vbeta domain on the selection of semi-invariant NKT cells by endogenous ligands. J. Immunol. 176: 2064-2068.
32. Scott-Browne, J.P., J.L. Matsuda, T. Mallevaey, J. White, N.A. Borg, J. McCluskey, J. Rossjohn, J. Kappler, P. Marrack, and L. Gapin. 2007. Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nat. Immunol. 8:1105-1113.
33. Sriram, V., W. Du, J. Gervay-Hague, and R.R. Brutkiewicz. 2005. Cell wall glycosphingolipids of Sphingomonas paucimobilis are CD1d-specific ligands for NKT cells. Eur. J. Immunol. 35:1692-1701.
34. Stanic, A.K., A.D. De Silva, J.J. Park, V. Sriram, S. Ichikawa, Y. Hirabyashi, K. Hayakawa, L. Van Kaer, R.R. Brutkiewicz, and S. Joyce. 2003. Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by beta-D-glucosylceramide synthase deficiency. Proc. Natl. Acad. Sci. USA. 100:1849-1854.
35. Thomas, S.Y., Y.H. Chyung, and A.D. Luster. 2010. Natural killer T cells are not the predominant T cell in asthma and likely modulate, not cause, asthma. J. Allergy Clin. Immunol. 125:980-984.
36. Umetsu, D.T., and R.H. Dekruyff. 2010. Natural killer T cells are important in the pathogenesis of asthma: the many pathways to asthma. J. Allergy Clin. Immunol. 125:975-979.
37. Venkataswamy, M.M., and S.A. Porcelli. 2010. Lipid and glycolipid antigens of CD1d-restricted natural killer T cells. Semin. Immunol. 22:68-78.
38. Wei, D.G., S.A. Curran, P.B. Savage, L. Teyton, and A. Bendelac. 2006. Mechanisms imposing the Vbeta bias of Valpha14 natural killer T cells and consequences for microbial glycolipid recognition. J. Exp. Med. 203:1197-1207.
39. Wingender, G., P. Rogers, G. Batzer, S.L. Myung, D. Bai, B. Pei, A. Khurana, M. Kronenberg, and A.A. Horner. 2011. Invariant NKT cells are crucial for airway inflammation induced by environmental antigens. J. Exp. Med. 208:1151-1162.
40. Wun, K.S., G. Cameron, O. Patel, S.S. Pang, D.G. Pellicci, L.C. Sullivan, S. Keshipeddy, M.H. Young, A.P. Uldrich, M. Thakur, et al. 2011. A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells. Immunity. 34:327-339.