Statins in neurological disorders: An overview and update

Pharmacological Research

Volumn 88, Issue , 2014, Pages 74-83

  Malfitano, Anna Maria ^a   Marasco, Giuseppe ^b,c   Proto, Maria Chiara ^a   Laezza, Chiara ^d   Gazzerro, Patrizia ^a   Bifulco, Maurizio ^a  

^a UNIVERSITY OF SALERNO   (Italy)

^b Neurologia Stroke Unit Azienda Ospedaliera Dei Colli Napoli   (Italy)

^c BOSTON UNIVERSITY   (United States)

^d CNR   (Italy)

Author keywords

Alzheimer disease; Multiple sclerosis; Neuro protection; Parkinson's disease; Primary brain tumors; Statins; Stroke

Indexed keywords

ATORVASTATIN; FLUINDOSTATIN; GELATINASE B; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; NITRIC OXIDE SYNTHASE; PITAVASTATIN; PRAVASTATIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ROSUVASTATIN; SIMVASTATIN; TISSUE PLASMINOGEN ACTIVATOR; TUMOR NECROSIS FACTOR ALPHA; XANTHINE OXIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MATRIX METALLOPROTEINASE; NEUROPROTECTIVE AGENT;

ACUTE KIDNEY FAILURE; ALZHEIMER DISEASE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ANTITHROMBOCYTIC ACTIVITY; APOPTOSIS; ATHEROSCLEROTIC CARDIOVASCULAR DISEASE; ATHEROSCLEROTIC PLAQUE; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; BRAIN TUMOR; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CAROTID ARTERY STENTING; CEREBROVASCULAR ACCIDENT; DEPRESSION; DISEASE SEVERITY; DOWN REGULATION; DRUG FATALITY; DRUG MECHANISM; DYSLIPIDEMIA; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; ENZYME INHIBITION; HEART PROTECTION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; IMMUNOMODULATION; ISCHEMIC HEART DISEASE; LIVER DYSFUNCTION; LIVER INJURY; LIVER TOXICITY; MULTIPLE SCLEROSIS; MYOGLOBINURIA; MYOPATHY; NEUROLOGIC DISEASE; NEUROPROTECTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVIEW; RHABDOMYOLYSIS; SIGNAL TRANSDUCTION; UPREGULATION; VASODILATATION; ANIMAL; METABOLISM; NERVOUS SYSTEM DISEASES;

ANIMALS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MATRIX METALLOPROTEINASES; NADPH OXIDASE; NERVOUS SYSTEM DISEASES; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE III; REACTIVE OXYGEN SPECIES;

EID: 84906790942     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2014.06.007     Document Type: Review

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