메뉴 건너뛰기




Volumn 133, Issue 1, 1997, Pages 51-59

HMG-CoA reductase inhibitors suppress macrophage growth induced by oxidized low density lipoprotein

Author keywords

Atherosclerosis; Foam cell; HMG CoA reductase inhibitor; Macrophage growth; Simvastatin

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN; MEVALONIC ACID; PRAVASTATIN; SIMVASTATIN; SQUALENE;

EID: 0030810427     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(97)00118-4     Document Type: Article
Times cited : (92)

References (50)
  • 1
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993;362:801-9.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 2
    • 0022591979 scopus 로고
    • The pathogenesis of atherosclerosis - An update
    • Ross R. The pathogenesis of atherosclerosis - an update. N Engl J Med 1986;314:488-500.
    • (1986) N Engl J Med , vol.314 , pp. 488-500
    • Ross, R.1
  • 4
    • 0025063716 scopus 로고
    • Macrophage and smooth muscle cell proliferation in atherosclerotic lesions of WHHL and comparably hypercholesterolemic fat-fed rabbits
    • Rosenfeld ME, Ross R. Macrophage and smooth muscle cell proliferation in atherosclerotic lesions of WHHL and comparably hypercholesterolemic fat-fed rabbits. Arteriosclerosis 1990;10:680-7.
    • (1990) Arteriosclerosis , vol.10 , pp. 680-687
    • Rosenfeld, M.E.1    Ross, R.2
  • 5
    • 0025854962 scopus 로고
    • Foam cells of the rabbit atherosclerotic plaque arrested in metaphase by colchicine show a macrophage phenotype
    • Spagnoli LG, Orlandi A, Santeusanio G. Foam cells of the rabbit atherosclerotic plaque arrested in metaphase by colchicine show a macrophage phenotype. Atherosclerosis 1991;88:87-92.
    • (1991) Atherosclerosis , vol.88 , pp. 87-92
    • Spagnoli, L.G.1    Orlandi, A.2    Santeusanio, G.3
  • 6
    • 0024603895 scopus 로고
    • Beyond cholesterol: Modification of low-density lipoprotein that increase its atherogenicity
    • Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol: modification of low-density lipoprotein that increase its atherogenicity. N Engl J Med 1989;320:915-24.
    • (1989) N Engl J Med , vol.320 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 8
    • 0028079980 scopus 로고
    • Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized low density lipoprotein on murine macrophages
    • Sakai M, Miyazaki A, Hakamata H, Sasaki T, Yui S, Yamazaki M, Shichiri M, Horiuchi S. Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized low density lipoprotein on murine macrophages. J Biol Chem 1994;269:31430-5.
    • (1994) J Biol Chem , vol.269 , pp. 31430-31435
    • Sakai, M.1    Miyazaki, A.2    Hakamata, H.3    Sasaki, T.4    Yui, S.5    Yamazaki, M.6    Shichiri, M.7    Horiuchi, S.8
  • 11
    • 0027185879 scopus 로고
    • Relationship between mevalonate pathway and arterial myocyte proliferation: In vitro studies with inhibitors of HMG-CoA reductase
    • Corsini A, Mazzotti M, Raiteri M, Soma MR, Gabbiani G, Fumagalli R, Paoletti R. Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase. Atherosclerosis 1993;101:117-25.
    • (1993) Atherosclerosis , vol.101 , pp. 117-125
    • Corsini, A.1    Mazzotti, M.2    Raiteri, M.3    Soma, M.R.4    Gabbiani, G.5    Fumagalli, R.6    Paoletti, R.7
  • 13
    • 0025009814 scopus 로고
    • Inhibition by 6-fluoromevalonate demonstrates that mevalonate or one of the mevalonate phosphates is necessary for lymphocyte proliferation
    • Cuthbert JA, Lipsky PE. Inhibition by 6-fluoromevalonate demonstrates that mevalonate or one of the mevalonate phosphates is necessary for lymphocyte proliferation. J Biol Chem 1990;265:18568-75.
    • (1990) J Biol Chem , vol.265 , pp. 18568-18575
    • Cuthbert, J.A.1    Lipsky, P.E.2
  • 14
    • 0021204120 scopus 로고
    • Evidence for post-translational incorporation of a product of mevalonic acid into Swiss 3T3 cell proteins
    • Schmidt RA, Schneider CJ, Glomset JA. Evidence for post-translational incorporation of a product of mevalonic acid into Swiss 3T3 cell proteins. J Biol Chem 1984;259:10175-80.
    • (1984) J Biol Chem , vol.259 , pp. 10175-10180
    • Schmidt, R.A.1    Schneider, C.J.2    Glomset, J.A.3
  • 15
    • 0026785265 scopus 로고
    • Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N′-bis(2-chloroethyl)-N-nitrosourea and β -interferon on human glioma cells
    • Soma MR, Pagliarini P, Butti G, Paoletti R, Paoletti P, Fumagalli R. Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N′-bis(2-chloroethyl)-N-nitrosourea and β -interferon on human glioma cells. Cancer Res 1992;52:4348-55.
    • (1992) Cancer Res , vol.52 , pp. 4348-4355
    • Soma, M.R.1    Pagliarini, P.2    Butti, G.3    Paoletti, R.4    Paoletti, P.5    Fumagalli, R.6
  • 16
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein JL, Brown MS. Regulation of the mevalonate pathway. Nature 1990;343:425-9.
    • (1990) Nature , vol.343 , pp. 425-429
    • Goldstein, J.L.1    Brown, M.S.2
  • 19
  • 21
    • 0025726579 scopus 로고
    • Prevention of restenosis by lovastatin after successful coronary angioplasty
    • Sahni R, Maniet AR, Voci G, Banka VS. Prevention of restenosis by lovastatin after successful coronary angioplasty. Am Heart J 1991;121:1600-8.
    • (1991) Am Heart J , vol.121 , pp. 1600-1608
    • Sahni, R.1    Maniet, A.R.2    Voci, G.3    Banka, V.S.4
  • 22
    • 0028071636 scopus 로고
    • Acetylated low density lipoprotein reduces its ligand activity for the scavenger receptor after interaction with reconstituted high density lipoprotein
    • Miyazaki A, Sakai M, Suginohara Y, Hakamata H, Sakamoto Y, Morikawa W, Horiuchi S. Acetylated low density lipoprotein reduces its ligand activity for the scavenger receptor after interaction with reconstituted high density lipoprotein. J Biol Chem 1994;269:5264-9.
    • (1994) J Biol Chem , vol.269 , pp. 5264-5269
    • Miyazaki, A.1    Sakai, M.2    Suginohara, Y.3    Hakamata, H.4    Sakamoto, Y.5    Morikawa, W.6    Horiuchi, S.7
  • 23
    • 0026500072 scopus 로고
    • Exposure of rat peritoneal macrophages to acetylated low density lipoprotein results in release of plasma membrane cholesterol
    • Shinohara M, Miyazaki A, Shichiri M, Morino Y, Horiuchi S. Exposure of rat peritoneal macrophages to acetylated low density lipoprotein results in release of plasma membrane cholesterol. J Biol Chem 1992;267:1603-8.
    • (1992) J Biol Chem , vol.267 , pp. 1603-1608
    • Shinohara, M.1    Miyazaki, A.2    Shichiri, M.3    Morino, Y.4    Horiuchi, S.5
  • 25
    • 0028176994 scopus 로고
    • Involvement of β2-microglobulin modified with advanced glycation endo products in the pathogenesis of hemodialysis-associated amyloidosis
    • Miyata T, Inagi R, Iida Y, Sato M, Yamada N, Oda O, Maeda K, Seo H. Involvement of β2-microglobulin modified with advanced glycation endo products in the pathogenesis of hemodialysis-associated amyloidosis. J Clin Invest 1994;93:521-8.
    • (1994) J Clin Invest , vol.93 , pp. 521-528
    • Miyata, T.1    Inagi, R.2    Iida, Y.3    Sato, M.4    Yamada, N.5    Oda, O.6    Maeda, K.7    Seo, H.8
  • 26
    • 0028172772 scopus 로고
    • Species difference in cholesteryl ester cycle and HDL-induced cholesterol efflux from macrophage foam cells
    • Hakamata H, Miyazaki A, Sakai M, Suginihara Y, Sakamoto Y-I, Horiuchi S. Species difference in cholesteryl ester cycle and HDL-induced cholesterol efflux from macrophage foam cells. Arterioscler Thromb 1994;14:1860-5.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1860-1865
    • Hakamata, H.1    Miyazaki, A.2    Sakai, M.3    Suginihara, Y.4    Sakamoto, Y.-I.5    Horiuchi, S.6
  • 27
    • 0019730393 scopus 로고
    • Factors regulating the activities of the low density lipoprotein receptor and the scavenger receptor on human monocyte-macrophages
    • Fogelman AM, Haberland ME, Seager J, Hokom M, Edwards. Factors regulating the activities of the low density lipoprotein receptor and the scavenger receptor on human monocyte-macrophages. J Lipid Res 1981;22:1131-41.
    • (1981) J Lipid Res , vol.22 , pp. 1131-1141
    • Fogelman, A.M.1    Haberland, M.E.2    Seager, J.3    Hokom, M.4    Edwards5
  • 29
    • 0018185320 scopus 로고
    • The picomol determination of free and total cholesterol
    • Heider JG, Boyett RL. The picomol determination of free and total cholesterol. J Lipid Res 1978;19:514-8.
    • (1978) J Lipid Res , vol.19 , pp. 514-518
    • Heider, J.G.1    Boyett, R.L.2
  • 30
    • 34548003946 scopus 로고
    • Efficient trace-labeling of proteins with iodine
    • McFarlane AS. Efficient trace-labeling of proteins with iodine. Nature 1958;182:53.
    • (1958) Nature , vol.182 , pp. 53
    • McFarlane, A.S.1
  • 31
    • 0028910142 scopus 로고
    • Differential effects of an acyl-coenzyme A: Cholesterolacyltransferase inhibitor on HDL-induced cholesterol efflux from rat macrophage foam cells
    • Hakamata H, Miyazaki A, Sakai M, Sakamoto Y, Matsuda H, Kihara K, Horiuchi S. Differential effects of an acyl-coenzyme A: cholesterolacyltransferase inhibitor on HDL-induced cholesterol efflux from rat macrophage foam cells. FEBS Lett 1995;363:29-32.
    • (1995) FEBS Lett , vol.363 , pp. 29-32
    • Hakamata, H.1    Miyazaki, A.2    Sakai, M.3    Sakamoto, Y.4    Matsuda, H.5    Kihara, K.6    Horiuchi, S.7
  • 32
    • 0020183575 scopus 로고
    • Regulation of synthesis and degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by low density lipoprotein and 25-hydroxycholesterol in UT-1 cells
    • Faust JR, Luskey KL, Chin DJ, Goldstein JL, Brown MS. Regulation of synthesis and degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by low density lipoprotein and 25-hydroxycholesterol in UT-1 cells. Proc Natl Acad Sci USA 1982;79:5205-9.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 5205-5209
    • Faust, J.R.1    Luskey, K.L.2    Chin, D.J.3    Goldstein, J.L.4    Brown, M.S.5
  • 33
    • 0029959824 scopus 로고    scopus 로고
    • The scavenger receptor serves as a route for internalization of lysophosphatidylcholine in oxidized low density lipoprotein-induced macrophage proliferation
    • Sakai M, Miyazaki A, Hakamata H, Kodama T, Suzuki H, Kobori S, Shichiri M, Horiuchi S. The scavenger receptor serves as a route for internalization of lysophosphatidylcholine in oxidized low density lipoprotein-induced macrophage proliferation. J Biol Chem 1996;271:27346-52.
    • (1996) J Biol Chem , vol.271 , pp. 27346-27352
    • Sakai, M.1    Miyazaki, A.2    Hakamata, H.3    Kodama, T.4    Suzuki, H.5    Kobori, S.6    Shichiri, M.7    Horiuchi, S.8
  • 34
    • 0026682810 scopus 로고
    • Inhibition of cultured vascular smooth muscle cell migration by simvastatin (MK-733)
    • Hidaka Y, Eda T, Yonemoto M, Kamei T. Inhibition of cultured vascular smooth muscle cell migration by simvastatin (MK-733). Atherosclerosis 1992;95:87-94.
    • (1992) Atherosclerosis , vol.95 , pp. 87-94
    • Hidaka, Y.1    Eda, T.2    Yonemoto, M.3    Kamei, T.4
  • 35
    • 0026641368 scopus 로고
    • Tissue selectivity of pravastatin sodium, lovastatin and simvastatin: The relation ship between inhibition of de novo sterol synthesis and active drug concentrations in the liver, spleen and testis in rat
    • Koga T, Fukuda K, Shimada Y, Fukami M, Koike H, Tsujita Y. Tissue selectivity of pravastatin sodium, lovastatin and simvastatin: the relation ship between inhibition of de novo sterol synthesis and active drug concentrations in the liver, spleen and testis in rat. Eur J Biochem 1992;209:315-9.
    • (1992) Eur J Biochem , vol.209 , pp. 315-319
    • Koga, T.1    Fukuda, K.2    Shimada, Y.3    Fukami, M.4    Koike, H.5    Tsujita, Y.6
  • 39
    • 0019305204 scopus 로고
    • Regulation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and Swiss 3T3 cells stimulated to divide by platelet-derived growth factor
    • Habenicht AJR, Glomset JA, Ross R. Regulation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and Swiss 3T3 cells stimulated to divide by platelet-derived growth factor. J Biol Chem 1980;255:5134-40.
    • (1980) J Biol Chem , vol.255 , pp. 5134-5140
    • Habenicht, A.J.R.1    Glomset, J.A.2    Ross, R.3
  • 40
    • 0021281136 scopus 로고
    • Relationship between mevalonate and mitogenesis in human fibroblasts stimulated with platelet-derived growth factor
    • Fairbanks KP, Witte LD, Goodman DS. Relationship between mevalonate and mitogenesis in human fibroblasts stimulated with platelet-derived growth factor. J Biol Chem 1984;259:1546-51.
    • (1984) J Biol Chem , vol.259 , pp. 1546-1551
    • Fairbanks, K.P.1    Witte, L.D.2    Goodman, D.S.3
  • 41
    • 0023917971 scopus 로고
    • Evidence for modification of lamin B by a product of mevalonic acid
    • Wolda SL, Glomset. Evidence for modification of lamin B by a product of mevalonic acid. J Biol Chem 1988;263:5997-6000.
    • (1988) J Biol Chem , vol.263 , pp. 5997-6000
    • Wolda, S.L.1    Glomset2
  • 43
    • 0023604660 scopus 로고
    • Isoprenylated proteins in cultured cells: Subcellular distribution and changes related to altered morphology and growth arrest induced by mevalonate deprivation
    • Maltese WA, Sheridan KM. Isoprenylated proteins in cultured cells: subcellular distribution and changes related to altered morphology and growth arrest induced by mevalonate deprivation. J Cell Physiol 1987;133:471-81.
    • (1987) J Cell Physiol , vol.133 , pp. 471-481
    • Maltese, W.A.1    Sheridan, K.M.2
  • 45
    • 0024406286 scopus 로고
    • All ras proteins are polyisoprenylated but only some are palmitoylated
    • Hancock JF, Magee AI, Childs JE, Marshall CJ. All ras proteins are polyisoprenylated but only some are palmitoylated. Cell 1989;57:1167-77.
    • (1989) Cell , vol.57 , pp. 1167-1177
    • Hancock, J.F.1    Magee, A.I.2    Childs, J.E.3    Marshall, C.J.4
  • 46
    • 0028300763 scopus 로고
    • Modulation of the mevalonate pathway and cell growth by pravastatin and d-limonene in a human hepatoma cell line (Hep G2)
    • Kawata S, Naqgase T, Yamasaki E, Ishiguro H, Matsuzawa Y. Modulation of the mevalonate pathway and cell growth by pravastatin and d-limonene in a human hepatoma cell line (Hep G2). Br J Cancer 1994;69:1015-20.
    • (1994) Br J Cancer , vol.69 , pp. 1015-1020
    • Kawata, S.1    Naqgase, T.2    Yamasaki, E.3    Ishiguro, H.4    Matsuzawa, Y.5
  • 47
    • 0024316475 scopus 로고
    • Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and human
    • Schafer WR, Kim R, Sterne R, Thorner J, Kim S-H, Rine J. Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and human. Science 1989;245:379-85.
    • (1989) Science , vol.245 , pp. 379-385
    • Schafer, W.R.1    Kim, R.2    Sterne, R.3    Thorner, J.4    Kim, S.-H.5    Rine, J.6
  • 49
    • 0026589912 scopus 로고
    • Lovastatin inhibits low-density lipoprotein oxidation and alters its fluidity and uptake by macrophages: In vitro and in vivo studies
    • Aviram M, Dankner G, Cogan U, Hochgraf E, Brook G. Lovastatin inhibits low-density lipoprotein oxidation and alters its fluidity and uptake by macrophages: in vitro and in vivo studies. Metabolism 1992;41:229-35.
    • (1992) Metabolism , vol.41 , pp. 229-235
    • Aviram, M.1    Dankner, G.2    Cogan, U.3    Hochgraf, E.4    Brook, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.