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Volumn 35, Issue 11 SUPPL. 1, 2004, Pages 2708-2711

Effects of statins on endothelium and signaling mechanisms

Author keywords

Acute care

Indexed keywords

ACTIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHOLESTEROL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FLUINDOSTATIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; NITRATE; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; RAC PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SIMVASTATIN; STATIN; SUPEROXIDE;

EID: 7644242146     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000143319.73503.38     Document Type: Conference Paper
Times cited : (153)

References (22)
  • 1
    • 0031443412 scopus 로고    scopus 로고
    • Endothelial function and oxidant stress
    • Harrison DG. Endothelial function and oxidant stress. Clin Cardiol. 1997;20(Suppl 2):II-11-II-7.
    • (1997) Clin Cardiol , vol.20 , Issue.2 SUPPL.
    • Harrison, D.G.1
  • 2
    • 1542345696 scopus 로고    scopus 로고
    • Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20 536 people with cerebrovascular disease and other high-risk conditions
    • Heart Protection Study Collaborative Group. Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20 536 people with cerebrovascular disease and other high-risk conditions. Lancet. 2004;363:757-767.
    • (2004) Lancet , vol.363 , pp. 757-767
  • 3
    • 0032826065 scopus 로고    scopus 로고
    • Neuroprotective properties of statins in cerebral ischemia and stroke
    • Vaughan CJ, Delanty N. Neuroprotective properties of statins in cerebral ischemia and stroke. Stroke. 1999;30:1969-1973.
    • (1999) Stroke , vol.30 , pp. 1969-1973
    • Vaughan, C.J.1    Delanty, N.2
  • 4
    • 0031032831 scopus 로고    scopus 로고
    • Simvastatin, an HMG-Coenzyme a reductase inhibitor, improves endothelium function within one month
    • O'Driscoll G, Green D, Taylor RR. Simvastatin, an HMG-Coenzyme A reductase inhibitor, improves endothelium function within one month. Circulation. 1997;95:1126-1131.
    • (1997) Circulation , vol.95 , pp. 1126-1131
    • O'Driscoll, G.1    Green, D.2    Taylor, R.R.3
  • 5
    • 0034617071 scopus 로고    scopus 로고
    • A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall
    • Gorlach A, Brandes RP, Nguyen K, Amidi M, Deghani F, Busse R. A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall. Circ Res. 2000;87:26-32.
    • (2000) Circ Res , vol.87 , pp. 26-32
    • Gorlach, A.1    Brandes, R.P.2    Nguyen, K.3    Amidi, M.4    Deghani, F.5    Busse, R.6
  • 6
    • 0035122832 scopus 로고    scopus 로고
    • Inhibition of geranylgeranylation reduces angiotensin II-mediated free radical production in vascular smooth muscle cells: Involvement of angiotensin AT1 receptor expression and Rac1 GTPAse
    • Wassmann S, Laufs U, Bäumer AT, Müller K, Konkol C, Sauer H, Böhm M, Nickenig G. Inhibition of geranylgeranylation reduces angiotensin II-mediated free radical production in vascular smooth muscle cells: involvement of angiotensin AT1 receptor expression and Rac1 GTPAse. Mol Pharmacol. 2001;59:646-654.
    • (2001) Mol Pharmacol , vol.59 , pp. 646-654
    • Wassmann, S.1    Laufs, U.2    Bäumer, A.T.3    Müller, K.4    Konkol, C.5    Sauer, H.6    Böhm, M.7    Nickenig, G.8
  • 7
    • 0343048978 scopus 로고    scopus 로고
    • Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation
    • Wagner AH, Kohler T, Ruckschloss U, Just I, Hecker M. Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation. Arterioscler Thromb Vasc Biol. 2000;20:61-69.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 61-69
    • Wagner, A.H.1    Kohler, T.2    Ruckschloss, U.3    Just, I.4    Hecker, M.5
  • 8
    • 0032584177 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors
    • Laufs U, La FV, Plutzky J, Liao JK. Upregulation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors. Circulation. 1998;97:1129-1135.
    • (1998) Circulation , vol.97 , pp. 1129-1135
    • Laufs, U.1    La, F.V.2    Plutzky, J.3    Liao, J.K.4
  • 9
    • 0032555154 scopus 로고    scopus 로고
    • Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase
    • Endres M, Laufs U, Huang Z, Nakamura T, Huang P, Moskowitz MA, Liao JK. Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proc Natl Acad Sci U S A. 1998;95:8880-8885.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8880-8885
    • Endres, M.1    Laufs, U.2    Huang, Z.3    Nakamura, T.4    Huang, P.5    Moskowitz, M.A.6    Liao, J.K.7
  • 10
    • 0346736491 scopus 로고    scopus 로고
    • Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells
    • Hernandez-Perera O, Perez-Sala D, Navarro-Antolin J, Sanchez-Pascuala R, Hernandez G, Diaz C, Lamas S. Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells. J Clin Invest. 1998;101:2711-2719.
    • (1998) J Clin Invest , vol.101 , pp. 2711-2719
    • Hernandez-Perera, O.1    Perez-Sala, D.2    Navarro-Antolin, J.3    Sanchez-Pascuala, R.4    Hernandez, G.5    Diaz, C.6    Lamas, S.7
  • 11
    • 0033826581 scopus 로고    scopus 로고
    • The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals
    • Kureishi Y, Luo Z, Shiojima I, Bialik A, Fulton D, Leer DJ, Sessa WC, Walsh K. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat Med. 2000;6:1004-1010.
    • (2000) Nat Med , vol.6 , pp. 1004-1010
    • Kureishi, Y.1    Luo, Z.2    Shiojima, I.3    Bialik, A.4    Fulton, D.5    Leer, D.J.6    Sessa, W.C.7    Walsh, K.8
  • 12
    • 0032508533 scopus 로고    scopus 로고
    • Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase
    • Laufs U, Liao JK. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. J Biol Chem. 1998;273:24266-24271.
    • (1998) J Biol Chem , vol.273 , pp. 24266-24271
    • Laufs, U.1    Liao, J.K.2
  • 14
    • 0034687606 scopus 로고    scopus 로고
    • Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription
    • Laufs U, Endres M, Custodis F, Gertz K, Nickenig G, Liao JK, Bohm M. Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription. Circulation. 2000;102:3104-3110.
    • (2000) Circulation , vol.102 , pp. 3104-3110
    • Laufs, U.1    Endres, M.2    Custodis, F.3    Gertz, K.4    Nickenig, G.5    Liao, J.K.6    Bohm, M.7
  • 17
    • 0037178764 scopus 로고    scopus 로고
    • Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice
    • 202
    • Vecchione C, Brandes RP. Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice. Circ Res. 202;91:173-179.
    • Circ Res , vol.91 , pp. 173-179
    • Vecchione, C.1    Brandes, R.P.2
  • 18
    • 0032488379 scopus 로고    scopus 로고
    • Increased thrombotic vascular events after change of statin
    • Thomas M, Mann J. Increased thrombotic vascular events after change of statin. Lancet. 1998;352:1830-1831.
    • (1998) Lancet , vol.352 , pp. 1830-1831
    • Thomas, M.1    Mann, J.2
  • 19
    • 0037177167 scopus 로고    scopus 로고
    • Withdrawal of statins increases event rates in patients with acute coronary syndromes
    • Heeschen C, Hamm CW, Laufs U, Snapinn S, Böhm M, White HD; for the Platelet Receptor Inhibition in Ischemic Syndrome Management (PRISM) Investigators. Withdrawal of statins increases event rates in patients with acute coronary syndromes. Circulation. 2002;105:1446-1452.
    • (2002) Circulation , vol.105 , pp. 1446-1452
    • Heeschen, C.1    Hamm, C.W.2    Laufs, U.3    Snapinn, S.4    Böhm, M.5    White, H.D.6
  • 21
    • 0035581239 scopus 로고    scopus 로고
    • Rapid effects on vascular function after initiation and withdrawal of atorvastastin in healthy, normocholesterolemic men
    • Laufs U, Wassmann S, Hilgers S, Ribaudo N, Böhm M, Nickenig G. Rapid effects on vascular function after initiation and withdrawal of atorvastastin in healthy, normocholesterolemic men. Am J Cardiol. 2001;88:1306-1307.
    • (2001) Am J Cardiol , vol.88 , pp. 1306-1307
    • Laufs, U.1    Wassmann, S.2    Hilgers, S.3    Ribaudo, N.4    Böhm, M.5    Nickenig, G.6
  • 22
    • 7644236194 scopus 로고    scopus 로고
    • Does early withdrawal of statin therapy in patients with acute coronary syndromes increase hospital morbidity and mortality?
    • Abstract 2435
    • Spencer FA, Fonarow GC, Frederick P, Wright RS, Every N, Dong W, Goldberg RJ, Lambrew C, French WJ. Does early withdrawal of statin therapy in patients with acute coronary syndromes increase hospital morbidity and mortality? Circulation 2002;106(suppl II):493. Abstract 2435.
    • (2002) Circulation , vol.106 , Issue.2 SUPPL. , pp. 493
    • Spencer, F.A.1    Fonarow, G.C.2    Frederick, P.3    Wright, R.S.4    Every, N.5    Dong, W.6    Goldberg, R.J.7    Lambrew, C.8    French, W.J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.